indomethacin has been researched along with Death, Sudden in 7 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "TAI-284 protected rabbits from sudden death caused by intravenous injection of arachidonic acid, but the activity was about one twentieth less than that of indomethacin." | 1.26 | [Anti-inflammatory property of 6-chloro-5-cyclohexyl-1-indancarboxylic acid (TAI-284) (author's transl)]. ( Fujimura, H; Kyuki, K; Nozaki, M; Tsurumi, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobs, JS | 1 |
| Fujimura, H | 1 |
| Tsurumi, K | 1 |
| Nozaki, M | 1 |
| Kyuki, K | 1 |
| Johnson, RB | 1 |
| Ono, N | 1 |
| Yamasaki, Y | 1 |
| Yamamoto, N | 1 |
| Sunami, A | 1 |
| Miyake, H | 1 |
| Sakai, K | 1 |
| Yamazaki, T | 1 |
| Nakamura, Y | 1 |
| Sugimoto, T | 1 |
| Balduck, N | 1 |
| Otten, J | 1 |
| Verbruggen, L | 1 |
| Bougatef, A | 1 |
| Ramet, J | 1 |
| Piepsz, A | 1 |
| Smith, EF | 1 |
| Olson, RW | 1 |
7 other studies available for indomethacin and Death, Sudden
| Article | Year |
|---|---|
Sudden death in arthritic children receiving large doses of indomethacin.
Topics: Adrenal Glands; Arthritis, Juvenile; Child; Death, Sudden; Female; Humans; Indomethacin; Kidney; Lym | 1967 |
[Anti-inflammatory property of 6-chloro-5-cyclohexyl-1-indancarboxylic acid (TAI-284) (author's transl)].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Capillary Permeability; Death, Sud | 1977 |
Use of NSAIDs in long-distance runners: a risk factor for sudden death?
Topics: Adult; Death, Sudden; Humans; Indomethacin; Male; Potassium; Risk Factors; Running | 1989 |
Pharmacological studies on proglumetacin maleate, a new non-steroidal anti-inflammatory drug (4). Mode of action on anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Blood Platele | 1986 |
Protective effects of the antianginal agent nicorandil on arachidonate-induced sudden death in rats: comparison with several antianginal agents and cyclooxygenase inhibitors.
Topics: Angina Pectoris; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; D | 1985 |
Sudden death of a child with juvenile chronic arthritis, probably due to indomethacin.
Topics: Adolescent; Arthritis; Chemical and Drug Induced Liver Injury; Death, Sudden; Humans; Indomethacin; | 1987 |
Synergism between a phosphodiesterase inhibitor and modulators of thromboxane formation on thrombin-induced sudden death in rabbits.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Death, Sudden; Drug Synergism; Fat | 1987 |