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indomethacin and Delayed Effects, Prenatal Exposure

indomethacin has been researched along with Delayed Effects, Prenatal Exposure in 45 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"The use of indomethacin as a tocolytic agent for preterm labor is associated with an increased risk for severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia."8.91Antenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: a systematic review with metaanalysis. ( Hammers, AL; Kaunitz, AM; Sanchez-Ramos, L, 2015)
"Long-term indomethacin treatment during pregnancy may lead to the development of renal failure and irreversible renal damage with cystic dilatation of developing nephrons in an exposed fetus."7.69Persistent anuria, neonatal death, and renal microcystic lesions after prenatal exposure to indomethacin. ( Bavoux, F; Carlus, C; Delezoide, AL; Gubler, MC; Narcy, F; van der Heijden, BJ, 1994)
"Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study."6.67Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994)
"The use of indomethacin as a tocolytic agent for preterm labor is associated with an increased risk for severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia."4.91Antenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: a systematic review with metaanalysis. ( Hammers, AL; Kaunitz, AM; Sanchez-Ramos, L, 2015)
"This review, which summarizes our findings concerning the long-term effects of pre-, peri- and postnatal factors affecting development, nociception and sensorimotor functions, focuses on three areas: 1) perinatal factors influencing nociception in adult rats were examined in rats with hippocampal lesions, after the administration of stress influencing and psychostimulant drugs (dexamethasone, indomethacine and methamphetamine); 2) the effect of pre- and early postnatal methamphetamine administration was shown to impair the development of sensorimotor functions tested in rat pups throughout the preweaning period; 3) the effect of extensive dorsal rhizotomy of the brachial plexus during the early postnatal period was studied with respect to neuropathic pain development and sensorimotor functions."4.84Prenatal and perinatal factors influencing nociception, addiction and behavior during ontogenetic development. ( Franek, M; Hrubá, L; Pometlová, M; Rokyta, R; Schutová, B; Slamberová, R; Vaculín, S; Yamamotová, A, 2008)
" Up to the present day, several cases of severe and sometimes irreversible renal insufficiency have been described in neonates exposed to indomethacin prenatally or in the first days of life for treatment of patent ductus arteriosus (PDA)."4.81NSAID-induced nephrotoxicity from the fetus to the child. ( Cuzzolin, L; Dal Cerè, M; Fanos, V, 2001)
"To examine whether antenatal steroids (ANS), alone or with early indomethacin, are associated with spontaneous intestinal perforation (SIP)."3.73New insights into spontaneous intestinal perforation using a national data set (3): antenatal steroids have no adverse association with spontaneous intestinal perforation. ( Attridge, JT; Clark, R; Gordon, PV, 2006)
"Preterm infants with exposure to antenatal indomethacin might be at increased risk of grade I and II intraventricular haemorrhage and those with both ante- and postnatal exposure at an increased risk of necrotising enterocolitis and sepsis."3.70Perinatal indomethacin treatment and neonatal complications in preterm infants. ( Ikonen, S; Ojala, R; Tammela, O, 2000)
"Long-term indomethacin treatment during pregnancy may lead to the development of renal failure and irreversible renal damage with cystic dilatation of developing nephrons in an exposed fetus."3.69Persistent anuria, neonatal death, and renal microcystic lesions after prenatal exposure to indomethacin. ( Bavoux, F; Carlus, C; Delezoide, AL; Gubler, MC; Narcy, F; van der Heijden, BJ, 1994)
"2 to 31 wk) exposed to indomethacin during the last 2 days of pregnancy (group I)."3.67Renal functional impairment in preterm neonates related to intrauterine indomethacin exposure. ( Grose, W; Nauta, J; Oranje, WA; Provoost, AP; Sauer, PJ; vd Heijden, AJ; Wolff, ED, 1988)
"Women in acute preterm labor with cervical dilatation 1-6 cm were randomized to receive one of three first-line tocolytic drugs."2.77Effect of antenatal tocolysis on neonatal outcomes. ( Briery, CM; Keiser, SD; Klauser, CK; Kosek, MA; Martin, RW; Morrison, JC, 2012)
"Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study."2.67Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994)
"NSAIDs are generally considered to be safe and well tolerated, but, even with the advent of selective COX-2 inhibitors, nephrotoxicity remains a concern."2.47Acute nephrotoxicity of NSAID from the foetus to the adult. ( Antonucci, R; Evangelista, M; Fanos, V; Finco, G; Musu, M; Polati, E; Ribuffo, D; Sanna, D; Schweiger, V, 2011)
" Immunophenotyping analysis using flow cytometry (FCM) indicated that the proportion and number of CD45RA(+) cells increased, and the proportion of CD3(-) NKR-P1A(+) cells decreased in males when dosed with IND at 1."1.34Effect of prenatal administration of NSAIDs on the immune response in juvenile and adult rats. ( Fujiwara, M; Furusawa, S; Kushima, K; Oda, K; Sakuma, S, 2007)
"Chorioamnionitis was positively correlated with the risk, but did not reach statistical significance."1.33Possible antenatal and perinatal related factors in development of cystic periventricular leukomalacia. ( Itakura, A; Matsuzawa, K; Mizutani, S; Murata, Y; Okumura, A; Wakai, K, 2005)
"Indomethacin treatment at 3 mg/kg/day from day 18 to day 20 of gestation significantly decreased the activity of 15-PGDH in neonatal lungs."1.29Inhibitory effect of indomethacin on neonatal lung catabolism of prostaglandin E2: possible mechanism of the re-opening of the ductus arteriosus after indomethacin therapy. ( Akahori, F; Arishima, K; Ikeda, Y; Masaoka, T; Takizawa, T; Togashi, H; Yamamoto, M, 1996)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.11)18.7374
1990's17 (37.78)18.2507
2000's14 (31.11)29.6817
2010's9 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dean, A1
Mungall, W1
McKinnell, C1
Sharpe, RM1
Zielinsky, P1
Busato, S1
Hammers, AL2
Sanchez-Ramos, L2
Kaunitz, AM2
Hallman, M2
Pesonen, E2
Teramo, K2
Musu, M1
Finco, G1
Antonucci, R1
Polati, E1
Sanna, D1
Evangelista, M1
Ribuffo, D1
Schweiger, V1
Fanos, V2
Barreto, RR1
Franco, Ede S1
Brasileiro, CF1
de Oliveira, AP1
Dimech, GS1
Malta, DJ1
Cazuzu, JS1
Leite, AC1
da Silva, TG1
Maia, MB1
Roghair, RD1
Volk, KA1
Lamb, FS1
Segar, JL1
Klauser, CK1
Briery, CM1
Keiser, SD1
Martin, RW1
Kosek, MA1
Morrison, JC1
Hwang, H1
Murphy, JJ1
Gow, KW1
Magee, JF1
Bekhit, E1
Jamieson, D1
Levenson, D1
Amateau, SK1
McCarthy, MM1
Murata, Y1
Itakura, A1
Matsuzawa, K1
Okumura, A1
Wakai, K1
Mizutani, S1
Doyle, NM1
Gardner, MO1
Wells, L1
Qualls, C1
Papile, LA1
Attridge, JT1
Clark, R1
Gordon, PV1
Kushima, K1
Oda, K1
Sakuma, S1
Furusawa, S1
Fujiwara, M1
Amin, SB1
Kamaluddeen, M1
Sangem, M1
Rokyta, R1
Yamamotová, A1
Slamberová, R1
Franek, M1
Vaculín, S1
Hrubá, L1
Schutová, B1
Pometlová, M1
Cunnane, SC1
Herget, J1
Hampl, V1
Povýsilová, V1
Slavík, Z1
van den Anker, JN1
Hop, WC1
de Groot, R1
van der Heijden, BJ2
Broerse, HM1
Lindemans, J1
Sauer, PJ3
Carlus, C1
Narcy, F1
Bavoux, F1
Delezoide, AL1
Gubler, MC1
Eronen, M2
Kurki, T1
Ylikorkala, O1
Major, CA1
Lewis, DF1
Harding, JA1
Porto, MA1
Garite, TJ1
Buderus, S1
Thomas, B1
Fahnenstich, H1
Kowalewski, S1
Ment, LR1
Oh, W1
Ehrenkranz, RA1
Allan, WC1
Alexandrov, VA1
Bespalov, VG1
Petrov, AS1
Troyan, DN1
al-Alaiyan, S1
Seshia, MM1
Casiro, OG1
Salokorpi, T1
von Wendt, L1
Takizawa, T1
Ikeda, Y1
Togashi, H1
Yamamoto, M1
Arishima, K1
Akahori, F1
Masaoka, T1
Norton, ME1
Morozova, EV2
Holemans, K1
Gerber, RT1
Meurrens, K1
De Clerck, F1
Poston, L1
Van Assche, FA1
Vermillion, ST1
Newman, RB1
Ojala, R1
Ikonen, S1
Tammela, O1
Benesová, O1
Tejkalová, H1
Kristofiková, Z1
Panajotova, V1
Husek, P1
Cuzzolin, L1
Dal Cerè, M1
Weintraub, Z1
Solovechick, M1
Reichman, B1
Rotschild, A1
Waisman, D1
Davkin, O1
Lusky, A1
Bental, Y1
Petrenko, VM1
Petrenko, EV1
Goldbarg, SH1
Takahashi, Y1
Cruz, C1
Kajino, H1
Roman, C1
Liu, BM1
Chen, YQ1
Mauray, F1
Clyman, RI1
Shamir, R1
Litwin, A1
Merlob, A1
Guignard, JP1
Gouyon, JB1
vd Heijden, AJ1
Provoost, AP2
Nauta, J2
Grose, W1
Oranje, WA1
Wolff, ED2
van der Heijden, AJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Vaginal Indomethacin Versus Oral Nifedipine for Preterm Labor; a Randomized Controlled Trial[NCT04404686]Phase 2/Phase 3300 participants (Anticipated)Interventional2020-10-31Not yet recruiting
Generic Database: A Survey of Morbidity and Mortality in Very Low Birth Weight Infants[NCT00063063]80,000 participants (Anticipated)Observational1987-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for indomethacin and Delayed Effects, Prenatal Exposure

ArticleYear
Prenatal effects of maternal consumption of polyphenol-rich foods in late pregnancy upon fetal ductus arteriosus.
    Birth defects research. Part C, Embryo today : reviews, 2013, Volume: 99, Issue:4

    Topics: Constriction; Diet; Ductus Arteriosus; Female; Fetus; Humans; Indomethacin; Maternal Exposure; Polyp

2013
Antenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: a systematic review with metaanalysis.
    American journal of obstetrics and gynecology, 2015, Volume: 212, Issue:4

    Topics: Cerebral Ventricles; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infa

2015
Acute nephrotoxicity of NSAID from the foetus to the adult.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:12

    Topics: Acute Kidney Injury; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Child; Female; Hum

2011
Prenatal and perinatal factors influencing nociception, addiction and behavior during ontogenetic development.
    Physiological research, 2008, Volume: 57 Suppl 3

    Topics: Animals; Animals, Newborn; Behavior, Addictive; Behavior, Animal; Dexamethasone; Female; Humans; Ind

2008
Teratogen update: fetal effects of indomethacin administration during pregnancy.
    Teratology, 1997, Volume: 56, Issue:4

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Embryonic and Fetal Development; Female; Ge

1997
NSAID-induced nephrotoxicity from the fetus to the child.
    Drug safety, 2001, Volume: 24, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Ductus Arteriosus, Patent; Female;

2001
[Indomethacin and a tocolytic agent: fetal and neonatal outcome].
    Harefuah, 1990, Dec-02, Volume: 119, Issue:11

    Topics: Female; Humans; Indomethacin; Infant, Newborn; Male; Obstetric Labor, Premature; Pregnancy; Prenatal

1990
Adverse effects of drugs on the immature kidney.
    Biology of the neonate, 1988, Volume: 53, Issue:4

    Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Female; Fetus; Furosemide; Glome

1988

Trials

5 trials available for indomethacin and Delayed Effects, Prenatal Exposure

ArticleYear
Effect of antenatal tocolysis on neonatal outcomes.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:12

    Topics: Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Magnesium

2012
Effects of prenatal exposure to betamethasone and indomethacin on the glomerular filtration rate in the preterm infant.
    Pediatric research, 1994, Volume: 36, Issue:5

    Topics: Betamethasone; Birth Weight; Female; Gestational Age; Glomerular Filtration Rate; Humans; Indomethac

1994
Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor.
    The Journal of pediatrics, 1994, Volume: 124, Issue:5 Pt 1

    Topics: Adult; Bronchopulmonary Dysplasia; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature;

1994
Antenatal exposure to steroids and the additional prophylaxis effect of indomethacin to prevent intraventricular hemorrhage.
    Pediatrics, 1996, Volume: 97, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Embryonic and Fetal Development; Femal

1996
Growth and development until 18 months of children exposed to tocolytics indomethacin or nylidrin.
    Neuropediatrics, 1996, Volume: 27, Issue:4

    Topics: Child Development; Female; Follow-Up Studies; Growth; Humans; Indomethacin; Infant, Newborn; Infant,

1996

Other Studies

32 other studies available for indomethacin and Delayed Effects, Prenatal Exposure

ArticleYear
Prostaglandins, masculinization and its disorders: effects of fetal exposure of the rat to the cyclooxygenase inhibitor- indomethacin.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Cryptorchidism; Cyclooxygenase Inhibitors; Dinoprostone; Female; Fetal Development; Humans;

2013
Reply: To PMID 25448524.
    American journal of obstetrics and gynecology, 2015, Volume: 213, Issue:6

    Topics: Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Intracranial Hemorrhages; Leukomalacia, Pe

2015
Indomethacin as a tocolytic harmful to preterm infant.
    American journal of obstetrics and gynecology, 2015, Volume: 213, Issue:6

    Topics: Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Intracranial Hemorrhages; Leukomalacia, Pe

2015
Early undernutrition is associated with attenuated inflammatory response and alteration in pharmacological efficacy of indomethacin in rats.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, May-12, Volume: 46, Issue:1-2

    Topics: Analysis of Variance; Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; C

2012
Impact of maternal dexamethasone on coronary PGE(2) production and prostaglandin-dependent coronary reactivity.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2012, Sep-01, Volume: 303, Issue:5

    Topics: Angiotensin II; Animals; Cells, Cultured; Coronary Vessels; Cyclooxygenase Inhibitors; Dexamethasone

2012
Are localized intestinal perforations distinct from necrotizing enterocolitis?
    Journal of pediatric surgery, 2003, Volume: 38, Issue:5

    Topics: Adult; Catheterization; Dexamethasone; Diagnosis, Differential; Enterocolitis, Necrotizing; Female;

2003
The youngest children are too frequently subject to drug errors, study says.
    Report on medical guidelines & outcomes research, 2002, Nov-29, Volume: 13, Issue:23

    Topics: Anti-Infective Agents; Antibodies, Monoclonal; Antiviral Agents; Child, Preschool; Cisapride; Female

2002
Induction of PGE2 by estradiol mediates developmental masculinization of sex behavior.
    Nature neuroscience, 2004, Volume: 7, Issue:6

    Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Dinoprostone; Estradiol; Female; Indomethacin;

2004
Possible antenatal and perinatal related factors in development of cystic periventricular leukomalacia.
    Brain & development, 2005, Volume: 27, Issue:1

    Topics: Apgar Score; Case-Control Studies; Causality; Cerebral Palsy; Chorioamnionitis; Comorbidity; Female;

2005
Outcome of very low birth weight infants exposed to antenatal indomethacin for tocolysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2005, Volume: 25, Issue:5

    Topics: Cause of Death; Cohort Studies; Critical Care; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing

2005
New insights into spontaneous intestinal perforation using a national data set (3): antenatal steroids have no adverse association with spontaneous intestinal perforation.
    Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:11

    Topics: Case-Control Studies; Drug Administration Schedule; Female; Humans; Incidence; Indomethacin; Infant;

2006
Effect of prenatal administration of NSAIDs on the immune response in juvenile and adult rats.
    Toxicology, 2007, Apr-11, Volume: 232, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Diclofenac; Enzyme-Li

2007
Neurodevelopmental outcome of premature infants after exposure to antenatal indomethacin.
    American journal of obstetrics and gynecology, 2008, Volume: 199, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Child Development; Cohort St

2008
Maternal essential fatty acid supplementation increases zinc absorption in neonatal rats: relevance to the defect in zinc absorption in acrodermatitis enteropathica.
    Pediatric research, 1982, Volume: 16, Issue:8

    Topics: Acrodermatitis; Animals; Arachidonic Acids; Fatty Acids, Essential; Female; Gastrointestinal Disease

1982
Long-term effects of prenatal indomethacin administration on the pulmonary circulation in rats.
    The European respiratory journal, 1995, Volume: 8, Issue:2

    Topics: Animals; Female; Hypertension, Pulmonary; Hypoxia; Indomethacin; Lung; Male; Pregnancy; Prenatal Exp

1995
Persistent anuria, neonatal death, and renal microcystic lesions after prenatal exposure to indomethacin.
    American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:3

    Topics: Adult; Anuria; Dilatation, Pathologic; Female; Fetal Death; Humans; Immunohistochemistry; Indomethac

1994
Tocolysis with indomethacin increases the incidence of necrotizing enterocolitis in the low-birth-weight neonate.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Birth Weight; Chi-Square Distribution; Cohort Studies; Enterocolitis, Pseudomembranous; Female; Gest

1994
Renal failure in two preterm infants: toxic effect of prenatal maternal indomethacin treatment?
    British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:1

    Topics: Acute Kidney Injury; Adult; Amniocentesis; Cesarean Section; Female; Humans; Indomethacin; Infant, N

1993
Study of post-natal effect of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. III. Inhibitory action of indomethacin, voltaren, theophylline and epsilon-aminocaproic acid.
    Carcinogenesis, 1996, Volume: 17, Issue:9

    Topics: Aminocaproic Acid; Animals; Anticarcinogenic Agents; Brain Neoplasms; Carcinogens; Central Nervous S

1996
Neurodevelopmental outcome of infants exposed to indomethacin antenatally.
    Journal of perinatal medicine, 1996, Volume: 24, Issue:4

    Topics: Adult; Apgar Score; Birth Weight; Child Development; Contraindications; Female; Follow-Up Studies; G

1996
Inhibitory effect of indomethacin on neonatal lung catabolism of prostaglandin E2: possible mechanism of the re-opening of the ductus arteriosus after indomethacin therapy.
    The Journal of toxicological sciences, 1996, Volume: 21, Issue:4

    Topics: Animals; Dinoprostone; Ductus Arteriosus, Patent; Female; Hydroxyprostaglandin Dehydrogenases; Indom

1996
[Structure of the rat lymphoid organs after prenatal exposure to indomethacin during antigenic stimulation].
    Morfologiia (Saint Petersburg, Russia), 1998, Volume: 113, Issue:2

    Topics: Animals; Antibody Formation; Drug Evaluation, Preclinical; Female; Immunization; Indomethacin; Lymph

1998
Streptozotocin diabetes in the pregnant rat induces cardiovascular dysfunction in adult offspring.
    Diabetologia, 1999, Volume: 42, Issue:1

    Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Cardiovascular Diseases; Diabetes Mellitus, Expe

1999
Recent indomethacin tocolysis is not associated with neonatal complications in preterm infants.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:5 Pt 1

    Topics: Birth Weight; Case-Control Studies; Delivery, Obstetric; Drug Administration Schedule; Female; Gesta

1999
Perinatal indomethacin treatment and neonatal complications in preterm infants.
    European journal of pediatrics, 2000, Volume: 159, Issue:3

    Topics: Cerebral Hemorrhage; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infa

2000
Neuro-immuno-teratogenicity of drugs used in neonatal pharmacotherapy in relation to the ontogenic stage at the time of their administration.
    General physiology and biophysics, 1999, Volume: 18 Spec No

    Topics: Aging; Animals; Animals, Newborn; Antibody Formation; Brain; Dexamethasone; Female; Humans; Immunity

1999
Effect of maternal tocolysis on the incidence of severe periventricular/intraventricular haemorrhage in very low birthweight infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2001, Volume: 85, Issue:1

    Topics: Anti-Inflammatory Agents; Apgar Score; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; I

2001
[Compensatory responses in lymph nodes following by prenatal indomethacin exposure].
    Morfologiia (Saint Petersburg, Russia), 2001, Volume: 119, Issue:1

    Topics: Adaptation, Physiological; Animals; Female; Indomethacin; Luminescent Measurements; Lymph Nodes; Pre

2001
In utero indomethacin alters O2 delivery to the fetal ductus arteriosus: implications for postnatal patency.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Death; Ductus Arteriosus; Ductus Arteriosus,

2002
[Structure of the mesenteric lymph nodes in fetuses and offspring of white rats under the effect of indomethacin on the mother-fetus system].
    Arkhiv anatomii, gistologii i embriologii, 1989, Volume: 96, Issue:3

    Topics: Animals; Blood Cell Count; Female; Fetus; Indomethacin; Lymph Nodes; Lymphocytes; Maternal-Fetal Exc

1989
Renal functional impairment in preterm neonates related to intrauterine indomethacin exposure.
    Pediatric research, 1988, Volume: 24, Issue:5

    Topics: Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Kidney; Pregnancy; Prenatal Exposu

1988
Indomethacin as an inhibitor of preterm labor. Effect on postnatal renal function.
    Contributions to nephrology, 1988, Volume: 67

    Topics: Female; Gestational Age; Glomerular Filtration Rate; Humans; Indomethacin; Infant, Newborn; Kidney;

1988