indomethacin has been researched along with Diabetes, Gestational in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Diabetes, Gestational: Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glyburide, a drug used to treat gestational diabetes has previously been shown not to be measurable in fetal blood, and to be transferred from the fetal to the maternal circulation against a concentration gradient." | 1.35 | Investigating the potential role of multi-drug resistance protein (MRP) transporters in fetal to maternal glyburide efflux in the human placenta. ( Anger, G; Gedeon, C; Koren, G; Lubetsky, A; Miller, MP, 2008) |
| "Placental vessels of women with gestational diabetes were found to undergo a significantly larger contraction than normal vessels when exposed to posthypoxic reoxygenation or micromolar concentrations of hydrogen peroxide." | 1.29 | Gestational diabetes alters human placental vascular responses to changes in oxygen tension. ( Figueroa, R; Omar, HA; Tejani, N; Wolin, MS, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gedeon, C | 1 |
| Anger, G | 1 |
| Lubetsky, A | 1 |
| Miller, MP | 1 |
| Koren, G | 1 |
| Figueroa, R | 2 |
| Omar, HA | 1 |
| Tejani, N | 2 |
| Wolin, MS | 2 |
| Knock, GA | 1 |
| McCarthy, AL | 1 |
| Lowy, C | 1 |
| Poston, L | 1 |
| Clode, N | 1 |
| Mendonça, E | 1 |
| Stone, R | 1 |
| Soares, L | 1 |
| Cardoso, C | 1 |
| Graça, LM | 1 |
| Coelho Rosa, F | 1 |
| Martinez, E | 1 |
| Fayngersh, RP | 1 |
| Mohazzab-H, KM | 1 |
5 other studies available for indomethacin and Diabetes, Gestational
| Article | Year |
|---|---|
Investigating the potential role of multi-drug resistance protein (MRP) transporters in fetal to maternal glyburide efflux in the human placenta.
Topics: Adult; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Indomethacin; Male; Ma | 2008 |
Gestational diabetes alters human placental vascular responses to changes in oxygen tension.
Topics: Adolescent; Adult; Arteries; Cell Hypoxia; Diabetes, Gestational; Dose-Response Relationship, Drug; | 1993 |
Association of gestational diabetes with abnormal maternal vascular endothelial function.
Topics: Acetylcholine; Arginine; Diabetes, Gestational; Endothelium, Vascular; Enzyme Inhibitors; Female; Hu | 1997 |
Bartter's syndrome and pregnancy.
Topics: Adult; Apgar Score; Cesarean Section; Creatinine; Diabetes, Gestational; Diuresis; Female; Humans; I | 1999 |
Alterations in relaxation to lactate and H(2)O(2) in human placental vessels from gestational diabetic pregnancies.
Topics: Adolescent; Adult; Arachidonic Acid; Colforsin; Diabetes, Gestational; Female; Humans; Hydrogen Pero | 2000 |