Page last updated: 2024-10-29

indomethacin and Eye Burns

indomethacin has been researched along with Eye Burns in 8 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Eye Burns: Injury to any part of the eye by extreme heat, chemical agents, or ultraviolet radiation.

Research Excerpts

ExcerptRelevanceReference
"In this study, we aimed to investigate the effect of indomethacin and dimethyl sulfoxide (DMSO), well-known antioxidant and anti-inflammatory agents, to heal eye burns induced with hydrofluoric acid in rabbits."7.85Dimethyl sulfoxide but not indomethacin is efficient for healing in hydrofluoric acid eye burns. ( Altan, S; Oğurtan, Z, 2017)
"In this study, we aimed to investigate the effect of indomethacin and dimethyl sulfoxide (DMSO), well-known antioxidant and anti-inflammatory agents, to heal eye burns induced with hydrofluoric acid in rabbits."3.85Dimethyl sulfoxide but not indomethacin is efficient for healing in hydrofluoric acid eye burns. ( Altan, S; Oğurtan, Z, 2017)
"Following application of 50 microliter of 2N hydrochloric acid to the rabbit cornea, the intraocular pressure rapidly increases and remains markedly elevated for up to 3 hr."3.66The ocular hypertensive response following experimental acid burns in the rabbit eye. ( Eakins, KE; Ishikawa, R; Jenkins, RM; Paterson, CA; Paterson, E, 1979)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altan, S1
Oğurtan, Z1
Halim Mohamed, MA1
Mahmoud, AA1
Reim, M1
von Kiether, R1
Oglodek, C1
Schaffelt, F1
Thüne, G1
Laria, C1
Alió, JL1
Ruiz-Moreno, JM1
Paterson, CA1
Eakins, KE1
Paterson, E1
Jenkins, RM1
Ishikawa, R1
Deutsch, TA1
Hughes, WF1
Struck, HG1
Franke, C1
Tost, M1
Taube, C1
Schwartzkopff, T1
Pahlitzsch, T1

Trials

1 trial available for indomethacin and Eye Burns

ArticleYear
[Animal experiment and clinical studies of the use of anti-inflammatory agents in chemical burns of the eye].
    Klinische Monatsblatter fur Augenheilkunde, 1988, Volume: 193, Issue:4

    Topics: Animals; Burns, Chemical; Corneal Ulcer; Dexamethasone; Eye Burns; Female; Humans; Indomethacin; Mal

1988

Other Studies

7 other studies available for indomethacin and Eye Burns

ArticleYear
Dimethyl sulfoxide but not indomethacin is efficient for healing in hydrofluoric acid eye burns.
    Burns : journal of the International Society for Burn Injuries, 2017, Volume: 43, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Burns, Chemical; Dimethyl Sulfoxide;

2017
Formulation of indomethacin eye drops via complexation with cyclodextrins.
    Current eye research, 2011, Volume: 36, Issue:3

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextr

2011
[Effect of inhibitors of prostaglandin synthesis on the eye].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1983, Volume: 80, Issue:2

    Topics: Animals; Burns, Chemical; Diclofenac; Eye; Eye Burns; Eye Diseases; Humans; Indomethacin; Inflammati

1983
Combined non-steroidal therapy in experimental corneal injury.
    Ophthalmic research, 1997, Volume: 29, Issue:3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns, Chemical; Cornea;

1997
The ocular hypertensive response following experimental acid burns in the rabbit eye.
    Investigative ophthalmology & visual science, 1979, Volume: 18, Issue:1

    Topics: Animals; Aqueous Humor; Burns, Chemical; Eye Burns; Eye Proteins; Hydrochloric Acid; Hydrogen-Ion Co

1979
Suppressive effects of indomethacin on thermally induced neovascularization of rabbit corneas.
    American journal of ophthalmology, 1979, Volume: 87, Issue:4

    Topics: Animals; Capillaries; Cornea; Eye Burns; Hyperemia; Indomethacin; Prostaglandin Antagonists; Rabbits

1979
[Inhibition of corneal wound healing by locally administered indomethacin].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1987, Volume: 84, Issue:2

    Topics: Animals; Burns, Chemical; Cornea; Corneal Injuries; Eye Burns; Guinea Pigs; Indomethacin; Ophthalmic

1987