Page last updated: 2024-10-29

indomethacin and Dermatitis

indomethacin has been researched along with Dermatitis in 30 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Dermatitis: Any inflammation of the skin.

Research Excerpts

ExcerptRelevanceReference
"The effects of topical indomethacin and clobetasol propionate on erythema and oedema following low-dose cryotherapy to normal skin were examined using a single-blind technique."5.08The effects of topical indomethacin and clobetasol propionate on post-cryotherapy inflammation. ( Humphreys, F; Spiro, J, 1995)
" Petroleum ether, chloroform and chloroform-methanol extracts inhibited the Croton oil-induced ear dermatitis in mice."3.79Steroids with anti-inflammatory activity from Vernonia nigritiana Oliv. & Hiern. ( De Tommasi, N; Della Loggia, R; Merfort, I; Pelin, M; Sanogo, R; Severino, L; Sosa, S; Tubaro, A; Vassallo, A, 2013)
"Petroleum ether, chloroform and methanol extracts were obtained for herbal medicines and then extracts were tested on Croton oil-induced ear dermatitis model in mice."3.75Screening of the topical anti-inflammatory activity of the bark of Acacia cornigera Willdenow, Byrsonima crassifolia Kunth, Sweetia panamensis Yakovlev and the leaves of Sphagneticola trilobata Hitchcock. ( Balick, MJ; Della Loggia, R; Giangaspero, A; Maldini, M; Montoro, P; Pizza, C; Sosa, S, 2009)
"The topical anti-inflammatory activity of a germacrane derivative [1,4-dihydroxy-germacra-5E-10(14)-diene; DHGD] isolated from Achillea pannonica Scheele (Asteraceae) was investigated employing the Croton oil-induced dermatitis in the mouse ear."3.71Topical anti-inflammatory activity of a new germacrane derivative from Achillea pannonica. ( Della Loggia, R; Glasl, S; Jurenitsch, J; Kastner, U; Sosa, S; Tubaro, A, 2001)
" All these compounds proved to be effective against 12-O-tetradecanoylphorbol-13-acetate-induced ear edema in mice, although lacking activity against arachidonic acid-induced edema."3.70A glycosyl analogue of diacylglycerol and other antiinflammatory constituents from Inula viscosa. ( Gil, I; Giner, RM; Gómez, C; Máñez, S; Recio, MC; Ríos, JL; Waterman, PG, 1999)
"2 microM) and show excellent antiinflammatory potency in the mouse arachidonic acid ear edema model."3.682-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity. ( Batt, DG; Galbraith, W; Harris, RR; Maynard, GD; Petraitis, JJ; Shaw, JE, 1990)
"Interstitial fluid pressure (Pif) was measured in skin of pentobarbital-anesthetized rats during anaphylaxis toward dextran and after subdermal injection of histamine by using sharpened glass capillaries (tip diam 5-7 microns) connected to a servo-controlled counterpressure system."3.68Increased negativity of interstitial fluid pressure during the onset stage of inflammatory edema in rat skin. ( Reed, RK; Rodt, SA, 1991)
"Indomethacin did not suppress acceleration of repopulation."1.30Modulation of accelerated repopulation in mouse skin during daily irradiation. ( Heasman, F; Shirazi, A; Trott, KR, 1999)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199011 (36.67)18.7374
1990's10 (33.33)18.2507
2000's4 (13.33)29.6817
2010's5 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wright, SW1
Harris, RR3
Collins, RJ2
Corbett, RL1
Green, AM1
Wadman, EA1
Batt, DG3
Maynard, GD1
Petraitis, JJ1
Shaw, JE1
Galbraith, W1
Máñez, S1
Recio, MC1
Gil, I1
Gómez, C1
Giner, RM1
Waterman, PG1
Ríos, JL1
Soeberdt, M1
Molenveld, P1
Storcken, RP1
Bouzanne des Mazery, R1
Sterk, GJ1
Autar, R1
Bolster, MG1
Wagner, C1
Aerts, SN1
van Holst, FR1
Wegert, A1
Tangherlini, G1
Frehland, B1
Schepmann, D1
Metze, D1
Lotts, T1
Knie, U1
Lin, KY1
Huang, TY1
Lai, CC1
Ständer, S1
Wünsch, B1
Abels, C1
Joseph, LB1
Composto, GM1
Perez, RM1
Kim, HD1
Casillas, RP1
Heindel, ND1
Young, SC1
Lacey, CJ1
Saxena, J1
Guillon, CD1
Croutch, CR1
Laskin, JD1
Heck, DE1
Vassallo, A1
De Tommasi, N1
Merfort, I1
Sanogo, R1
Severino, L1
Pelin, M1
Della Loggia, R3
Tubaro, A2
Sosa, S3
Limón, D1
Amirthalingam, E1
Rodrigues, M1
Halbaut, L1
Andrade, B1
Garduño-Ramírez, ML1
Amabilino, DB1
Pérez-García, L1
Calpena, AC1
Maldini, M1
Montoro, P1
Giangaspero, A1
Balick, MJ1
Pizza, C1
Iinuma, K1
Sato, T1
Akimoto, N1
Kurihara, H1
Ito, A1
Thut, PD1
Hermanstyne, TO1
Flake, NM1
Gold, MS1
Gordon, JS1
Wolanin, PM1
Gonzalez, AV1
Fela, DA1
Sarngadharan, G1
Rouzard, K1
Perez, E1
Stock, JB1
Stock, MB1
Greaves, MW1
Woodward, DF1
Raval, P1
Pipkin, MA1
Owen, DA1
Humphreys, F2
Spiro, J1
Trott, KR1
Shirazi, A1
Heasman, F1
Kastner, U1
Glasl, S1
Jurenitsch, J1
Ljunggren, B1
Weirich, EG1
Longauer, JK1
Kirkwood, AH1
Honmura, A1
Yanase, M1
Obata, J1
Haruki, E1
Foster, AP1
Cunningham, FM1
Lees, P1
Reed, RK1
Rodt, SA1
Shuster, S1
Mackin, WM1
Rakich, SM1
Bruin, EM1
Ackerman, NR1
Sharpe, RJ1
Margolis, RJ1
Askari, M1
Amento, EP1
Granstein, RD1
Swerlick, RA1
Yancey, KB1
Lawley, TJ1
Samsonov, VA1
Timoshin, GG1
Starkov, IV1
Barbier, A1
Planchenault, C1
Vernhet, C1
Brelière, JC1
Szarmach, H1
Poniecka, H1
Moore, DS1
Nally, FF1
Kossakowska, M1
Michalak, E1
Chwaliński, S1

Reviews

1 review available for indomethacin and Dermatitis

ArticleYear
[Prostaglandins, leukotrienes, anti-inflammatory substances and their importance in inflammatory reactions of the skin].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1982, Volume: 33, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Dermatitis; Drug Interaction

1982

Trials

1 trial available for indomethacin and Dermatitis

ArticleYear
The effects of topical indomethacin and clobetasol propionate on post-cryotherapy inflammation.
    The British journal of dermatology, 1995, Volume: 132, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Child; Clobetasol; Cryotherapy; Dermatitis; Double-Blind

1995

Other Studies

28 other studies available for indomethacin and Dermatitis

ArticleYear
Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity.
    Journal of medicinal chemistry, 1992, Aug-21, Volume: 35, Issue:17

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Calcimycin; Cyclooxyge

1992
2-substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemis

1990
A glycosyl analogue of diacylglycerol and other antiinflammatory constituents from Inula viscosa.
    Journal of natural products, 1999, Volume: 62, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

1999
Design and Synthesis of Enantiomerically Pure Decahydroquinoxalines as Potent and Selective κ-Opioid Receptor Agonists with Anti-Inflammatory Activity in Vivo.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Dermatitis; Drug Design; Guinea Pigs; Humans; Male; Mice; Mice, I

2017
Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug.
    Toxicology letters, 2018, Sep-01, Volume: 293

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Degranulation; Chemical Warfare Agents; Choli

2018
Steroids with anti-inflammatory activity from Vernonia nigritiana Oliv. & Hiern.
    Phytochemistry, 2013, Volume: 96

    Topics: Animals; Anti-Inflammatory Agents; Croton Oil; Dermatitis; Ear; Glycosides; Hydrocortisone; Indometh

2013
Novel nanostructured supramolecular hydrogels for the topical delivery of anionic drugs.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 96

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis; Drug Compou

2015
Screening of the topical anti-inflammatory activity of the bark of Acacia cornigera Willdenow, Byrsonima crassifolia Kunth, Sweetia panamensis Yakovlev and the leaves of Sphagneticola trilobata Hitchcock.
    Journal of ethnopharmacology, 2009, Apr-21, Volume: 122, Issue:3

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Asteraceae; Croton Oil; Dermatitis; Faba

2009
Induction of inflammatory reactions by lipopolysaccharide in hamster sebaceous glands and pilosebaceous units in vivo and in vitro.
    Experimental dermatology, 2010, Volume: 19, Issue:12

    Topics: Animals; Cells, Cultured; Cricetinae; Cyclooxygenase 2; Dermatitis; Dinoprost; Ear Auricle; Epidermi

2010
An operant conditioning model to assess changes in feeding behavior associated with temporomandibular joint inflammation in the rat.
    Journal of orofacial pain, 2007,Winter, Volume: 21, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; B

2007
Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:3

    Topics: Acetylcysteine; Administration, Topical; Animals; Animals, Outbred Strains; Anti-Inflammatory Agents

2008
Re-evaluation of the effect of non-steroidal anti-inflammatory agents on u.v.-induced cutaneous inflammation.
    Agents and actions, 1981, Volume: 11, Issue:6-7

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Body Temperature; Dermatitis

1981
Modulation of accelerated repopulation in mouse skin during daily irradiation.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1999, Volume: 50, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Dermatitis; Epidermal Cells; Epider

1999
Topical anti-inflammatory activity of a new germacrane derivative from Achillea pannonica.
    Planta medica, 2001, Volume: 67, Issue:7

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asteraceae; Croton Oil; D

2001
Inhibition of ultraviolet and phototoxic dermatitis in the mouse.
    Acta dermato-venereologica, 1978, Volume: 58, Issue:4

    Topics: Animals; Aspirin; Betamethasone; Chlorpromazine; Dermatitis; Female; Indomethacin; Mice; Photosensit

1978
Dermatopharmacology of salicylic acid. III. Topical contra-inflammatory effect of salicylic acid and other drugs in animal experiments.
    Dermatologica, 1976, Volume: 152, Issue:2

    Topics: Administration, Topical; Animals; Aspirin; Bufexamac; Dermatitis; Flumethasone; Fluocinolone Acetoni

1976
Therapeutic effect of Ga-Al-As diode laser irradiation on experimentally induced inflammation in rats.
    Lasers in surgery and medicine, 1992, Volume: 12, Issue:4

    Topics: Aluminum; Animals; Arsenic; Blood Proteins; Body Water; Capillary Permeability; Carrageenan; Dermati

1992
Inflammatory effects of platelet activating factor (PAF) in equine skin.
    Equine veterinary journal, 1992, Volume: 24, Issue:3

    Topics: Animals; Capillary Permeability; Chlorpheniramine; Dermatitis; Dinoprostone; Dose-Response Relations

1992
Increased negativity of interstitial fluid pressure during the onset stage of inflammatory edema in rat skin.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 2

    Topics: Anaphylaxis; Animals; Capillary Permeability; Cyproheptadine; Dermatitis; Dextrans; Edema; Female; H

1991
The effect of indomethacin on the kinetics of histamine, 48/80 and antigen wealing.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:2

    Topics: Adult; Animals; Cyclooxygenase Inhibitors; Dermatitis; Dose-Response Relationship, Drug; Female; Hal

1990
Cellular and biochemical characterization of the anti-inflammatory effects of DuP 654 in the arachidonic acid murine skin inflammation model.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1990, Volume: 3, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arac

1990
Induction of dermal and subcutaneous inflammation by recombinant cachectin/tumor necrosis factor (TNF alpha) in the mouse.
    The Journal of investigative dermatology, 1988, Volume: 91, Issue:4

    Topics: Acute Disease; Animals; Dermatitis; Drug Administration Schedule; Female; Indomethacin; Injections,

1988
A direct in vivo comparison of the inflammatory properties of human C5a and C5a des Arg in human skin.
    Journal of immunology (Baltimore, Md. : 1950), 1988, Apr-01, Volume: 140, Issue:7

    Topics: Aspirin; Biopsy, Needle; Complement C5; Complement C5a; Complement C5a, des-Arginine; Dermatitis; Hu

1988
[Indomethacin ointment in the treatment of various dermatoses].
    Vestnik dermatologii i venerologii, 1988, Issue:4

    Topics: Adult; Dermatitis; Female; Humans; Indomethacin; Male; Middle Aged; Ointments; Psoriasis

1988
Dermatosis in magnesium-deficient hairless rats: effects of steroidal and non-steroidal anti-inflammatory drugs.
    Agents and actions, 1986, Volume: 17, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents; Dermatitis; Dexamethasone; Diet; Indomethacin; Magnesium; Magnesi

1986
[Metindol--Indometacinum--"POLFA" in the treatment of various allergic skin diseases].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1972, Jun-15, Volume: 47, Issue:12

    Topics: Adolescent; Adult; Aged; Dermatitis; Dermatitis, Exfoliative; Drug Eruptions; Eczema; Female; Humans

1972
The diagnosis and management of paroxysmal trigeminal neuralgia in association with a temporomandibular joint dysfunction.
    Oral surgery, oral medicine, and oral pathology, 1974, Volume: 38, Issue:6

    Topics: Arthritis, Rheumatoid; Autonomic Nerve Block; Carbamazepine; Dermatitis; Female; Humans; Indomethaci

1974
[Anti-inflammatory action of Polfa methindol in experimental studies].
    Reumatologia, 1971, Volume: 9, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Dermatitis; Female; Freund's Adjuvant; Guinea Pigs; In

1971