Page last updated: 2024-10-29

indomethacin and Diabetic Retinopathy

indomethacin has been researched along with Diabetic Retinopathy in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
" With a highly extended half-life of ∼40 h in rabbit eyes following intravitreal administration, the bicyclic peptides are promising novel agents for the treatment of diabetic retinopathy and diabetic macular edema."3.88Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema. ( Barbeaux, P; Bennett, G; Feyen, JHM; Harrison, H; Hu, TT; Le Floch, F; Pavan, S; Stace, C; Teufel, DP; Van Bergen, T; van Rietschoten, K; Vanhove, M; Vermassen, E, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Teufel, DP1
Bennett, G1
Harrison, H1
van Rietschoten, K1
Pavan, S1
Stace, C1
Le Floch, F1
Van Bergen, T1
Vermassen, E1
Barbeaux, P1
Hu, TT1
Feyen, JHM1
Vanhove, M1
Alpar, JJ1
Watanabe, J1
Umeda, F1
Wasada, T1
Ibayashi, H1
Waitzman, MB2
Colley, AM1
Nardelli-Olkowska, K1

Reviews

1 review available for indomethacin and Diabetic Retinopathy

ArticleYear
Metabolic approaches to studies on diabetic microangiopathy.
    Diabetes, 1977, Volume: 26, Issue:5

    Topics: Blood Platelets; Collagen; Cyclic AMP; Diabetic Angiopathies; Diabetic Retinopathy; Drug Interaction

1977

Trials

1 trial available for indomethacin and Diabetic Retinopathy

ArticleYear
Cataract extraction and diabetic retinopathy.
    Journal - American Intra-Ocular Implant Society, 1984,Fall, Volume: 10, Issue:4

    Topics: Aged; Cataract Extraction; Diabetic Retinopathy; Evaluation Studies as Topic; Eye Diseases; Female;

1984

Other Studies

3 other studies available for indomethacin and Diabetic Retinopathy

ArticleYear
Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema.
    Journal of medicinal chemistry, 2018, 04-12, Volume: 61, Issue:7

    Topics: Animals; Bradykinin; Bridged Bicyclo Compounds; Diabetes Complications; Diabetic Retinopathy; Edema;

2018
Effect of prostaglandin synthetase inhibitors on platelet aggregation and thromboxane production in diabetes mellitus.
    The Tohoku journal of experimental medicine, 1984, Volume: 144, Issue:2

    Topics: Adult; Diabetes Mellitus; Diabetic Retinopathy; Female; Humans; Imidazoles; Indomethacin; Male; Midd

1984
Prostaglandins and the eye: rapid transition from basic to applied and implications for expanded clinical consideration.
    Metabolic, pediatric, and systemic ophthalmology, 1982, Volume: 6, Issue:1

    Topics: Animals; Diabetic Retinopathy; Dogs; Edema; Eye Diseases; Glaucoma; Humans; Indomethacin; Norepineph

1982