Page last updated: 2024-10-29

indomethacin and Fetal Growth Restriction

indomethacin has been researched along with Fetal Growth Restriction in 8 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"of indomethacin was associated with closure of PDA in 108 (77."5.35Factors affecting successful closure of hemodynamically significant patent ductus arteriosus with indomethacin in extremely low birth weight infants. ( Lee, J; Yang, CZ, 2008)
"Indomethacin was used for median (IQR) 3 (2-5) days while ibuprofen was given for 3 (2-4) days, at a median of 8 and 10 days after birth, respectively; surgical treatment was used later at 33 (24-45) days after birth."1.72Management of patent ductus arteriosus in very preterm infants in England and Wales: a retrospective cohort study. ( Al-Turkait, A; Choonara, I; Ojha, S; Szatkowski, L, 2022)
"Pregnancy in patients with chronic renal failure occurs rarely but the incidence is increasing."1.37Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report. ( Baykal, C; Kaya, S; Takal, MK; Yakupoğlu, U, 2011)
"of indomethacin was associated with closure of PDA in 108 (77."1.35Factors affecting successful closure of hemodynamically significant patent ductus arteriosus with indomethacin in extremely low birth weight infants. ( Lee, J; Yang, CZ, 2008)
"The chronic use of prostaglandin synthetase inhibitors is reported in a pregnant patient with severe juvenile rheumatoid arthritis."1.26Oligohydramnios and transient neonatal anuria: a possible association with the maternal use of prostaglandin synthetase inhibitors. ( Cantor, B; Nelson, RM; Stein, GH; Tyler, T, 1980)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Al-Turkait, A1
Szatkowski, L1
Choonara, I1
Ojha, S1
Villamor, E1
Borges-Luján, M1
González-Luis, G1
Shanahan, KH1
Yu, X1
Miller, LG1
Freedman, SD1
Martin, CR1
Yang, CZ1
Lee, J1
Baykal, C1
Kaya, S1
Takal, MK1
Yakupoğlu, U1
Barreto, RR1
Franco, Ede S1
Brasileiro, CF1
de Oliveira, AP1
Dimech, GS1
Malta, DJ1
Cazuzu, JS1
Leite, AC1
da Silva, TG1
Maia, MB1
Cantor, B1
Tyler, T1
Nelson, RM1
Stein, GH1
Tsuruta, K1
Mori, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Drug Utilization Patterns in Neonatal Units in the UK: a Retrospective Pharmaco-epidemiological Study[NCT03773289]642,729 participants (Actual)Observational2018-04-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for indomethacin and Fetal Growth Restriction

ArticleYear
Association of patent ductus arteriosus with fetal factors and endotypes of prematurity.
    Seminars in perinatology, 2023, Volume: 47, Issue:2

    Topics: Ductus Arteriosus, Patent; Female; Fetal Growth Retardation; Humans; Ibuprofen; Indomethacin; Infant

2023

Other Studies

7 other studies available for indomethacin and Fetal Growth Restriction

ArticleYear
Management of patent ductus arteriosus in very preterm infants in England and Wales: a retrospective cohort study.
    BMJ paediatrics open, 2022, Volume: 6, Issue:1

    Topics: Ductus Arteriosus, Patent; Female; Fetal Growth Retardation; Humans; Ibuprofen; Indomethacin; Infant

2022
Early Serum Gut Hormone Concentrations Associated With Time to Full Enteral Feedings in Preterm Infants.
    Journal of pediatric gastroenterology and nutrition, 2018, Volume: 67, Issue:1

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Enteral Nutrition; Female; Fetal Growth Retardatio

2018
Factors affecting successful closure of hemodynamically significant patent ductus arteriosus with indomethacin in extremely low birth weight infants.
    World journal of pediatrics : WJP, 2008, Volume: 4, Issue:2

    Topics: Birth Weight; Causality; Cohort Studies; Ductus Arteriosus, Patent; Female; Fetal Growth Retardation

2008
Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report.
    Clinical and experimental obstetrics & gynecology, 2011, Volume: 38, Issue:1

    Topics: Abortion, Habitual; Adult; Amniotic Fluid; Betamethasone; Birth Weight; Female; Fetal Growth Retarda

2011
Early undernutrition is associated with attenuated inflammatory response and alteration in pharmacological efficacy of indomethacin in rats.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, May-12, Volume: 46, Issue:1-2

    Topics: Analysis of Variance; Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; C

2012
Oligohydramnios and transient neonatal anuria: a possible association with the maternal use of prostaglandin synthetase inhibitors.
    The Journal of reproductive medicine, 1980, Volume: 24, Issue:5

    Topics: Adult; Anuria; Arthritis, Juvenile; Blood Urea Nitrogen; Creatinine; Cyclooxygenase Inhibitors; Fema

1980
[Experimental intrauterine growth retardation with indomethacin].
    Nihon Sanka Fujinka Gakkai zasshi, 1986, Volume: 38, Issue:1

    Topics: Animals; Body Weight; Cyclooxygenase Inhibitors; Fasting; Female; Fetal Growth Retardation; Gestatio

1986