indomethacin has been researched along with Enuresis in 4 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Enuresis: Involuntary discharge of URINE after expected age of completed development of urinary control. This can happen during the daytime (DIURNAL ENURESIS) while one is awake or during sleep (NOCTURNAL ENURESIS). Enuresis can be in children or in adults (as persistent primary enuresis and secondary adult-onset enuresis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prostaglandin synthesis inhibitor indomethacin (used as a suppository) was compared to placebo in the treatment of primary nocturnal enuresis in a double-blind crossover study." | 9.06 | Indomethacin suppository to treat primary nocturnal enuresis: double-blind study. ( al-Waili, NS, 1989) |
| " Enuretics were then given 50 mg indomethacin suppositories each night; urine volume, urinary osmolality and electrolytes, serum osmolality and electrolytes and urinary nitrite were assayed before indomethacin treatment and after 15 days of treatment." | 7.71 | Increased urinary nitrite excretion in primary enuresis: effects of indomethacin treatment on urinary and serum osmolality and electrolytes, urinary volumes and nitrite excretion. ( Al-Waili, NS, 2002) |
| " The dosage of desmopressin (group A, n = 31 ) was 20 microg/day and the dosage of indomethacin (group B, n = 29) was 100 mg/day." | 6.69 | Desmopressin versus indomethacin treatment in primary nocturnal enuresis and the role of prostaglandins. ( Hasanoğlu, E; Sener, F; Söylemezoğlu, O, 1998) |
| "This encouraged to use carbamazepine to treat primary enuresis." | 6.69 | Carbamazepine to treat primary nocturnal enuresis: double-blind study. ( Al-Waili, NS, 2000) |
| " Enuretics were then given 50 mg indomethacin suppositories each night; urine volume, urinary osmolality and electrolytes, serum osmolality and electrolytes and urinary nitrite were assayed before indomethacin treatment and after 15 days of treatment." | 3.71 | Increased urinary nitrite excretion in primary enuresis: effects of indomethacin treatment on urinary and serum osmolality and electrolytes, urinary volumes and nitrite excretion. ( Al-Waili, NS, 2002) |
| " The dosage of desmopressin (group A, n = 31 ) was 20 microg/day and the dosage of indomethacin (group B, n = 29) was 100 mg/day." | 2.69 | Desmopressin versus indomethacin treatment in primary nocturnal enuresis and the role of prostaglandins. ( Hasanoğlu, E; Sener, F; Söylemezoğlu, O, 1998) |
| "This encouraged to use carbamazepine to treat primary enuresis." | 2.69 | Carbamazepine to treat primary nocturnal enuresis: double-blind study. ( Al-Waili, NS, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Waili, NS | 3 |
| Sener, F | 1 |
| Hasanoğlu, E | 1 |
| Söylemezoğlu, O | 1 |
3 trials available for indomethacin and Enuresis
| Article | Year |
|---|---|
Desmopressin versus indomethacin treatment in primary nocturnal enuresis and the role of prostaglandins.
Topics: Adolescent; Child; Deamino Arginine Vasopressin; Dinoprostone; Enuresis; Follow-Up Studies; Humans; | 1998 |
Carbamazepine to treat primary nocturnal enuresis: double-blind study.
Topics: Adolescent; Carbamazepine; Child; Cross-Over Studies; Double-Blind Method; Enuresis; Female; Humans; | 2000 |
Indomethacin suppository to treat primary nocturnal enuresis: double-blind study.
Topics: Adolescent; Child; Double-Blind Method; Enuresis; Female; Humans; Indomethacin; Male; Randomized Con | 1989 |
1 other study available for indomethacin and Enuresis
| Article | Year |
|---|---|
Increased urinary nitrite excretion in primary enuresis: effects of indomethacin treatment on urinary and serum osmolality and electrolytes, urinary volumes and nitrite excretion.
Topics: Adolescent; Case-Control Studies; Child; Chlorides; Cyclooxygenase Inhibitors; Electrolytes; Enuresi | 2002 |