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indomethacin and Glaucoma, Suspect

indomethacin has been researched along with Glaucoma, Suspect in 11 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"The onset of ocular hypertension occurred within 15 min."5.28Argon laser-induced ocular hypertension: animal model of ocular inflammation. ( Gherezghiher, T; Koss, MC, 1989)
"A loss of the significance of intraocular pressure reduction with brimonidine was noted after oral indomethacin coadministration (-14%; P =."5.10Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy. ( McKinnon, S; Paris, G; Pena, M; Sanford, K; Sponsel, WE; Trigo, Y; Weber, A, 2002)
"To investigate the time course of changes in optic nerve head (ONH) circulation after an acute increase in intraocular pressure (IOP), by using the laser speckle method, and to evaluate the effects of a calcium antagonist, the nitric oxide synthetase inhibitor, indomethacin, or sympathetic nerve amputation on the response in ONH circulation after an acute increase in IOP."3.72Time course of the change in optic nerve head circulation after an acute increase in intraocular pressure. ( Araie, M; Fukaya, Y; Hosokawa, T; Ishii, K; Takayama, J; Tamaki, Y; Tomidokoro, A, 2003)
"Topical use of Indomethacin was documented to prevent surgically induced miosis, and it reduced postoperative inflammatory response."3.68The effect of 0.1% Indomethacin eyedrops on cataract surgery. ( Liou, SW; Yen, RJ, 1991)
"Intraocular pressure was measured at specific times after exposure."1.29Enhanced prostaglandin synthesis after ultraviolet-B exposure modulates DNA synthesis of lens epithelial cells and lowers intraocular pressure in vivo. ( Andley, UP; Becker, B; Hebert, JS; Morrison, AR; Pentland, AP; Reddan, JR, 1996)
"Pretreatment with indomethacin or pilocarpine specifically attenuated the ability of MK-422 to lower IOP suggesting that biosynthesis of prostaglandins and uveoscleral outflow pathways are important in mediating the ocular hypotension."1.28Prostaglandins mediate the ocular hypotensive action of the angiotensin converting enzyme inhibitor MK-422 (enalaprilat) in African green monkeys. ( Lotti, VJ; Pawlowski, N, 1990)
"The onset of ocular hypertension occurred within 15 min."1.28Argon laser-induced ocular hypertension: animal model of ocular inflammation. ( Gherezghiher, T; Koss, MC, 1989)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's4 (36.36)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takayama, J1
Tomidokoro, A1
Ishii, K1
Tamaki, Y1
Fukaya, Y1
Hosokawa, T1
Araie, M1
Koss, MC2
March, WF1
Nordquist, RE1
Gherezghiher, T2
Peng, DW1
Andley, UP1
Becker, B1
Hebert, JS1
Reddan, JR1
Morrison, AR1
Pentland, AP1
Sponsel, WE1
Paris, G1
Trigo, Y1
Pena, M1
Weber, A1
Sanford, K1
McKinnon, S1
Liou, SW1
Yen, RJ1
Lotti, VJ1
Pawlowski, N1
Pham Duy, T1
Wollensak, J1
Becker, U1
Bondareva, GS1
Gabel, VP1
Kozma, M1
Zink, H1
Birngruber, R1

Reviews

1 review available for indomethacin and Glaucoma, Suspect

ArticleYear
[Use of indomethacin in ophthalmology].
    Oftalmologicheskii zhurnal, 1986, Issue:3

    Topics: Administration, Oral; Animals; Cataract Extraction; Drug Evaluation; Drug Evaluation, Preclinical; E

1986

Trials

3 trials available for indomethacin and Glaucoma, Suspect

ArticleYear
[Prevention of IOP rise following laser iridectomy with topical timolol and indomethacin].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1993, Volume: 29, Issue:2

    Topics: Female; Glaucoma, Angle-Closure; Humans; Indomethacin; Iris; Laser Therapy; Male; Middle Aged; Ocula

1993
Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy.
    American journal of ophthalmology, 2002, Volume: 133, Issue:1

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents;

2002
[Elevation of intraocular pressure following Nd-YAG laser capsulotomy. Pathogenesis and preventive therapy].
    Klinische Monatsblatter fur Augenheilkunde, 1987, Volume: 191, Issue:4

    Topics: Cataract Extraction; Drug Therapy, Combination; Humans; Indomethacin; Intraocular Pressure; Laser Th

1987

Other Studies

7 other studies available for indomethacin and Glaucoma, Suspect

ArticleYear
Time course of the change in optic nerve head circulation after an acute increase in intraocular pressure.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:9

    Topics: Animals; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Indomethacin; Intraocular

2003
Acute intraocular pressure elevation produced by argon laser trabeculoplasty in the cynomolgus monkey.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:11

    Topics: Animals; Disease Models, Animal; Female; Indomethacin; Inflammation; Laser Therapy; Lasers; Macaca f

1984
Enhanced prostaglandin synthesis after ultraviolet-B exposure modulates DNA synthesis of lens epithelial cells and lowers intraocular pressure in vivo.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Autoradiography; Cell Division; Cell Line; Cells, Cultured; Cy

1996
The effect of 0.1% Indomethacin eyedrops on cataract surgery.
    Journal of ocular pharmacology, 1991,Spring, Volume: 7, Issue:1

    Topics: Cataract Extraction; Humans; Indomethacin; Intraocular Pressure; Intraoperative Complications; Miosi

1991
Prostaglandins mediate the ocular hypotensive action of the angiotensin converting enzyme inhibitor MK-422 (enalaprilat) in African green monkeys.
    Journal of ocular pharmacology, 1990,Spring, Volume: 6, Issue:1

    Topics: Administration, Topical; Angiotensin-Converting Enzyme Inhibitors; Animals; Cercopithecus; Chloroceb

1990
Argon laser-induced ocular hypertension: animal model of ocular inflammation.
    Journal of ocular pharmacology, 1989,Spring, Volume: 5, Issue:1

    Topics: Animals; Aqueous Humor; Argon; Disease Models, Animal; Endophthalmitis; Female; Flurbiprofen; Gangli

1989
[Behavior of postoperative intraocular pressure following iridectomy and capsulotomy using a neodymium:YAG laser with reference to the effect of indomethacin].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1987, Volume: 84, Issue:1

    Topics: Cataract Extraction; Glaucoma; Humans; Indomethacin; Intraocular Pressure; Iris; Laser Therapy; Ocul

1987