Page last updated: 2024-10-29

indomethacin and Delayed Hypersensitivity

indomethacin has been researched along with Delayed Hypersensitivity in 69 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Oedema was measured after the challenging injection."5.26Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs. ( Arrigoni-Martelli, E; Bramm, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976)
" The anti- oedema effect was compared with indomethacin."3.76Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum. ( Antonisamy, P; Ignacimuthu, S, 2010)
" No statistically significant difference in delayed hypersensitivity response to dinitrochlorobenzene was found between indomethacin-treated, tumor-bearing and control groups."3.67Indomethacin and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in the hamster buccal pouch. ( Gould, AR; Grant, FT; Miller, RL; Perry, DA, 1985)
"Indomethacin and cyclophosphamide (CY) were used in an attempt to modify the suppressive effects of spleen cell populations from mice with disseminated histoplasmosis at 1 week of infection."3.66Pharmacological modulation of suppressor cell activity in mice with disseminated histoplasmosis. ( Bullock, WE; Deepe, GS; Kravitz, GR, 1983)
"Indomethacin was used as a reference drug for anti-inflammatory studies."1.39Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats. ( Pragasam, SJ; Rasool, M; Venkatesan, V, 2013)
" Its use as a second agent in combination with another immunosuppressant might enable reduction in the dosage or time of application."1.30A low dose immunorestorative effect of aporphinoid alkaloid oxoglaucine on experimentally immunosuppressed and infected mice. ( Ivanovska, N; Philipov, S, 1997)
"Experimental allergic encephalomyelitis (EAE) is an autoimmune inflammatory disease of the central nervous system (CNS)."1.29Prostaglandins and inhibitors of arachidonate metabolism suppress experimental allergic encephalomyelitis. ( Jensen, MA; Reder, AT; Sapugay, AM; Thapar, M, 1994)
"The ovalbumin serum level was higher in indomethacin-treated mice and the increase was proportional to the dose of indomethacin."1.29Decrease in systemic tolerance to fed ovalbumin in indomethacin-treated mice. ( Belaiche, J; Deprez, M; Franchimont, D; Lamproye, A; Louis, E; Mahieu, P; Schaaf, N, 1996)
" Thus, CP-331 exerted anti-inflammatory, analgesic, and antipyretic effects but without showing gastric toxicity, which is a common side effect of anti-inflammatory drugs."1.28Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate. ( Abe, T; Itokazu, Y; Ohya, O; Omata, T; Segawa, Y; Tagashira, E; Tsuzuike, N; Ueda, I; Yoshida, K, 1992)
"Inflammation was induced by injection of CMC as a non-specific irritant, lipopolysaccharide (LPS) as an activator of macrophages, and methylated bovine serum albumin (m-BSA) as an inducer of delayed type hypersensitivity."1.28Comparative studies on inflammatory reactions induced by non-immunological and immunological stimuli in an air pouch and in a carboxymethyl cellulose (CMC)-induced inflammatory pouch. ( Isaji, M; Naito, J, 1992)
" Drug studies were performed, using a 4-day dosing schedule, on optimal DTH elicited on day 10, suboptimal DTH elicited on day 15, and AA (day 16)."1.28Drug actions on delayed-type hypersensitivity in rats with developing and established adjuvant arthritis. ( Hambleton, P; McMahon, S, 1990)
"Indomethacin was active too when predosed in the rat EAE model."1.27Immunomodulating activity of Wy-41,770 (5H-dibenzo[A,D]cyclohepten-5-ylidene) acetic acid. ( Carlson, RP; Datko, LJ; Lewis, AJ; O'Neill-Davis, L, 1986)
" The compounds of most interest, 18 and 28, were further tested in a model of adjuvant-induced arthritis; in this system, both compounds were active when dosed intraperitoneally but failed to produce significant activity when dosed orally at subtoxic doses."1.26Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues. ( Millonig, RC; Rovnyak, GC; Schwartz, J; Shu, V, 1982)
"Therefore, diminished delayed hypersensitivity in aged humans may be related to deficient lymphokine production, which in turn appears to involve a decreased capacity of the lymphocytes producing these mediators to undergo activation by recall antigens."1.26Failure of lymphokine-producing lymphocytes from aged humans to undergo activation by recall antigens. ( Collins-Lech, C; Guansing, AR; Larson, SE; Sohnle, PG, 1980)
"The effects of different antirheumatic drugs administered according to various dosing regimes on tuberculin hypersensitivity in rats have been assessed quantitating the changes of exudate volume and mononuclear cells immigration at the site of challenge."1.26Delayed hypersensitivity to tuberculin in rats: effects of antirheumatic drugs. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1979)
"Oedema was measured after the challenging injection."1.26Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs. ( Arrigoni-Martelli, E; Bramm, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976)
" Dosing with D-penicillamine (25 mg/kg) and levamisole (5 mg/kg) at the time of challenge produced a significant enhancement of the reaction."1.26Pertussis vaccine pleurisy: a model of delayed hypersensitivity. ( Arrigoni-Martelli, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199045 (65.22)18.7374
1990's18 (26.09)18.2507
2000's2 (2.90)29.6817
2010's4 (5.80)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rovnyak, GC1
Millonig, RC2
Schwartz, J1
Shu, V1
Uramaru, N1
Shigematsu, H1
Toda, A1
Eyanagi, R1
Kitamura, S1
Ohta, S1
Murunikkara, V1
Rasool, M2
Antonisamy, P1
Ignacimuthu, S1
Pragasam, SJ1
Venkatesan, V1
Guzmán, S1
Gato, A1
Lamela, M1
Freire-Garabal, M1
Calleja, JM1
Altmann, DM1
Blyth, WA1
Goodwin, JS2
Ceuppens, J1
Scott, GM1
Stewart, WE1
Tyrrell, DA1
Cantell, K1
Cartwright, T1
Edy, VG1
Bartocci, A2
Welker, RD1
Schlick, E2
Chirigos, MA2
Nisula, BC2
Deepe, GS1
Kravitz, GR1
Bullock, WE1
DeShazo, RD2
Levinson, AI1
Dvorak, HF1
Tomioka, H1
Saito, H1
Braun, DP1
Nisius, S1
Hollinshead, A1
Harris, JE1
Mason, UG1
Kirkpatrick, CH1
Sohnle, PG1
Larson, SE1
Collins-Lech, C1
Guansing, AR1
Morley, J1
Beets, JL1
Bray, MA1
Paul, W1
Kato, K1
Yamamoto, K2
Yoshida, T1
Cohen, S1
Lipsmeyer, EA1
Vadas, P1
Hay, JB1
Yoshino, S1
Ohuchi, K1
Tsurufuji, S1
Papademetriou, V1
Favalli, C2
Garaci, E2
Etheredge, E1
Santoro, MG2
Jaffe, BM2
Saha, B1
Bandyopadhyay, D1
Roy, S1
Reder, AT1
Thapar, M1
Sapugay, AM1
Jensen, MA1
Gogos, CA1
Maroulis, J1
Zoumbos, NC1
Salsa, B1
Kalfarentzos, F1
Gao, JX1
Issekutz, AC1
Markewitz, A2
Faist, E3
Lang, S2
Endres, S1
Fuchs, D2
Reichart, B2
de Souza, MS1
Smith, AL1
Beck, DS1
Terwilliger, GA1
Fikrig, E1
Barthold, SW1
Louis, E1
Franchimont, D1
Deprez, M1
Lamproye, A1
Schaaf, N1
Mahieu, P1
Belaiche, J1
Di Pierro, F1
d'Atri, G1
Marcucci, F1
Leoni, F1
Kamada, H1
Goto, M1
Matsuura, S1
Takaoka, Y1
Nagai, H1
Ivanovska, N1
Philipov, S1
Gregory, MS1
Duffner, LA1
Hahn, EL1
Tai, HH1
Faunce, DE1
Kovacs, EJ1
Bramm, E2
Binderup, L1
Arrigoni-Martelli, E3
Muscoplat, CC1
Rakich, PM1
Thoen, CO1
Johnson, DW1
Karakoz, I1
Krejcí, J1
Vosmík, F1
Pekárek, J1
Blaszczyk, B1
Gieldanowski, J2
Hraba, T1
Hála, K1
Huskisson, EC2
Willoughby, DA2
Dieppe, PA2
Segawa, Y1
Ohya, O1
Abe, T1
Omata, T1
Tsuzuike, N1
Itokazu, Y1
Yoshida, K1
Tagashira, E1
Ueda, I1
Isaji, M1
Naito, J1
Tabara, M1
Watanabe, M1
Zarius, S1
Schildberg, FW1
Wachter, H1
Ertel, W1
Cohnert, T1
Huber, P1
Inthorn, D1
Heberer, G1
Shroff, KE2
Sengupta, SR2
Kamat, RS2
Sainis, KB1
Hambleton, P1
McMahon, S1
Raud, J1
Dahlén, SE1
Sydbom, A1
Lindbom, L1
Hedqvist, P1
Grönneberg, R1
Zetterström, O1
Abraham, WM1
Stevenson, JS1
Garrido, R1
Ruebush, MJ1
Steel, LK1
Kennedy, DA1
Tajima, S1
Nishimura, N1
Ito, K1
Tominaga, M1
Kohno, S1
Tanaka, K1
Ohata, K1
Mastino, A1
Esteban, M1
Carlson, RP1
Datko, LJ1
O'Neill-Davis, L1
Lewis, AJ1
Okuyama, H1
Matsunaga, T1
Kobayashi, S1
Hashimoto, Y1
Price, P1
Holt, PG1
Latter, DA1
Tchervenkov, JI1
Nohr, CW1
Christou, NV1
Gould, AR1
Miller, RL1
Grant, FT1
Perry, DA1
Walker, SM1
Smolin, G1
Keates, RH1
Goldlust, MB1
Maguire, WE1
Rubin, B1
Schulze, E1
Wojnar, RJ1
Turkheimer, AR1
Schreiber, WF1
Brittain, RJ1
Malaguzzi Valeri, C1
Pipitone, V1
Pelczarska, A1
Gillissen, G1
Breining, H1
Palchetti, R1
Scarpelli, PT1
Tortoli, V1

Reviews

3 reviews available for indomethacin and Delayed Hypersensitivity

ArticleYear
Regulation of the immune response by prostaglandins.
    Journal of clinical immunology, 1983, Volume: 3, Issue:4

    Topics: Adult; Aged; Animals; Antibody Formation; Autoantibodies; Cattle; Cell Transformation, Neoplastic; C

1983
Immunologic effects of nonsteroidal anti-inflammatory drugs.
    The American journal of medicine, 1984, Oct-15, Volume: 77, Issue:4B

    Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Dinoprostone; Graft Survival; Guinea Pigs; Hu

1984
Regulation of allergic responses by prostaglandins: a review.
    Journal of the Royal Society of Medicine, 1980, Volume: 73, Issue:6

    Topics: Anaphylaxis; Anti-Inflammatory Agents; Humans; Hypersensitivity; Hypersensitivity, Delayed; Indometh

1980

Trials

5 trials available for indomethacin and Delayed Hypersensitivity

ArticleYear
The effect of parenteral indomethacin on T-lymphocyte subpopulations and cytokine production in patients under major surgical operations.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1995, Volume: 195, Issue:2

    Topics: Adult; Aged; Cytokines; Female; Humans; Hypersensitivity, Delayed; Indomethacin; Injections, Intramu

1995
Successful restoration of cell-mediated immune response after cardiopulmonary bypass by immunomodulation.
    The Journal of thoracic and cardiovascular surgery, 1993, Volume: 105, Issue:1

    Topics: Aged; Cardiopulmonary Bypass; Drug Therapy, Combination; Female; Humans; Hypersensitivity, Delayed;

1993
Immunomodulatory therapy with thymopentin and indomethacin. Successful restoration of interleukin-2 synthesis in patients undergoing major surgery.
    Annals of surgery, 1991, Volume: 214, Issue:3

    Topics: Adjuvants, Immunologic; Aged; Antigens, CD; Biopterins; Cardiac Surgical Procedures; Cell Division;

1991
Immunoprotective effects of cyclooxygenase inhibition in patients with major surgical trauma.
    The Journal of trauma, 1990, Volume: 30, Issue:1

    Topics: Aged; Aorta, Abdominal; CD4 Antigens; Cells, Cultured; Cyclooxygenase Inhibitors; Female; Gastrectom

1990
Inhibition of the late phase response to anti-IgE in humans by indomethacin.
    Allergy, 1985, Volume: 40, Issue:1

    Topics: Adult; Animals; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Arachidonic Acids; Cyclooxygen

1985

Other Studies

61 other studies available for indomethacin and Delayed Hypersensitivity

ArticleYear
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Chemical Phenomena; Che

1982
Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics.
    Journal of medicinal chemistry, 2010, Dec-23, Volume: 53, Issue:24

    Topics: Allergens; Analgesics; Animals; Antipyretics; Body Temperature; Drug Design; Fever; Guinea Pigs; Hyp

2010
Trikatu, an herbal compound as immunomodulatory and anti-inflammatory agent in the treatment of rheumatoid arthritis--an experimental study.
    Cellular immunology, 2014, Volume: 287, Issue:1

    Topics: Alkenes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; F

2014
Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:3-4

    Topics: Acetic Acid; Analgesics; Anaphylaxis; Animals; Behavior, Animal; Chromobacterium; Dose-Response Rela

2010
Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats.
    Inflammation, 2013, Volume: 36, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Antioxidants; Antirheuma

2013
Anti-inflammatory and immunomodulatory activities of polysaccharide from Chlorella stigmatophora and Phaeodactylum tricornutum.
    Phytotherapy research : PTR, 2003, Volume: 17, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chlorella; Ch

2003
Lipopolysaccharide-induced suppressor cells for delayed-type hypersensitivity to herpes simplex virus: nature of suppressor cell and effect on pathogenesis of herpes simplex.
    Immunology, 1984, Volume: 53, Issue:3

    Topics: Animals; Antibodies, Viral; Cell Movement; Cyclophosphamide; Female; Herpes Simplex; Hypersensitivit

1984
Skin reactions to interferon inoculations are reduced but not abolished by purification.
    Journal of interferon research, 1980,Fall, Volume: 1, Issue:1

    Topics: Chromatography, Gel; Erythema; Histamine; Histamine Antagonists; Humans; Hypersensitivity, Delayed;

1980
Immunosuppressive activity of human chorionic gonadotrophin preparations in vivo: evidence for gonadal dependence.
    Cellular immunology, 1983, Volume: 82, Issue:2

    Topics: Animals; Binding, Competitive; Castration; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subu

1983
Pharmacological modulation of suppressor cell activity in mice with disseminated histoplasmosis.
    Infection and immunity, 1983, Volume: 41, Issue:1

    Topics: Animals; Cells, Cultured; Cyclophosphamide; Hemolytic Plaque Technique; Histoplasmosis; Hypersensiti

1983
The late phase skin reaction: paradigm or epiphenomena?
    Annals of allergy, 1983, Volume: 51, Issue:2 Pt 1

    Topics: Adrenal Cortex Hormones; Animals; Arthus Reaction; Chemotaxis, Leukocyte; Dermatitis, Atopic; Diseas

1983
Effect of phorbol myristate acetate, a tumor-promoting agent, on the growth of Mycobacterium lepraemurium in the mouse footpad.
    Microbiology and immunology, 1983, Volume: 27, Issue:5

    Topics: Acetates; Acetic Acid; Animals; Dexamethasone; Female; Hypersensitivity, Delayed; Indomethacin; Infl

1983
Serial immune testing in surgically resected lung cancer patients.
    Cancer immunology, immunotherapy : CII, 1983, Volume: 15, Issue:2

    Topics: Cell Adhesion; Freund's Adjuvant; Humans; Hypersensitivity, Delayed; Immunotherapy; Indomethacin; Lu

1983
Modulation of immunologic responses in nontuberculous mycobacterial infections with indomethacin.
    Journal of clinical immunology, 1984, Volume: 4, Issue:2

    Topics: Dermatitis, Atopic; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Indomethacin; Lymphocyte

1984
Failure of lymphokine-producing lymphocytes from aged humans to undergo activation by recall antigens.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 124, Issue:5

    Topics: Adult; Aged; Candida; Humans; Hypersensitivity, Delayed; Indomethacin; Leukocyte Migration-Inhibitor

1980
Involvement of prostaglandin E1 in delayed-type hypersensitivity suppression induced with live Mycobacterium bovis BCG.
    Infection and immunity, 1982, Volume: 36, Issue:1

    Topics: Alprostadil; Animals; Cell Migration Inhibition; Hypersensitivity, Delayed; Indomethacin; Macrophage

1982
Biological control of lymphokine function.
    Federation proceedings, 1982, Volume: 41, Issue:8

    Topics: Animals; Cathepsins; Desensitization, Immunologic; Guinea Pigs; Hypersensitivity, Delayed; Indometha

1982
Effect of cimetidine and indomethacin on delayed hypersensitivity.
    Transplantation, 1982, Volume: 33, Issue:1

    Topics: Animals; Cimetidine; Drug Synergism; Drug Therapy, Combination; Guanidines; Guinea Pigs; Hypersensit

1982
The appearance and significance of phospholipase A2 in lymph draining tuberculin reactions.
    The American journal of pathology, 1982, Volume: 107, Issue:3

    Topics: Animals; Blood Circulation; Capillary Permeability; Concanavalin A; Female; Hyperemia; Hypersensitiv

1982
Induction of a delayed type hypersensitivity to carrageenin in mice.
    Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:4

    Topics: Animals; Carrageenan; Dexamethasone; Hypersensitivity, Delayed; Indomethacin; Male; Mice; Mice, Inbr

1982
Effect of crude and purified human chorionic gonadotropin on murine delayed-type hypersensitivity: a role for prostaglandins.
    Cellular immunology, 1982, Volume: 71, Issue:2

    Topics: Animals; Aspirin; Chorionic Gonadotropin; Female; Hypersensitivity, Delayed; Indomethacin; Male; Mic

1982
Influence of PGE on the immune response in melanoma-bearing mice.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 125, Issue:2

    Topics: Agglutinins; Animals; Antibody-Producing Cells; Cell Transformation, Neoplastic; Female; Hypersensit

1980
Indomethacin-responsive mononuclear cell dysfunction in Hodgkins disease.
    Clinical immunology and immunopathology, 1980, Volume: 17, Issue:1

    Topics: Hodgkin Disease; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Indomethacin; Lymphocyte Act

1980
Immunobiological studies on experimental visceral leishmaniasis. IV. Kinetics of evolution of disease-promoting versus host-protective cells of monocyte-macrophage lineage and their characterization.
    Scandinavian journal of immunology, 1995, Volume: 42, Issue:5

    Topics: Animals; Antigen-Presenting Cells; Cell Separation; Cyclooxygenase Inhibitors; Female; Hypersensitiv

1995
Prostaglandins and inhibitors of arachidonate metabolism suppress experimental allergic encephalomyelitis.
    Journal of neuroimmunology, 1994, Volume: 54, Issue:1-2

    Topics: Alprostadil; Animals; Arachidonic Acid; Drug Combinations; Edema; Encephalomyelitis, Autoimmune, Exp

1994
The effect of ebselen on T-lymphocyte migration to arthritic joints and dermal inflammatory reactions in the rat.
    International journal of immunopharmacology, 1994, Volume: 16, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Azoles; Chemotaxis, Leuko

1994
Long-term study of cell-mediated responses to Borrelia burgdorferi in the laboratory mouse.
    Infection and immunity, 1993, Volume: 61, Issue:5

    Topics: Animals; B-Lymphocytes; Borrelia burgdorferi Group; Hypersensitivity, Delayed; Immunity, Cellular; I

1993
Decrease in systemic tolerance to fed ovalbumin in indomethacin-treated mice.
    International archives of allergy and immunology, 1996, Volume: 109, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Enteritis; Femal

1996
Use of type I and type IV hypersensitivity responses to define the immunopharmacological profile of drugs.
    Journal of pharmacological and toxicological methods, 1997, Volume: 37, Issue:2

    Topics: Animals; C-Reactive Protein; Cyclosporine; Drug Evaluation, Preclinical; Female; Hypersensitivity, D

1997
Immunopharmacological studies on collagen-induced arthritis in dark Agouti (DA) rats.
    Japanese journal of pharmacology, 1997, Volume: 74, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Arth

1997
A low dose immunorestorative effect of aporphinoid alkaloid oxoglaucine on experimentally immunosuppressed and infected mice.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:9

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Apomorphine; Artemisinins; Cyclophosphami

1997
Differential production of prostaglandin E(2) in male and female mice subjected to thermal injury contributes to the gender difference in immune function: possible role for 15-hydroxyprostaglandin dehydrogenase.
    Cellular immunology, 2000, Nov-01, Volume: 205, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cell Division; Cells, Cultured; Cyclooxygen

2000
Delayed hypersensitivity to tuberculin in rats: effects of antirheumatic drugs.
    Acta pharmacologica et toxicologica, 1979, Volume: 44, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cyclophosphamide; Drug Evaluation, Preclinical; Drug Hypersensiti

1979
Enhancement of lymphocyte blastogenic and delayed hypersensitivity skin responses by indomethacin.
    Infection and immunity, 1978, Volume: 20, Issue:3

    Topics: Animals; Antigens, Bacterial; Cattle; Concanavalin A; Guinea Pigs; Hypersensitivity, Delayed; Immuni

1978
Effect of various anti-inflammatory drugs on tuberculin reaction in chickens.
    Folia biologica, 1977, Volume: 23, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Chickens; Comb and Wattles; Hypersensitivity, Delayed; Indomethac

1977
Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs.
    Agents and actions, 1976, Volume: 6, Issue:5

    Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Edema; Female; Freund's Adjuvant; Hyp

1976
Pertussis vaccine pleurisy: a model of delayed hypersensitivity.
    Agents and actions, 1976, Volume: 6, Issue:5

    Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Freund's Adjuvant; Hypersensitivity,

1976
Anti-inflammatory, analgesic, and antipyretic effects and gastrointestinal toxicity of the new anti-inflammatory drug N-(3-[3-(piperidinylmethyl)phenoxy]propyl)-carbamoylmethylthio ]ethyl 1-(p-chlorobenzoyl) 5-methoxy-2-methyl-3-indolylacetate.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; E

1992
Comparative studies on inflammatory reactions induced by non-immunological and immunological stimuli in an air pouch and in a carboxymethyl cellulose (CMC)-induced inflammatory pouch.
    International journal of experimental pathology, 1992, Volume: 73, Issue:2

    Topics: Air Sacs; Animals; Carboxymethylcellulose Sodium; Dexamethasone; Hypersensitivity, Delayed; Indometh

1992
Abrogation of the suppressive effect of 12-O-tetradecanoylphorbol 13-acetate and 7,12-dimethylbenz[a]anthracene on footpad reaction of mice by indomethacin and some inhibitors of tumor promotion.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Drug Interactions; Hypersensitiv

1992
Route-related variation in immunogenicity of mycobacteria.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1990, Volume: 58, Issue:1

    Topics: Animals; Cross Reactions; Hypersensitivity, Delayed; Indomethacin; Injections, Intradermal; Injectio

1990
Role of antigen-presenting cells in variation in immunogenicity of mycobacteria.
    Clinical and experimental immunology, 1990, Volume: 79, Issue:2

    Topics: Animals; Antigen-Presenting Cells; Antigens, Bacterial; Histocompatibility Antigens Class II; Hypers

1990
Drug actions on delayed-type hypersensitivity in rats with developing and established adjuvant arthritis.
    Agents and actions, 1990, Volume: 29, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Bacterial; Art

1990
Enhancement of acute allergic inflammation by indomethacin is reversed by prostaglandin E2: apparent correlation with in vivo modulation of mediator release.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:7

    Topics: Animals; Cricetinae; Cyclooxygenase Inhibitors; Dinoprostone; Histamine; Histamine Release; Hypersen

1988
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chrom

1989
Prostaglandin-mediated suppression of delayed-type hypersensitivity to infected erythrocytes during Babesia microti infection in mice.
    Cellular immunology, 1986, Apr-01, Volume: 98, Issue:2

    Topics: Animals; Babesiosis; Cyclophosphamide; Erythrocytes; Hypersensitivity, Delayed; Immune Tolerance; Im

1986
Suppression of delayed-type hypersensitivity mediated by macrophage-like cells in mice with experimental liver injury.
    Immunology, 1985, Volume: 54, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Carbon Tetrachloride; Catechin; Chemical and Drug Induced Liver I

1985
Studies on toluene diisocyanate (TDI)-induced delayed type hypersensitivity.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:2

    Topics: Animals; Capillary Permeability; Cyanates; Dexamethasone; Drug Hypersensitivity; Hypersensitivity, D

1985
Antiviral activity of a synthetic analog of prostaglandin A in mice infected with influenza A virus.
    Archives of virology, 1988, Volume: 99, Issue:1-2

    Topics: Animals; Antibodies, Viral; Antibody Formation; Aspirin; Female; Hypersensitivity, Delayed; Immunity

1988
Immunomodulating activity of Wy-41,770 (5H-dibenzo[A,D]cyclohepten-5-ylidene) acetic acid.
    Journal of immunopharmacology, 1986, Volume: 8, Issue:2

    Topics: Acetates; Animals; Arthritis, Experimental; Dibenzocycloheptenes; Encephalomyelitis, Autoimmune, Exp

1986
Relationship of macrophages to defective delayed-type hypersensitivity in B6/lpr mice.
    Clinical and experimental immunology, 1986, Volume: 66, Issue:3

    Topics: Animals; Antigens, Bacterial; Cell Migration Inhibition; Female; Hypersensitivity, Delayed; Immune T

1986
Immunological consequences of intestinal helminth infections: antigen presentation and immunosuppression by peritoneal cells.
    The Australian journal of experimental biology and medical science, 1986, Volume: 64 ( Pt 5)

    Topics: Aluminum Hydroxide; Animals; Antibody Formation; Antigen-Presenting Cells; Host-Parasite Interaction

1986
The effect of indomethacin on burn-induced immunosuppression.
    The Journal of surgical research, 1987, Volume: 43, Issue:3

    Topics: Abscess; Animals; Burns; Hypersensitivity, Delayed; Immune Tolerance; Indomethacin; Male; Rats; Rats

1987
Indomethacin and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in the hamster buccal pouch.
    Journal of oral pathology, 1985, Volume: 14, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cheek; Cricetinae; Dinitrochlorobenzene; Drug

1985
Abrogation of macrophage-mediated suppression of T-lymphocyte proliferation with hemoglobin and hemin is a function of iron content.
    Cellular immunology, 1985, Volume: 90, Issue:1

    Topics: Animals; Heme; Hemin; Hemoglobins; Hypersensitivity, Delayed; Immune Tolerance; Indomethacin; Iron;

1985
Suppression of the corneal hypersensitivity reaction.
    American journal of ophthalmology, 1967, Volume: 63, Issue:2

    Topics: Aminocaproates; Animals; Antigen-Antibody Reactions; Arthus Reaction; Cornea; Hypersensitivity, Dela

1967
Antiinflammatory activities of 2-acetyl- and 2-(1-hydroxyethyl)-4-(3-(dimethylamino)propyl)-3,4-dihydro-3-phenyl-2H-1,4-benzothiazine.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthus Reaction; Cell Membrane; DNA; Dogs; Edema; Ence

1973
[Immunosuppressive activity of indomethacin].
    La Clinica terapeutica, 1972, May-31, Volume: 61, Issue:4

    Topics: Animals; Antibody Formation; Arthritis; Arthritis, Rheumatoid; Haplorhini; Hypersensitivity, Delayed

1972
Mediators and nonsteroid antiinflammatory drugs in immunologically specific and nonspecific inflammatory processes.
    Archivum immunologiae et therapiae experimentalis, 1971, Volume: 19, Issue:1

    Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Bradykinin; Chlor

1971
[Experiments on the mechanism of delayed hypersensitivity reactions. VII. Functional relationship between LNPF and histones].
    Arztliche Forschung, 1969, Aug-10, Volume: 23, Issue:8

    Topics: Animals; Capillary Permeability; Cattle; Depression, Chemical; DNA; Guinea Pigs; Histones; Hypersens

1969
[Action of indomethacin on delayed allergic reactions].
    Rivista critica di clinica medica, 1966, Volume: 66, Issue:1

    Topics: Animals; Freund's Adjuvant; Guinea Pigs; Hypersensitivity, Delayed; Indomethacin; Tuberculin Test

1966