indomethacin has been researched along with Delayed Hypersensitivity in 69 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oedema was measured after the challenging injection." | 5.26 | Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs. ( Arrigoni-Martelli, E; Bramm, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976) |
| " The anti- oedema effect was compared with indomethacin." | 3.76 | Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum. ( Antonisamy, P; Ignacimuthu, S, 2010) |
| " No statistically significant difference in delayed hypersensitivity response to dinitrochlorobenzene was found between indomethacin-treated, tumor-bearing and control groups." | 3.67 | Indomethacin and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in the hamster buccal pouch. ( Gould, AR; Grant, FT; Miller, RL; Perry, DA, 1985) |
| "Indomethacin and cyclophosphamide (CY) were used in an attempt to modify the suppressive effects of spleen cell populations from mice with disseminated histoplasmosis at 1 week of infection." | 3.66 | Pharmacological modulation of suppressor cell activity in mice with disseminated histoplasmosis. ( Bullock, WE; Deepe, GS; Kravitz, GR, 1983) |
| "Indomethacin was used as a reference drug for anti-inflammatory studies." | 1.39 | Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats. ( Pragasam, SJ; Rasool, M; Venkatesan, V, 2013) |
| " Its use as a second agent in combination with another immunosuppressant might enable reduction in the dosage or time of application." | 1.30 | A low dose immunorestorative effect of aporphinoid alkaloid oxoglaucine on experimentally immunosuppressed and infected mice. ( Ivanovska, N; Philipov, S, 1997) |
| "Experimental allergic encephalomyelitis (EAE) is an autoimmune inflammatory disease of the central nervous system (CNS)." | 1.29 | Prostaglandins and inhibitors of arachidonate metabolism suppress experimental allergic encephalomyelitis. ( Jensen, MA; Reder, AT; Sapugay, AM; Thapar, M, 1994) |
| "The ovalbumin serum level was higher in indomethacin-treated mice and the increase was proportional to the dose of indomethacin." | 1.29 | Decrease in systemic tolerance to fed ovalbumin in indomethacin-treated mice. ( Belaiche, J; Deprez, M; Franchimont, D; Lamproye, A; Louis, E; Mahieu, P; Schaaf, N, 1996) |
| " Thus, CP-331 exerted anti-inflammatory, analgesic, and antipyretic effects but without showing gastric toxicity, which is a common side effect of anti-inflammatory drugs." | 1.28 | Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate. ( Abe, T; Itokazu, Y; Ohya, O; Omata, T; Segawa, Y; Tagashira, E; Tsuzuike, N; Ueda, I; Yoshida, K, 1992) |
| "Inflammation was induced by injection of CMC as a non-specific irritant, lipopolysaccharide (LPS) as an activator of macrophages, and methylated bovine serum albumin (m-BSA) as an inducer of delayed type hypersensitivity." | 1.28 | Comparative studies on inflammatory reactions induced by non-immunological and immunological stimuli in an air pouch and in a carboxymethyl cellulose (CMC)-induced inflammatory pouch. ( Isaji, M; Naito, J, 1992) |
| " Drug studies were performed, using a 4-day dosing schedule, on optimal DTH elicited on day 10, suboptimal DTH elicited on day 15, and AA (day 16)." | 1.28 | Drug actions on delayed-type hypersensitivity in rats with developing and established adjuvant arthritis. ( Hambleton, P; McMahon, S, 1990) |
| "Indomethacin was active too when predosed in the rat EAE model." | 1.27 | Immunomodulating activity of Wy-41,770 (5H-dibenzo[A,D]cyclohepten-5-ylidene) acetic acid. ( Carlson, RP; Datko, LJ; Lewis, AJ; O'Neill-Davis, L, 1986) |
| " The compounds of most interest, 18 and 28, were further tested in a model of adjuvant-induced arthritis; in this system, both compounds were active when dosed intraperitoneally but failed to produce significant activity when dosed orally at subtoxic doses." | 1.26 | Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues. ( Millonig, RC; Rovnyak, GC; Schwartz, J; Shu, V, 1982) |
| "Therefore, diminished delayed hypersensitivity in aged humans may be related to deficient lymphokine production, which in turn appears to involve a decreased capacity of the lymphocytes producing these mediators to undergo activation by recall antigens." | 1.26 | Failure of lymphokine-producing lymphocytes from aged humans to undergo activation by recall antigens. ( Collins-Lech, C; Guansing, AR; Larson, SE; Sohnle, PG, 1980) |
| "The effects of different antirheumatic drugs administered according to various dosing regimes on tuberculin hypersensitivity in rats have been assessed quantitating the changes of exudate volume and mononuclear cells immigration at the site of challenge." | 1.26 | Delayed hypersensitivity to tuberculin in rats: effects of antirheumatic drugs. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1979) |
| "Oedema was measured after the challenging injection." | 1.26 | Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs. ( Arrigoni-Martelli, E; Bramm, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976) |
| " Dosing with D-penicillamine (25 mg/kg) and levamisole (5 mg/kg) at the time of challenge produced a significant enhancement of the reaction." | 1.26 | Pertussis vaccine pleurisy: a model of delayed hypersensitivity. ( Arrigoni-Martelli, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (65.22) | 18.7374 |
| 1990's | 18 (26.09) | 18.2507 |
| 2000's | 2 (2.90) | 29.6817 |
| 2010's | 4 (5.80) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rovnyak, GC | 1 |
| Millonig, RC | 2 |
| Schwartz, J | 1 |
| Shu, V | 1 |
| Uramaru, N | 1 |
| Shigematsu, H | 1 |
| Toda, A | 1 |
| Eyanagi, R | 1 |
| Kitamura, S | 1 |
| Ohta, S | 1 |
| Murunikkara, V | 1 |
| Rasool, M | 2 |
| Antonisamy, P | 1 |
| Ignacimuthu, S | 1 |
| Pragasam, SJ | 1 |
| Venkatesan, V | 1 |
| Guzmán, S | 1 |
| Gato, A | 1 |
| Lamela, M | 1 |
| Freire-Garabal, M | 1 |
| Calleja, JM | 1 |
| Altmann, DM | 1 |
| Blyth, WA | 1 |
| Goodwin, JS | 2 |
| Ceuppens, J | 1 |
| Scott, GM | 1 |
| Stewart, WE | 1 |
| Tyrrell, DA | 1 |
| Cantell, K | 1 |
| Cartwright, T | 1 |
| Edy, VG | 1 |
| Bartocci, A | 2 |
| Welker, RD | 1 |
| Schlick, E | 2 |
| Chirigos, MA | 2 |
| Nisula, BC | 2 |
| Deepe, GS | 1 |
| Kravitz, GR | 1 |
| Bullock, WE | 1 |
| DeShazo, RD | 2 |
| Levinson, AI | 1 |
| Dvorak, HF | 1 |
| Tomioka, H | 1 |
| Saito, H | 1 |
| Braun, DP | 1 |
| Nisius, S | 1 |
| Hollinshead, A | 1 |
| Harris, JE | 1 |
| Mason, UG | 1 |
| Kirkpatrick, CH | 1 |
| Sohnle, PG | 1 |
| Larson, SE | 1 |
| Collins-Lech, C | 1 |
| Guansing, AR | 1 |
| Morley, J | 1 |
| Beets, JL | 1 |
| Bray, MA | 1 |
| Paul, W | 1 |
| Kato, K | 1 |
| Yamamoto, K | 2 |
| Yoshida, T | 1 |
| Cohen, S | 1 |
| Lipsmeyer, EA | 1 |
| Vadas, P | 1 |
| Hay, JB | 1 |
| Yoshino, S | 1 |
| Ohuchi, K | 1 |
| Tsurufuji, S | 1 |
| Papademetriou, V | 1 |
| Favalli, C | 2 |
| Garaci, E | 2 |
| Etheredge, E | 1 |
| Santoro, MG | 2 |
| Jaffe, BM | 2 |
| Saha, B | 1 |
| Bandyopadhyay, D | 1 |
| Roy, S | 1 |
| Reder, AT | 1 |
| Thapar, M | 1 |
| Sapugay, AM | 1 |
| Jensen, MA | 1 |
| Gogos, CA | 1 |
| Maroulis, J | 1 |
| Zoumbos, NC | 1 |
| Salsa, B | 1 |
| Kalfarentzos, F | 1 |
| Gao, JX | 1 |
| Issekutz, AC | 1 |
| Markewitz, A | 2 |
| Faist, E | 3 |
| Lang, S | 2 |
| Endres, S | 1 |
| Fuchs, D | 2 |
| Reichart, B | 2 |
| de Souza, MS | 1 |
| Smith, AL | 1 |
| Beck, DS | 1 |
| Terwilliger, GA | 1 |
| Fikrig, E | 1 |
| Barthold, SW | 1 |
| Louis, E | 1 |
| Franchimont, D | 1 |
| Deprez, M | 1 |
| Lamproye, A | 1 |
| Schaaf, N | 1 |
| Mahieu, P | 1 |
| Belaiche, J | 1 |
| Di Pierro, F | 1 |
| d'Atri, G | 1 |
| Marcucci, F | 1 |
| Leoni, F | 1 |
| Kamada, H | 1 |
| Goto, M | 1 |
| Matsuura, S | 1 |
| Takaoka, Y | 1 |
| Nagai, H | 1 |
| Ivanovska, N | 1 |
| Philipov, S | 1 |
| Gregory, MS | 1 |
| Duffner, LA | 1 |
| Hahn, EL | 1 |
| Tai, HH | 1 |
| Faunce, DE | 1 |
| Kovacs, EJ | 1 |
| Bramm, E | 2 |
| Binderup, L | 1 |
| Arrigoni-Martelli, E | 3 |
| Muscoplat, CC | 1 |
| Rakich, PM | 1 |
| Thoen, CO | 1 |
| Johnson, DW | 1 |
| Karakoz, I | 1 |
| Krejcí, J | 1 |
| Vosmík, F | 1 |
| Pekárek, J | 1 |
| Blaszczyk, B | 1 |
| Gieldanowski, J | 2 |
| Hraba, T | 1 |
| Hála, K | 1 |
| Huskisson, EC | 2 |
| Willoughby, DA | 2 |
| Dieppe, PA | 2 |
| Segawa, Y | 1 |
| Ohya, O | 1 |
| Abe, T | 1 |
| Omata, T | 1 |
| Tsuzuike, N | 1 |
| Itokazu, Y | 1 |
| Yoshida, K | 1 |
| Tagashira, E | 1 |
| Ueda, I | 1 |
| Isaji, M | 1 |
| Naito, J | 1 |
| Tabara, M | 1 |
| Watanabe, M | 1 |
| Zarius, S | 1 |
| Schildberg, FW | 1 |
| Wachter, H | 1 |
| Ertel, W | 1 |
| Cohnert, T | 1 |
| Huber, P | 1 |
| Inthorn, D | 1 |
| Heberer, G | 1 |
| Shroff, KE | 2 |
| Sengupta, SR | 2 |
| Kamat, RS | 2 |
| Sainis, KB | 1 |
| Hambleton, P | 1 |
| McMahon, S | 1 |
| Raud, J | 1 |
| Dahlén, SE | 1 |
| Sydbom, A | 1 |
| Lindbom, L | 1 |
| Hedqvist, P | 1 |
| Grönneberg, R | 1 |
| Zetterström, O | 1 |
| Abraham, WM | 1 |
| Stevenson, JS | 1 |
| Garrido, R | 1 |
| Ruebush, MJ | 1 |
| Steel, LK | 1 |
| Kennedy, DA | 1 |
| Tajima, S | 1 |
| Nishimura, N | 1 |
| Ito, K | 1 |
| Tominaga, M | 1 |
| Kohno, S | 1 |
| Tanaka, K | 1 |
| Ohata, K | 1 |
| Mastino, A | 1 |
| Esteban, M | 1 |
| Carlson, RP | 1 |
| Datko, LJ | 1 |
| O'Neill-Davis, L | 1 |
| Lewis, AJ | 1 |
| Okuyama, H | 1 |
| Matsunaga, T | 1 |
| Kobayashi, S | 1 |
| Hashimoto, Y | 1 |
| Price, P | 1 |
| Holt, PG | 1 |
| Latter, DA | 1 |
| Tchervenkov, JI | 1 |
| Nohr, CW | 1 |
| Christou, NV | 1 |
| Gould, AR | 1 |
| Miller, RL | 1 |
| Grant, FT | 1 |
| Perry, DA | 1 |
| Walker, SM | 1 |
| Smolin, G | 1 |
| Keates, RH | 1 |
| Goldlust, MB | 1 |
| Maguire, WE | 1 |
| Rubin, B | 1 |
| Schulze, E | 1 |
| Wojnar, RJ | 1 |
| Turkheimer, AR | 1 |
| Schreiber, WF | 1 |
| Brittain, RJ | 1 |
| Malaguzzi Valeri, C | 1 |
| Pipitone, V | 1 |
| Pelczarska, A | 1 |
| Gillissen, G | 1 |
| Breining, H | 1 |
| Palchetti, R | 1 |
| Scarpelli, PT | 1 |
| Tortoli, V | 1 |
3 reviews available for indomethacin and Delayed Hypersensitivity
| Article | Year |
|---|---|
Regulation of the immune response by prostaglandins.
Topics: Adult; Aged; Animals; Antibody Formation; Autoantibodies; Cattle; Cell Transformation, Neoplastic; C | 1983 |
Immunologic effects of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Dinoprostone; Graft Survival; Guinea Pigs; Hu | 1984 |
Regulation of allergic responses by prostaglandins: a review.
Topics: Anaphylaxis; Anti-Inflammatory Agents; Humans; Hypersensitivity; Hypersensitivity, Delayed; Indometh | 1980 |
5 trials available for indomethacin and Delayed Hypersensitivity
| Article | Year |
|---|---|
The effect of parenteral indomethacin on T-lymphocyte subpopulations and cytokine production in patients under major surgical operations.
Topics: Adult; Aged; Cytokines; Female; Humans; Hypersensitivity, Delayed; Indomethacin; Injections, Intramu | 1995 |
Successful restoration of cell-mediated immune response after cardiopulmonary bypass by immunomodulation.
Topics: Aged; Cardiopulmonary Bypass; Drug Therapy, Combination; Female; Humans; Hypersensitivity, Delayed; | 1993 |
Immunomodulatory therapy with thymopentin and indomethacin. Successful restoration of interleukin-2 synthesis in patients undergoing major surgery.
Topics: Adjuvants, Immunologic; Aged; Antigens, CD; Biopterins; Cardiac Surgical Procedures; Cell Division; | 1991 |
Immunoprotective effects of cyclooxygenase inhibition in patients with major surgical trauma.
Topics: Aged; Aorta, Abdominal; CD4 Antigens; Cells, Cultured; Cyclooxygenase Inhibitors; Female; Gastrectom | 1990 |
Inhibition of the late phase response to anti-IgE in humans by indomethacin.
Topics: Adult; Animals; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Arachidonic Acids; Cyclooxygen | 1985 |
61 other studies available for indomethacin and Delayed Hypersensitivity
| Article | Year |
|---|---|
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Chemical Phenomena; Che | 1982 |
Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics.
Topics: Allergens; Analgesics; Animals; Antipyretics; Body Temperature; Drug Design; Fever; Guinea Pigs; Hyp | 2010 |
Trikatu, an herbal compound as immunomodulatory and anti-inflammatory agent in the treatment of rheumatoid arthritis--an experimental study.
Topics: Alkenes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; F | 2014 |
Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum.
Topics: Acetic Acid; Analgesics; Anaphylaxis; Animals; Behavior, Animal; Chromobacterium; Dose-Response Rela | 2010 |
Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Antioxidants; Antirheuma | 2013 |
Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chlorella; Ch | 2003 |
Lipopolysaccharide-induced suppressor cells for delayed-type hypersensitivity to herpes simplex virus: nature of suppressor cell and effect on pathogenesis of herpes simplex.
Topics: Animals; Antibodies, Viral; Cell Movement; Cyclophosphamide; Female; Herpes Simplex; Hypersensitivit | 1984 |
Skin reactions to interferon inoculations are reduced but not abolished by purification.
Topics: Chromatography, Gel; Erythema; Histamine; Histamine Antagonists; Humans; Hypersensitivity, Delayed; | 1980 |
Immunosuppressive activity of human chorionic gonadotrophin preparations in vivo: evidence for gonadal dependence.
Topics: Animals; Binding, Competitive; Castration; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subu | 1983 |
Pharmacological modulation of suppressor cell activity in mice with disseminated histoplasmosis.
Topics: Animals; Cells, Cultured; Cyclophosphamide; Hemolytic Plaque Technique; Histoplasmosis; Hypersensiti | 1983 |
The late phase skin reaction: paradigm or epiphenomena?
Topics: Adrenal Cortex Hormones; Animals; Arthus Reaction; Chemotaxis, Leukocyte; Dermatitis, Atopic; Diseas | 1983 |
Effect of phorbol myristate acetate, a tumor-promoting agent, on the growth of Mycobacterium lepraemurium in the mouse footpad.
Topics: Acetates; Acetic Acid; Animals; Dexamethasone; Female; Hypersensitivity, Delayed; Indomethacin; Infl | 1983 |
Serial immune testing in surgically resected lung cancer patients.
Topics: Cell Adhesion; Freund's Adjuvant; Humans; Hypersensitivity, Delayed; Immunotherapy; Indomethacin; Lu | 1983 |
Modulation of immunologic responses in nontuberculous mycobacterial infections with indomethacin.
Topics: Dermatitis, Atopic; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Indomethacin; Lymphocyte | 1984 |
Failure of lymphokine-producing lymphocytes from aged humans to undergo activation by recall antigens.
Topics: Adult; Aged; Candida; Humans; Hypersensitivity, Delayed; Indomethacin; Leukocyte Migration-Inhibitor | 1980 |
Involvement of prostaglandin E1 in delayed-type hypersensitivity suppression induced with live Mycobacterium bovis BCG.
Topics: Alprostadil; Animals; Cell Migration Inhibition; Hypersensitivity, Delayed; Indomethacin; Macrophage | 1982 |
Biological control of lymphokine function.
Topics: Animals; Cathepsins; Desensitization, Immunologic; Guinea Pigs; Hypersensitivity, Delayed; Indometha | 1982 |
Effect of cimetidine and indomethacin on delayed hypersensitivity.
Topics: Animals; Cimetidine; Drug Synergism; Drug Therapy, Combination; Guanidines; Guinea Pigs; Hypersensit | 1982 |
The appearance and significance of phospholipase A2 in lymph draining tuberculin reactions.
Topics: Animals; Blood Circulation; Capillary Permeability; Concanavalin A; Female; Hyperemia; Hypersensitiv | 1982 |
Induction of a delayed type hypersensitivity to carrageenin in mice.
Topics: Animals; Carrageenan; Dexamethasone; Hypersensitivity, Delayed; Indomethacin; Male; Mice; Mice, Inbr | 1982 |
Effect of crude and purified human chorionic gonadotropin on murine delayed-type hypersensitivity: a role for prostaglandins.
Topics: Animals; Aspirin; Chorionic Gonadotropin; Female; Hypersensitivity, Delayed; Indomethacin; Male; Mic | 1982 |
Influence of PGE on the immune response in melanoma-bearing mice.
Topics: Agglutinins; Animals; Antibody-Producing Cells; Cell Transformation, Neoplastic; Female; Hypersensit | 1980 |
Indomethacin-responsive mononuclear cell dysfunction in Hodgkins disease.
Topics: Hodgkin Disease; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Indomethacin; Lymphocyte Act | 1980 |
Immunobiological studies on experimental visceral leishmaniasis. IV. Kinetics of evolution of disease-promoting versus host-protective cells of monocyte-macrophage lineage and their characterization.
Topics: Animals; Antigen-Presenting Cells; Cell Separation; Cyclooxygenase Inhibitors; Female; Hypersensitiv | 1995 |
Prostaglandins and inhibitors of arachidonate metabolism suppress experimental allergic encephalomyelitis.
Topics: Alprostadil; Animals; Arachidonic Acid; Drug Combinations; Edema; Encephalomyelitis, Autoimmune, Exp | 1994 |
The effect of ebselen on T-lymphocyte migration to arthritic joints and dermal inflammatory reactions in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Azoles; Chemotaxis, Leuko | 1994 |
Long-term study of cell-mediated responses to Borrelia burgdorferi in the laboratory mouse.
Topics: Animals; B-Lymphocytes; Borrelia burgdorferi Group; Hypersensitivity, Delayed; Immunity, Cellular; I | 1993 |
Decrease in systemic tolerance to fed ovalbumin in indomethacin-treated mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Enteritis; Femal | 1996 |
Use of type I and type IV hypersensitivity responses to define the immunopharmacological profile of drugs.
Topics: Animals; C-Reactive Protein; Cyclosporine; Drug Evaluation, Preclinical; Female; Hypersensitivity, D | 1997 |
Immunopharmacological studies on collagen-induced arthritis in dark Agouti (DA) rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Arth | 1997 |
A low dose immunorestorative effect of aporphinoid alkaloid oxoglaucine on experimentally immunosuppressed and infected mice.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Apomorphine; Artemisinins; Cyclophosphami | 1997 |
Differential production of prostaglandin E(2) in male and female mice subjected to thermal injury contributes to the gender difference in immune function: possible role for 15-hydroxyprostaglandin dehydrogenase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cell Division; Cells, Cultured; Cyclooxygen | 2000 |
Delayed hypersensitivity to tuberculin in rats: effects of antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Cyclophosphamide; Drug Evaluation, Preclinical; Drug Hypersensiti | 1979 |
Enhancement of lymphocyte blastogenic and delayed hypersensitivity skin responses by indomethacin.
Topics: Animals; Antigens, Bacterial; Cattle; Concanavalin A; Guinea Pigs; Hypersensitivity, Delayed; Immuni | 1978 |
Effect of various anti-inflammatory drugs on tuberculin reaction in chickens.
Topics: Animals; Anti-Inflammatory Agents; Chickens; Comb and Wattles; Hypersensitivity, Delayed; Indomethac | 1977 |
Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs.
Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Edema; Female; Freund's Adjuvant; Hyp | 1976 |
Pertussis vaccine pleurisy: a model of delayed hypersensitivity.
Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Freund's Adjuvant; Hypersensitivity, | 1976 |
Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; E | 1992 |
Comparative studies on inflammatory reactions induced by non-immunological and immunological stimuli in an air pouch and in a carboxymethyl cellulose (CMC)-induced inflammatory pouch.
Topics: Air Sacs; Animals; Carboxymethylcellulose Sodium; Dexamethasone; Hypersensitivity, Delayed; Indometh | 1992 |
Abrogation of the suppressive effect of 12-O-tetradecanoylphorbol 13-acetate and 7,12-dimethylbenz[a]anthracene on footpad reaction of mice by indomethacin and some inhibitors of tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Drug Interactions; Hypersensitiv | 1992 |
Route-related variation in immunogenicity of mycobacteria.
Topics: Animals; Cross Reactions; Hypersensitivity, Delayed; Indomethacin; Injections, Intradermal; Injectio | 1990 |
Role of antigen-presenting cells in variation in immunogenicity of mycobacteria.
Topics: Animals; Antigen-Presenting Cells; Antigens, Bacterial; Histocompatibility Antigens Class II; Hypers | 1990 |
Drug actions on delayed-type hypersensitivity in rats with developing and established adjuvant arthritis.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Bacterial; Art | 1990 |
Enhancement of acute allergic inflammation by indomethacin is reversed by prostaglandin E2: apparent correlation with in vivo modulation of mediator release.
Topics: Animals; Cricetinae; Cyclooxygenase Inhibitors; Dinoprostone; Histamine; Histamine Release; Hypersen | 1988 |
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chrom | 1989 |
Prostaglandin-mediated suppression of delayed-type hypersensitivity to infected erythrocytes during Babesia microti infection in mice.
Topics: Animals; Babesiosis; Cyclophosphamide; Erythrocytes; Hypersensitivity, Delayed; Immune Tolerance; Im | 1986 |
Suppression of delayed-type hypersensitivity mediated by macrophage-like cells in mice with experimental liver injury.
Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Catechin; Chemical and Drug Induced Liver I | 1985 |
Studies on toluene diisocyanate (TDI)-induced delayed type hypersensitivity.
Topics: Animals; Capillary Permeability; Cyanates; Dexamethasone; Drug Hypersensitivity; Hypersensitivity, D | 1985 |
Antiviral activity of a synthetic analog of prostaglandin A in mice infected with influenza A virus.
Topics: Animals; Antibodies, Viral; Antibody Formation; Aspirin; Female; Hypersensitivity, Delayed; Immunity | 1988 |
Immunomodulating activity of Wy-41,770 (5H-dibenzo[A,D]cyclohepten-5-ylidene) acetic acid.
Topics: Acetates; Animals; Arthritis, Experimental; Dibenzocycloheptenes; Encephalomyelitis, Autoimmune, Exp | 1986 |
Relationship of macrophages to defective delayed-type hypersensitivity in B6/lpr mice.
Topics: Animals; Antigens, Bacterial; Cell Migration Inhibition; Female; Hypersensitivity, Delayed; Immune T | 1986 |
Immunological consequences of intestinal helminth infections: antigen presentation and immunosuppression by peritoneal cells.
Topics: Aluminum Hydroxide; Animals; Antibody Formation; Antigen-Presenting Cells; Host-Parasite Interaction | 1986 |
The effect of indomethacin on burn-induced immunosuppression.
Topics: Abscess; Animals; Burns; Hypersensitivity, Delayed; Immune Tolerance; Indomethacin; Male; Rats; Rats | 1987 |
Indomethacin and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in the hamster buccal pouch.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cheek; Cricetinae; Dinitrochlorobenzene; Drug | 1985 |
Abrogation of macrophage-mediated suppression of T-lymphocyte proliferation with hemoglobin and hemin is a function of iron content.
Topics: Animals; Heme; Hemin; Hemoglobins; Hypersensitivity, Delayed; Immune Tolerance; Indomethacin; Iron; | 1985 |
Suppression of the corneal hypersensitivity reaction.
Topics: Aminocaproates; Animals; Antigen-Antibody Reactions; Arthus Reaction; Cornea; Hypersensitivity, Dela | 1967 |
Antiinflammatory activities of 2-acetyl- and 2-(1-hydroxyethyl)-4-(3-(dimethylamino)propyl)-3,4-dihydro-3-phenyl-2H-1,4-benzothiazine.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthus Reaction; Cell Membrane; DNA; Dogs; Edema; Ence | 1973 |
[Immunosuppressive activity of indomethacin].
Topics: Animals; Antibody Formation; Arthritis; Arthritis, Rheumatoid; Haplorhini; Hypersensitivity, Delayed | 1972 |
Mediators and nonsteroid antiinflammatory drugs in immunologically specific and nonspecific inflammatory processes.
Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Bradykinin; Chlor | 1971 |
[Experiments on the mechanism of delayed hypersensitivity reactions. VII. Functional relationship between LNPF and histones].
Topics: Animals; Capillary Permeability; Cattle; Depression, Chemical; DNA; Guinea Pigs; Histones; Hypersens | 1969 |
[Action of indomethacin on delayed allergic reactions].
Topics: Animals; Freund's Adjuvant; Guinea Pigs; Hypersensitivity, Delayed; Indomethacin; Tuberculin Test | 1966 |