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indomethacin and Ear Diseases

indomethacin has been researched along with Ear Diseases in 10 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Ear Diseases: Pathological processes of the ear, the hearing, and the equilibrium system of the body.

Research Excerpts

ExcerptRelevanceReference
"Mouse ear edema induced with croton oil was inhibited significantly by dexamethasone and indomethacin at the dose of 10 mg."3.72[Inhibition of dexamethasone, indomethacin and resveratrol on matrix metalloproteinase-9 and the mechanism of inhibition]. ( Bai, JY; Cheng, GF; Li, YT; Shen, F, 2003)
" In this work, ointments made from the same extract and three different excipients (vaseline, lanoline and shea butter (crude and refined)) have been prepared and tested by the method of the croton oil inhibited ear oedema."3.70[Inflammatory ointment from shea butter and hydro-alcoholic extract of Khaya senegalensis barks (Cailcederat)]. ( Ahodikpe, D; Dieng, M; Diop, AB; Lo, I; Ngom, S; Thioune, O, 2000)
"2 microM) and show excellent antiinflammatory potency in the mouse arachidonic acid ear edema model."3.682-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity. ( Batt, DG; Galbraith, W; Harris, RR; Maynard, GD; Petraitis, JJ; Shaw, JE, 1990)
"Oedema was induced by: a) AA (0."1.30Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. ( González, R; Ledón, N; Romay, C, 1998)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's4 (40.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batt, DG1
Maynard, GD1
Petraitis, JJ1
Shaw, JE1
Galbraith, W1
Harris, RR1
Liu, W1
Zhou, J1
Zhang, T1
Zhang, H1
Zhu, H1
Cheng, Y1
Gust, R1
Li, YT1
Shen, F1
Bai, JY1
Cheng, GF1
Thioune, O1
Ahodikpe, D1
Dieng, M1
Diop, AB1
Ngom, S1
Lo, I1
Boulton, P1
Purdy, RA1
Bosch, EP1
Dodick, DW1
Lloret, S1
Moreno, JJ1
Romay, C1
Ledón, N1
González, R1
Włodarski, K1
Luczak, M1
Galus, R1
Włodarski, P1
Bäck, O1
Newton, RC1
Huang, JJ1
Linna, TJ1
Heyworth, T1
Liyanage, SP1

Other Studies

10 other studies available for indomethacin and Ear Diseases

ArticleYear
2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemis

1990
Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine.
    Bioorganic & medicinal chemistry letters, 2012, Oct-01, Volume: 22, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Cell Prol

2012
[Inhibition of dexamethasone, indomethacin and resveratrol on matrix metalloproteinase-9 and the mechanism of inhibition].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Croton Oil; Dexamethason

2003
[Inflammatory ointment from shea butter and hydro-alcoholic extract of Khaya senegalensis barks (Cailcederat)].
    Dakar medical, 2000, Volume: 45, Issue:2

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Croton Oil; Dexamethasone; Disease Mod

2000
Primary and secondary red ear syndrome: implications for treatment.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:2

    Topics: Aged; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Ear

2007
Effects of an anti-inflammatory peptide (antiflammin 2) on cell influx, eicosanoid biosynthesis and oedema formation by arachidonic acid and tetradecanoyl phorbol dermal application.
    Biochemical pharmacology, 1995, Jul-31, Volume: 50, Issue:3

    Topics: Acetylglucosaminidase; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal;

1995
Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Disease Models, Animal; Ear Diseases; Edema; Fo

1998
Local hypertrophic/hyperplastic changes of keratinizing squamous epithelium of pinna induced by concanavalin A and other immunomodulators in mice.
    Folia biologica, 1999, Volume: 45, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Transplantatio

1999
Systemic interleukin I administration suppresses arachidonic acid-induced ear oedema in the mouse.
    The British journal of dermatology, 1989, Volume: 121, Issue:6

    Topics: Animals; Arachidonic Acids; Dose-Response Relationship, Immunologic; Ear Diseases; Edema; Female; In

1989
A pilot survey of hearing loss in patients with rheumatoid arthritis.
    Scandinavian journal of rheumatology, 1972, Volume: 1, Issue:2

    Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Audiometry; Ear; Ear Diseases; Ear, Middle; Hearing

1972