indomethacin has been researched along with Glomerulosclerosis, Focal Segmental in 11 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The cyclooxygenase inhibitor indomethacin reduces proteinuria in patients with focal segmental glomerulosclerosis (FSGS) or other glomerular diseases." | 7.71 | Indomethacin protects permeability barrier from focal segmental glomerulosclerosis serum. ( McCarthy, ET; Sharma, M, 2002) |
| "Among the difficulties encountered, premature labor and polyhydramnios are common." | 5.28 | Indomethacin therapy and chronic hemodialysis during pregnancy. A case report. ( Dolkart, LA; Eshwar, KP; Reimers, FT, 1992) |
| " The cyclooxygenase inhibitor indomethacin reduces proteinuria in patients with focal segmental glomerulosclerosis (FSGS) or other glomerular diseases." | 3.71 | Indomethacin protects permeability barrier from focal segmental glomerulosclerosis serum. ( McCarthy, ET; Sharma, M, 2002) |
| "A four-year-old girl with growth failure and clinical and laboratory evidence of Bartter's syndrome responded to indomethacin treatment with decreased urinary prostaglandin excretion, symptomatic and chemical improvement, and accelerated growth." | 3.67 | Reversal of Bartter's syndrome by renal transplantation in a child with focal, segmental glomerular sclerosis. ( Blethen, SL; Jennette, JC; Lorentz, WB; Van Wyk, JJ, 1985) |
| "Primary focal segmental glomerulosclerosis (FSGS) recurs in nearly 30% of patients who progress to end-stage renal disease and then receive a kidney transplant." | 1.30 | Circulating factor in patients with recurrent focal segmental glomerulosclerosis postrenal transplantation inhibits expression of inducible nitric oxide synthase and nitric oxide production by cultured rat mesangial cells. ( Franki, N; Futterweit, S; Savin, V; Sharma, M; Sharma, R; Singhal, PC; Trachtman, H, 1999) |
| "Among the difficulties encountered, premature labor and polyhydramnios are common." | 1.28 | Indomethacin therapy and chronic hemodialysis during pregnancy. A case report. ( Dolkart, LA; Eshwar, KP; Reimers, FT, 1992) |
| "70 cases of focal glomerulosclerosis (FGS) followed for periods ranging from 1 to 24 years are reported." | 1.26 | Focal glomerulosclerosis: natural history and treatment. A report of 70 cases. ( Alphonse, JC; Beaufils, H; Guedon, J; Legrain, M, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ponticelli, C | 1 |
| Banfi, G | 1 |
| Imbasciati, E | 1 |
| Tarantino, A | 1 |
| Kooijmans-Coutinho, MF | 1 |
| Tegzess, AM | 1 |
| Bruijn, JA | 1 |
| Florijn, KW | 1 |
| van Es, LA | 1 |
| van der Woude, FJ | 1 |
| Keane, WF | 1 |
| O'Donnell, MP | 1 |
| Kasiske, BL | 1 |
| Kim, Y | 1 |
| Kacprzyk, F | 1 |
| Chrzanowski, W | 1 |
| Kubala, L | 1 |
| Orłowski, Z | 1 |
| Trachtman, H | 1 |
| Futterweit, S | 1 |
| Singhal, PC | 1 |
| Franki, N | 1 |
| Sharma, M | 2 |
| Sharma, R | 1 |
| Savin, V | 1 |
| McCarthy, ET | 1 |
| Simon, NM | 1 |
| Rosenberg, MJ | 1 |
| Lindeman, RD | 1 |
| Beaufils, H | 1 |
| Alphonse, JC | 1 |
| Guedon, J | 1 |
| Legrain, M | 1 |
| Dolkart, LA | 1 |
| Eshwar, KP | 1 |
| Reimers, FT | 1 |
| Blethen, SL | 1 |
| Van Wyk, JJ | 1 |
| Lorentz, WB | 1 |
| Jennette, JC | 1 |
2 reviews available for indomethacin and Glomerulosclerosis, Focal Segmental
| Article | Year |
|---|---|
Immunosuppressive therapy in primary glomerulonephritis (pros).
Topics: Adrenocorticotropic Hormone; Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulone | 1982 |
Medical treatment of glomerular diseases.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Child; Chlorambucil; Cyclophosphamid | 1978 |
1 trial available for indomethacin and Glomerulosclerosis, Focal Segmental
| Article | Year |
|---|---|
[Results of two year use of dipyridamole and metindol in patients with primary focal and (or) segmental glomerulosclerosis].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dipyridamole; Female; Glomerulosclerosis | 1997 |
8 other studies available for indomethacin and Glomerulosclerosis, Focal Segmental
| Article | Year |
|---|---|
Indomethacin treatment of recurrent nephrotic syndrome and focal segmental glomerulosclerosis after renal transplantation.
Topics: Adult; Female; Glomerulosclerosis, Focal Segmental; Humans; Indomethacin; Kidney Transplantation; Ma | 1993 |
Oxidative modification of low-density lipoproteins by mesangial cells.
Topics: Antioxidants; Arachidonic Acid; Butylated Hydroxytoluene; Catalase; Cell Division; Cells, Cultured; | 1993 |
Circulating factor in patients with recurrent focal segmental glomerulosclerosis postrenal transplantation inhibits expression of inducible nitric oxide synthase and nitric oxide production by cultured rat mesangial cells.
Topics: Animals; Blood Proteins; Cell Survival; Cells, Cultured; Cyclosporine; Glomerular Mesangium; Glomeru | 1999 |
Indomethacin protects permeability barrier from focal segmental glomerulosclerosis serum.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Albumins; Animals; Anti-Inflamma | 2002 |
Drug treatment of the chronic idiopathic glomerulopathies.
Topics: Adrenal Cortex Hormones; Alkylating Agents; B-Lymphocytes; Chronic Disease; Dipyridamole; Folic Acid | 1977 |
Focal glomerulosclerosis: natural history and treatment. A report of 70 cases.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Child; Female; Follow-Up St | 1978 |
Indomethacin therapy and chronic hemodialysis during pregnancy. A case report.
Topics: Adult; Female; Glomerulosclerosis, Focal Segmental; Humans; Indomethacin; Infant, Newborn; Obstetric | 1992 |
Reversal of Bartter's syndrome by renal transplantation in a child with focal, segmental glomerular sclerosis.
Topics: Alkalosis; Child, Preschool; Female; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Humans | 1985 |