Page last updated: 2024-10-29

indomethacin and Erythema

indomethacin has been researched along with Erythema in 89 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
" In this study we evaluated an assumptive anti-inflammatory effect of the nonsedative histamine H1-receptor antagonist, mizolastine, on UV-induced acute sunburn reaction."9.09UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin. ( Böckelmann, R; Bonnekoh, B; Gollnick, HP; Grundmann, JU, 2001)
"Indomethacin inhibits UVB erythema but is thought not to influence UVA erythema."9.08The effect of topical indomethacin on ultraviolet-radiation-induced erythema. ( Diffey, BL; Farr, PM; Ibbotson, SH, 1996)
"The effect of topical indomethacin on the intensity of UVB- and UVA-induced erythema was measured by reflectance spectrophotometry in 23 patients with polymorphic light eruption."7.67Effect of indomethacin on UVB- and UVA-induced erythema in polymorphic light eruption. ( Diffey, BL; Farr, PM, 1989)
"The effect of indomethacin gel on UVB and UVC erythema was assessed objectively using a reflectance instrument."7.67A quantitative study of the effect of topical indomethacin on cutaneous erythema induced by UVB and UVC radiation. ( Diffey, BL; Farr, PM, 1986)
"The topical effects of N0164 (a phenyl phosphonate derivative which is a partially selective antagonist of prostagladin E2), indomethacin and triamcinolone acetonide have been shown to reduce the erythema and ear weight gain from inflammation induced by experimental contact allergic eczema."7.65Anti-inflammatory properties of a prostaglandin antagonist, a corticosteroid and indomethacin in experimental contact dermatitis. ( Lowe, NJ; Stoughton, RB; Virgadamo, F, 1977)
" In this study we evaluated an assumptive anti-inflammatory effect of the nonsedative histamine H1-receptor antagonist, mizolastine, on UV-induced acute sunburn reaction."5.09UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin. ( Böckelmann, R; Bonnekoh, B; Gollnick, HP; Grundmann, JU, 2001)
"The effects of topical indomethacin and clobetasol propionate on erythema and oedema following low-dose cryotherapy to normal skin were examined using a single-blind technique."5.08The effects of topical indomethacin and clobetasol propionate on post-cryotherapy inflammation. ( Humphreys, F; Spiro, J, 1995)
"When the potent chemoattractant leukotriene B4 (LTB4) is applied topically to human skin it causes delayed onset, long-lasting leukocyte accumulation and erythema."5.08Prolonged microvascular vasodilation induced by leukotriene B4 in human skin is cyclooxygenase independent. ( Fraser, L; Larkin, SW; Showell, HJ; Warren, JB; Williams, TJ, 1995)
"Indomethacin inhibits UVB erythema but is thought not to influence UVA erythema."5.08The effect of topical indomethacin on ultraviolet-radiation-induced erythema. ( Diffey, BL; Farr, PM; Ibbotson, SH, 1996)
" Effects of topical indomethacin (1%) and hydrocortisone (1%) applied before and during radiotherapy were compared for erythema induced by 20 Gy in four fractions (n = 26, 6 MV)."5.08Do inflammatory processes contribute to radiation induced erythema observed in the skin of humans? ( Back, M; Denham, J; Ferguson, S; Hamilton, C; O'Brien, M; O'Brien, P; Ostwald, P; Simonen, P, 1998)
"The relative topical efficacy of indomethacin and diflumidone, a novel non-steroidal antiinflammatory drug, for the suppression of ultraviolet-light (290-320 nm region; UVB)-induced erythema has been compared in a randomized, double-blind, placebo-controlled study in man."5.05Effect of topical diflumidone on ultraviolet-light-induced erythema. ( Gomez, EC; Trancik, RJ, 1981)
"The mechanism of topically applied methyl nicotinate-induced local cutaneous erythema was studied in normal human subjects."5.05Prostaglandins and nicotinate-provoked increase in cutaneous blood flow. ( Flowers, OV; Fortner, G; Kilpatrick, SJ; Reinhardt, LA; Streeter, WC; Wilkin, JK, 1985)
"Topical indomethacin has been reported to inhibit ultraviolet light-induced erythema."3.71Evaluation of the inhibitory activity of topical indomethacin, betamethasone valerate and emollients on UVL-induced inflammation by means of non-invasive measurements of the skin elasticity. ( Dobrev, H, 2001)
"Ultraviolet-B-induced erythema (one, two, or four times the minimal erythema dose) was reduced but not abolished by application of 1% indomethacin gel immediately after irradiation of human skin."3.71Ultraviolet-B-induced erythema is mediated by nitric oxide and prostaglandin E2 in combination. ( Belgi, G; Clough, GF; Friedmann, PS; McLoughlin, L; Parslew, R; Rhodes, LE, 2001)
"Orally administered indomethacin at 10-600 micrograms per mouse per day has been shown to inhibit UV radiation-induced erythema dose responsively."3.69The protective effect of indomethacin on photocarcinogenesis in hairless mice. ( Boehm-Wilcox, C; Bosnic, M; Matheson, MJ; Reeve, VE, 1995)
"The photoprotective and antierythematous effects of topical corticosteroids, acetylsalicylic acid (ASA), indomethacin (IM), butylhydroxytoluene (BHT) and diphenhydramine hydrochloride (DPH) and the influence of the application time on the formation of erythema were studied in healthy volunteers."3.67UVB erythema inhibited by topically applied substances. ( Hannuksela, M; Väänänen, A, 1989)
"The effect of topical indomethacin on the intensity of UVB- and UVA-induced erythema was measured by reflectance spectrophotometry in 23 patients with polymorphic light eruption."3.67Effect of indomethacin on UVB- and UVA-induced erythema in polymorphic light eruption. ( Diffey, BL; Farr, PM, 1989)
"The effect of topical clobetasol propionate and a 1% topical indomethacin gel which could inhibit UV erythema was measured on anthralin inflammation by change in skin-fold thickness and erythema."3.67Mechanism of anthralin inflammation. I. Dissociation of response to clobetasol and indomethacin. ( Lawrence, CM; Shuster, S, 1985)
" The topical application of NSAID ointment (1% of indomethacin, ketoprofen or diclofenac sodium) markedly inhibited the paw edema by carrageenin in rats."3.66[Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs]. ( Kyuki, K, 1982)
"Flumizole is a potent anti-inflammatory agent in animal models with an inhibitory activity severalfold that of indomethacin in rat foot edema and prostaglandin synthetase tests."3.65Flumizole, a new nonsteroidal anti-inflammatory agent. ( Bettis, JW; McIlhenny, HM; Wiseman, EH, 1975)
"The topical effects of N0164 (a phenyl phosphonate derivative which is a partially selective antagonist of prostagladin E2), indomethacin and triamcinolone acetonide have been shown to reduce the erythema and ear weight gain from inflammation induced by experimental contact allergic eczema."3.65Anti-inflammatory properties of a prostaglandin antagonist, a corticosteroid and indomethacin in experimental contact dermatitis. ( Lowe, NJ; Stoughton, RB; Virgadamo, F, 1977)
"5 per cent indomethacin (IM) solution to the sunburned skin of humans and guinea pigs resulted in a marked decrease in ultraviolet light (UVL) -induced erythema."3.65Cutaneous effects of topical indomethacin, an inhibitor of prostaglandin synthesis, on UV-damaged skin. ( Snyder, DS, 1975)
" The results from tape stripping technique confirmed the trend obtained by the former in vivo method and indicated that IND topical bioavailability in the stratum corneum varied substantially depending upon the formulations (A-D)."2.71Evaluation of indomethacin percutaneous absorption from nanostructured lipid carriers (NLC): in vitro and in vivo studies. ( Bonina, F; Di Giovanni, C; Giovagnoli, S; Puglia, C; Ricci, M; Rossi, C, 2005)
"Indomethacin treatment inhibited the flare reactions induced by histamine and compound 48/80 to about 50%, whereas no influence was seen on the itch responses."2.66Separate effects of topical indomethacin on the itch response and on the flare reaction induced by histamine in human skin. ( Hägermark, O; Ståhle, M, 1985)
" We may conclude that this model is adequate and precise for selecting the most appropriate galenic dosage form for an active compound in terms of its clinical efficacy when topically administered."2.66UV-induced erythema model: a tool in dermatopharmacology for testing the topical activity of non-steroidal anti-inflammatory agents in man. ( Barbanoj, MJ; Izquierdo, I; Jané, F; Lauroba, J; Moreno, J; Torrent, J, 1988)
"The red ear syndrome is a rare syndrome originally described by Lance in 1994."2.44Red ear syndrome. ( Dodick, DW; Purdy, RA, 2007)
"Indomethacin did not suppress acceleration of repopulation."1.30Modulation of accelerated repopulation in mouse skin during daily irradiation. ( Heasman, F; Shirazi, A; Trott, KR, 1999)
" Thus, CP-331 exerted anti-inflammatory, analgesic, and antipyretic effects but without showing gastric toxicity, which is a common side effect of anti-inflammatory drugs."1.28Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate. ( Abe, T; Itokazu, Y; Ohya, O; Omata, T; Segawa, Y; Tagashira, E; Tsuzuike, N; Ueda, I; Yoshida, K, 1992)
"Anthralin and UVB were then applied to the gel-treated skin and the anthralin- and UVB-induced erythema and oedema were measured at 2, 6, 24 and 48 h using Harpenden callipers and a reflectance erythrometer."1.28The effect of indomethacin on anthralin inflammation. ( Lawrence, C; Ramsay, B; Rice, N, 1992)
"Indomethacin was only partly successful as an antagonist since 10% inhibition of 12-DOPPA and no inhibition of 12-DOPPAA induced erythema was produced four hours after application."1.26Inhibition of erythema induced by pro-inflammatory esters of 12-deoxyphorbol. ( Evans, FJ; Williamson, EM, 1981)
"TAI-284 protected rabbits from sudden death caused by intravenous injection of arachidonic acid, but the activity was about one twentieth less than that of indomethacin."1.26[Anti-inflammatory property of 6-chloro-5-cyclohexyl-1-indancarboxylic acid (TAI-284) (author's transl)]. ( Fujimura, H; Kyuki, K; Nozaki, M; Tsurumi, K, 1977)
" The very shallow dose-response curves for flurbiprofen compared with acetylsalicylic acid, especially in the mouse and the rat test systems, are not due to an unreliable or abnormal absorption, which suggests that in these species the mode of action of flurbiprofen is not identical with that of acetylsalicylic acid."1.25Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent. ( Adams, SS; McCullough, KF; Nicholson, JS, 1975)

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199060 (67.42)18.7374
1990's16 (17.98)18.2507
2000's10 (11.24)29.6817
2010's2 (2.25)24.3611
2020's1 (1.12)2.80

Authors

AuthorsStudies
Ridge, DN1
Hanifin, JW1
Harten, LA1
Johnson, BD1
Menschik, J1
Nicolau, G1
Sloboda, AE1
Watts, DE1
Kaltenbronn, JS1
Nagai, Y1
Irie, A1
Nakamura, H1
Hino, K1
Uno, H1
Nishimura, H1
Sloan, B1
Chan, TLH1
Becker, WJ1
Jog, M1
Brooke, RC1
Sidhu, M1
Sinha, A1
Watson, RE1
Friedmann, PS2
Clough, GF2
Rhodes, LE2
Suzuki, A1
Yamaguchi, T1
Kawasaki, K1
Hase, T1
Tokimitsu, I1
Puglia, C3
Trombetta, D1
Venuti, V1
Saija, A1
Bonina, F3
Ricci, M1
Di Giovanni, C1
Giovagnoli, S1
Rossi, C1
Esposito, E1
Cortesi, R1
Drechsler, M1
Paccamiccio, L1
Mariani, P1
Contado, C1
Stellin, E1
Menegatti, E1
Boulton, P1
Purdy, RA2
Bosch, EP1
Dodick, DW2
Winder, CV1
Birnie, JH1
Sutton, BM1
Zuccarello, M1
Rush, JA1
Williamson, EM1
Evans, FJ1
Wada, Y2
Etoh, Y2
Ohira, A2
Kimata, H1
Koide, T1
Ishihama, H1
Mizushima, Y1
Dorsch, W1
Baur, X1
Scott, GM1
Stewart, WE1
Tyrrell, DA1
Cantell, K1
Cartwright, T1
Edy, VG1
Kingston, T1
Marks, R1
Tsukamoto, M1
Nakamura, M1
Kyuki, K3
Edwards, EK1
Horwitz, SN1
Frost, P1
Jacobi, H1
Breier, P1
Dell, HD1
Gomez, EC1
Trancik, RJ1
Misch, K1
Davies, M1
Greaves, M1
Coutts, A1
Krogstad, AL1
Swanbeck, G1
Wallin, BG1
Reeve, VE1
Matheson, MJ1
Bosnic, M1
Boehm-Wilcox, C1
Humphreys, F1
Spiro, J1
Larkin, SW1
Fraser, L1
Showell, HJ1
Williams, TJ1
Warren, JB1
Healy, E1
Reynolds, NJ1
Smith, MD1
Campbell, C1
Farr, PM4
Rees, JL1
Nose, T2
Tsurumi, K5
Ibbotson, SH1
Diffey, BL3
Kumar, JR1
Haberman, HF1
Ranadive, NS1
Simonen, P1
Hamilton, C1
Ferguson, S1
Ostwald, P1
O'Brien, M1
O'Brien, P1
Back, M1
Denham, J1
Kido, H1
Murakami, N1
Ito, A1
Kimura, K1
Kodera, N1
Doi, T1
Naruse, T1
Akter, U1
Niwa, M2
Kaida, T1
Matsuno, H1
Kozawa, O1
Uematsu, T1
Trott, KR1
Shirazi, A1
Heasman, F1
Dobrev, H1
Belgi, G1
Parslew, R1
McLoughlin, L1
Grundmann, JU1
Böckelmann, R1
Bonnekoh, B1
Gollnick, HP1
Uchida, M1
Jin, Y1
Natsume, H1
Kobayashi, D1
Sugibayashi, K1
Morimoto, Y1
Tolot, F2
Prost, G2
Guignot, B2
Pelletier, M2
Greaves, MW2
Hensby, CN2
Black, AK2
Plummer, NA2
Fincham, N1
Warin, AP2
Camp, R1
Fujimura, H2
Nozaki, M3
Eaglestein, WH1
Ginsberg, LD1
Mertz, PM1
Wiseman, EH2
McIlhenny, HM1
Bettis, JW1
Morison, WL1
Paul, BS1
Parrish, JA1
Lowe, NJ1
Virgadamo, F1
Stoughton, RB1
Adams, SS1
McCullough, KF1
Nicholson, JS1
Maruyama, Y2
Terasawa, M2
Anami, K1
Kadobe, Y1
Snyder, DS1
Eaglstein, WH1
Marsico, AR1
Peterfalvi, M1
Deraedt, R1
Benzoni, J1
Chifflot, L1
Fournex, R1
Awouters, F1
Niemegeers, CJ1
Lenaerts, PM1
Janssen, PA1
Juhlin, L1
Shroot, B1
Andersen, PH1
Abrams, K1
Maibach, H1
Segawa, Y1
Ohya, O1
Abe, T1
Omata, T1
Tsuzuike, N1
Itokazu, Y1
Yoshida, K1
Tagashira, E1
Ueda, I1
Ramsay, B1
Rice, N1
Lawrence, C1
Ståhle, M1
Hägermark, O1
Väänänen, A1
Hannuksela, M1
Mibu, H1
Torrent, J1
Izquierdo, I1
Barbanoj, MJ1
Moreno, J1
Lauroba, J1
Jané, F1
Ikai, K1
Danno, K1
Horio, T1
Narumiya, S1
Tanaka, I1
Yoshizumi, H1
Tanaka, Y1
Takeda, S1
Kamei, C1
Nakaya, N1
Kitazumi, K1
Tagami, H1
Tasaka, K1
Johansson, EA1
Sonnex, TS1
Ryan, TJ1
Imayoshi, T1
Iwahisa, Y1
Lawrence, CM1
Shuster, S1
Wilkin, JK1
Fortner, G1
Reinhardt, LA1
Flowers, OV1
Kilpatrick, SJ1
Streeter, WC1
Duperrat, B1
Puissant, A1
Chérif-Cheikh, JL1
Heintz, C1
Lainé, JY1
Julou, L1
Guyonnet, JC1
Ducrot, R1
Bardone, MC1
Detaille, JY1
Laffargue, B1
Lombardino, JG1
Navarro, J1
Stoliaroff, M1
Savy, JM1
Berny, C1
Brunaud, M1
Hayashi, M2
Yamaguchi, A1
Hiramatsu, Y2
Gupta, N1
Levy, L1
Shibuya, T1
Olson, DR1
Wheeler, WJ1
Wells, JN1
Tanaka, K1
Iizuka, Y1
Swingle, KF1
Hamilton, RR1
Harrington, JK1
Kvam, DC1
Alpermann, HG1
Hasert, K1
Barron, DI1
Copley, AR1
Vallance, DK1
Jahn, U1
Adrian, RW1
Yamamoto, H1
Saito, C1
Okamoto, T1
Awata, H1
Inukai, T1
Hirohashi, A1
Yukawa, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Combination Non Steroidal Antiinflammatory Drugs and Narrowband UVB Treatment in Non-Photoadapters[NCT05256147]3 participants (Actual)Interventional2015-08-31Terminated (stopped due to difficulty in recruiting study population)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for indomethacin and Erythema

ArticleYear
Red ear syndrome.
    Current pain and headache reports, 2007, Volume: 11, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ear; Erythema; Female; Humans; Indomethacin; Middle Aged; P

2007
The ultraviolet erythemas in man.
    The British journal of dermatology, 1978, Volume: 98, Issue:4

    Topics: Arachidonic Acids; Erythema; Humans; Indomethacin; Prostaglandins; Skin; Time Factors; Ultraviolet R

1978
[Multiple manifestations of intolerance in association with anti-inflammatory agents. Role of phenylbutazone].
    Semaine des hopitaux. Therapeutique, 1976, Volume: 52, Issue:3

    Topics: Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Tolera

1976

Trials

16 trials available for indomethacin and Erythema

ArticleYear
Prostaglandin E2 and nitric oxide mediate the acute inflammatory (erythemal) response to topical 5-aminolaevulinic acid photodynamic therapy in human skin.
    The British journal of dermatology, 2013, Volume: 169, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aminolevulinic Acid; Cyclooxygenase Inhibitors; Dinoprostone

2013
Evaluation of in-vivo topical anti-inflammatory activity of indometacin from liposomal vesicles.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:10

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Topical; Adult; Anti-Inflammatory Agents, Non-St

2004
Evaluation of indomethacin percutaneous absorption from nanostructured lipid carriers (NLC): in vitro and in vivo studies.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:5

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chromatog

2005
Effect of topical diflumidone on ultraviolet-light-induced erythema.
    Dermatologica, 1981, Volume: 162, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Benzophenones; Erythema; Human

1981
Axon-reflex-mediated vasodilatation in the psoriatic plaque?
    The Journal of investigative dermatology, 1995, Volume: 104, Issue:5

    Topics: Adult; Anesthetics; Axons; Erythema; Female; Humans; Indomethacin; Male; Middle Aged; Prostaglandin

1995
The effects of topical indomethacin and clobetasol propionate on post-cryotherapy inflammation.
    The British journal of dermatology, 1995, Volume: 132, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Child; Clobetasol; Cryotherapy; Dermatitis; Double-Blind

1995
Prolonged microvascular vasodilation induced by leukotriene B4 in human skin is cyclooxygenase independent.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adult; Arachidonic Acid; Dose-Response Relationship,

1995
The effect of topical indomethacin on ultraviolet-radiation-induced erythema.
    The British journal of dermatology, 1996, Volume: 135, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors;

1996
Do inflammatory processes contribute to radiation induced erythema observed in the skin of humans?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1998, Volume: 46, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dose Fra

1998
UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:4

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Cells, Cultured

2001
Ultraviolet irradiation-induced inflammation: effects of steroid and nonsteroid anti-inflammatory agents.
    Archives of dermatology, 1979, Volume: 115, Issue:12

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Drug Evaluation; Drug Therapy, Combination; Erythema; Fema

1979
Inflammation in human skin induced by ultraviolet irradiation.
    Postgraduate medical journal, 1977, Volume: 53, Issue:625

    Topics: Adult; Erythema; Humans; Indomethacin; Inflammation; Periodicity; Prostaglandins F; Skin; Ultraviole

1977
Separate effects of topical indomethacin on the itch response and on the flare reaction induced by histamine in human skin.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Erythema; Furans; Histamine Antagonists; Histamine Relea

1985
UV-induced erythema model: a tool in dermatopharmacology for testing the topical activity of non-steroidal anti-inflammatory agents in man.
    Methods and findings in experimental and clinical pharmacology, 1988, Volume: 10, Issue:5

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Double-Blind M

1988
Proquazone: a treatment for lymphocytic infiltration of the skin. Comparative study with 2 other nonsteroid anti-inflammatory drugs.
    Dermatologica, 1987, Volume: 174, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Erythema; Female; Humans; Ibuprofen; Indomethacin; Lymphocyte

1987
Prostaglandins and nicotinate-provoked increase in cutaneous blood flow.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:3

    Topics: Administration, Oral; Administration, Topical; Adult; Aspirin; Double-Blind Method; Doxepin; Drug In

1985

Other Studies

70 other studies available for indomethacin and Erythema

ArticleYear
Potential antiarthritic agents. 2. Benzoylacetonitriles and beta-aminocinnamonitriles.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:11

    Topics: Acetonitriles; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Edema; Erythema; Guinea P

1979
Antiinflammatory activity of isomeric phenylnaphthaleneacetic acids.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Erythema; Guinea Pigs; Isomerism; Naphthaleneacetic Acids; Struct

1977
Nonsteroidal antiinflammatory agents. 1. 10,11-Dihydro-11-oxodibenz[b, f]oxepinacetic acids and related compounds.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, E

1982
Indomethacin for burning scrotum syndrome: September 2021.
    Journal of the American Academy of Dermatology, 2021, Volume: 85, Issue:3

    Topics: Erythema; Genital Diseases, Male; Humans; Indomethacin; Male; Scrotum; Syndrome

2021
Indomethacin-Responsive Idiopathic Red Ear Syndrome: Case Report and Pathophysiology.
    Headache, 2018, Volume: 58, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ear; Erythema; Headache D

2018
Alpha-monoisostearyl glyceryl ether enhances percutaneous penetration of indometacin in-vivo.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:12

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental

2002
Cubosome dispersions as delivery systems for percutaneous administration of indomethacin.
    Pharmaceutical research, 2005, Volume: 22, Issue:12

    Topics: Adult; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cr

2005
Primary and secondary red ear syndrome: implications for treatment.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:2

    Topics: Aged; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Ear

2007
Experimental observations on flufenamic, mefenamic, and meclofenamic acids. I. Pharmacology.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Chemistry, Physical; E

1966
Some anti-inflammatory properties of 8-trifluoromethylphenothiazine-1-carboxylic acid (SK & F 22908).
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 17, Issue:1

    Topics: Animals; Erythema; Flufenamic Acid; Granuloma; Guinea Pigs; Indomethacin; Male; Phenothiazines; Phen

1967
Inhibition of erythema induced by pro-inflammatory esters of 12-deoxyphorbol.
    Acta pharmacologica et toxicologica, 1981, Volume: 48, Issue:1

    Topics: Animals; Erythema; Female; Histamine H1 Antagonists; Hydrocortisone; Indomethacin; Irritants; Mice;

1981
Percutaneous absorption and anti-inflammatory activity of indomethacin in ointment.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:7

    Topics: Animals; Dose-Response Relationship, Drug; Edema; Erythema; Indomethacin; Male; Ointments; Rats; Rat

1982
Effect of topical indomethacin on allergen-induced dual skin reactions.
    Allergy, 1980, Volume: 35, Issue:6

    Topics: Adult; Allergens; Arthus Reaction; Erythema; Histamine Release; Humans; Indomethacin; Intradermal Te

1980
Skin reactions to interferon inoculations are reduced but not abolished by purification.
    Journal of interferon research, 1980,Fall, Volume: 1, Issue:1

    Topics: Chromatography, Gel; Erythema; Histamine; Histamine Antagonists; Humans; Hypersensitivity, Delayed;

1980
Irritant reactions to dithranol in normal subjects and psoriatic patients.
    The British journal of dermatology, 1983, Volume: 108, Issue:3

    Topics: Anthracenes; Anthralin; Dose-Response Relationship, Drug; Erythema; Humans; Indomethacin; Irritants;

1983
[Anti-inflammatory effects of acemetacin (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capillary Permeability; Edema; Erythema;

1982
[Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:6

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response R

1982
Reduction of the erythema response to ultraviolet light by nonsteroidal antiinflammatory agents.
    Archives of dermatological research, 1982, Volume: 272, Issue:3-4

    Topics: Anti-Inflammatory Agents; Aspirin; Erythema; Humans; Ibuprofen; Indomethacin; Ultraviolet Rays

1982
[Anti-inflammatory action of acemetacin (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:8A

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Edema; Erythema; Female; Granuloma; Hyal

1980
Pharmacological studies of anthralin erythema.
    The British journal of dermatology, 1981, Volume: 105 Suppl 20

    Topics: Anthracenes; Anthralin; Aspirin; Betamethasone Valerate; Chlorpheniramine; Erythema; Female; Humans;

1981
The protective effect of indomethacin on photocarcinogenesis in hairless mice.
    Cancer letters, 1995, Aug-16, Volume: 95, Issue:1-2

    Topics: Animals; Carcinoma, Squamous Cell; Diet; Erythema; Female; Indomethacin; Mice; Mice, Hairless; Neopl

1995
Dissociation of erythema and p53 protein expression in human skin following UVB irradiation, and induction of p53 protein and mRNA following application of skin irritants.
    The Journal of investigative dermatology, 1994, Volume: 103, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anthralin; Dermatitis, Irritant; Erythema; Female; Gene Expression R

1994
Pharmacological studies on cutaneous inflammation induced by ultraviolet irradiation (1): quantification of erythema by reflectance colorimetry and correlation with cutaneous blood flow.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:3

    Topics: Animals; Colorimetry; Erythema; Guinea Pigs; Indomethacin; Inflammation; Laser-Doppler Flowmetry; Ma

1993
Modulation of 8-methoxypsoralen-photoinduced cutaneous inflammatory reactions by various chemotherapeutic agents in vivo.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:4

    Topics: Acetophenones; Animals; Capillary Permeability; Erythema; Ibuprofen; Indoles; Indomethacin; Masoproc

1996
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1998
Effects of several agents on UVB- and UVA plus systemic fluoroquinolone-induced erythema of guinea pig skin evaluated by reflectance colorimetry.
    Free radical biology & medicine, 1998, Volume: 24, Issue:7-8

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; beta Carotene; Butylated Hydroxytoluene; Colorimetry;

1998
Modulation of accelerated repopulation in mouse skin during daily irradiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1999, Volume: 50, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Dermatitis; Epidermal Cells; Epider

1999
Evaluation of the inhibitory activity of topical indomethacin, betamethasone valerate and emollients on UVL-induced inflammation by means of non-invasive measurements of the skin elasticity.
    Photodermatology, photoimmunology & photomedicine, 2001, Volume: 17, Issue:4

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; B

2001
Ultraviolet-B-induced erythema is mediated by nitric oxide and prostaglandin E2 in combination.
    The Journal of investigative dermatology, 2001, Volume: 117, Issue:4

    Topics: Blister; Dinoprostone; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzy

2001
Introduction of poly-L-lactic acid microspheres into the skin using supersonic flow: effects of helium gas pressure, particle size and microparticle dose on the amount introduced into hairless rat skin.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biodegradation, Environmental; Drug Carriers; Eryt

2002
[Multiple manifestations of intolerance of a combination of anti-inflammatory drugs. Role of phenylbutazone].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1975, Dec-09, Volume: 51, Issue:48

    Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Duodenal Ulcer; Erythema;

1975
Inflammatory reactions induced by ultraviolet irradiation.
    Bulletin du cancer, 1978, Volume: 65, Issue:3

    Topics: Arachidonic Acids; Cell Differentiation; Cyclic AMP; Erythema; Humans; Indomethacin; Inflammation; M

1978
[Anti-inflammatory property of 6-chloro-5-cyclohexyl-1-indancarboxylic acid (TAI-284) (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Capillary Permeability; Death, Sud

1977
Flumizole, a new nonsteroidal anti-inflammatory agent.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:9

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Biological Availability; Cyclooxygenase Inh

1975
The effects of indomethacin on long-wave ultraviolet-induced delayed erythema.
    The Journal of investigative dermatology, 1977, Volume: 68, Issue:3

    Topics: Administration, Oral; Administration, Topical; Adult; Erythema; Ficusin; Humans; Indomethacin; Injec

1977
Anti-inflammatory properties of a prostaglandin antagonist, a corticosteroid and indomethacin in experimental contact dermatitis.
    The British journal of dermatology, 1977, Volume: 96, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Erythema; Indometha

1977
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:11

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cap

1975
[Pharmacological studies of 2-(5H-(1)benzopyrano(2,3-b)pyridin-7-yl)propionic acid (Y-8004). (I) Anti-inflammatory, analgesic and antipyretic actions].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:8

    Topics: Adrenal Cortex; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability

1975
Cutaneous effects of topical indomethacin, an inhibitor of prostaglandin synthesis, on UV-damaged skin.
    The Journal of investigative dermatology, 1975, Volume: 64, Issue:5

    Topics: Administration, Topical; Animals; Cell Survival; Depression, Chemical; DNA; Erythema; Female; Guinea

1975
Dichotomy in response to indomethacin in UV-C and UV-B induced ultraviolet light inflammation.
    The Journal of investigative dermatology, 1975, Volume: 65, Issue:2

    Topics: Adult; Erythema; Female; Humans; Indomethacin; Inflammation; Injections, Intradermal; Male; Prostagl

1975
Floctafenine, a new non-narcotic analgesic.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 216, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dextropropoxyphene; D

1975
Suprofen, a potent antagonist of ultraviolet-erythema in guinea-pigs.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; E

1975
Effect of drugs on the early and late phase UV erythema.
    Acta dermato-venereologica, 1992, Volume: 72, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Erythema; Female; Humans; Indomethacin; Male; Middle Aged; Photosen

1992
Ultraviolet B dose-dependent inflammation in humans: a reflectance spectroscopic and laser Doppler flowmetric study using topical pharmacologic antagonists on irradiated skin.
    Photodermatology, photoimmunology & photomedicine, 1992, Volume: 9, Issue:1

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Diphenhyd

1992
Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; E

1992
The effect of indomethacin on anthralin inflammation.
    The British journal of dermatology, 1992, Volume: 126, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anthralin; Dermatitis, Contact; Edema; Erythema; F

1992
UVB erythema inhibited by topically applied substances.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aspirin; Betamethasone; Butylated Hydroxytoluene; Diphenhydram

1989
Effect of indomethacin on UVB- and UVA-induced erythema in polymorphic light eruption.
    Journal of the American Academy of Dermatology, 1989, Volume: 21, Issue:2 Pt 1

    Topics: Administration, Topical; Adult; Aged; Erythema; Female; Humans; Indomethacin; Middle Aged; Photosens

1989
Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid. 2nd communication: inhibitory effects on acute inflammation and prostaglandin-related reactions.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Benzopyrans; Benzothiepins;

1986
Ear swelling in response to UVB irradiation.
    Archives of dermatological research, 1986, Volume: 278, Issue:6

    Topics: Animals; Betamethasone; Cimetidine; Diphenhydramine; Ear, External; Edema; Erythema; Indomethacin; M

1986
Pharmacological profiles of 2-carboxyphenyl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate and 2-[(2-carboxyphenoxy)-carbonyl]phenyl-1-(4-chlorobenzoyl)-5-meth oxy-2- methylindole-3-acetate, new antiinflammatory agents.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1986
An investigation of the angry back syndrome using Trafuril.
    The British journal of dermatology, 1987, Volume: 116, Issue:3

    Topics: Aspirin; Erythema; False Positive Reactions; Furans; Humans; Indomethacin; Nicotinic Acids; Patch Te

1987
A quantitative study of the effect of topical indomethacin on cutaneous erythema induced by UVB and UVC radiation.
    The British journal of dermatology, 1986, Volume: 115, Issue:4

    Topics: Administration, Topical; Dose-Response Relationship, Radiation; Erythema; Humans; Indomethacin; Mode

1986
[Anti-inflammatory effect of topically applied pranoprofen-gel].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Benzopyrans; Capillary Permeability; Ede

1985
Mechanism of anthralin inflammation. I. Dissociation of response to clobetasol and indomethacin.
    The British journal of dermatology, 1985, Volume: 113, Issue:1

    Topics: Adult; Aged; Anthracenes; Anthralin; Betamethasone; Clobetasol; Dermatitis, Contact; Edema; Erythema

1985
[Bullous toxidermia (Duhring-Brocq disease type) induced by indomethacin].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1969, Volume: 76, Issue:1

    Topics: Aged; Blister; Drug Eruptions; Erythema; Female; Humans; Indomethacin; Parapsoriasis

1969
[General pharmacological properties of methiazinic acid (16091 RP)].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Abscess; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Autonomic Nervous Syste

1969
Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:11

    Topics: Administration, Oral; Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Carrageenan;

1974
[Pharmacologic properties of a new, nonsteroidal anti-inflammatory agent, bucloxic acid (804 CB)].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:9A SUPPL

    Topics: Administration, Oral; Adrenal Glands; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Cycl

1974
[Pharmacological studies on niflumic acid, with special reference to the comparison with fenametes. 1. Anti-inflammatory and analgesic actions].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:6

    Topics: Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability;

1972
Delayed manifestation of ultraviolet reaction in the guinea-pig caused by anti-inflammatory drugs.
    British journal of pharmacology, 1973, Volume: 47, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Body Weight; Erythema; Guinea Pigs; Indomethacin; Permea

1973
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 1. On acute inflammation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Electrolytes; Eryth

1973
Rigid analogs of indomethacin.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:2

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Erythema; Guinea Pigs; Indomethacin; Phenanthridines; R

1974
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid;

1972
3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Car

1971
[Delay of UV-erythema by thiophencarbonic acid derivatives].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:2

    Topics: Acids; Animals; Anti-Inflammatory Agents; Depression, Chemical; Erythema; Flufenamic Acid; Guinea Pi

1970
[Clinical picture and therapy of dermatomyositis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Mar-15, Volume: 25, Issue:6

    Topics: Adolescent; Calcinosis; Child; Dermatomyositis; Erythema; Female; Humans; Indomethacin; Prednisone

1970
Anti-inflammatory and related properties of 4-(p-biphenylyl)-3-hydroxybutyric acid.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Pressure; Bronchial

1968
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo

1969
Synthesis and pharmacology of a new potential anti-inflammatory drug, 1-(3',4'-methylenedioxybenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid (ID-955).
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:6

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Blood Proteins; Capillary Permeability; Car

1969