indomethacin has been researched along with Dehydration in 11 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Dehydration: The condition that results from excessive loss of water from a living organism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Under conditions of dehydration the known depletion of hypothalamic and neurohypophysial oxytocin storage was not affected by indomethacin." | 3.67 | The effects of prostaglandin synthetase inhibitor indomethacin on the hypothalamic and neurohypophysial oxytocin content in euhydrated and dehydrated male white rats. ( Bojanowska, E; Guzek, JW; Stempniak, B, 1986) |
| " In vivo prostaglandin inhibition with indomethacin or meclofenamate significantly increased urinary osmolality after 12 h of dehydration and exogenous vasopressin (1." | 3.67 | Prostaglandins and the urinary concentrating defect in potassium-depleted rabbits. ( Lifschitz, MD; McKinney, TD; Raymond, KH, 1987) |
| "Pretreatment with indomethacin (200 microg/5 microl; icv), an inhibitor of cyclo-oxygenase, significantly attenuated the ANG II-induced increase in oxytocin secretion only." | 1.31 | Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats. ( Bui, V; Kadekaro, M; Summy-Long, JY; Terrell, ML, 2001) |
| "In captopril-treated male rats, angiotensin II (AII) was continuously infused by osmotic minipumps at a rate of 5 micrograms/h." | 1.27 | Papillary plasma flow in rats. II. Hormonal control. ( Bankir, L; Bayle, F; Eloy, L; Grünfeld, JP; Ramos-Frendo, B; Trinh-Trang-Tan, MM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Machida, K | 1 |
| Wakamatsu, S | 1 |
| Izumi, Y | 1 |
| Yosifovska, T | 1 |
| Matsuzaki, T | 1 |
| Nakayama, Y | 1 |
| Kohda, Y | 1 |
| Inoue, T | 1 |
| Saito, H | 1 |
| Tomita, K | 1 |
| Nonoguchi, H | 1 |
| Eloy, L | 1 |
| Grünfeld, JP | 1 |
| Bayle, F | 1 |
| Bankir, L | 1 |
| Ramos-Frendo, B | 1 |
| Trinh-Trang-Tan, MM | 1 |
| Neumann, SZ | 1 |
| Walker, RM | 1 |
| Brown, RS | 1 |
| Stoff, JS | 1 |
| Gerber, JG | 1 |
| Nies, AS | 1 |
| Kadekaro, M | 2 |
| Terrell, ML | 2 |
| Liu, H | 1 |
| Bui, V | 2 |
| Summy-Long, JY | 2 |
| Jaffe, BM | 1 |
| Kopen, DF | 1 |
| DeSchryver-Kecskemeti, K | 1 |
| Gingerich, RL | 1 |
| Greider, M | 1 |
| Brown, J | 1 |
| Forsling, ML | 1 |
| Valdes, G | 1 |
| Slater, JD | 1 |
| Dollery, CT | 1 |
| Guzek, JW | 1 |
| Bojanowska, E | 1 |
| Stempniak, B | 1 |
| Raymond, KH | 1 |
| Lifschitz, MD | 1 |
| McKinney, TD | 1 |
11 other studies available for indomethacin and Dehydration
| Article | Year |
|---|---|
Downregulation of the V2 vasopressin receptor in dehydration: mechanisms and role of renal prostaglandin synthesis.
Topics: Animals; Aquaporin 2; Arginine Vasopressin; Dehydration; Dinoprostone; Indomethacin; Kidney; Kidney | 2007 |
Papillary plasma flow in rats. II. Hormonal control.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Castration; Dehydration; Estradiol; Female; Gona | 1983 |
Childhood diarrhoea and its treatment with indomethacin in Libya.
Topics: Animals; Child; Child, Preschool; Dehydration; Diarrhea; Diarrhea, Infantile; Fluid Therapy; Glycine | 1980 |
Role of renal prostaglandins during antidiuresis and water diuresis in man.
Topics: Adult; Arginine Vasopressin; Deamino Arginine Vasopressin; Dehydration; Diabetes Insipidus; Dinopros | 1982 |
Furosemide-induced vasodilation: importance of the state of hydration and filtration.
Topics: Animals; Blood Flow Velocity; Dehydration; Desoxycorticosterone; Dilatation, Pathologic; Dogs; Femal | 1980 |
Indomethacin prevents the L-NAME-induced increase in plasma levels of oxytocin in dehydrated rats.
Topics: Angiotensin II; Animals; Dehydration; Hypothalamo-Hypophyseal System; Indomethacin; Injections, Intr | 2000 |
Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Brain Chemistry; Central Nervous System; Cyclooxyg | 2001 |
Indomethacin-responsive pancreatic cholera.
Topics: Adenoma, Islet Cell; Aged; Dehydration; Diarrhea; Female; Gastrins; Humans; Hypercalcemia; Hypokalem | 1977 |
Antagonism of V2-receptor effect of antidiuretic hormone by atrial natriuretic peptide in man.
Topics: Arginine Vasopressin; Atrial Natriuretic Factor; Blood; Dehydration; Diuresis; Humans; Indomethacin; | 1988 |
The effects of prostaglandin synthetase inhibitor indomethacin on the hypothalamic and neurohypophysial oxytocin content in euhydrated and dehydrated male white rats.
Topics: Animals; Cyclooxygenase Inhibitors; Dehydration; Hypothalamus; Indomethacin; Male; Oxytocin; Pituita | 1986 |
Prostaglandins and the urinary concentrating defect in potassium-depleted rabbits.
Topics: Adenylate Cyclase Toxin; Animals; Dehydration; Female; Indomethacin; Kidney Concentrating Ability; K | 1987 |