indomethacin has been researched along with Diabetic Glomerulosclerosis in 17 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To define the importance of renal prostaglandins in nephrogenic diabetes insipidus (NDI), diuresis and the urinary excretion of PGE2 and PGF2 alpha were studied in a patient with NDI before and during inhibition of endogenous prostaglandin synthesis with either indomethacin (IND) or acetyl-salicylic acid (ASA)." | 7.67 | Comparative therapeutic benefit of indomethacin, hydrochlorothiazide, and acetyl-salicylic acid in a patient with nephrogenic diabetes insipidus. ( Favre, L; Jörg, J; Vallotton, MB; Vierhapper, H; Waldhäusl, W, 1984) |
| " In nondiabetic rats, stimulation of the endothelium by locally administered ACh or bradykinin-induced transient renal hyperemia." | 3.74 | In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes. ( Edgley, AJ; Evans, RG; Parkington, HC; Skordilis, C; Tare, M, 2008) |
| "To define the importance of renal prostaglandins in nephrogenic diabetes insipidus (NDI), diuresis and the urinary excretion of PGE2 and PGF2 alpha were studied in a patient with NDI before and during inhibition of endogenous prostaglandin synthesis with either indomethacin (IND) or acetyl-salicylic acid (ASA)." | 3.67 | Comparative therapeutic benefit of indomethacin, hydrochlorothiazide, and acetyl-salicylic acid in a patient with nephrogenic diabetes insipidus. ( Favre, L; Jörg, J; Vallotton, MB; Vierhapper, H; Waldhäusl, W, 1984) |
| "Indomethacin treatment induced a significant reduction in urinary prostaglandin E2 excretion (73%) (2p less than 0." | 2.66 | Elevated urinary prostaglandin excretion and the effect of indomethacin on renal function in incipient diabetic nephropathy. ( Hommel, E; Mathiesen, ER; Olsen, UB; Parving, HH, 1988) |
| "Indomethacin treatment induced a significant reduction in urinary prostaglandin E2 excretion (73%, p less than 0." | 2.66 | Effects of indomethacin on kidney function in type 1 (insulin-dependent) diabetic patients with nephropathy. ( Arnold-Larsen, S; Edsberg, B; Hommel, E; Mathiesen, E; Olsen, UB; Parving, HH, 1987) |
| "Reduction of proteinuria is a prerequisite for successful long-term renoprotection." | 1.31 | Role of patient factors in therapy resistance to antiproteinuric intervention in nondiabetic and diabetic nephropathy. ( Andersen, S; Bos, H; De Jong, PE; De Zeeuw, D; Navis, G; Parving, HH; Rossing, P, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edgley, AJ | 1 |
| Tare, M | 1 |
| Evans, RG | 1 |
| Skordilis, C | 1 |
| Parkington, HC | 1 |
| Kamata, K | 1 |
| Hosokawa, M | 1 |
| Matsumoto, T | 1 |
| Kobayashi, T | 1 |
| Jacob, CK | 1 |
| Date, A | 1 |
| Kirubakaran, MG | 1 |
| Shastry, JC | 1 |
| Johny, KV | 1 |
| Vierhapper, H | 1 |
| Jörg, J | 1 |
| Favre, L | 1 |
| Vallotton, MB | 1 |
| Waldhäusl, W | 1 |
| Andersen, O | 1 |
| Jacobsen, BB | 1 |
| Stögmann, W | 1 |
| Bohrn, E | 1 |
| Blackshear, JL | 1 |
| Davidman, M | 1 |
| Stillman, MT | 1 |
| Rudberg, S | 1 |
| Sätterström, G | 1 |
| Dahlqvist, R | 1 |
| Dahlquist, G | 1 |
| Man'kovskiĭ, BN | 1 |
| Tadzhieva, DCh | 1 |
| Bos, H | 1 |
| Andersen, S | 1 |
| Rossing, P | 1 |
| De Zeeuw, D | 1 |
| Parving, HH | 3 |
| De Jong, PE | 1 |
| Navis, G | 1 |
| McCormack, AJ | 1 |
| Hak, LJ | 1 |
| Finn, WF | 1 |
| Bank, N | 1 |
| Lahorra, MA | 1 |
| Aynedjian, HS | 1 |
| Schlondorff, D | 1 |
| Mathiesen, ER | 1 |
| Hommel, E | 2 |
| Olsen, UB | 2 |
| Hara, S | 1 |
| Mimura, N | 1 |
| Tourniaire, J | 1 |
| Bajard, L | 1 |
| Harfouch, M | 1 |
| Rebattu, B | 1 |
| Garrel, D | 1 |
| van den Berg, BW | 1 |
| Kruseman, AC | 1 |
| van Geel, JL | 1 |
| Cornelissen, P | 1 |
| Mulder, AW | 1 |
| Mathiesen, E | 1 |
| Arnold-Larsen, S | 1 |
| Edsberg, B | 1 |
3 trials available for indomethacin and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Indomethacin but not metoprolol reduces exercise-induced albumin excretion rate in type 1 diabetic patients with microalbuminuria.
Topics: Adult; Albuminuria; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies | 1993 |
Elevated urinary prostaglandin excretion and the effect of indomethacin on renal function in incipient diabetic nephropathy.
Topics: Adult; Albuminuria; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dinoprostone; Female; Glomeru | 1988 |
Effects of indomethacin on kidney function in type 1 (insulin-dependent) diabetic patients with nephropathy.
Topics: Adult; Albuminuria; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dinoprostone; Double-Blind Me | 1987 |
14 other studies available for indomethacin and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes.
Topics: Acetylcholine; Anesthesia; Animals; Animals, Outbred Strains; Biological Factors; Blood Pressure; Br | 2008 |
Altered arachidonic acid-mediated responses in the perfused kidney of the streptozotocin-induced diabetic rat.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Diabetes M | 2006 |
Effect of indomethacin on the proteinuria of diabetic nephropathy.
Topics: Adult; Diabetic Nephropathies; Female; Follow-Up Studies; Humans; Indomethacin; Kidney; Male; Middle | 1984 |
Comparative therapeutic benefit of indomethacin, hydrochlorothiazide, and acetyl-salicylic acid in a patient with nephrogenic diabetes insipidus.
Topics: Adolescent; Aspirin; Diabetes Insipidus; Diabetic Nephropathies; Dinoprost; Dinoprostone; Diuresis; | 1984 |
The renin-aldosterone system in nephrogenic diabetes insipidus and the influence of hydrochlorothiazide and indomethacin.
Topics: Adolescent; Adult; Diabetes Insipidus; Diabetic Nephropathies; Drug Therapy, Combination; Female; Hu | 1983 |
[Inhibition of prostaglandin synthesis during the therapy of nephrogenic diabetes insipidus].
Topics: Diabetes Insipidus; Diabetic Nephropathies; Fluid Therapy; Humans; Indomethacin; Infant; Male; Prost | 1984 |
Identification of risk for renal insufficiency from nonsteroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adult; Age Factors; Aged; Anti-Inflammatory Agents; Arteriosclerosis; Blood Ure | 1983 |
[A drug test with indomethacin in the diagnosis of subclinical forms of diabetic nephropathy].
Topics: Adolescent; Adult; Albuminuria; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diabetes M | 1999 |
Role of patient factors in therapy resistance to antiproteinuric intervention in nondiabetic and diabetic nephropathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Diabetic Nephropa | 2000 |
The effect of aldose reductase inhibition and dietary protein restriction on renal function in experimental diabetes mellitus.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Protei | 1991 |
Vasoregulatory hormones and the hyperfiltration of diabetes.
Topics: Algorithms; Angiotensin II; Animals; Aprotinin; Bradykinin; Diabetic Nephropathies; Dinoprostone; Gl | 1988 |
[Glomerular diseases secondary to diabetes mellitus].
Topics: Adult; Diabetic Nephropathies; Dipyridamole; Humans; Hypertension, Renal; Indomethacin; Kidney Trans | 1988 |
[Restoration of insulin sensitivity after correction of hypokalemia due to chronic tubulopathy in a diabetic patient].
Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glucose Clamp Technique; Humans; H | 1988 |
Effect of short-term inhibition of prostaglandin synthesis on glomerular filtration rate and microalbuminuria in patients with incipient diabetic nephropathy.
Topics: Adult; Aged; Albuminuria; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glomerular Filt | 1988 |