Page last updated: 2024-10-29

indomethacin and Enteritis

indomethacin has been researched along with Enteritis in 43 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Enteritis: Inflammation of any segment of the SMALL INTESTINE.

Research Excerpts

ExcerptRelevanceReference
"Ingestion of DON mycotoxin at concentrations representative of human real-world exposure worsened the development of indomethacin-induced enteritis and colitis-associated CRC in mice."8.31Low dose dietary contamination with deoxynivalenol mycotoxin exacerbates enteritis and colorectal cancer in mice. ( Beury, D; Body-Malapel, M; Caboche, S; Desai, MS; Djouina, M; Dubuquoy, L; Hot, D; Launay, D; Lecointe, K; Steimle, A; Vignal, C; Waxin, C, 2023)
" We evaluated the role of the pro-inflammatory cytokine TNF-alpha on nitric oxide synthase (NOS) expression in indomethacin-induced jejunoileitis in rats."7.76TNF-alpha modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis. ( Levine, RA; Nandi, J; Saud, B; Yang, ZJ; Zinkievich, JM, 2010)
" Therefore, we evaluated the biological effects of lansoprazole, a PPI used in the clinical area, in the setting of experimental rat non-steroidal anti-inflammatory drug-induced enteritis."7.73Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis. ( Ichikawa, H; Kuroda, M; Naito, Y; Okanoue, T; Okuda, T; Takagi, T; Yoshida, N; Yoshikawa, T, 2006)
" Rats with indomethacin-induced enteritis were orally administered Rb, Mn, and Zn as tracers."7.72Use of rubidium, manganese, and zinc as tracers to measure intestinal permeability by PIXE analysis: basal study in an experimental enteritis model. ( Imaseki, H; Joshima, H; Nakao, K; Saito, Y; Suzuki, Y; Tamanoi, I, 2004)
"Ingestion of DON mycotoxin at concentrations representative of human real-world exposure worsened the development of indomethacin-induced enteritis and colitis-associated CRC in mice."4.31Low dose dietary contamination with deoxynivalenol mycotoxin exacerbates enteritis and colorectal cancer in mice. ( Beury, D; Body-Malapel, M; Caboche, S; Desai, MS; Djouina, M; Dubuquoy, L; Hot, D; Launay, D; Lecointe, K; Steimle, A; Vignal, C; Waxin, C, 2023)
"β-casofensin exerts protective effects in indomethacin-induced enteritis through preservation of goblet cells and improvement in wound healing."3.83Protective effects of β-casofensin, a bioactive peptide from bovine β-casein, against indomethacin-induced intestinal lesions in rats. ( Benoit, B; Bessette, C; Bruno, J; Estienne, M; Ferrier, L; Léonil, J; Plaisancié, P; Sekkal, S; Théodorou, V, 2016)
" Administration of indomethacin, a non-steroidal anti-inflammatory drug (NSAID) that causes enteritis, led to rapid and restricted proximal small intestinal injuries in Gata4 mutant mice as opposed to control mice."3.83Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury. ( Allaire, JM; Asselin, C; Bélanger, É; Boudreau, F; Bruneau, J; Gendron, FP; Jones, C; Lepage, D; Menendez, A; Perreault, N; Tremblay, S, 2016)
" This study aimed to investigate the effects of hemin, an HO-1 inducer, on indomethacin-induced enteritis in mice."3.79Hemin ameliorates indomethacin-induced small intestinal injury in mice through the induction of heme oxygenase-1. ( Fukui, A; Handa, O; Harusato, A; Higashimura, Y; Hirai, Y; Ichikawa, H; Kamada, K; Katada, K; Kugai, M; Mizusima, K; Naito, Y; Takagi, T; Tsuji, T; Uchiyama, K; Yagi, N; Yamada, S; Yoriki, H; Yosikawa, T, 2013)
" We evaluated the role of the pro-inflammatory cytokine TNF-alpha on nitric oxide synthase (NOS) expression in indomethacin-induced jejunoileitis in rats."3.76TNF-alpha modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis. ( Levine, RA; Nandi, J; Saud, B; Yang, ZJ; Zinkievich, JM, 2010)
" Therefore, we evaluated the biological effects of lansoprazole, a PPI used in the clinical area, in the setting of experimental rat non-steroidal anti-inflammatory drug-induced enteritis."3.73Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis. ( Ichikawa, H; Kuroda, M; Naito, Y; Okanoue, T; Okuda, T; Takagi, T; Yoshida, N; Yoshikawa, T, 2006)
" Rats with indomethacin-induced enteritis were orally administered Rb, Mn, and Zn as tracers."3.72Use of rubidium, manganese, and zinc as tracers to measure intestinal permeability by PIXE analysis: basal study in an experimental enteritis model. ( Imaseki, H; Joshima, H; Nakao, K; Saito, Y; Suzuki, Y; Tamanoi, I, 2004)
"We investigated the effect of dexamethasone on indomethacin-induced ulceration in the rat."3.69Dexamethasone promotes ulcer plugging in experimental enteritis. ( Anthony, A; Dhillon, AP; Pounder, RE; Sim, R; Wakefield, AJ, 1994)
"An ulcerative enterocolitis was induced in dogs by two drugs; cinchophen given intravenously or indomethacin given orally."3.66Ulcerative enterocolitis in dogs induced by drugs. ( Hetenyi, C; Orizaga, M; Rowsell, H; Stewart, TH, 1980)
" However, its low oral bioavailability is a major obstacle to its potential use."1.48Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide. ( Chen, YC; Wang, CC; Wu, MT; Wu, YT; Yen, CC, 2018)
"Cotreatment with omeprazole did not reduce indomethacin-induced intestinal bleeding."1.42Suppression of contractile activity in the small intestine by indomethacin and omeprazole. ( Bhattarai, D; Dial, EJ; Lichtenberger, LM; Phan, TM; Uray, K, 2015)
"Oral IND@RNP(O) administration is a useful approach for improving the oral bioavailability of IND and suppressing its adverse effects."1.40Indomethacin-loaded redox nanoparticles improve oral bioavailability of indomethacin and suppress its small intestinal inflammation. ( Chonpathompikunlert, P; Matsui, H; Nagasaki, Y; Sha, S; Vong, LB; Yoshitomi, T, 2014)
"The ovalbumin serum level was higher in indomethacin-treated mice and the increase was proportional to the dose of indomethacin."1.29Decrease in systemic tolerance to fed ovalbumin in indomethacin-treated mice. ( Belaiche, J; Deprez, M; Franchimont, D; Lamproye, A; Louis, E; Mahieu, P; Schaaf, N, 1996)
"Indomethacin treatment significantly decreased bile acid-independent bile flow and biliary secretion of bile acid and cholesterol, while increasing biliary phospholipid output in vivo."1.29Bile secretion in rats with indomethacin-induced intestinal inflammation. ( Hayakawa, T; Hoshino, M; Inagaki, T; Kamiya, Y; Miyaji, M; Mizuno, K; Nakazawa, T; Ohhara, H; Takeuchi, T; Uchida, A; Yamada, H; Yamada, T, 1996)
"Indomethacin treated animals demonstrated significantly less polymorphonuclear leukocyte infiltration and decreased degeneration."1.28The effect of indomethacin on acute radiation induced gastrointestinal injury: a morphologic study. ( Halter, SA; Rose, PG; Su, CM, 1992)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19904 (9.30)18.7374
1990's13 (30.23)18.2507
2000's12 (27.91)29.6817
2010's13 (30.23)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Djouina, M1
Waxin, C1
Caboche, S1
Lecointe, K1
Steimle, A1
Beury, D1
Desai, MS1
Hot, D1
Dubuquoy, L1
Launay, D1
Vignal, C1
Body-Malapel, M1
Yen, CC1
Chen, YC1
Wu, MT1
Wang, CC1
Wu, YT1
Yoshitomi, T1
Sha, S1
Vong, LB1
Chonpathompikunlert, P1
Matsui, H1
Nagasaki, Y1
Ciobanu, L2
Taulescu, M1
Prundus, R1
Diaconu, B1
Andreica, V1
Catoi, C2
Pascu, O1
Tantau, M1
Yamamoto, A1
Itoh, T1
Nasu, R1
Nishida, R1
Lichtenberger, LM1
Bhattarai, D1
Phan, TM1
Dial, EJ1
Uray, K1
Bessette, C1
Benoit, B1
Sekkal, S1
Bruno, J1
Estienne, M1
Léonil, J1
Ferrier, L1
Théodorou, V1
Plaisancié, P1
Kwak, DS1
Lee, OY1
Lee, KN1
Jun, DW1
Lee, HL1
Yoon, BC1
Choi, HS1
Lepage, D1
Bélanger, É1
Jones, C1
Tremblay, S1
Allaire, JM1
Bruneau, J1
Asselin, C1
Perreault, N1
Menendez, A1
Gendron, FP1
Boudreau, F1
Okayama, T1
Yoshida, N3
Uchiyama, K2
Takagi, T4
Ichikawa, H4
Yoshikawa, T3
Nandi, J2
Saud, B2
Zinkievich, JM2
Yang, ZJ1
Levine, RA2
Kakimoto, K1
Takai, S1
Murano, M1
Ishida, K1
Yoda, Y1
Inoue, T1
Jin, D1
Umegaki, E1
Higuchi, K1
Jorge, E1
Vergara, P2
Martin, MT2
Yoriki, H1
Naito, Y3
Mizusima, K1
Hirai, Y1
Harusato, A1
Yamada, S1
Tsuji, T1
Kugai, M1
Fukui, A1
Higashimura, Y1
Katada, K1
Kamada, K1
Handa, O2
Yagi, N1
Yosikawa, T1
Nadăş, GC1
Taulescu, MA1
Fiţ, NI1
Flore, C1
Răpuntean, S1
Bouari, CM1
Porras, M1
Soler, M1
Nakao, K1
Suzuki, Y1
Imaseki, H1
Joshima, H1
Tamanoi, I1
Saito, Y1
Kuroda, M1
Okuda, T2
Okanoue, T1
Vymiatina, ZK1
Ivanova, LA1
Krylova, SG1
Palma, DT1
Kokura, S1
Stewart, TH1
Hetenyi, C1
Rowsell, H1
Orizaga, M1
Anthony, A2
Dhillon, AP1
Sim, R1
Pounder, RE1
Wakefield, AJ1
Yamada, T4
Deitch, E1
Specian, RD1
Perry, MA1
Sartor, RB1
Grisham, MB2
Woodard, JP1
Chen, W1
Keku, EO1
Liu, SC1
Lecce, JG1
Rhoads, JM1
Louis, E1
Franchimont, D1
Deprez, M1
Lamproye, A1
Schaaf, N1
Mahieu, P1
Belaiche, J1
Kremer, JM1
Malamood, H1
Maliakkal, B1
Rodgers, JB1
Ross, JS1
Cooper, JA1
Battarbee, HD1
Johnson, GG1
Zavecz, JH1
Hoshino, M3
Hayakawa, T3
Kamiya, Y1
Ohhara, H2
Mizuno, K1
Yamada, H2
Nakazawa, T2
Inagaki, T2
Uchida, A3
Miyaji, M2
Takeuchi, T2
Kullmann, F1
Gross, V1
Rüschoff, J1
Arndt, H1
Benda, W1
Winkler von Mohrenfels, A1
Schölmerich, J1
Iida, M1
Ogasawara, T1
Hasegawa, C1
Murasaki, G1
Hirata, A1
László, F2
Whittle, BJ2
Boushey, RP1
Yusta, B1
Drucker, DJ1
Evans, SM1
Beck, PL1
Xavier, R1
Lu, N1
Nanda, NN1
Dinauer, M1
Podolsky, DK1
Seed, B1
Ruh, J1
Vogel, F1
Schmidt, E1
Stadnyk, AW1
Dollard, C1
Issekutz, TB1
Issekutz, AC1
Sigthorsson, G1
Simpson, RJ1
Walley, M1
Foster, R1
Hotz-Behoftsitz, C1
Palizban, A1
Pombo, J1
Watts, J1
Morham, SG1
Bjarnason, I1
Fang, WF1
Broughton, A1
Jacobson, ED1
Rose, PG1
Halter, SA1
Su, CM1
Brunsson, I1
Calabro, JJ1
Garg, SL1
Khoury, MI1
Long, JA1
Birbara, CA1

Trials

1 trial available for indomethacin and Enteritis

ArticleYear
Fish oil dietary supplementation for prevention of indomethacin induced gastric and small bowel toxicity in healthy volunteers.
    The Journal of rheumatology, 1996, Volume: 23, Issue:10

    Topics: Adult; Biopsy; Double-Blind Method; Endoscopy; Enteritis; Female; Fish Oils; Food, Fortified; Gastri

1996

Other Studies

42 other studies available for indomethacin and Enteritis

ArticleYear
Low dose dietary contamination with deoxynivalenol mycotoxin exacerbates enteritis and colorectal cancer in mice.
    The Science of the total environment, 2023, Nov-20, Volume: 900

    Topics: Animals; Colitis; Colorectal Neoplasms; Diet; Enteritis; Humans; Indomethacin; Mice; Mycotoxins

2023
Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Administration, Oral; alpha-Tocopherol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological

2018
Indomethacin-loaded redox nanoparticles improve oral bioavailability of indomethacin and suppress its small intestinal inflammation.
    Therapeutic delivery, 2014, Volume: 5, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chromatography, High Pres

2014
Effects of rifaximin on indomethacin-induced intestinal damage in guinea-pigs.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enteritis; Female; Gastrointestinal Agents; Guinea

2014
Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats.
    World journal of gastroenterology, 2014, Mar-14, Volume: 20, Issue:10

    Topics: Alginates; Anemia; Animals; Anti-Ulcer Agents; Atrophy; Bacterial Translocation; Biomarkers; Capilla

2014
Suppression of contractile activity in the small intestine by indomethacin and omeprazole.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, May-01, Volume: 308, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Enteritis; Gastrointestinal Hemorrhage

2015
Protective effects of β-casofensin, a bioactive peptide from bovine β-casein, against indomethacin-induced intestinal lesions in rats.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:4

    Topics: Administration, Oral; Animals; Caseins; Cattle; Enteritis; HT29 Cells; Humans; Indomethacin; Intesti

2016
The Effect of DA-6034 on Intestinal Permeability in an Indomethacin-Induced Small Intestinal Injury Model.
    Gut and liver, 2016, May-23, Volume: 10, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose

2016
Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury.
    Scientific reports, 2016, 11-09, Volume: 6

    Topics: Animals; Claudins; Enteritis; GATA4 Transcription Factor; Gene Expression Regulation; Indomethacin;

2016
Mast cells are involved in the pathogenesis of indomethacin-induced rat enteritis.
    Journal of gastroenterology, 2009, Volume: 44 Suppl 19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CXCL1; Enteritis; Indomethacin; Intestin

2009
TNF-alpha modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis.
    Molecular and cellular biochemistry, 2010, Volume: 336, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Enteritis; Hyperbaric Oxygenation; Ileitis; Ileum; Indome

2010
Significance of chymase-dependent matrix metalloproteinase-9 activation on indomethacin-induced small intestinal damages in rats.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chymases; Enteritis; Enzyme Inhibitors; Indomethac

2010
Ileal inducible nitric oxide synthase mRNA expression in response to stress is modified in Sprague-Dawley rats exposed to a previous intestinal inflammation.
    Stress (Amsterdam, Netherlands), 2012, Volume: 15, Issue:1

    Topics: Animals; Bacterial Translocation; Defecation; Enteritis; Gastrointestinal Motility; Ileum; Immersion

2012
Hemin ameliorates indomethacin-induced small intestinal injury in mice through the induction of heme oxygenase-1.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:4

    Topics: Animals; Blotting, Western; Chemokines; Cytokines; Disease Models, Animal; DNA Primers; Enteritis; E

2013
The interplay between NSAIDs and Candida albicans on the gastrointestinal tract of guinea pigs.
    Mycopathologia, 2013, Volume: 175, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Candida albicans; Enteritis; Female; Gastrointesti

2013
Intestinal motor disorders associated with cyclical bacterial overgrowth in a rat model of enteritis.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:1

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Bacterial Infections; Bac

2004
Use of rubidium, manganese, and zinc as tracers to measure intestinal permeability by PIXE analysis: basal study in an experimental enteritis model.
    Biological trace element research, 2004, Volume: 98, Issue:1

    Topics: Animals; Crohn Disease; Enteritis; Indomethacin; Inflammation; Intestinal Absorption; Intestine, Sma

2004
Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis.
    International journal of molecular medicine, 2006, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine

2006
[Experimental study of the impact of a single use of indometacine on the morphological structure of the mucous coat of the stomach and small intestine].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2006, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enteritis; Gastric Mucosa; Indomethacin; Intestina

2006
5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blotting, Western; Cyclooxygenase Inhi

2008
CV-11974, angiotensin II type I receptor antagonist, reduces the severity of indomethacin-induced rat enteritis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimida

2008
Ulcerative enterocolitis in dogs induced by drugs.
    The Journal of pathology, 1980, Volume: 131, Issue:4

    Topics: Animals; Colitis; Dogs; Enteritis; Female; Indomethacin; Intestinal Diseases; Male; Peyer's Patches;

1980
Dexamethasone promotes ulcer plugging in experimental enteritis.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:6

    Topics: Animals; Dexamethasone; Enteritis; Fibrin; Hematologic Tests; Indomethacin; Intestinal Mucosa; Jejun

1994
Mechanisms of acute and chronic intestinal inflammation induced by indomethacin.
    Inflammation, 1993, Volume: 17, Issue:6

    Topics: Acute Disease; Animals; Bacteria; Bile; Chronic Disease; Disease Models, Animal; Enteritis; Indometh

1993
Altered jejunal potassium (Rb+) transport in piglet rotavirus enteritis.
    The American journal of physiology, 1993, Volume: 265, Issue:2 Pt 1

    Topics: Acute Disease; Animals; Animals, Newborn; Biological Transport; Enteritis; Indomethacin; Jejunum; Ou

1993
Decrease in systemic tolerance to fed ovalbumin in indomethacin-treated mice.
    International archives of allergy and immunology, 1996, Volume: 109, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Enteritis; Femal

1996
Superior mesenteric artery blood flow and indomethacin-induced intestinal injury and inflammation.
    The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 1

    Topics: Animals; Blood Pressure; Enteritis; Indomethacin; Intestine, Small; Male; Peroxidase; Rats; Rats, Sp

1996
Bile secretion in rats with indomethacin-induced intestinal inflammation.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 1

    Topics: Animals; Bile; Bile Acids and Salts; Blood; Clindamycin; Enteritis; Horseradish Peroxidase; Indometh

1996
Effect of ursodeoxycholic acid on the inflammatory activity of indomethacin-induced intestinal inflammation in rats.
    Zeitschrift fur Gastroenterologie, 1997, Volume: 35, Issue:3

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dose-Response Rela

1997
Taurochenodeoxycholic acid ameliorates and ursodeoxycholic acid exacerbates small intestinal inflammation.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 1

    Topics: Animals; Bile; Blood; Body Weight; Diet; Dose-Response Relationship, Drug; Eating; Enteritis; Indome

1997
Dietary diosgenin attenuates subacute intestinal inflammation associated with indomethacin in rats.
    The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 1

    Topics: Acute Disease; Animals; Bile; Bile Acids and Salts; Blood; Body Weight; Cholesterol; Diet; Diosgenin

1997
Role of nitric oxide and platelet-activating factor in the initiation of indomethacin-provoked intestinal inflammation in rats.
    European journal of pharmacology, 1998, Mar-05, Volume: 344, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enteritis; Ileum; Indomethacin; Jejunum; Male; Nit

1998
Glucagon-like peptide 2 decreases mortality and reduces the severity of indomethacin-induced murine enteritis.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enteritis; Epithelial Cells; Female; Glucagon; Hum

1999
Site-specific lesion formation, inflammation and inducible nitric oxide synthase expression by indomethacin in the rat intestine.
    European journal of pharmacology, 2000, Feb-04, Volume: 388, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Colitis; Enteritis; Enzyme

2000
Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice.
    Gastroenterology, 2000, Volume: 119, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; DNA-Binding Proteins; Enteritis; Fucosy

2000
In vivo assessment of villous microcirculation in the rat small intestine in indomethacin-induced inflammation: role of mast-cell stabilizer Ketotifen.
    Acta physiologica Scandinavica, 2000, Volume: 170, Issue:2

    Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Blood Flow Veloc

2000
Neutrophil migration into indomethacin induced rat small intestinal injury is CD11a/CD18 and CD11b/CD18 co-dependent.
    Gut, 2002, Volume: 50, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Cell Movement; Cytokines;

2002
COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice.
    Gastroenterology, 2002, Volume: 122, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase

2002
Indomethacin-induced intestinal inflammation.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:9

    Topics: Animals; Colchicine; Dexamethasone; DNA; Enteritis; Female; Ileum; Indomethacin; Intestinal Mucosa;

1977
The effect of indomethacin on acute radiation induced gastrointestinal injury: a morphologic study.
    Journal of surgical oncology, 1992, Volume: 49, Issue:4

    Topics: Acute Disease; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enteritis; I

1992
Enteric nerves mediate the fluid secretory response due to Salmonella typhimurium R5 infection in the rat small intestine.
    Acta physiologica Scandinavica, 1987, Volume: 131, Issue:4

    Topics: Animals; Atropine; Enteritis; Hexamethonium; Hexamethonium Compounds; Ileum; Indomethacin; Intestina

1987
Reiter's syndrome.
    American family physician, 1974, Volume: 9, Issue:4

    Topics: Adult; Africa; Arthritis, Reactive; Asia; Aspirin; Child, Preschool; Diagnosis, Differential; Dysent

1974