indomethacin has been researched along with Glaucoma in 18 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Regarding superficial punctate keratitis, the corneal tolerance of preservative-free indomethacin 0." | 9.10 | Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs. ( Allaire, C; Baudouin, C; Creuzot-Garcher, C; Denis, P; Nordmann, JP; Trinquand, C, 2002) |
| "When indomethacin treatment was discontinued in those patients receiving topical epinephrine, there was a further significant (P less than ." | 6.66 | Inhibition of the epinephrine-induced reduction of intraocular pressure by systemic indomethacin in humans. ( Camras, CB; Christensen, RE; Fazio, DT; Feldman, SG; Gardner, SK; Podos, SM, 1985) |
| " Regarding superficial punctate keratitis, the corneal tolerance of preservative-free indomethacin 0." | 5.10 | Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs. ( Allaire, C; Baudouin, C; Creuzot-Garcher, C; Denis, P; Nordmann, JP; Trinquand, C, 2002) |
| "The authors submit results of the clinical investigation involving indomethacin administration during preoperative and postoperative care of patients with primary glaucoma who were submitted to trabeculectomy." | 5.06 | [Prostanoids and leukotrienes in ophthalmology. III. Results of a clinical study of local administration of indomethacin in preoperative and postoperative care]. ( Havlícek, K; Macek, K; Rehák, S, 1990) |
| "Seventy glaucomatous eyes received argon laser trabeculoplasty (ALT) to 180 degrees of the trabecular meshwork." | 5.05 | Nonsteroidal anti-inflammatory agents after argon laser trabeculoplasty. A trial with flurbiprofen and indomethacin. ( Hotchkiss, ML; Pollack, IP; Quigley, HA; Robin, AL, 1984) |
| "When indomethacin treatment was discontinued in those patients receiving topical epinephrine, there was a further significant (P less than ." | 2.66 | Inhibition of the epinephrine-induced reduction of intraocular pressure by systemic indomethacin in humans. ( Camras, CB; Christensen, RE; Fazio, DT; Feldman, SG; Gardner, SK; Podos, SM, 1985) |
| "Pretreatment with indomethacin did not block the intraocular pressure rise induced by A23187." | 1.26 | The effect of cation ionophores on intraocular pressure. ( Podos, SM, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (77.78) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armstrong, JJ | 1 |
| Denstedt, JT | 1 |
| Trelford, CB | 1 |
| Li, EA | 1 |
| Hutnik, CML | 1 |
| Baudouin, C | 1 |
| Nordmann, JP | 1 |
| Denis, P | 1 |
| Creuzot-Garcher, C | 1 |
| Allaire, C | 1 |
| Trinquand, C | 1 |
| Hotchkiss, ML | 1 |
| Robin, AL | 1 |
| Pollack, IP | 1 |
| Quigley, HA | 1 |
| March, WF | 1 |
| Gherezghiher, T | 1 |
| Koss, M | 1 |
| Nordquist, R | 1 |
| Migdal, C | 1 |
| Hitchings, R | 1 |
| Waitzman, MB | 1 |
| Singh, R | 1 |
| Rao, MC | 1 |
| Bhatatcharya, SK | 1 |
| Gandolfi, SA | 1 |
| Vecchi, M | 1 |
| Braccio, L | 1 |
| Podos, SM | 3 |
| Havlícek, K | 1 |
| Macek, K | 1 |
| Rehák, S | 1 |
| Camras, CB | 2 |
| Gabel, VP | 1 |
| Kozma, M | 1 |
| Zink, H | 1 |
| Birngruber, R | 1 |
| Tuulonen, A | 1 |
| Feldman, SG | 1 |
| Christensen, RE | 1 |
| Gardner, SK | 1 |
| Fazio, DT | 1 |
| Henkind, P | 1 |
| Gold, DH | 1 |
| Sears, D | 1 |
| Sears, M | 1 |
| Béchetoille, A | 1 |
| Lepêtre, C | 1 |
| Guillaumat, L | 1 |
| Deutsch, AR | 1 |
| Hiatt, RL | 1 |
2 reviews available for indomethacin and Glaucoma
| Article | Year |
|---|---|
The role of endogenous prostaglandins in clinically-used and investigational glaucoma therapy.
Topics: Animals; Cyclooxygenase Inhibitors; Flurbiprofen; Glaucoma; Humans; Indomethacin; Intraocular Pressu | 1989 |
Ocular manifestations of rheumatic disorders. Natural and iatrogenic.
Topics: Adrenal Cortex Hormones; Arteritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Chloroquine; Conjunc | 1973 |
7 trials available for indomethacin and Glaucoma
| Article | Year |
|---|---|
Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Conjunctiv | 2002 |
Nonsteroidal anti-inflammatory agents after argon laser trabeculoplasty. A trial with flurbiprofen and indomethacin.
Topics: Adult; Aged; Argon; Clinical Trials as Topic; Double-Blind Method; Eye Diseases; Female; Flurbiprofe | 1984 |
Effect of antiprostaglandins on glaucoma filtration surgery.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Glaucoma; Humans; Indomethacin; Intraocu | 1982 |
Decrease of intraocular pressure after subconjunctival injection of mitomycin in human glaucoma.
Topics: Adult; Aged; Aqueous Humor; Blindness; Conjunctiva; Female; Glaucoma; Humans; Indomethacin; Injectio | 1995 |
[Prostanoids and leukotrienes in ophthalmology. III. Results of a clinical study of local administration of indomethacin in preoperative and postoperative care].
Topics: Double-Blind Method; Glaucoma; Humans; Indomethacin; Middle Aged; Ophthalmic Solutions; Postoperativ | 1990 |
The effect of topical indomethacin on acute pressure elevation of laser trabeculoplasty in capsular glaucoma.
Topics: Aged; Clinical Trials as Topic; Female; Glaucoma; Humans; Indomethacin; Intraocular Pressure; Laser | 1985 |
Inhibition of the epinephrine-induced reduction of intraocular pressure by systemic indomethacin in humans.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Clinical Trials as Topic; Double-Blind M | 1985 |
9 other studies available for indomethacin and Glaucoma
| Article | Year |
|---|---|
Differential effects of dexamethasone and indomethacin on Tenon's capsule fibroblasts: Implications for glaucoma surgery.
Topics: Anti-Inflammatory Agents; Collagen; Dexamethasone; Fibroblasts; Glaucoma; Humans; Indomethacin; Teno | 2019 |
Ultrastructural and pharmacologic studies on laser-induced glaucoma in primates and rabbits.
Topics: Animals; Disease Models, Animal; Epinephrine; Glaucoma; Indomethacin; Intraocular Pressure; Lasers; | 1984 |
Prostaglandins and the eye: rapid transition from basic to applied and implications for expanded clinical consideration.
Topics: Animals; Diabetic Retinopathy; Dogs; Edema; Eye Diseases; Glaucoma; Humans; Indomethacin; Norepineph | 1982 |
Plasma prostaglandin in primary glaucoma.
Topics: Adult; Aged; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Indomethacin; Male; Middle Aged; Prosta | 1982 |
The effect of cation ionophores on intraocular pressure.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aqueous Humor; Calcimycin; Dose-Response | 1976 |
[Behavior of postoperative intraocular pressure following iridectomy and capsulotomy using a neodymium:YAG laser with reference to the effect of indomethacin].
Topics: Cataract Extraction; Glaucoma; Humans; Indomethacin; Intraocular Pressure; Iris; Laser Therapy; Ocul | 1987 |
Blood-aqueous barrier and alpha-chymotrypsin glaucoma in rabbits.
Topics: Animals; Aqueous Humor; Biological Transport; Blood; Chymotrypsin; Drug Antagonism; Glaucoma; Indome | 1974 |
[Action of indomethacin on ocular pressure. Preliminary study].
Topics: Animals; Cats; Glaucoma; Humans; Indomethacin; Intraocular Pressure; Placebos; Prostaglandins; Rabbi | 1971 |
Effects of indomethacin on intraocular dynamics.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Glaucoma; Humans; Indomethacin; Intraocular Pressure; Ma | 1969 |