indomethacin has been researched along with Dysmenorrhea in 45 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Dysmenorrhea: Painful menstruation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-two women with primary dysmenorrhea were successfully enrolled in a double-blind, three-way crossover study in which each patient received either ibuprofen (Motrin), indomethacin (Indocin), or a placebo during each of three successive painful menstrual cycles." | 9.05 | Comparative efficacy of ibuprofen, indomethacin, and placebo in the treatment of primary dysmenorrhea. ( Forman, ES; Gookin, KS; Morrison, JC; Vecchio, TJ; Wiser, WL, 1983) |
| "The efficacy of naproxen and indomethacin in the treatment of dysmenorrhea was compared in a double-blind, cross-over study." | 9.04 | Naproxen and indomethacin in the treatment of primary dysmenorrhea. ( Kajanoja, P; Vesanto, T, 1979) |
| "The prostaglandin biosynthesis inhibitors ketoprofen and indomethacin were compared in the treatment of primary dysmenorrhea in a double-blind, cross-over trial involving 23 patients." | 9.04 | The refief of primary dysmenorrhea by ketoprofen and indomethacin. ( Kauppila, A; Puolakka, J; Ylikorkala, O, 1979) |
| "Primary dysmenorrhea is a difficult entity to treat, and therapy is usually directed at relieving symptoms." | 6.65 | Primary dysmenorrhea treated with indomethacin. ( Jennings, JC; Morrison, JC, 1979) |
| "Ibuprofen was free of side effects, but four patients had headaches or peculiar psychic effects on indomethacin." | 5.26 | A clinical trial of indomethacin and ibuprofen in dysmenorrhea. ( Demers, LM; Halbert, DR, 1978) |
| "Forty-two women with primary dysmenorrhea were successfully enrolled in a double-blind, three-way crossover study in which each patient received either ibuprofen (Motrin), indomethacin (Indocin), or a placebo during each of three successive painful menstrual cycles." | 5.05 | Comparative efficacy of ibuprofen, indomethacin, and placebo in the treatment of primary dysmenorrhea. ( Forman, ES; Gookin, KS; Morrison, JC; Vecchio, TJ; Wiser, WL, 1983) |
| "41 women under 30 years of age took part in a prospective, double-blind study to determine whether indomethacin is effective in treating dysmenorrhea." | 5.04 | [Primary dysmenorrhoea treated with indomethacin]. ( Hamann, GO; Laursen, B, 1977) |
| "The efficacy of naproxen and indomethacin in the treatment of dysmenorrhea was compared in a double-blind, cross-over study." | 5.04 | Naproxen and indomethacin in the treatment of primary dysmenorrhea. ( Kajanoja, P; Vesanto, T, 1979) |
| "The prostaglandin biosynthesis inhibitors ketoprofen and indomethacin were compared in the treatment of primary dysmenorrhea in a double-blind, cross-over trial involving 23 patients." | 5.04 | The refief of primary dysmenorrhea by ketoprofen and indomethacin. ( Kauppila, A; Puolakka, J; Ylikorkala, O, 1979) |
| "In a controlled trial the effect of indomethacin was studied in 54 patients with primary dysmenorrhea." | 5.04 | [Symptomatic therapy of primary dysmonorrhea by inhibition of prostaglandin synthesis with indomethacin (author's transl)]. ( Beutnagel, H; Cornely, M; Schönhöfer, PS, 1978) |
| " The analgesic activity was examined against oxytocin-induced dysmenorrhea in mice." | 3.78 | Evaluation of the anti-inflammatory and analgesic properties of individual and combined extracts from Commiphora myrrha, and Boswellia carterii. ( Chen, T; Duan, JA; Gu, W; Hua, Y; Jiang, H; Su, S; Tang, Y; Wang, Y; Zhou, W, 2012) |
| "Indomethacin suppositories were well tolerated and there was no drop-out." | 2.67 | Efficacy of indomethacin suppository in primary dysmenorrhoea. ( al-Waili, NS; Khalaf, ZD, 1990) |
| "Primary dysmenorrhea is a difficult entity to treat, and therapy is usually directed at relieving symptoms." | 2.65 | Primary dysmenorrhea treated with indomethacin. ( Jennings, JC; Morrison, JC, 1979) |
| "Indomethacin treatment raised the incidence of psychic complaints over those with ASA or placebo (P." | 2.65 | Prostaglandin biosynthesis inhibitors and endometriosis. ( Kauppila, A; Puolakka, J; Ylikorkala, O, 1979) |
| "Indomethacin proved to be a valuable agent, and significantly better than aspirin in the treatment of dysmenorrhoea." | 2.64 | Indomethacin in the treatment of primary dysmenorrhoea. ( Kajanoja, P, 1978) |
| "Ibuprofen was free of side effects, but four patients had headaches or peculiar psychic effects on indomethacin." | 1.26 | A clinical trial of indomethacin and ibuprofen in dysmenorrhea. ( Demers, LM; Halbert, DR, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (91.11) | 18.7374 |
| 1990's | 1 (2.22) | 18.2507 |
| 2000's | 2 (4.44) | 29.6817 |
| 2010's | 1 (2.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Su, S | 1 |
| Hua, Y | 1 |
| Wang, Y | 1 |
| Gu, W | 1 |
| Zhou, W | 1 |
| Duan, JA | 1 |
| Jiang, H | 1 |
| Chen, T | 1 |
| Tang, Y | 1 |
| Zhi, LX | 1 |
| Mäkäräinen, L | 1 |
| Ylikorkala, O | 5 |
| Chan, WY | 1 |
| Gookin, KS | 1 |
| Forman, ES | 1 |
| Vecchio, TJ | 1 |
| Wiser, WL | 1 |
| Morrison, JC | 2 |
| Owen, PR | 1 |
| Fraser, IS | 1 |
| Alvin, PE | 1 |
| Litt, IF | 1 |
| Puolakka, J | 3 |
| Kauppila, A | 4 |
| Dingfelder, JR | 1 |
| Székely, J | 1 |
| Benkö, I | 1 |
| Horváth, B | 1 |
| Turay, A | 1 |
| Horváth, S | 1 |
| Szigeti, L | 1 |
| Bolgár, J | 1 |
| Katsulov, A | 1 |
| Mizhorkova, L | 1 |
| Shiels, IA | 1 |
| Whitehouse, MW | 1 |
| Lundström, V | 5 |
| Gréen, K | 2 |
| Svanborg, K | 1 |
| Jacobson, J | 1 |
| Cavalli-Björkman, K | 1 |
| Nilsson, B | 1 |
| Norbeck, M | 1 |
| Hamann, GO | 1 |
| Laursen, B | 1 |
| Kajanoja, P | 2 |
| Jennings, JC | 1 |
| Presl, J | 2 |
| Uzel, R | 1 |
| Pasek, J | 1 |
| Horský, A | 1 |
| Kümmel, M | 1 |
| Kraus, I | 1 |
| Vanata, J | 1 |
| Henzl, MR | 1 |
| Izu, A | 1 |
| Vesanto, T | 1 |
| Elder, MG | 1 |
| Kapadia, L | 1 |
| Nesheim, B | 1 |
| Ladipo, GA | 1 |
| Cornely, M | 1 |
| Beutnagel, H | 1 |
| Schönhöfer, PS | 1 |
| Seifert, B | 1 |
| Liedtke, MP | 1 |
| Halbert, DR | 3 |
| Demers, LM | 3 |
| Wentz, AC | 1 |
| Jones, GS | 1 |
| Wiqvist, N | 1 |
| Darnell Jones, DE | 1 |
| Jones, DE | 1 |
| Fontana, J | 1 |
| al-Waili, NS | 1 |
| Khalaf, ZD | 1 |
| Zahradnik, HP | 1 |
| Breckwoldt, M | 1 |
| Sultan, C | 1 |
| Christensen, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Randomized, Open-label, Controlled Trial to Assess Effectiveness and Safety of Rhea Health Tone® as add-on Therapy for COVID-19 in Hospitalized Adults in Indonesia[NCT04627519] | 85 participants (Actual) | Interventional | 2020-12-09 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for indomethacin and Dysmenorrhea
| Article | Year |
|---|---|
Prostaglandins and nonsteroidal antiinflammatory drugs in dysmenorrhea.
Topics: Anti-Inflammatory Agents; Aspirin; Contraceptives, Oral; Dysmenorrhea; Female; Humans; Ibuprofen; In | 1983 |
Current status of the etiology and management of dysmenorrhea in adolescence.
Topics: Adolescent; Aspirin; Contraceptives, Oral; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans; | 1982 |
Primary dysmenorrhea treatment with prostaglandin inhibitors: a review.
Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Middle Aged; Naproxen; ort | 1981 |
Dysmenorrhea and prostaglandins.
Topics: Contraceptives, Oral, Combined; Dysmenorrhea; Endometrium; Female; Flufenamic Acid; Humans; In Vitro | 1976 |
[Dysmenorrhea in the female adolescent. Clinical, biological and therapeutic data].
Topics: Adolescent; Dinoprost; Dysmenorrhea; Female; France; Humans; Ibuprofen; Indomethacin; ortho-Aminoben | 1986 |
19 trials available for indomethacin and Dysmenorrhea
| Article | Year |
|---|---|
[Randomized controlled study on superficial needling for treatment of primary dysmenorrhea].
Topics: Acupuncture Therapy; Adult; Dysmenorrhea; Female; Humans; Indomethacin; Tablets, Enteric-Coated | 2007 |
Menstrual blood loss in dysmenorrhoea: effects of proquazone and indomethacin.
Topics: Adolescent; Adult; Analgesics; Analgesics, Opioid; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; | 1983 |
Comparative efficacy of ibuprofen, indomethacin, and placebo in the treatment of primary dysmenorrhea.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibup | 1983 |
Prostaglandin synthetase inhibitors in the treatment of primary dysmenorrhea. Outcome trials reviewed.
Topics: Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; | 1984 |
Comparison between fluproquazone and indomethacin in treatment of primary dysmenorrhoea.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Indo | 1981 |
Treatment of primary dysmenorrhea with prostaglandin synthetase inhibitors--a promising therapeutic alternative.
Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double | 1978 |
Prostaglandin synthetase inhibitors and dysmenorrhea. A survey and personal clinical experience.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Ev | 1979 |
[Primary dysmenorrhoea treated with indomethacin].
Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea | 1977 |
Indomethacin in the treatment of primary dysmenorrhoea.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Hum | 1978 |
Primary dysmenorrhea treated with indomethacin.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Indo | 1979 |
[Indometacin therapy for idiopathic dysmenorrhea (author's transl)].
Topics: Adolescent; Adult; Clinical Trials as Topic; Dysmenorrhea; Female; Humans; Indomethacin; Middle Aged | 1979 |
Naproxen and naproxen sodium in dysmenorrhea: development from in vitro inhibition of prostaglandin synthesis to suppression of uterine contractions in women and demonstration of clinical efficacy.
Topics: Animals; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Human | 1979 |
Naproxen and indomethacin in the treatment of primary dysmenorrhea.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Gastroi | 1979 |
Indomethacin in the treatment of primary dysmenorrhoea.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Dysmenorrhea; Fem | 1979 |
[Prostaglandin synthetase inhibitors in treatment of primary dysmenorrhea].
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans | 1977 |
The refief of primary dysmenorrhea by ketoprofen and indomethacin.
Topics: Adolescent; Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Indomethacin; Ketoprofen; Mens | 1979 |
Prostaglandin biosynthesis inhibitors and endometriosis.
Topics: Aspirin; Double-Blind Method; Dysmenorrhea; Endometriosis; Female; Humans; Indomethacin; ortho-Amino | 1979 |
[Symptomatic therapy of primary dysmonorrhea by inhibition of prostaglandin synthesis with indomethacin (author's transl)].
Topics: Adolescent; Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Indomethacin; Nausea; Placebos | 1978 |
Efficacy of indomethacin suppository in primary dysmenorrhoea.
Topics: Administration, Rectal; Adolescent; Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Indome | 1990 |
21 other studies available for indomethacin and Dysmenorrhea
| Article | Year |
|---|---|
Evaluation of the anti-inflammatory and analgesic properties of individual and combined extracts from Commiphora myrrha, and Boswellia carterii.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Boswellia; Carrageenan; Chromatography, Liquid; Commi | 2012 |
Dysmenorrhoea: effective new approaches to a controversial problem.
Topics: Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; M | 1980 |
[Use of indomethacin in treating primary algomenorrhea].
Topics: Adolescent; Adult; Drug Evaluation; Dysmenorrhea; Female; Humans; Indomethacin | 1982 |
[Experience with the treatment of primary dysmenorrhea].
Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Indomethacin; Prostaglandin Antagonists | 1981 |
[Effectiveness of indomethacin in the management of childhood and juvenile primary dysmenorrhea].
Topics: Adolescent; Child; Drug Evaluation; Dysmenorrhea; Female; Humans; Indomethacin; Placebos | 1981 |
[Indomethacin treatment of primary dysmenorrhea].
Topics: Adult; Drug Evaluation; Dysmenorrhea; Female; Humans; Indomethacin; Menstruation; Tablets | 1981 |
Lyprinol: anti-inflammatory and uterine-relaxant activities in rats, with special reference to a model for dysmenorrhoea.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bivalvia; Cyclooxygenase | 2000 |
Endogenous prostaglandins in dysmenorrhea and the effect of prostaglandin synthetase inhibitors (PGSI) on uterine contractility.
Topics: Cyclooxygenase Inhibitors; Dysmenorrhea; Endometrium; Female; Humans; Indomethacin; Menstruation; Mu | 1979 |
[Antagonist of prostaglandin synthesis in the treatment of dysmenorrhea].
Topics: Aspirin; Dysmenorrhea; Female; Humans; Indomethacin; Naproxen; Prostaglandin Antagonists | 1979 |
Drugs for dysmenorrhea.
Topics: Acetaminophen; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Nalbu | 1979 |
Primary dysmenorrhea treated with indomethacin.
Topics: Dysmenorrhea; Female; Humans; Indomethacin | 1977 |
[Uterine prostaglandins and dysmenorrhea].
Topics: Dysmenorrhea; Female; Humans; Indomethacin; Menstruation; Prostaglandins; Prostaglandins E; Prostagl | 1978 |
A clinical trial of indomethacin and ibuprofen in dysmenorrhea.
Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin | 1978 |
Office gynecology: managing dysmenorrhea.
Topics: Contraceptives, Oral; Diuretics; Dysmenorrhea; Family Practice; Female; Gonadal Steroid Hormones; Hu | 1976 |
Prostaglandins, indomethacin and dysmenorrhea.
Topics: Diarrhea; Dysmenorrhea; Female; Humans; Indomethacin; Menstruation; Nausea; Prostaglandins F; Uterin | 1976 |
[Prostaglandins and dysmenorrhea--treatment with indomethacin].
Topics: Dysmenorrhea; Female; Humans; Indomethacin; Prostaglandins | 1976 |
Letter Indomethacin, prostaglandins, and dysmenorrhoea.
Topics: Dysmenorrhea; Female; Humans; Indomethacin; Prostaglandins | 1975 |
Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy.
Topics: Adult; Dysmenorrhea; Endometrium; Female; Humans; Indomethacin; Menstruation; Prostaglandins F; Ther | 1975 |
[Drug therapy of dysmenorrhea].
Topics: Adrenergic beta-Agonists; Adult; Aspirin; Calcium Channel Blockers; Contraceptives, Oral; Dysmenorrh | 1988 |
[Treatment of dysmenorrhea].
Topics: Adolescent; Adult; Age Factors; Aspirin; Dysmenorrhea; Female; Humans; Indomethacin | 1986 |
[Letter: Indomethacin against menstruation pains].
Topics: Dysmenorrhea; Female; Humans; Indomethacin | 1974 |