Page last updated: 2024-10-29

indomethacin and Endometrioma

indomethacin has been researched along with Endometrioma in 8 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.

Research Excerpts

ExcerptRelevanceReference
"To study the production of prostacyclin (PGI2) and thromboxane A2 (TxA2) in endometriosis in vitro, samples of endometriotic tissue taken during operation from 6 women were superfused for 4."5.05Prostaglandins and endometriosis. ( Viinikka, L; Ylikorkala, O, 1983)
"Fertile controls (n = 27), infertile controls (n = 20), untreated endometriosis (n = 43), danazol-treated endometriosis (n = 22), and gonadotropin-releasing hormone agonist (GnRH-a)-treated endometriosis (n = 13) were tested."3.68The development of cytotoxicity in peritoneal macrophages from women with endometriosis. ( Braun, DP; Dmowski, WP; Gebel, H; Rana, N; Rotman, C, 1992)
"There were no differences in the recurrence between the groups with or without GnRH analogs."2.70Use of intraperitoneal interferon alpha-2b therapy after conservative surgery for endometriosis and postoperative medical treatment with depot gonadotropin-releasing hormone analog: a randomized clinical trial. ( Acién, P; Campos, A; Gomez-Torres, MJ; Gutierrez, M; Quereda, F; Velasco, I, 2002)
"Indomethacin treatment raised the incidence of psychic complaints over those with ASA or placebo (P."2.65Prostaglandin biosynthesis inhibitors and endometriosis. ( Kauppila, A; Puolakka, J; Ylikorkala, O, 1979)
"Endometriosis is a disease characterized by the growth of endometrial tissue outside the uterus and is associated with chronic pelvic pain."1.42Oxidation-sensitive nociception involved in endometriosis-associated pain. ( Brose, S; Cook, C; Crain, C; Fahrmann, J; Golovko, M; Golovko, S; King, H; Mitchell, B; Paul, D; Ray, K; Santanam, N, 2015)
"Endometriosis was induced surgically by implanting pieces of endometrium in the uterine mesenteries of 50 rats."1.27The effect of treatment on experimentally produced endometrial peritoneal implants. ( Dargenio, R; Golan, A; Winston, RM, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ray, K1
Fahrmann, J1
Mitchell, B1
Paul, D1
King, H1
Crain, C1
Cook, C1
Golovko, M1
Brose, S1
Golovko, S1
Santanam, N1
Shinohara, A1
Kutsukake, M1
Takahashi, M1
Kyo, S1
Tachikawa, E1
Tamura, K1
Acién, P1
Quereda, F1
Campos, A1
Gomez-Torres, MJ1
Velasco, I1
Gutierrez, M1
Ylikorkala, O2
Viinikka, L1
Kauppila, A1
Puolakka, J1
Braun, DP1
Gebel, H1
Rotman, C1
Rana, N1
Dmowski, WP1
Kuo, TM1
Taketani, Y1
Ayabe, T1
Gomibuchi, H1
Yano, T1
Tsutsumi, O1
Mizuno, M1
Golan, A1
Dargenio, R1
Winston, RM1

Trials

3 trials available for indomethacin and Endometrioma

ArticleYear
Use of intraperitoneal interferon alpha-2b therapy after conservative surgery for endometriosis and postoperative medical treatment with depot gonadotropin-releasing hormone analog: a randomized clinical trial.
    Fertility and sterility, 2002, Volume: 78, Issue:4

    Topics: Adult; CA-125 Antigen; CD11 Antigens; Combined Modality Therapy; Delayed-Action Preparations; Endome

2002
Prostaglandins and endometriosis.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1983, Volume: 113

    Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Clinical Trials as Topic; Endometriosis; Epoprostenol; Female

1983
Prostaglandin biosynthesis inhibitors and endometriosis.
    Prostaglandins, 1979, Volume: 18, Issue:4

    Topics: Aspirin; Double-Blind Method; Dysmenorrhea; Endometriosis; Female; Humans; Indomethacin; ortho-Amino

1979

Other Studies

5 other studies available for indomethacin and Endometrioma

ArticleYear
Oxidation-sensitive nociception involved in endometriosis-associated pain.
    Pain, 2015, Volume: 156, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxida

2015
Protease-activated receptor-stimulated interleukin-6 expression in endometriosis-like lesions in an experimental mouse model of endometriosis.
    Journal of pharmacological sciences, 2012, Volume: 119, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Endomet

2012
The development of cytotoxicity in peritoneal macrophages from women with endometriosis.
    Fertility and sterility, 1992, Volume: 57, Issue:6

    Topics: Cytotoxicity, Immunologic; Danazol; Endometriosis; Female; Fertility; Gonadotropin-Releasing Hormone

1992
[Influence of peritoneal fluid with endometriosis on the development of mouse embryos].
    Nihon Sanka Fujinka Gakkai zasshi, 1990, Volume: 42, Issue:10

    Topics: Animals; Ascitic Fluid; Dinoprostone; Embryonic and Fetal Development; Endometriosis; Female; Humans

1990
The effect of treatment on experimentally produced endometrial peritoneal implants.
    Fertility and sterility, 1986, Volume: 46, Issue:5

    Topics: Animals; Danazol; Diathermy; Endometriosis; Female; Fertility; Indomethacin; Microsurgery; Rats; Rat

1986