indomethacin has been researched along with Granuloma in 137 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report mycobacterial granulomatous inflammation in the ulcerated caecum of rats that received indomethacin." | 7.69 | Mycobacterial granulomatous inflammation in the ulcerated caecum of indomethacin-treated rats. ( Anthony, A; Billington, O; Dhillon, AP; Fidler, H; McFadden, J; Nygard, G; Pounder, RE; Wakefield, AJ, 1995) |
| "Indomethacin given continuously in the drinking water (20 micrograms/ml) to BALB/cAn pi mice during the latent period of pristane-induced plasmacytoma development dramatically reduced the plasmacytoma incidence from 34." | 7.67 | Inhibition of plasmacytoma development in BALB/c mice by indomethacin. ( Anderson, AO; Nordan, RP; Potter, M; Wax, JS, 1985) |
| "Seven-day-old carrageenin granuloma tissue of rats, when incubated in organ culture, produced 6-keto-prostaglandin F1 alpha, prostaglandin E2, prostaglandin F2 alpha, and thromboxane B2 in ratios of 16/7/1/1, respectively." | 7.66 | Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. ( Komabayashi, T; Levine, L; Ohuchi, K; Sato, H; Satoh, H; Tsurufuji, S, 1980) |
| "In this work the authors are concerned with the study of different amounts of calcium in granulomas induced by permanganate and treated with Indomethacin only or with Indomethacin plus Diflunisal." | 7.66 | [Calcium content of KMnO4 induced granuloma after treatment with 2 combined non-steroidal drugs: indomethacin plus diflunisal]. ( Conti, P; Continenza, MA; Gigante, GE, 1980) |
| "In the present work it was determined the ability of non-steroidal anti-inflammatory drugs (Diflunisal and Indomethacin) to inhibit formation of "granuloma pouch" exudate induced in rats." | 7.66 | ["Granuloma pouch" reduction after treatment with indomethacin and diflunisal and collateral effects of these drugs on gastric mucosa]. ( Alesse, E; Bruno, G; Cifone, MG; Conti, P; Continenza, MA, 1980) |
| "A 71-year-old man with non-lipemic, generalized, plane xanthomas developed nodules and tumors within one month of starting indomethacin therapy." | 7.65 | Plasma cell granulomas in non-lipemic xanthomatosis: apparent induction by indomethacin. ( Rawnsley, HM; Shelley, WB, 1975) |
| "Indomethacin treatment significantly decreased cotton pellet implantation induced white blood cell count elevation and immune cells infiltration in epididymal white adipose tissue." | 5.36 | Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model. ( Chen, W; Cheng, JT; Cheng, KC; Shen, KH; Wu, HT; Yeh, CH, 2010) |
| "Indomethacin was more potent than prednisolone against PGE2 (ID50 of< 0." | 5.29 | Differential effects of prednisolone and indomethacin on zymosan-induced inflammation in a modified murine tissue-chamber model. ( Dawson, J; Nguyen, H; Oluyomi, AO; Towbin, H; Vosbeck, K, 1995) |
| "Granulomas were associated with a significant decrease in anti-mycobacterial immunity manifested by a drop in delayed-type hypersensitivity reactions and antibody titres." | 5.29 | T-cell lung granulomas induced by sepharose-coupled Mycobacterium tuberculosis protein antigens: immunosuppressive phenomena reversed with cyclophosphamide and indomethacin. ( Hernández-Pando, R; Mancilla, R; Orozco, H, 1995) |
| "The anti-inflammatory activity of an ethanolic extract of Carica papaya leaves was investigated in rats using carrageenan induced paw oedema, cotton pellet granuloma and formaldehyde induced arthritis models." | 3.74 | Anti-inflammatory activities of ethanolic extract of Carica papaya leaves. ( Adebukola, OM; Funmilayo, AA; Owoyele, BV; Soladoye, AO, 2008) |
| " All the target compounds showed anti-inflammatory activity and three of them 3b, 3c and 4c surpassed that of indomethacin both locally and systemically in the cotton pellet granuloma and rat paw edema bioassay." | 3.74 | Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents. ( Abdel Ghany, YS; Ashour, HM; Baraka, A; Bekhit, AA; Bekhit, Ael-D, 2008) |
| " Four compounds were proved to be as active as indomethacin in animal models of inflammation." | 3.72 | Tetrazolo[1,5-a]quinoline as a potential promising new scaffold for the synthesis of novel anti-inflammatory and antibacterial agents. ( Aboulmagd, E; Bekhit, AA; El-Sayed, OA; Park, JY, 2004) |
| "The anti-inflammatory effect of the leaves of Bryonia laciniosa was evaluated using carrageenan, dextran, histamine, serotonin induced rat paw oedema and cotton pellet induced granuloma (chronic) models in rats." | 3.72 | Evaluation of anti-inflammatory activity of chloroform extract of Bryonia laciniosa in experimental animal models. ( Gupta, M; Karki, SS; Manikandan, L; Mazumdar, UK; Sambathkumar, R; Sivakumar, T; Vamsi, ML, 2003) |
| " The effects of C-1 on the acute phase of inflammation were studied in formaldehyde-induced edema." | 3.71 | An investigation of the antiinflammatory effects of an extract from Cladonia rangiformis HOFFM. ( Aslan, A; Gepdiremen, A; Göçer, F; Güvenalp, Z; Süleyman, H; Yildirim, D, 2002) |
| "We report mycobacterial granulomatous inflammation in the ulcerated caecum of rats that received indomethacin." | 3.69 | Mycobacterial granulomatous inflammation in the ulcerated caecum of indomethacin-treated rats. ( Anthony, A; Billington, O; Dhillon, AP; Fidler, H; McFadden, J; Nygard, G; Pounder, RE; Wakefield, AJ, 1995) |
| "Oxaceprol, an established therapeutic agent for osteoarthritis, had no effect on macrophage prostaglandin E2 release in vitro and inhibited carrageenan paw oedema at high doses (18-150 mg/kg p." | 3.69 | Oxaceprol, an atypical inhibitor of inflammation and joint damage. ( Brune, K; Ionac, M; Parnham, MJ; Plauchithiu, M, 1996) |
| " These models of acute and chronic inflammation, and the antimitotic model permitted us to evaluate the anti-inflammatory and antimitotic effects of sulindac, ibuprofen, naproxen and glucametacin." | 3.69 | Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque. ( Akatsu, T; Consolaro, A; Guimarães, SA; Tago, EM, 1996) |
| " Local administration of anti-inflammatory drugs such as dexamethasone, indomethacin, or a PLA2 inhibitor such as p-bromophenacyl bromide significantly inhibited exudate volume, cellular influx, granuloma formation, exudate PGE2 levels and PLA2 activity, to varying degrees." | 3.68 | Time-course of phospholipase A2, eicosanoid release and cellular accumulation in rat immunological air pouch inflammation. ( Moreno, JJ, 1993) |
| "The antiinflammatory activity of a new 14-membered macrolide antibiotic, roxithromycin, was evaluated in various rat models including carrageenan- and poly-L-arginine-induced hind-paw oedema, croton oil inflamed ear assay and polyester sponge granuloma." | 3.68 | Macrolide antibiotics as antiinflammatory agents: roxithromycin in an unexpected role. ( Agen, C; Blandizzi, C; Costa, M; Danesi, R; Del Tacca, M; Favini, P; Stacchini, B, 1993) |
| "The antireactive activity of glucosamine sulfate (GS) (CAS 29031-19-4) was tested in the rat in experimental models of subacute inflammation (sponge granuloma and croton oil granuloma), on subacute mechanical arthritis (kaolin arthritis) and in immunological-reactive arthritis and generalized inflammation (adjuvant arthritis)." | 3.68 | Antiarthritic effects of glucosamine sulfate studied in animal models. ( Pacini, MA; Revel, L; Setnikar, I, 1991) |
| " Lysosomal enzymes such as acid phosphatase, beta-glucuronidase and succinate dehydrogenase are known to be liberated during the maturation of mononuclear phagocytes to epithelioid cell granulomas." | 3.68 | Histochemical analysis of experimental granulomatous uveitis. ( Biswas, J; Kristeva, M; Pararajasegaram, G; Rao, NA; Sevanian, A, 1991) |
| " The anti-inflammatory properties of FPP028 were evaluated through the carrageenan induced paw edema and the cotton pellet induced granuloma and compared with the activity of indomethacin, phenylbutazone, and isoxicam; as a result, the activity of FPP028 was shown to be similar to that of the latter compounds." | 3.67 | Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent. ( Banchelli, G; Bianchini, F; Ignesti, G; Pecori-Vettori, L; Pirisino, R; Rafanelli, D; Raimondi, L, 1986) |
| "Indomethacin given continuously in the drinking water (20 micrograms/ml) to BALB/cAn pi mice during the latent period of pristane-induced plasmacytoma development dramatically reduced the plasmacytoma incidence from 34." | 3.67 | Inhibition of plasmacytoma development in BALB/c mice by indomethacin. ( Anderson, AO; Nordan, RP; Potter, M; Wax, JS, 1985) |
| "Seven-day-old carrageenin granuloma tissue of rats, when incubated in organ culture, produced 6-keto-prostaglandin F1 alpha, prostaglandin E2, prostaglandin F2 alpha, and thromboxane B2 in ratios of 16/7/1/1, respectively." | 3.66 | Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. ( Komabayashi, T; Levine, L; Ohuchi, K; Sato, H; Satoh, H; Tsurufuji, S, 1980) |
| " The anti-inflammatory activity of Indomethacin, Oxametacine and Phenylbutazone was evaluated in these animals using paw oedema provoked by carrageenan granulomas induced by cotton pellets and polyarthritis induced by Freund complete adjuvant." | 3.66 | The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents. ( Cirillo, R; Curzio, M; Franzone, J; Sena, L; Torrielli, MV, 1981) |
| "The deposit of calcium in experimental granulomas as determined by X-ray fluorescence is notably decreased by orally given indomethacin and diflunisal." | 3.66 | Calcium content of experimental granuloma as determined by X-ray fluorescence. Influence of non-steroid antiinflammatory drugs. ( Conti, P; Continenza, MA; Gigante, GE, 1980) |
| "A combination of indomethacin and diflunisal, a new salicylic acid derivative, when given to rats, gave a greater reduction in the size of permanganate induced granulomas and less gastric irritation, than either drug given alone." | 3.66 | Decreased ulcerogenic effect of indomethacin in the rat when given in association with diflunisal. ( Conti, P; Continenza, A, 1980) |
| "In this work the authors are concerned with the study of different amounts of calcium in granulomas induced by permanganate and treated with Indomethacin only or with Indomethacin plus Diflunisal." | 3.66 | [Calcium content of KMnO4 induced granuloma after treatment with 2 combined non-steroidal drugs: indomethacin plus diflunisal]. ( Conti, P; Continenza, MA; Gigante, GE, 1980) |
| "In the present work it was determined the ability of non-steroidal anti-inflammatory drugs (Diflunisal and Indomethacin) to inhibit formation of "granuloma pouch" exudate induced in rats." | 3.66 | ["Granuloma pouch" reduction after treatment with indomethacin and diflunisal and collateral effects of these drugs on gastric mucosa]. ( Alesse, E; Bruno, G; Cifone, MG; Conti, P; Continenza, MA, 1980) |
| "A 71-year-old man with non-lipemic, generalized, plane xanthomas developed nodules and tumors within one month of starting indomethacin therapy." | 3.65 | Plasma cell granulomas in non-lipemic xanthomatosis: apparent induction by indomethacin. ( Rawnsley, HM; Shelley, WB, 1975) |
| "Flumizole is a potent anti-inflammatory agent in animal models with an inhibitory activity severalfold that of indomethacin in rat foot edema and prostaglandin synthetase tests." | 3.65 | Flumizole, a new nonsteroidal anti-inflammatory agent. ( Bettis, JW; McIlhenny, HM; Wiseman, EH, 1975) |
| " In a rat paw edema test for anti-inflammatory activity naproxen was 55 times more active than aspirin." | 3.65 | Chemistry and pharmacology of naproxen. ( Dorfman, RI, 1975) |
| "mays husk decoction for the treatment of pain and inflammatory conditions in Nigerian folk medicine." | 1.36 | Analgesic and anti-inflammatory effects of aqueous extract of Zea mays husk in male Wistar rats. ( Ibidapo, AJ; Negedu, MN; Oguntoye, SO; Olaniran, SO; Onasanwo, SA; Owoyele, BV; Oyeleke, SA; Sanya, JO; Soladoye, AO, 2010) |
| "Indomethacin treatment significantly decreased cotton pellet implantation induced white blood cell count elevation and immune cells infiltration in epididymal white adipose tissue." | 1.36 | Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model. ( Chen, W; Cheng, JT; Cheng, KC; Shen, KH; Wu, HT; Yeh, CH, 2010) |
| "Oedema was induced by: a) AA (0." | 1.30 | Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. ( González, R; Ledón, N; Romay, C, 1998) |
| "Granulomas were associated with a significant decrease in anti-mycobacterial immunity manifested by a drop in delayed-type hypersensitivity reactions and antibody titres." | 1.29 | T-cell lung granulomas induced by sepharose-coupled Mycobacterium tuberculosis protein antigens: immunosuppressive phenomena reversed with cyclophosphamide and indomethacin. ( Hernández-Pando, R; Mancilla, R; Orozco, H, 1995) |
| "Indomethacin was more potent than prednisolone against PGE2 (ID50 of< 0." | 1.29 | Differential effects of prednisolone and indomethacin on zymosan-induced inflammation in a modified murine tissue-chamber model. ( Dawson, J; Nguyen, H; Oluyomi, AO; Towbin, H; Vosbeck, K, 1995) |
| " The lower dosage of 4 mg was effective throughout and there was little to be gained by increasing the dose as further reduction of granuloma size was not obtained." | 1.29 | OM-89 modulation of chronic inflammation: relevance to clinical use. ( Gowland, G; Moore, AR; Willis, D; Willoughby, DA, 1995) |
| "Oral treatment with prednisolone and cyclosporin A of zymosan-challenged animals showed a dose-dependent reduction of IL-1 beta concentrations, but no effect of indomethacin." | 1.29 | Interleukin-1 (IL-1) production in a mouse tissue chamber model of inflammation. II. Identification of (tissue) macrophages as the IL-1 producing cells and the effect of anti-inflammatory drugs. ( Chaplin, D; Dawson, J; Geiger, T; Kunz, S; Nguyen, H; Rordorf-Adam, C; Towbin, H; Vosbeck, K; Zingel, O, 1993) |
| " Thus, CP-331 exerted anti-inflammatory, analgesic, and antipyretic effects but without showing gastric toxicity, which is a common side effect of anti-inflammatory drugs." | 1.28 | Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate. ( Abe, T; Itokazu, Y; Ohya, O; Omata, T; Segawa, Y; Tagashira, E; Tsuzuike, N; Ueda, I; Yoshida, K, 1992) |
| "mansoni eggs in patients with chronic intestinal schistosomiasis and do so by inducing macrophages to secrete prostaglandins." | 1.28 | Granulomatous hypersensitivity to Schistosoma mansoni egg antigens in human schistosomiasis. III. In vitro granuloma modulation induced by immune complexes. ( Doughty, BL; Gazzinelli, G; Goes, AM; Katz, N; Rocha, R, 1991) |
| " In rats, dosed orally with 5 mg/kg [14C]-oxametacine, there is a 2." | 1.27 | Distribution of oxametacine and its anti-inflammatory metabolites in inflamed tissues of rats. ( Strobel, K; Szelenyi, I; Vergin, H, 1983) |
| "Nabumetone is a compound of novel structure which displays acute anti-inflammatory activity in the carrageenan-induced oedema model in rats and the ultraviolet-induced erythema model in guinea-pigs." | 1.26 | Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agent. ( Boyle, EA; Freeman, PC; Mangan, FR; Thomson, MJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (68.61) | 18.7374 |
| 1990's | 24 (17.52) | 18.2507 |
| 2000's | 9 (6.57) | 29.6817 |
| 2010's | 9 (6.57) | 24.3611 |
| 2020's | 1 (0.73) | 2.80 |
| Authors | Studies |
|---|---|
| Ackrell, J | 1 |
| Antonio, Y | 1 |
| Franco, F | 1 |
| Landeros, R | 1 |
| Leon, A | 1 |
| Muchowski, JM | 1 |
| Maddox, ML | 1 |
| Nelson, PH | 1 |
| Rooks, WH | 2 |
| Roszkowski, AP | 3 |
| Wallach, MB | 1 |
| Toja, E | 1 |
| Selva, D | 2 |
| Schiatti, P | 2 |
| Bekhit, AA | 3 |
| Ashour, HM | 1 |
| Abdel Ghany, YS | 1 |
| Bekhit, Ael-D | 1 |
| Baraka, A | 1 |
| Youssef, AM | 1 |
| White, MS | 1 |
| Villanueva, EB | 1 |
| El-Ashmawy, IM | 2 |
| Klegeris, A | 1 |
| Fahmy, HT | 1 |
| Rostom, SA | 1 |
| El-Din A Bekhit, A | 1 |
| Rizk, OH | 1 |
| Shaaban, OG | 1 |
| Nwaehujor, C | 1 |
| Chinthaka, SWGJW | 1 |
| Satarasinghe, RL | 1 |
| Senanayake, S | 1 |
| Weerarathne, WAPSR | 1 |
| Anfaz, AAM | 1 |
| Deraniyagala, MP | 1 |
| Owoyele, BV | 2 |
| Adebukola, OM | 1 |
| Funmilayo, AA | 1 |
| Soladoye, AO | 2 |
| Negedu, MN | 1 |
| Olaniran, SO | 1 |
| Onasanwo, SA | 1 |
| Oguntoye, SO | 1 |
| Sanya, JO | 1 |
| Oyeleke, SA | 1 |
| Ibidapo, AJ | 1 |
| Efimova, LA | 1 |
| Krylova, SG | 1 |
| Zueva, EP | 1 |
| Khotimchenko, IuS | 1 |
| Khotimchenko, MIu | 1 |
| Wu, HT | 1 |
| Chen, W | 1 |
| Cheng, KC | 1 |
| Yeh, CH | 1 |
| Shen, KH | 1 |
| Cheng, JT | 1 |
| Madhusudana, K | 1 |
| Shireesha, B | 1 |
| Naidu, VG | 1 |
| Ramakrishna, S | 1 |
| Narsaiah, B | 1 |
| Rao, AR | 1 |
| Diwan, PV | 1 |
| Barreto, RR | 1 |
| Franco, Ede S | 1 |
| Brasileiro, CF | 1 |
| de Oliveira, AP | 1 |
| Dimech, GS | 1 |
| Malta, DJ | 1 |
| Cazuzu, JS | 1 |
| Leite, AC | 1 |
| da Silva, TG | 1 |
| Maia, MB | 1 |
| Meléndez Camargo, ME | 1 |
| Buendía Romero, M | 1 |
| Ramos Zamora, D | 1 |
| Cardona Carrillo, P | 1 |
| Villarreal Maldonado, ME | 1 |
| Arunachalam, G | 1 |
| Chattopadhyay, D | 1 |
| Chatterjee, S | 1 |
| Mandal, AB | 1 |
| Sur, TK | 1 |
| Mandal, SC | 1 |
| Gupta, M | 1 |
| Mazumdar, UK | 1 |
| Sivakumar, T | 1 |
| Vamsi, ML | 1 |
| Karki, SS | 1 |
| Sambathkumar, R | 1 |
| Manikandan, L | 1 |
| WINTER, CA | 2 |
| RISLEY, EA | 2 |
| NUSS, GW | 1 |
| El-Sayed, OA | 1 |
| Aboulmagd, E | 1 |
| Park, JY | 1 |
| Singh, VP | 1 |
| Patil, CS | 1 |
| Kulkarni, SK | 1 |
| Fang, QM | 1 |
| Zhang, H | 1 |
| Cao, Y | 1 |
| Wang, C | 1 |
| Winder, CV | 1 |
| Birnie, JH | 1 |
| Sutton, BM | 1 |
| Zuccarello, M | 1 |
| Rush, JA | 1 |
| Bragt, PC | 1 |
| Bonta, IL | 1 |
| Boyle, EA | 1 |
| Freeman, PC | 1 |
| Mangan, FR | 2 |
| Thomson, MJ | 1 |
| Balestrieri, B | 1 |
| Capasso, L | 1 |
| Masiello, S | 1 |
| Castaldo, S | 1 |
| Capasso, F | 1 |
| De Maroussem, D | 1 |
| Pipy, B | 1 |
| Beraud, M | 1 |
| Derache, R | 1 |
| Kunkel, SL | 3 |
| Chensue, SW | 1 |
| Mouton, C | 1 |
| Higashi, GI | 2 |
| Vergin, H | 1 |
| Strobel, K | 1 |
| Szelenyi, I | 1 |
| Ohuchi, K | 1 |
| Sato, H | 1 |
| Komabayashi, T | 1 |
| Tsurufuji, S | 5 |
| Satoh, H | 1 |
| Levine, L | 1 |
| Jacobi, H | 2 |
| Dell, HD | 2 |
| Bluth, R | 1 |
| Wada, Y | 1 |
| Etoh, Y | 1 |
| Ohira, A | 1 |
| Tsukamoto, M | 1 |
| Nakamura, M | 1 |
| Bailey, PJ | 1 |
| Sturm, A | 1 |
| Lopez-Ramos, B | 1 |
| Breier, P | 1 |
| Sena, L | 1 |
| Torrielli, MV | 1 |
| Franzone, J | 1 |
| Curzio, M | 1 |
| Cirillo, R | 1 |
| Sugishita, E | 1 |
| Amagaya, S | 1 |
| Ogihara, Y | 1 |
| Continenza, MA | 3 |
| Conti, P | 4 |
| Gigante, GE | 2 |
| Boyle, E | 1 |
| Continenza, A | 1 |
| Cifone, MG | 1 |
| Alesse, E | 1 |
| Bruno, G | 1 |
| Willis, D | 1 |
| Moore, AR | 1 |
| Gowland, G | 1 |
| Willoughby, DA | 2 |
| Jiménez-Hernández, RM | 1 |
| Frechilla, D | 2 |
| Lasheras, B | 2 |
| Gutiérrez-Ríos, MT | 1 |
| Parrondo, E | 2 |
| Craciunescu, G | 2 |
| Cenarruzabeita, E | 1 |
| Anthony, A | 1 |
| Dhillon, AP | 1 |
| Fidler, H | 1 |
| McFadden, J | 1 |
| Billington, O | 1 |
| Nygard, G | 1 |
| Pounder, RE | 1 |
| Wakefield, AJ | 1 |
| Dawson, J | 2 |
| Rordorf-Adam, C | 1 |
| Geiger, T | 1 |
| Towbin, H | 2 |
| Kunz, S | 1 |
| Nguyen, H | 2 |
| Zingel, O | 1 |
| Chaplin, D | 1 |
| Vosbeck, K | 2 |
| Moreno, JJ | 1 |
| Agen, C | 1 |
| Danesi, R | 1 |
| Blandizzi, C | 1 |
| Costa, M | 1 |
| Stacchini, B | 1 |
| Favini, P | 1 |
| Del Tacca, M | 1 |
| Hernández-Pando, R | 1 |
| Orozco, H | 1 |
| Mancilla, R | 1 |
| Oluyomi, AO | 1 |
| Agha, AM | 1 |
| Gad, MZ | 1 |
| Ionac, M | 1 |
| Parnham, MJ | 1 |
| Plauchithiu, M | 1 |
| Brune, K | 1 |
| Guimarães, SA | 1 |
| Akatsu, T | 1 |
| Tago, EM | 1 |
| Consolaro, A | 1 |
| Raza, M | 1 |
| Dhariwal, MA | 1 |
| Ageel, AM | 1 |
| Qureshi, S | 1 |
| Romay, C | 1 |
| Ledón, N | 1 |
| González, R | 1 |
| Carbajal, D | 1 |
| Molina, V | 1 |
| Valdés, S | 1 |
| Arruzazabala, ML | 1 |
| Más, R | 1 |
| Magraner, J | 1 |
| Süleyman, H | 1 |
| Yildirim, D | 1 |
| Aslan, A | 1 |
| Göçer, F | 1 |
| Gepdiremen, A | 1 |
| Güvenalp, Z | 1 |
| Shelley, WB | 1 |
| Rawnsley, HM | 1 |
| Vogel, HG | 1 |
| Koshihara, Y | 1 |
| Yamagishi, M | 1 |
| Murota, SI | 2 |
| Chang, WC | 1 |
| Volterra, G | 1 |
| Del Soldato, P | 1 |
| Meli, A | 1 |
| Wiseman, EH | 2 |
| McIlhenny, HM | 1 |
| Bettis, JW | 1 |
| Lassman, HB | 1 |
| Kirby, RE | 1 |
| Wilker, JC | 1 |
| Mc Fadden, AR | 1 |
| Aultz, DE | 1 |
| Hoffman, D | 1 |
| Helsley, GC | 1 |
| Novick, WJ | 1 |
| Takesue, EI | 1 |
| Perrine, JW | 1 |
| Trapold, JH | 1 |
| Kulonen, E | 2 |
| Potila, M | 1 |
| Dorfman, RI | 1 |
| Fanelli, O | 1 |
| Nakamura, H | 1 |
| Shimizu, M | 1 |
| Segawa, Y | 1 |
| Ohya, O | 1 |
| Abe, T | 1 |
| Omata, T | 1 |
| Tsuzuike, N | 1 |
| Itokazu, Y | 1 |
| Yoshida, K | 1 |
| Tagashira, E | 1 |
| Ueda, I | 1 |
| Honmura, A | 1 |
| Yanase, M | 1 |
| Obata, J | 1 |
| Haruki, E | 1 |
| Grau, M | 1 |
| Guasch, J | 1 |
| Montero, JL | 1 |
| Felipe, A | 1 |
| Carrasco, E | 1 |
| Juliá, S | 1 |
| Kristeva, M | 1 |
| Biswas, J | 1 |
| Pararajasegaram, G | 1 |
| Sevanian, A | 2 |
| Rao, NA | 2 |
| Setnikar, I | 1 |
| Pacini, MA | 1 |
| Revel, L | 1 |
| Goes, AM | 1 |
| Gazzinelli, G | 1 |
| Rocha, R | 1 |
| Katz, N | 1 |
| Doughty, BL | 1 |
| Chiba, K | 1 |
| Goto, M | 1 |
| Shirota, H | 1 |
| Elliott, DE | 2 |
| Ragheb, S | 1 |
| Wellhausen, SR | 1 |
| Boros, DL | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT01943136] | Phase 1 | 128 participants (Anticipated) | Interventional | 2013-08-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for indomethacin and Granuloma
| Article | Year |
|---|---|
Pharmacological properties of naproxen.
Topics: Administration, Oral; Administration, Topical; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory A | 1973 |
1 trial available for indomethacin and Granuloma
| Article | Year |
|---|---|
Ketoprofen: a preliminary report of its pharmacological activity and therapeutic efficacy in rheumatic disorders.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Arthritis, Rheumatoid; Benzophenones; Bra | 1974 |
135 other studies available for indomethacin and Granuloma
| Article | Year |
|---|---|
Synthesis and antiinflammatory activity of 6,11-dihydro-11-oxodibenzo[b,e]thiepinalkanoic acids and related compounds.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Exp | 1978 |
3-Alkyl-2-aryl-3H-naphth[1,2-d]imidazoles, a novel class of nonacidic antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Drug Evaluation, Preclini | 1984 |
Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Carrageenan; Cyclooxygenase 1; C | 2008 |
Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Edema; Gran | 2010 |
Synthesis and biological evaluation of some thiazolylpyrazole derivatives as dual anti-inflammatory antimicrobial agents.
Topics: Animals; Anti-Bacterial Agents; Candida albicans; Carrageenan; Catalytic Domain; Cotton Fiber; Cyclo | 2010 |
Design, synthesis and biological evaluation of some novel thienopyrimidines and fused thienopyrimidines as anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Chemistry Techniques, Synthetic; Drug Design; Edema; Formaldehyde | 2012 |
Ficus vogelii methanol leaf extract ameliorates inflammation and arthritis by modulating osmotic fragility in C57BL/6J mice.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Diclofenac; Edema; Ficus; G | 2021 |
Noncaseating suppurative granulomatous lymphadenitis in adult onset Still's disease - a diagnostic dilemma in a tuberculosis-endemic region: a case report.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Fe | 2018 |
Anti-inflammatory activities of ethanolic extract of Carica papaya leaves.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carica; Carrageenan; Dose-Response Relat | 2008 |
Analgesic and anti-inflammatory effects of aqueous extract of Zea mays husk in male Wistar rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Dose-Response Relationship, Drug; F | 2010 |
[Experimental investigation of antiinflammatory and anesthetic properties of calcium pectate].
Topics: Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Female; Granuloma | 2010 |
Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model.
Topics: Adipose Tissue; Animals; Cell Movement; Cotton Fiber; Cyclooxygenase 2; Dinoprostone; Disease Models | 2010 |
Anti-inflammatory potential of thienopyridines as possible alternative to NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Line; Cytokines; Dis | 2012 |
Early undernutrition is associated with attenuated inflammatory response and alteration in pharmacological efficacy of indomethacin in rats.
Topics: Analysis of Variance; Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; C | 2012 |
Study of the anti-inflammatory effect of Sedum praealtum (Siempreviva) in the rat: dose-dependent response.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Count; Diclofenac; Dose-Response Relationship | 2002 |
Evaluation of anti-inflammatory activity of Alstonia macrophylla Wall ex A. DC. leaf extract.
Topics: Acute Disease; Alstonia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chronic Dise | 2002 |
Evaluation of anti-inflammatory activity of chloroform extract of Bryonia laciniosa in experimental animal models.
Topics: Animals; Anti-Inflammatory Agents; Bryonia; Carrageenan; Chloroform; Dextrans; Edema; Exudates and T | 2003 |
ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITIES OF INDOMETHACIN, 1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID.
Topics: Acetates; Adrenalectomy; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents | 1963 |
Tetrazolo[1,5-a]quinoline as a potential promising new scaffold for the synthesis of novel anti-inflammatory and antibacterial agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; G | 2004 |
Anti-inflammatory effect of licofelone against various inflammatory challenges.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase Inhibitors; Dose-Response R | 2006 |
Anti-inflammatory and free radical scavenging activities of ethanol extracts of three seeds used as "Bolengguazi".
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Cucurbitaceae; Dose-Response Relationship, | 2007 |
Experimental observations on flufenamic, mefenamic, and meclofenamic acids. I. Pharmacology.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Chemistry, Physical; E | 1966 |
Some anti-inflammatory properties of 8-trifluoromethylphenothiazine-1-carboxylic acid (SK & F 22908).
Topics: Animals; Erythema; Flufenamic Acid; Granuloma; Guinea Pigs; Indomethacin; Male; Phenothiazines; Phen | 1967 |
Indomethacin inhibits the in vivo formation of the lipoxygenase product HETE (12-hydroxy-5,8,10,14-eicosatetraenoic acid) during granulomatous inflammation in the rat.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acids; Carrageenan; Granuloma; Indo | 1980 |
Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agent.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Butanones; F | 1982 |
[Scopolamine and its pharmacological effects on some experimental inflammation tests].
Topics: Animals; Carrageenan; Cellulose; Dextrans; Edema; Flufenamic Acid; Granuloma; Indomethacin; Inflamma | 1980 |
The effects of locally injected antibiotic on carrageenan-induced granuloma in rats.
Topics: Animals; Body Weight; Carrageenan; Chloramphenicol; Collagen; Glycosaminoglycans; Granuloma; Indomet | 1984 |
Role of lipoxygenase products in murine pulmonary granuloma formation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Female; Granuloma; Histocomp | 1984 |
Distribution of oxametacine and its anti-inflammatory metabolites in inflamed tissues of rats.
Topics: Animals; Anti-Inflammatory Agents; Biotransformation; Granuloma; Hindlimb; Indomethacin; Male; Rats; | 1983 |
Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Carrageenan; Culture Techniques; Cycloheximide; Dexamethasone | 1980 |
[On the pharmacodynamics of acemetacin (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cats; Central Nervous Sy | 1980 |
[Comparison of the effect of 3-amino-4-mercapto-6-methylpyridazine with various antiphlogistic agents in rat models of inflammation].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Di | 1982 |
[Anti-inflammatory effects of acemetacin (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capillary Permeability; Edema; Erythema; | 1982 |
A biochemical study of the cotton pellet granuloma in the rat. Effects of dexamethasone and indomethacin.
Topics: Acetylglucosaminidase; Animals; Dexamethasone; Disease Models, Animal; Gossypium; Granuloma; Indomet | 1982 |
[Anti-inflammatory action of acemetacin (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Edema; Erythema; Female; Granuloma; Hyal | 1980 |
The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema; | 1981 |
Anti-inflammatory testing methods: comparative evaluation of mice and rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Cyproheptadine; Edema; Female; | 1981 |
Calcium content of experimental granuloma as determined by X-ray fluorescence. Influence of non-steroid antiinflammatory drugs.
Topics: Animals; Calcium; Diflunisal; Granuloma; Indomethacin; Male; Rats; Spectrometry, X-Ray Emission | 1980 |
The histology and collagen content of cotton pellet and polyvinyl sponge-induced granulomas in normal and drug-treated rats.
Topics: Aminopropionitrile; Animals; Collagen; Dexamethasone; DNA; Female; Gossypium; Granuloma; Indomethaci | 1980 |
Decreased ulcerogenic effect of indomethacin in the rat when given in association with diflunisal.
Topics: Animals; Diflunisal; Drug Therapy, Combination; Granuloma; Indomethacin; Male; Rats; Salicylates; St | 1980 |
[Calcium content of KMnO4 induced granuloma after treatment with 2 combined non-steroidal drugs: indomethacin plus diflunisal].
Topics: Animals; Diflunisal; Drug Interactions; Granuloma; Indomethacin; Male; Potassium Permanganate; Rats; | 1980 |
["Granuloma pouch" reduction after treatment with indomethacin and diflunisal and collateral effects of these drugs on gastric mucosa].
Topics: Animals; Diflunisal; Disease Models, Animal; Gastric Mucosa; Granuloma; Indomethacin; Male; Rats; Sa | 1980 |
OM-89 modulation of chronic inflammation: relevance to clinical use.
Topics: Adjuvants, Immunologic; Animals; Antigens, Bacterial; Chronic Disease; Drug Synergism; Escherichia c | 1995 |
Inhibition of inflammation and gastric damage in rats by copper (II) complexes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Behavior, Animal; Carrageenan; | 1995 |
Mycobacterial granulomatous inflammation in the ulcerated caecum of indomethacin-treated rats.
Topics: Animals; Cecal Diseases; Cecum; Granuloma; Indomethacin; Male; Mycobacterium Infections; Opportunist | 1995 |
Interleukin-1 (IL-1) production in a mouse tissue chamber model of inflammation. II. Identification of (tissue) macrophages as the IL-1 producing cells and the effect of anti-inflammatory drugs.
Topics: Animals; Cyclosporine; Diffusion Chambers, Culture; Dinoprostone; Dose-Response Relationship, Drug; | 1993 |
Time-course of phospholipase A2, eicosanoid release and cellular accumulation in rat immunological air pouch inflammation.
Topics: Acetophenones; Animals; Antigen-Antibody Complex; Arachidonic Acid; Cell Movement; Dexamethasone; Di | 1993 |
Macrolide antibiotics as antiinflammatory agents: roxithromycin in an unexpected role.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Croton Oil; Dis | 1993 |
T-cell lung granulomas induced by sepharose-coupled Mycobacterium tuberculosis protein antigens: immunosuppressive phenomena reversed with cyclophosphamide and indomethacin.
Topics: Animals; Antigens, Bacterial; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Electrophoresis, Polya | 1995 |
Differential effects of prednisolone and indomethacin on zymosan-induced inflammation in a modified murine tissue-chamber model.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Exudates a | 1995 |
Lipid peroxidation and lysosomal integrity in different inflammatory models in rats: the effects of indomethacin and naftazone.
Topics: Acetylglucosaminidase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Ca | 1995 |
Oxaceprol, an atypical inhibitor of inflammation and joint damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Dinoprostone | 1996 |
Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Division; Cell Wall; | 1996 |
Evaluation of the antiinflammatory activity of sodium valproate in rats and mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Body Temperature Regulation; Car | 1996 |
Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Disease Models, Animal; Ear Diseases; Edema; Fo | 1998 |
Anti-inflammatory activity of D-002: an active product isolated from beeswax.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carrageenan; Fatty Alcoh | 1998 |
An investigation of the antiinflammatory effects of an extract from Cladonia rangiformis HOFFM.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Edema; Formaldehyd | 2002 |
Plasma cell granulomas in non-lipemic xanthomatosis: apparent induction by indomethacin.
Topics: Aged; Blood Cell Count; Granuloma; Humans; Indomethacin; Male; Pain; Plasma Cells; Skin; Time Factor | 1975 |
Mechanical and chemical properties of various connective tissue organs in rats as influenced by non-steroidal antirheumatic drugs.
Topics: Animals; Aspirin; Biomechanical Phenomena; Bone and Bones; Cartilage; Collagen; Connective Tissue; G | 1977 |
Effect of salicyclic acid on gluccorticoid receptor in cultured fibroblasts derived from rat carrageenin granuloma.
Topics: Animals; Carrageenan; Cell Line; Cycloheximide; Cytosol; Dexamethasone; Fibroblasts; Granuloma; Indo | 1976 |
Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma.
Topics: Animals; Arachidonic Acids; Aspirin; Carrageenan; Depression, Chemical; Granuloma; Hydrocortisone; I | 1978 |
Indomethacin: relationship between ulcerogenic and anti-inflammatory properties. I. Effects of an intestinal lesion-preventing fat-free diet on anti-edema and anti-granuloma properties of indomethacin in the rat.
Topics: Animals; Body Weight; Dietary Fats; Edema; Fatty Acids, Essential; Granuloma; Indomethacin; Inflamma | 1978 |
Flumizole, a new nonsteroidal anti-inflammatory agent.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Biological Availability; Cyclooxygenase Inh | 1975 |
Pharmacology of a new non-steroidal, anti-inflammatory agent: 6,11-dihydro-11-oxodibenz [b, e] oxepin-2-acetic acid (HP 549).
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dibenzoxepins; Ede | 1977 |
The anti-inflammatory profile of proquazone.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Granuloma; Indomethaci | 1976 |
Effect of the administration of antirheumatic drugs on experimental granuloma in rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cellulose; Cytidine; Granuloma; Hexosamines; Hydroxyprol | 1975 |
Chemistry and pharmacology of naproxen.
Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Ed | 1975 |
Some pharmacological properties of 2-aryl-1,3-indandione derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticoagulants; Antitussive Agents; Drug Evaluation, | 1975 |
Effect of anti-inflammatory agents on accelerated granuloma formation in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Flufenamic Acid; Granuloma; Indomethacin; | 1975 |
Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; E | 1992 |
Therapeutic effect of Ga-Al-As diode laser irradiation on experimentally induced inflammation in rats.
Topics: Aluminum; Animals; Arsenic; Blood Proteins; Body Water; Capillary Permeability; Carrageenan; Dermati | 1992 |
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary | 1991 |
Histochemical analysis of experimental granulomatous uveitis.
Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Crystallins; Disease Models, Ani | 1991 |
Antiarthritic effects of glucosamine sulfate studied in animal models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Croton Oil; Gl | 1991 |
Granulomatous hypersensitivity to Schistosoma mansoni egg antigens in human schistosomiasis. III. In vitro granuloma modulation induced by immune complexes.
Topics: Alprostadil; Animals; Antibodies; Antibodies, Helminth; Antigen-Antibody Complex; Antigens, Helminth | 1991 |
A novel inhibitor of IL-1 generation, E5090: in vivo inhibitory effect on the generation of IL-1-like factor and on granuloma formation in an air-pouch model.
Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Exudates and Transudates; | 1991 |
Interactions between adherent mononuclear cells and lymphocytes from granulomas of mice with schistosomiasis mansoni.
Topics: Animals; Antigens, Helminth; Concanavalin A; Granuloma; Immune Tolerance; Indomethacin; Interferon T | 1990 |
Anti-inflammatory activity of some copper(II) complexes.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 1990 |
Role of iron in carrageenan-induced granuloma: action of desferrioxamine and indometacin.
Topics: Animals; Carrageenan; Deferoxamine; Dinoprostone; Exudates and Transudates; Granuloma; Indomethacin; | 1990 |
[Mechanism of action of pronase on chronic proliferative inflammation including granuloma angiogenesis in mice].
Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Granuloma; Hydrocortisone; Hydroxyproline; Indom | 1986 |
Induction of a silica air-pouch granuloma in rat.
Topics: Acute-Phase Proteins; Animals; Collagen; Cyclophosphamide; Female; Granuloma; Indomethacin; Inflamma | 1988 |
Synthesis and pharmacological evaluation of conjugates of prednisolone and non-steroidal anti-inflammatory agents.
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Cor | 1989 |
The effect of anti-inflammatory agents on the uptake of 67Ga into experimental granuloma.
Topics: Animals; Anti-Inflammatory Agents; Citrates; Citric Acid; Dexamethasone; Gallium Radioisotopes; Gran | 1989 |
Increased serum immunoreactive prolyl hydroxylase in rats with carrageenan-induced granuloma and adjuvant arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Benzopyrans; C | 1988 |
Treatment of experimental granulomatous uveitis by lipoxygenase and cyclo-oxygenase inhibitors.
Topics: Animals; Crystallins; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Granuloma; Immune Com | 1987 |
Characterization of regulatory (interferon-alpha/beta) and accessory (LAF/IL 1) monokine activities from liver granuloma macrophages of Schistosoma mansoni-infected mice.
Topics: Animals; Antigens, Helminth; Antiviral Agents; Female; Granuloma; Indomethacin; Interferon Type I; I | 1987 |
Suppression of natural killer cytolytic activity in mice undergoing pulmonary granulomatous inflammation.
Topics: Animals; Cytotoxicity, Immunologic; Foreign-Body Reaction; Granuloma; Immune Tolerance; Indomethacin | 1988 |
Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 1986 |
Interleukin 1 and prostaglandin production by cells of the mononuclear phagocyte system isolated from mycobacterial granulomas.
Topics: Animals; Cell Division; Cells, Cultured; Female; Fibroblasts; Granuloma; Guinea Pigs; Histocompatibi | 1987 |
Pharmacological activity and toxicity of apyramide: comparison with non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1987 |
Drug effects on a novel model of connective tissue breakdown.
Topics: Animals; Arthritis, Rheumatoid; Cartilage; Connective Tissue; Cyclophosphamide; Disease Models, Anim | 1987 |
[Anti-inflammatory effect of topically applied pranoprofen-gel].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Benzopyrans; Capillary Permeability; Ede | 1985 |
Inhibition of plasmacytoma development in BALB/c mice by indomethacin.
Topics: Animals; Arthritis; Ascitic Fluid; Carcinogens; Female; Granuloma; Indomethacin; Mice; Mice, Inbred | 1985 |
Pharmacological manipulation of the chronic granulomatous reactions in the livers of mice infected with schistosomiasis.
Topics: Animals; Granuloma; Indomethacin; Liver Diseases, Parasitic; Mice; Praziquantel; Schistosoma mansoni | 1985 |
The effects of a human plasma fraction on adjuvant arthritis and granuloma pellet reactions in the rat.
Topics: Animals; Arthritis, Rheumatoid; Freund's Adjuvant; Gossypium; Granuloma; Humans; Indomethacin; Plasm | 1974 |
[Anti-inflammatory principle synthesized by a strain of Serratia sp].
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Bromelains; Carrageenan; Chymotrypsin; Ed | 1969 |
Study of biochemical effects of anti-inflammatory drugs in carrageenin induced oedema and cotton pellet granuloma.
Topics: Adenosine Triphosphatases; Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain; Edema; | 1968 |
[The effect of indomethacin in inflammation].
Topics: Animals; Anti-Inflammatory Agents; Aorta; Glycosaminoglycans; Gossypium; Granulation Tissue; Granulo | 1971 |
The mode of action of hydrocortisone on the protein metabolism in rat carrageenin granuloma.
Topics: Animals; Betamethasone; Carrageenan; Cycloheximide; Granuloma; Hydrocortisone; In Vitro Techniques; | 1970 |
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D | 1971 |
[General pharmacological properties of methiazinic acid (16091 RP)].
Topics: Abscess; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Autonomic Nervous Syste | 1969 |
Anti-inflammatory, analgesic and antipyretic activities of 6-chloro-5-cyclohexylindan-1-carboxylic acid (TAI-284).
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Bronchodilator Agents; Capillary Permeabil | 1971 |
Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles.
Topics: Administration, Oral; Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Carrageenan; | 1974 |
[Biochemical studies on action mechnism of a new anti-inflammatory agent, naproxen (1). Effects of naproxen on changes in connective tissue components due to inflammation].
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Connective Tissue; Dimethylamines; Female; Gran | 1974 |
[Pharmacologic properties of a new, nonsteroidal anti-inflammatory agent, bucloxic acid (804 CB)].
Topics: Administration, Oral; Adrenal Glands; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Cycl | 1974 |
Antiinflammatory activity and other pharmacological properties of phthalazino(2,3-b)phthalazine-5,12(7H, 14H)-dione (Diftalone).
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Diuresis; Drug Ev | 1974 |
Effects of serotonin, indomethacin and other antirheumatic drugs on the synthesis of collagen and other proteins in granulation tissue slices.
Topics: Animals; Bradykinin; Collagen; Epinephrine; Granulation Tissue; Granuloma; Histamine; Hydroxyproline | 1972 |
Synthesis and pharmacology of a novel anti-inflammatory agent, ID-1619.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; Chemical Phenomena | 1972 |
Anti-inflammatory polysaccharide produced by Serratia piscatorum.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Edema; Granuloma; Hydrocortisone; Indicators and | 1974 |
Granulomatous hepatitis and prolonged fever of unknown origin: a study of 13 patients.
Topics: Adult; Ascites; Dexamethasone; Edema; Female; Fever; Fever of Unknown Origin; Granuloma; Hepatitis; | 1973 |
The role of sulfhydryl groups in three models of inflammatory disease.
Topics: Animals; Arthritis; Carrageenan; Croton Oil; Cyclophosphamide; Cysteine; Dexamethasone; Disulfides; | 1973 |
Bis(dimethylamino)-s-triazinyl antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Dimethylamines; Edema; Foot; Granuloma; Indomethacin; Kaolin; Let | 1973 |
New analgesic-anti-inflammatory drugs. 1-Oxo-2-substituted isoindoline derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Drug Evaluation, Preclinical; Edema; Gra | 1973 |
Pharmacological study on a new analgesic-anti-inflammatory drug: alpha-(4-(1-oxo-2-iso-indolinyl)-phenyl)-propionic acid of K 4277.
Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Behavi | 1973 |
[Pharmacology of butylmalonic acidmono-(1,2-diphenylhydrazide)-calcium (bumadizone-calcium)].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Blood Pr | 1973 |
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 2. On subacute inflammation].
Topics: Acute Disease; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis; Body Weight; Ed | 1973 |
Antiinflammatory activity of the new mould metabolite 11-desacetoxy-wortmannin and of some of its derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Coumarins; Dexamethasone; Edema; Freund's | 1974 |
Quinuclidine chemistry. 2. Synthesis and antiinflammatory properties of 2-substituted benzhydryl-3-quinuclidinols.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Benzene Derivatives; Carrageenan; Edema; Granuloma | 1974 |
Effects of anti-inflammatory drugs on glutathione levels and liver succinic dehydrogenase activity in carrageenin edema and cotton pellet granuloma in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Glutathione; Gossypium; Granuloma; Hydrocorti | 1972 |
Anti-inflammatory activity of an essential oil from Zanthoxylum budrunga.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Carrageenan; Edema; Female; Formaldehyde; Fruit; G | 1972 |
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid; | 1972 |
Anti-inflammatory and analgetic properties of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen).
Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Fe | 1971 |
3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent.
Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Car | 1971 |
[A comparative study on various antiphlogistics].
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Asbestos; Dextrans; Disease Models, Animal; Dr | 1971 |
5-Benzoyl-1-methylpyrrole-2-acetic acids as antiinflammatory agents.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Benzoates; Carrageenan; Edema; Granuloma; Indomethacin; | 1971 |
The effect of locally injected anti-inflammatory drugs on the synthesis of collagen and non-collagen protein of carrageenin granuloma in rats.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Body Weight; Carrageenan; Collagen; Granuloma; Hyd | 1969 |
[Influence of various drugs on the tissue permeability. 5. Comparison of the potency of various anti-inflammatory agents by the dermal tissue permeability test using filter paper implanted subcutaneously in the ventral region of rats].
Topics: Administration, Oral; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Azepines; Bromelains; | 1970 |
Anti-inflammatory and related properties of 4-(p-biphenylyl)-3-hydroxybutyric acid.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Pressure; Bronchial | 1968 |
The effect of locally injected anti-inflammatory drugs on the carrageenin granuloma in rats.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Body Weight; Carrageenan; Collagen; Diet; Granulom | 1969 |
Barium perforation of a peptic ulcer and barium granuloma of the colon. A report of two rare complications in radiological examination.
Topics: Arthritis, Rheumatoid; Barium; Colon; Duodenum; Esophagus; Granuloma; Humans; Indomethacin; Male; Mi | 1969 |
[On the inflammation inhibitory effect of (-)-alpha-bisabolol, an essential component of chamomilla oil].
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cycloparaffins; Edema; Female; Granuloma; Indomethac | 1969 |
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo | 1969 |
Synthesis and pharmacology of a new potential anti-inflammatory drug, 1-(3',4'-methylenedioxybenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid (ID-955).
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Blood Proteins; Capillary Permeability; Car | 1969 |
[Action of formalin on the cotton pellet granuloma test].
Topics: Animals; Anti-Inflammatory Agents; Formaldehyde; Gossypium; Granuloma; Indomethacin; Inflammation; M | 1964 |
[On the pharmacology of 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole acetic acid, a new antiphlogistic agent].
Topics: Animals; Granuloma; Indomethacin; Rats | 1965 |