indomethacin has been researched along with Diseases in Twins in 15 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Diseases in Twins: Disorders affecting TWINS, one or both, at any age.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin was administered to suppress premature uterine contractions in a twin pregnancy from the 27th until the 32nd week of pregnancy." | 7.67 | Patent ductus arteriosus after prolonged treatment with indomethacin during pregnancy: case report. ( Abramovici, H; Atad, J; Lissak, A; Rofe, A, 1987) |
| "Two twins born to a mother who had been treated with Indomethacin at the end of pregnancy presented with variable but transitory hypoxemia." | 7.66 | [Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)]. ( Boulley, AM; Dehan, M; Gabilan, JC; Hernandorena, X; Laudignon, N; Lhermitte, C; Ropert, JC; Vial, M, 1980) |
| "We report oligohydramnios and renal dysgenesis in one of identical twins, which might have resulted from in utero exposure to early, prolonged high-dose indomethacin." | 3.68 | Renal dysgenesis in a monozygotic twin: association with in utero exposure to indomethacin. ( Kaplan, BS; Kaplan, P; Restaino, I; Roberts, N; Rosenberg, HK; Witzleben, C, 1991) |
| "Indomethacin was given for the treatment of preterm labor in a twin pregnancy at a dosage of 200 mg/day for 7 days beginning at 34 weeks and 5 days' gestation." | 3.68 | Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation. ( Ayres, NA; Hallak, M; Moise, KJ; Reiter, AA, 1991) |
| "Indomethacin was administered to suppress premature uterine contractions in a twin pregnancy from the 27th until the 32nd week of pregnancy." | 3.67 | Patent ductus arteriosus after prolonged treatment with indomethacin during pregnancy: case report. ( Abramovici, H; Atad, J; Lissak, A; Rofe, A, 1987) |
| "Two twins born to a mother who had been treated with Indomethacin at the end of pregnancy presented with variable but transitory hypoxemia." | 3.66 | [Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)]. ( Boulley, AM; Dehan, M; Gabilan, JC; Hernandorena, X; Laudignon, N; Lhermitte, C; Ropert, JC; Vial, M, 1980) |
| "Forty patients with intact membranes in preterm labor at 23 to 34 weeks' gestation were randomized to receive either intravenous ritodrine or oral indomethacin as the first-line tocolytic agent." | 2.67 | Randomized comparative trial of indomethacin and ritodrine for the long-term treatment of preterm labor. ( Besinger, RE; Johnson, TR; Keyes, WG; Niebyl, JR, 1991) |
| "When pregnancy is continued after death of one fetus in monochorionic twin pregnancy, the surviving fetus sometimes exhibits intrauterine death or brain damage." | 1.30 | Hysterotomy and selective delivery of an intrauterine dead fetus to prevent intrauterine death or brain damage of the surviving fetus in monochorionic twin pregnancy. ( Ito, T; Kadowaki, K; Makio, A; Nagata, N; Takahashi, H; Terakawa, N, 1997) |
| "The incidence and evolution of patent ductus arteriosus (PDA) was evaluated in twins and preterm singletons with birth weight less than or equal to 1750 g admitted to our Department in 1987 for respiratory distress syndrome (RDS)." | 1.28 | Does the respiratory distress syndrome in twins and singletons run different risks of persistent ductus arteriosus? ( Foti, P; Milanesi, O; Stellin, G; Trevisanuto, D; Zambon, P; Zanardo, V, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tarcan, A | 1 |
| Gürakan, B | 1 |
| Yildirim, S | 1 |
| Ozkiraz, S | 1 |
| Bilezikçi, B | 1 |
| Mogilner, BM | 1 |
| Ashkenazy, M | 1 |
| Borenstein, R | 1 |
| Lancet, M | 1 |
| Boulley, AM | 1 |
| Dehan, M | 1 |
| Vial, M | 1 |
| Hernandorena, X | 1 |
| Ropert, JC | 1 |
| Laudignon, N | 1 |
| Lhermitte, C | 1 |
| Gabilan, JC | 1 |
| Oriot, D | 1 |
| Boussemart, T | 1 |
| Berthier, M | 1 |
| Bonneau, D | 1 |
| Coisne, D | 1 |
| Murray, HG | 1 |
| Stone, PR | 1 |
| Strand, L | 1 |
| Flower, J | 1 |
| Takahashi, Y | 1 |
| Harada, K | 1 |
| Ishida, A | 1 |
| Tanaka, T | 1 |
| Tsuda, A | 1 |
| Takada, G | 1 |
| Ito, T | 1 |
| Kadowaki, K | 1 |
| Takahashi, H | 1 |
| Nagata, N | 1 |
| Makio, A | 1 |
| Terakawa, N | 1 |
| Kumar, R | 1 |
| Sharma, YP | 1 |
| Gupta, I | 1 |
| Restaino, I | 1 |
| Kaplan, BS | 1 |
| Kaplan, P | 1 |
| Rosenberg, HK | 1 |
| Witzleben, C | 1 |
| Roberts, N | 1 |
| Hallak, M | 1 |
| Reiter, AA | 1 |
| Ayres, NA | 1 |
| Moise, KJ | 1 |
| Besinger, RE | 1 |
| Niebyl, JR | 1 |
| Keyes, WG | 1 |
| Johnson, TR | 1 |
| Haddad, J | 2 |
| Messer, J | 2 |
| Casanova, R | 1 |
| Simeoni, U | 2 |
| Willard, D | 2 |
| Weisburd, P | 1 |
| Zanardo, V | 1 |
| Foti, P | 1 |
| Trevisanuto, D | 1 |
| Zambon, P | 1 |
| Stellin, G | 1 |
| Milanesi, O | 1 |
| Atad, J | 1 |
| Lissak, A | 1 |
| Rofe, A | 1 |
| Abramovici, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vaginal Indomethacin Versus Oral Nifedipine for Preterm Labor; a Randomized Controlled Trial[NCT04404686] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2020-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for indomethacin and Diseases in Twins
| Article | Year |
|---|---|
Randomized comparative trial of indomethacin and ritodrine for the long-term treatment of preterm labor.
Topics: Amniotic Fluid; Diseases in Twins; Female; Fetal Diseases; Humans; Hypertension, Pulmonary; Indometh | 1991 |
14 other studies available for indomethacin and Diseases in Twins
| Article | Year |
|---|---|
Persistent pulmonary hypertension in a premature newborn after 16 hours of antenatal indomethacin exposure.
Topics: Adult; Constriction, Pathologic; Diseases in Twins; Ductus Arteriosus; Female; Gestational Age; Huma | 2004 |
Hydrops fetalis caused by maternal indomethacin treatment.
Topics: Adult; Diseases in Twins; Edema; Female; Heart Defects, Congenital; Humans; Indomethacin; Infant, Ne | 1982 |
[Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)].
Topics: Adult; Cyanosis; Diseases in Twins; Female; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, | 1980 |
Paradoxical effect of inhaled nitric oxide in a newborn with pulmonary hypertension.
Topics: Administration, Inhalation; Diseases in Twins; Female; Humans; Hypoxia; Indomethacin; Infant, Newbor | 1993 |
Fetal pleural effusion following maternal indomethacin therapy.
Topics: Adult; Cesarean Section; Diseases in Twins; Female; Fetal Diseases; Humans; Indomethacin; Pleural Ef | 1993 |
Doppler echocardiographic findings of indomethacin-induced occlusion of the fetal ductus arteriosus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Cyclooxygenase Inhibitors; Dilatat | 1996 |
Hysterotomy and selective delivery of an intrauterine dead fetus to prevent intrauterine death or brain damage of the surviving fetus in monochorionic twin pregnancy.
Topics: Adult; Delivery, Obstetric; Diseases in Twins; Female; Fetal Death; Gestational Age; Humans; Indomet | 1997 |
Tricuspid regurgitation in a pair of twins at birth secondary to antenatal indomethacin.
Topics: Diseases in Twins; Female; Fetal Diseases; Humans; Indomethacin; Polyhydramnios; Pregnancy; Tocolyti | 2001 |
Renal dysgenesis in a monozygotic twin: association with in utero exposure to indomethacin.
Topics: Adult; Diseases in Twins; Female; Humans; Indomethacin; Infant, Newborn; Kidney; Maternal-Fetal Exch | 1991 |
Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation.
Topics: Abnormalities, Drug-Induced; Adult; Diseases in Twins; Drug Monitoring; Ductus Arteriosus; Female; F | 1991 |
Indomethacin and ischemic brain injury in neonates.
Topics: Brain Ischemia; Diseases in Twins; Encephalomalacia; Female; Humans; Indomethacin; Infant, Newborn; | 1990 |
Neonatal renal dysfunction and intrauterine exposure to prostaglandin synthesis inhibitors.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Cesarean Section; Cyclo | 1989 |
Does the respiratory distress syndrome in twins and singletons run different risks of persistent ductus arteriosus?
Topics: Diseases in Twins; Ductus Arteriosus, Patent; Echocardiography; Humans; Indomethacin; Infant, Low Bi | 1989 |
Patent ductus arteriosus after prolonged treatment with indomethacin during pregnancy: case report.
Topics: Adult; Diseases in Twins; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; | 1987 |