indomethacin has been researched along with Glomerulonephritis, IGA in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Glomerulonephritis, IGA: A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When indomethacin was added to enalapril treatment, a further significant reduction in urinary proteins and fractional albumin clearance was observed." | 2.69 | The antiproteinuric effect of angiotensin antagonism in human IgA nephropathy is potentiated by indomethacin. ( Azzollini, N; Mister, M; Perico, N; Remuzzi, A; Remuzzi, G; Ruggenenti, P; Sangalli, F, 1998) |
| "The early stage of progressive IgA nephropathy was defined as having moderate proteinuria between 1 and 2 g/day, creatinine clearance values of 70 ml/min or more, and a histological severity score of 7 or more." | 2.68 | Steroid therapy during the early stage of progressive IgA nephropathy. A 10-year follow-up study. ( Hiki, Y; Horii, A; Kobayashi, Y; Kokubo, T; Tateno, S, 1996) |
| "We assume this is a rare form of MPGN, not associated with liver disease or other systemic diseases." | 1.32 | IgA-associated glomerulonephritis with membranoproliferative glomerulonephritis-like pattern in two children. ( Iitaka, K; Motoyama, O; Ogawa, N; Sekine, T; Tamai, S; Yamamoto, A, 2003) |
| "Forty seven patients with IgA glomerulonephritis (GN) were studied." | 1.27 | [Clinical, immunological and therapeutic research in mesangial immunoglobulin-A glomerulonephritis]. ( Belovezhdov, N; Robeva, R, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iitaka, K | 1 |
| Yamamoto, A | 1 |
| Ogawa, N | 1 |
| Sekine, T | 1 |
| Tamai, S | 1 |
| Motoyama, O | 1 |
| Zucchelli, P | 1 |
| Zuccalà, A | 1 |
| Santoro, A | 1 |
| Degli Esposti, E | 1 |
| Sturani, A | 1 |
| Chiarini, C | 1 |
| Belovezhdov, N | 1 |
| Robeva, R | 1 |
| Kobayashi, Y | 1 |
| Hiki, Y | 1 |
| Kokubo, T | 1 |
| Horii, A | 1 |
| Tateno, S | 1 |
| Perico, N | 1 |
| Remuzzi, A | 1 |
| Sangalli, F | 1 |
| Azzollini, N | 1 |
| Mister, M | 1 |
| Ruggenenti, P | 1 |
| Remuzzi, G | 1 |
2 trials available for indomethacin and Glomerulonephritis, IGA
| Article | Year |
|---|---|
Steroid therapy during the early stage of progressive IgA nephropathy. A 10-year follow-up study.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dipyridamole; Disease Prog | 1996 |
The antiproteinuric effect of angiotensin antagonism in human IgA nephropathy is potentiated by indomethacin.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflam | 1998 |
3 other studies available for indomethacin and Glomerulonephritis, IGA
| Article | Year |
|---|---|
IgA-associated glomerulonephritis with membranoproliferative glomerulonephritis-like pattern in two children.
Topics: Anti-Inflammatory Agents; Biopsy; Cell Division; Child; Child, Preschool; Female; Glomerular Mesangi | 2003 |
Characteristics of hypertension in primary IgA glomerulonephritis.
Topics: Adolescent; Adult; Aldosterone; Child; Female; Glomerulonephritis, IGA; Humans; Hypertension; Indome | 1984 |
[Clinical, immunological and therapeutic research in mesangial immunoglobulin-A glomerulonephritis].
Topics: Acenocoumarol; Adolescent; Adult; Antigen-Antibody Complex; Azathioprine; Chronic Disease; Complemen | 1984 |