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indomethacin and Glomerulonephritis, IGA

indomethacin has been researched along with Glomerulonephritis, IGA in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Glomerulonephritis, IGA: A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE.

Research Excerpts

ExcerptRelevanceReference
"When indomethacin was added to enalapril treatment, a further significant reduction in urinary proteins and fractional albumin clearance was observed."2.69The antiproteinuric effect of angiotensin antagonism in human IgA nephropathy is potentiated by indomethacin. ( Azzollini, N; Mister, M; Perico, N; Remuzzi, A; Remuzzi, G; Ruggenenti, P; Sangalli, F, 1998)
"The early stage of progressive IgA nephropathy was defined as having moderate proteinuria between 1 and 2 g/day, creatinine clearance values of 70 ml/min or more, and a histological severity score of 7 or more."2.68Steroid therapy during the early stage of progressive IgA nephropathy. A 10-year follow-up study. ( Hiki, Y; Horii, A; Kobayashi, Y; Kokubo, T; Tateno, S, 1996)
"We assume this is a rare form of MPGN, not associated with liver disease or other systemic diseases."1.32IgA-associated glomerulonephritis with membranoproliferative glomerulonephritis-like pattern in two children. ( Iitaka, K; Motoyama, O; Ogawa, N; Sekine, T; Tamai, S; Yamamoto, A, 2003)
"Forty seven patients with IgA glomerulonephritis (GN) were studied."1.27[Clinical, immunological and therapeutic research in mesangial immunoglobulin-A glomerulonephritis]. ( Belovezhdov, N; Robeva, R, 1984)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iitaka, K1
Yamamoto, A1
Ogawa, N1
Sekine, T1
Tamai, S1
Motoyama, O1
Zucchelli, P1
ZuccalĂ , A1
Santoro, A1
Degli Esposti, E1
Sturani, A1
Chiarini, C1
Belovezhdov, N1
Robeva, R1
Kobayashi, Y1
Hiki, Y1
Kokubo, T1
Horii, A1
Tateno, S1
Perico, N1
Remuzzi, A1
Sangalli, F1
Azzollini, N1
Mister, M1
Ruggenenti, P1
Remuzzi, G1

Trials

2 trials available for indomethacin and Glomerulonephritis, IGA

ArticleYear
Steroid therapy during the early stage of progressive IgA nephropathy. A 10-year follow-up study.
    Nephron, 1996, Volume: 72, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dipyridamole; Disease Prog

1996
The antiproteinuric effect of angiotensin antagonism in human IgA nephropathy is potentiated by indomethacin.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:12

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflam

1998

Other Studies

3 other studies available for indomethacin and Glomerulonephritis, IGA

ArticleYear
IgA-associated glomerulonephritis with membranoproliferative glomerulonephritis-like pattern in two children.
    Clinical and experimental nephrology, 2003, Volume: 7, Issue:4

    Topics: Anti-Inflammatory Agents; Biopsy; Cell Division; Child; Child, Preschool; Female; Glomerular Mesangi

2003
Characteristics of hypertension in primary IgA glomerulonephritis.
    Contributions to nephrology, 1984, Volume: 40

    Topics: Adolescent; Adult; Aldosterone; Child; Female; Glomerulonephritis, IGA; Humans; Hypertension; Indome

1984
[Clinical, immunological and therapeutic research in mesangial immunoglobulin-A glomerulonephritis].
    Vutreshni bolesti, 1984, Volume: 23, Issue:6

    Topics: Acenocoumarol; Adolescent; Adult; Antigen-Antibody Complex; Azathioprine; Chronic Disease; Complemen

1984