Page last updated: 2024-10-29

indomethacin and Erosive Duodenitis

indomethacin has been researched along with Erosive Duodenitis in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
" This study was designed to investigate the effects of a recently developed biotechnological product, a nano-formulation of olmesartan medoxomil (OM) - olmesartan medoxomil zeinmersomes (OMZ) - for the treatment of indomethacin-induced duodenitis in rats."8.31A novel nano-formulation of olmesartan medoxomil with improved delivery and efficacy in the treatment of indomethacin-induced duodenitis in rats. ( Alqurashi, TM; Murad, HA, 2023)
"The effect of ketoprofen, a nonsteroidal anti-inflammatory drug, was tested on the upper gastrointestinal tract (UGIT) in patients with osteoarthritis."5.06A prospective endoscopic study of the effect of Orudis and Oruvail on the upper gastrointestinal tract, in patients with osteoarthritis. ( Collins, AJ; Davies, J; Dixon, AS, 1988)
" This study was designed to investigate the effects of a recently developed biotechnological product, a nano-formulation of olmesartan medoxomil (OM) - olmesartan medoxomil zeinmersomes (OMZ) - for the treatment of indomethacin-induced duodenitis in rats."4.31A novel nano-formulation of olmesartan medoxomil with improved delivery and efficacy in the treatment of indomethacin-induced duodenitis in rats. ( Alqurashi, TM; Murad, HA, 2023)
" The bioavailability of indomethacin in the three groups does not differ significantly."2.66Protective effect of rioprostil on indomethacin-induced lesions of gastric and duodenal mucosa in healthy volunteers. ( Gerova, Z; Kirkov, V; Popov, P; Vlahov, V, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Murad, HA1
Alqurashi, TM1
Ivey, KJ1
Swift, GL1
Arnold, J1
Williams, GT1
Williams, BD1
Rhodes, J1
Khan, F1
Vlahov, V1
Kirkov, V1
Popov, P1
Gerova, Z1
Collins, AJ1
Davies, J1
Dixon, AS1

Trials

3 trials available for indomethacin and Erosive Duodenitis

ArticleYear
A comparison of upper gastrointestinal mucosal damage by standard and delayed-release indomethacin.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Double-Blind Method; Duodenal Ulcer; Du

1992
Protective effect of rioprostil on indomethacin-induced lesions of gastric and duodenal mucosa in healthy volunteers.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 164

    Topics: Adult; Anti-Ulcer Agents; Double-Blind Method; Duodenitis; Gastritis; Humans; Indomethacin; Male; Pr

1989
A prospective endoscopic study of the effect of Orudis and Oruvail on the upper gastrointestinal tract, in patients with osteoarthritis.
    British journal of rheumatology, 1988, Volume: 27, Issue:2

    Topics: Administration, Oral; Delayed-Action Preparations; Double-Blind Method; Duodenitis; Endoscopy; Esoph

1988

Other Studies

2 other studies available for indomethacin and Erosive Duodenitis

ArticleYear
A novel nano-formulation of olmesartan medoxomil with improved delivery and efficacy in the treatment of indomethacin-induced duodenitis in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2023, Volume: 56

    Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Caspase 3; Duodenitis; Indomethacin;

2023
Drugs, gastritis, and peptic ulcer.
    Journal of clinical gastroenterology, 1981, Volume: 3, Issue:Suppl 2

    Topics: Acetaminophen; Animals; Aspirin; Bicarbonates; Cimetidine; Duodenitis; Gastric Acid; Gastric Mucosa;

1981