indomethacin has been researched along with Extravasation of Contrast Media in 13 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Corneal neovascularization was induced by alkaline cautery in Sprague-Dawley rats and measured after four days." | 1.32 | Effect of COX inhibitors on VEGF-induced retinal vascular leakage and experimental corneal and choroidal neovascularization. ( Castro, MR; Edelman, JL; Lutz, D, 2004) |
| "Pretreatment with indomethacin 1 mg/kg i." | 1.28 | Indomethacin and acetylsalicylic acid block neurogenic plasma protein extravasation in rat dura mater. ( Buzzi, MG; Moskowitz, MA; Sakas, DE, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castro, MR | 1 |
| Lutz, D | 1 |
| Edelman, JL | 1 |
| Björk, J | 1 |
| Smedegård, G | 1 |
| Györfi, A | 1 |
| Fazekas, A | 1 |
| Irmes, F | 1 |
| Rosivall, L | 1 |
| de Lima, WT | 1 |
| Kwasniewski, FH | 1 |
| Sirois, P | 1 |
| Jancar, S | 1 |
| Ueno, A | 1 |
| Tokumasu, T | 1 |
| Naraba, H | 1 |
| Oh-ishi, S | 1 |
| Karádi, O | 1 |
| Abdel-Salam, OM | 1 |
| Bódis, B | 1 |
| Mózsik, G | 1 |
| Fujii, E | 2 |
| Irie, K | 1 |
| Ohba, K | 1 |
| Ogawa, A | 1 |
| Yoshioka, T | 2 |
| Yamakawa, M | 1 |
| Muraki, T | 2 |
| Nakano, M | 1 |
| Matsui, H | 1 |
| Miaki, K | 1 |
| Tsuji, H | 1 |
| Wada, K | 1 |
| Ishida, H | 1 |
| Limbruno, U | 1 |
| Petronio, AS | 1 |
| Amoroso, G | 1 |
| Baglini, R | 1 |
| Paterni, G | 1 |
| Merelli, A | 1 |
| Mariotti, R | 1 |
| Mariani, M | 1 |
| Muller, A | 1 |
| Meynier, F | 1 |
| Bonne, C | 1 |
| Buzzi, MG | 1 |
| Sakas, DE | 1 |
| Moskowitz, MA | 1 |
| Griswold, DE | 1 |
| Webb, EF | 1 |
| Clark, MA | 1 |
| Mong, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging[NCT00857792] | 120 participants (Actual) | Interventional | 2009-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00857792)
Timeframe: 3 months
| Intervention | % accurately detected perfusion defects (Number) |
|---|---|
| Open Label | 78 |
13 other studies available for indomethacin and Extravasation of Contrast Media
| Article | Year |
|---|---|
Effect of COX inhibitors on VEGF-induced retinal vascular leakage and experimental corneal and choroidal neovascularization.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Retinal Barrier; Choroidal Neovascularizatio | 2004 |
Acute microvascular effects of PAF-acether, as studied by intravital microscopy.
Topics: Animals; Cheek; Cricetinae; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Inj | 1983 |
Effect of substance P administration on vascular permeability in the rat oral mucosa and sublingual gland.
Topics: Analysis of Variance; Animals; Capillary Permeability; Carotid Arteries; Cyclooxygenase Inhibitors; | 1995 |
Studies on the mechanism of PAF-induced vasopermeability in rat lungs.
Topics: Animals; Blood Proteins; Bronchi; Capillary Permeability; Evans Blue; Extravasation of Diagnostic an | 1995 |
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capil | 1996 |
Preventive effect of atropine on indomethacin-induced gastrointestinal mucosal and vascular damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Capillary Permeability; Colon; Dose-Resp | 1996 |
Role of nitric oxide, prostaglandins and tyrosine kinase in vascular endothelial growth factor-induced increase in vascular permeability in mouse skin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cycloheximide; Dinoproston | 1997 |
Postlaminectomy adhesion of the cauda equina. Inhibitory effects of anti-inflammatory drugs on cauda equina adhesion in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachnoiditis; Cauda Equ | 1998 |
Role of endogenous nitric oxide in the nitric oxide donor-induced plasma extravasation of mouse skin.
Topics: Animals; Capillary Permeability; Coloring Agents; Dose-Response Relationship, Drug; Drug Interaction | 1999 |
The impact of coronary artery disease on the coronary vasomotor response to nonionic contrast media.
Topics: Aged; Cardiovascular Agents; Contrast Media; Coronary Angiography; Coronary Circulation; Coronary Di | 2000 |
PAF-induced conjunctivitis in the rabbit is mediated by peptido-leukotrienes.
Topics: Animals; Azepines; Conjunctiva; Conjunctivitis; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Evans | 1990 |
Indomethacin and acetylsalicylic acid block neurogenic plasma protein extravasation in rat dura mater.
Topics: Animals; Aspirin; Blood Proteins; Dexamethasone; Dinoprostone; Dura Mater; Electric Stimulation; Ext | 1989 |
Phlogistic activity of leukotriene D4 in the mouse.
Topics: Animals; Capillary Permeability; Dose-Response Relationship, Drug; Edema; Extravasation of Diagnosti | 1986 |