indomethacin has been researched along with Graft vs Host Disease in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wren, SM | 1 |
| Wepsic, HT | 1 |
| Larson, CH | 1 |
| De Silva, MA | 1 |
| Mizushima, Y | 1 |
| Howell, CD | 1 |
| Yoder, TY | 1 |
| Vierling, JM | 1 |
| Klingemann, HG | 1 |
| Tsoi, MS | 1 |
| Storb, R | 1 |
| Choi, KL | 1 |
| Maier, T | 1 |
| Holda, JH | 1 |
| Claman, HN | 1 |
| Popovic, S | 1 |
| Bartlett, RR | 1 |
5 other studies available for indomethacin and Graft vs Host Disease
| Article | Year |
|---|---|
Inhibition of the graft-versus-host response by BCGcw-induced suppressor cells or prostaglandin E1.
Topics: Animals; Aspirin; BCG Vaccine; Graft vs Host Disease; Graft vs Host Reaction; Immune Tolerance; Indo | 1983 |
Suppressor function of liver mononuclear cells isolated during murine chronic graft-vs-host disease. II. Role of prostaglandins and interferon-gamma.
Topics: Animals; Antibodies; Cell Division; Cell Separation; Cells, Cultured; Chronic Disease; Female; Graft | 1992 |
Inhibition of prostaglandin E2 restores defective lymphocyte proliferation and cell-mediated lympholysis in recipients after allogeneic marrow grafting.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Dinoprostone; Female; Graft | 1986 |
Suppression of cytotoxic T-cell generation by natural suppressor cells from mice with GVHD is partially reversed by indomethacin.
Topics: Animals; Cell Communication; Cytotoxicity, Immunologic; Female; Graft vs Host Disease; Indomethacin; | 1988 |
The use of the murine chronic graft vs host (CGVH) disease, a model for systemic lupus erythematosus (SLE), for drug discovery.
Topics: Animals; Cyclophosphamide; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Graft vs Ho | 1987 |