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indomethacin and Germinoblastoma

indomethacin has been researched along with Germinoblastoma in 26 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to determine if evolution of fever after administration of indomethacin to febrile patients could separate those with fever of infectious origin from those with non-infectious origin."7.69[Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?]. ( Barrier, J; Becq-Giraudon, B; Ramassamy, A; Roblot, P, 1995)
"In one patient with untreated Hodgkin's disease, temperature fell from 40."5.27Antipyretic effect of indomethacin in malignant lymphoma. ( Björkholm, M; Engervall, P; Grimfors, G; Holm, G, 1986)
"When indomethacin was added in vitro, lymphocytes from healthy controls showed similar but more consistent increases of PHA responses than lymphocytes from patients with sarcoidosis or lymphoma."5.27The effect of indomethacin treatment on lymphocyte PHA reactivity in healthy controls and patients with lymphoma and sarcoidosis. ( Underhill, G; Valdimarsson, H, 1985)
"The aim of this study was to determine if evolution of fever after administration of indomethacin to febrile patients could separate those with fever of infectious origin from those with non-infectious origin."3.69[Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?]. ( Barrier, J; Becq-Giraudon, B; Ramassamy, A; Roblot, P, 1995)
"In one patient with untreated Hodgkin's disease, temperature fell from 40."1.27Antipyretic effect of indomethacin in malignant lymphoma. ( Björkholm, M; Engervall, P; Grimfors, G; Holm, G, 1986)
"Treatment with indomethacin results in inhibition of tumor cell growth and elimination of all recoverable tumor cells."1.27Immune regulation of the L5178Y murine tumor-dormant state. I. In vivo and in vitro effects of prostaglandin E2 and indomethacin on tumor cell growth. ( Goldman, P; Liu, CM; Okayasu, T; Suzuki, K; Suzuki, Y; Wheelock, EF, 1986)
"When indomethacin was added in vitro, lymphocytes from healthy controls showed similar but more consistent increases of PHA responses than lymphocytes from patients with sarcoidosis or lymphoma."1.27The effect of indomethacin treatment on lymphocyte PHA reactivity in healthy controls and patients with lymphoma and sarcoidosis. ( Underhill, G; Valdimarsson, H, 1985)
"Third, indomethacin, treatment of fibrosarcoma cultures reduced the amount of supernatant inhibitory substance present."1.26Inhibition of lymphoma cell proliferation by supernatant from fibrosarcoma cultures: preliminary evidence that the inhibitory material is prostaglandin E. ( Sonis, ST; Stelos, P; Stylos, WA; Wilson, RE, 1977)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199021 (80.77)18.7374
1990's4 (15.38)18.2507
2000's1 (3.85)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Keefe, D1
Ashman, L1
Palladino, MA1
Welte, K1
Konaka, Y1
Takiguchi, T1
Konda, S1
Barrier, J1
Roblot, P1
Ramassamy, A1
Becq-Giraudon, B1
Whyte, AL1
Miller, SC1
Papadimitriou, MN1
McIntire, LV1
Menter, DG1
Vosixa, G1
Thies, J1
Sonis, ST1
Stelos, P1
Stylos, WA1
Wilson, RE1
Maca, RD1
Faradzhev, ZG2
Mazina, NM1
Ivshina, AV1
Samsonov, VA1
Bassalyk, LS1
Nemtsova, MP1
Strayer, DS1
Korber, K1
Dombrowski, J1
Bittner, S1
Wielckens, K1
Russell, DH1
Buckley, AR1
Montgomery, DW1
Larson, NA1
Gout, PW1
Beer, CT1
Putnam, CW1
Zukoski, CF1
Kibler, R1
Mizushima, Y1
Morikage, T1
Hirata, H1
Sato, M1
Sakamoto, K1
Yano, S1
Rayhel, EJ1
Prentice, DA1
Tabor, PS1
Flurkey, WH1
Geib, RW1
Laherty, RF1
Schnitzer, SB1
Chen, R1
Hughes, JP1
Engervall, P1
Björkholm, M1
Grimfors, G1
Holm, G1
Liu, CM1
Okayasu, T1
Goldman, P1
Suzuki, Y1
Suzuki, K1
Wheelock, EF1
Farrar, WL1
Humes, JL1
Sébahoun, G1
Maraninchi, D1
Carcassonne, Y1
Underhill, G1
Valdimarsson, H1
Kiely, JM1
Banerjee, AK1
Milevskaia, IuL1
Treske, U1
Marcolongo, R1
Bianco, G1
Di Paolo, N1
Bravi, A1

Other Studies

26 other studies available for indomethacin and Germinoblastoma

ArticleYear
Variation in accessory cell requirements in human mixed lymphocyte response to leukaemic cell lines.
    Immunology, 1982, Volume: 47, Issue:4

    Topics: Adult; Cell Line; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Indomethacin; Leuke

1982
Interleukin regulation of the immune system (IRIS) in male homosexuals with acquired immune deficiency disease syndrome.
    Annals of the New York Academy of Sciences, 1984, Volume: 437

    Topics: Acquired Immunodeficiency Syndrome; Adult; Homosexuality; Humans; In Vitro Techniques; Indomethacin;

1984
[Immunotherapy of malignant lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1983, Volume: 24, Issue:4

    Topics: Animals; Biological Products; Female; Humans; Indomethacin; Lymphocyte Activation; Lymphoma; Mice; M

1983
[Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?].
    La Revue de medecine interne, 1995, Volume: 16, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Body Temperature; Diagnosis, Differential; Female; Fever; Humans; Hy

1995
Strain differences in natural killer cell-mediated immunity among mice: a possible mechanism for the low natural killer cell activity of A/J mice.
    Immunobiology, 1998, Volume: 199, Issue:1

    Topics: Animals; Bone Marrow Cells; Cytotoxicity, Immunologic; Indomethacin; Interleukin-2; Killer Cells, Na

1998
Effect of cyclooxygenase inhibitors in the adhesion of tumor cells to endothelial cells.
    Critical reviews in biomedical engineering, 2000, Volume: 28, Issue:1-2

    Topics: Animals; Cell Adhesion; Cyclooxygenase Inhibitors; Endothelium; Indomethacin; Integrins; Lymphoma; M

2000
Effect of indomethacin on blastogenesis of lymphocytes from cancer patients: differentiation of patient types.
    Clinical immunology and immunopathology, 1979, Volume: 13, Issue:1

    Topics: Humans; Immunity, Cellular; Indomethacin; Leiomyosarcoma; Lung Neoplasms; Lymphocyte Activation; Lym

1979
Inhibition of lymphoma cell proliferation by supernatant from fibrosarcoma cultures: preliminary evidence that the inhibitory material is prostaglandin E.
    Prostaglandins, 1977, Volume: 13, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Chromatography, Thin Layer; Culture Media; Depression, Chem

1977
Enhancement of etoposide and methotrexate sensitivity by indomethacin in vitro.
    Anti-cancer drug design, 1991, Volume: 6, Issue:5

    Topics: Animals; Bleomycin; Drug Synergism; Etoposide; Humans; Indomethacin; Leukemia, Myelogenous, Chronic,

1991
[The effect of therapy on the immunological indices in patients with skin lymphomas and Kaposi's sarcoma].
    Vestnik dermatologii i venerologii, 1990, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Humans; In

1990
[The effectiveness of treating patients with malignant skin lymphoma and Kaposi's sarcoma studied via polyamines].
    Vestnik dermatologii i venerologii, 1989, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Drug Evalu

1989
Immunosuppression during viral oncogenesis. IV. Generation of soluble virus-induced immunologic suppressor molecules.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Mar-15, Volume: 140, Issue:6

    Topics: Animals; Cyclic AMP; Cyclic GMP; Depression, Chemical; DNA Tumor Viruses; Female; Fibroma Virus, Rab

1988
Glucocorticoid-induced lymphoma cell growth inhibition: the role of leukotriene B4.
    Endocrinology, 1988, Volume: 123, Issue:2

    Topics: Animals; Cell Division; Cell Survival; Dexamethasone; Glucocorticoids; Indomethacin; Interphase; Leu

1988
Prolactin-dependent mitogenesis in Nb 2 node lymphoma cells: effects of immunosuppressive cyclopeptides.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Jan-01, Volume: 138, Issue:1

    Topics: Animals; Calcimycin; Cell Division; Cyclosporins; Depsipeptides; DNA; Enzyme Induction; Estradiol; G

1987
Synergistic therapeutic effect of combination therapy with OK-432 and interferon-alpha or -gamma on Meth-A ascites tumor in BALB/c mice.
    Journal of biological response modifiers, 1988, Volume: 7, Issue:4

    Topics: Animals; Biological Products; Cells, Cultured; Combined Modality Therapy; Drug Synergism; Fibrosarco

1988
Inhibition of Nb2 T-lymphoma cell growth by transforming growth factor-beta.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: Animals; Cell Division; Dinoprostone; Growth Hormone; Indomethacin; Interleukin-2; Lymphoma; Peptide

1988
Antipyretic effect of indomethacin in malignant lymphoma.
    Acta medica Scandinavica, 1986, Volume: 219, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Female; Hodgkin Disease; Hum

1986
Immune regulation of the L5178Y murine tumor-dormant state. I. In vivo and in vitro effects of prostaglandin E2 and indomethacin on tumor cell growth.
    The Journal of experimental medicine, 1986, Oct-01, Volume: 164, Issue:4

    Topics: Animals; Cells, Cultured; Dinoprostone; Female; Indomethacin; Lymphoma; Macrophages; Mice; Mice, Inb

1986
The role of arachidonic acid metabolism in the activities of interleukin 1 and 2.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Humans; Hydroxyeicosatetraenoic Acids; Indo

1985
Increased prostaglandin E production in malignant lymphomas.
    Acta haematologica, 1985, Volume: 74, Issue:3

    Topics: Adolescent; Adult; Aged; Bone Marrow; Cells, Cultured; Child; Culture Media; Female; Humans; Indomet

1985
The effect of indomethacin treatment on lymphocyte PHA reactivity in healthy controls and patients with lymphoma and sarcoidosis.
    British journal of haematology, 1985, Volume: 60, Issue:3

    Topics: Adolescent; Adult; Cells, Cultured; Female; Hodgkin Disease; Humans; Indomethacin; Lymphocyte Activa

1985
Symptomatic control of fever in lymphoma and leukemia.
    Mayo Clinic proceedings, 1969, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Aspirin; Female; Fever; Hodgkin Disease; Humans; I

1969
Use of Indomethacin as an anti-pyretic agent in malignant reticulosis.
    The Medical journal of Malaya, 1972, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Child; Evaluation Studies as Topic; Female; Fever; Hodgkin Disease; Humans; Indom

1972
[Use of indomethacin in internal and hematologic practice].
    Terapevticheskii arkhiv, 1970, Volume: 42, Issue:1

    Topics: Hodgkin Disease; Humans; Indomethacin; Joint Diseases; Leukemia; Lymphoma; Lymphoma, Large B-Cell, D

1970
[Indomethacin in hemoblastosis].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:11

    Topics: Hodgkin Disease; Humans; Indomethacin; Joint Diseases; Leukemia; Lymphoma; Lymphoma, Large B-Cell, D

1971
[Clinical research on the antipyretic effects of indomethacin in systemic hemopathies].
    Minerva medica, 1970, Oct-13, Volume: 61, Issue:82

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anemia, Aplastic; Antibiotics, Antineoplastic; Ant

1970