Page last updated: 2024-10-29

indomethacin and Fibromyalgia

indomethacin has been researched along with Fibromyalgia in 8 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
"300 mg/day phenylbutazone, 210 mg/day indomethacin, and 600 mg/day pyrasanone were administered for 14 days to three randomised groups of patients respectively, consisting of a total of 76 subjects with various forms of non-infectious inflammation (osteoarthritis, fibrositis, rheumatoid arthritis, gout, phlebitis), in a double-blind trila designed to determine the activity of the three drugs and their tolerance."5.04[Evaluation of the effects of some non-steroid anti-inflammatory agents on the gastric mucosa]. ( Bianchi, PA; Polli, EE; Vigo, PL, 1976)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KELLY, M2
VECCHIO, C1
MONTEMARTINI, C1
Bianchi, PA1
Vigo, PL1
Polli, EE1
Stambolović, B1
Velimirović, D1
Islam, N1
Rahman, AM1
Rothermich, NO2

Trials

2 trials available for indomethacin and Fibromyalgia

ArticleYear
[Evaluation of the effects of some non-steroid anti-inflammatory agents on the gastric mucosa].
    Minerva medica, 1976, Jul-07, Volume: 67, Issue:33

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Diarrhea; Drug Tolerance; Female; Fibromyalgia; Gas

1976
Indomethacin in extra-articular lesions.
    The British journal of clinical practice, 1970, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Bursitis; Clinical Trials as Topic; Female; Fibromyalgia; Humans; Indomethacin; J

1970

Other Studies

6 other studies available for indomethacin and Fibromyalgia

ArticleYear
INDOMETHACIN, REMARKABLE ANTIRHEUMATIC DRUG.
    The Medical journal of Australia, 1964, Oct-03, Volume: 2

    Topics: Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Fibromyalgia; Geriatrics; Gout

1964
[INDOMETHACIN IN THE TREATMENT OF SOME INFLAMMATORY RHEUMATIC DISEASES].
    La Clinica terapeutica, 1964, Sep-30, Volume: 30

    Topics: Adolescent; Arthritis; Arthritis, Rheumatoid; Biomedical Research; Drug Therapy; Fibromyalgia; Geria

1964
[Diagnosis and treatment of rheumatic disorders in the pelvis].
    Zentralblatt fur Gynakologie, 1974, Aug-09, Volume: 96, Issue:32

    Topics: Antistreptolysin; Blood Sedimentation; Female; Fibromyalgia; Focal Infection; Humans; Indomethacin;

1974
Treatment of 193 rheumatic patients with indomethacin, a new antirheumatic drug.
    Journal of the American Geriatrics Society, 1966, Volume: 14, Issue:1

    Topics: Arthritis, Rheumatoid; Fibromyalgia; Gout; Indomethacin; Stomach Diseases

1966
An extended study of indomethacin. I. Clinical pharmacology.
    JAMA, 1966, Feb-14, Volume: 195, Issue:7

    Topics: Adult; Aged; Arthritis; Central Nervous System Diseases; Fibromyalgia; Gastrointestinal Diseases; He

1966
[5 years of experience with indomethacin].
    La Clinica terapeutica, 1967, Jun-15, Volume: 41, Issue:5

    Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Eye; Female; Fibromyalgia; Gastroint

1967