indomethacin has been researched along with Cytomegalovirus in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Murine cytomegalovirus infection in spleen cultures resulted in the production of a soluble factor, VISF (virus-induced suppressive factor), which inhibited concanavalin A mitogenesis in fresh spleen cells." | 3.67 | Characterization of a murine cytomegalovirus-induced immunosuppressive factor. ( Hudson, JB; Subramaniam, R; Whyte, PF, 1987) |
| "Indomethacin and tetracaine, inhibitors of prostaglandin synthesis, inhibited production of infectious human cytomegalovirus (HCMV) in a human thyroid papillary carcinoma cell line (TPC-1) by 99." | 3.67 | Inhibitors of prostaglandin synthesis inhibit growth of human cytomegalovirus and reactivation of latent virus in a productively and latently infected human cell line. ( Hatano, M; Iida, H; Ogura, T; Sato, H; Tanaka, J, 1988) |
| "Human cytomegalovirus has previously been shown to induce the accumulation of cyclooxygenase-2 RNA, protein, and enzyme activity." | 1.35 | Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus. ( Schröer, J; Shenk, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schröer, J | 1 |
| Shenk, T | 1 |
| Nokta, MA | 1 |
| Hassan, MI | 1 |
| Loesch, K | 1 |
| Pollard, RB | 1 |
| Speir, E | 1 |
| Yu, ZX | 1 |
| Ferrans, VJ | 1 |
| Huang, ES | 1 |
| Epstein, SE | 1 |
| Whyte, PF | 1 |
| Subramaniam, R | 1 |
| Hudson, JB | 1 |
| Tanaka, J | 1 |
| Ogura, T | 1 |
| Iida, H | 1 |
| Sato, H | 1 |
| Hatano, M | 1 |
5 other studies available for indomethacin and Cytomegalovirus
| Article | Year |
|---|---|
Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cells, Cultured; Cyclooxygenase 2; Cycloo | 2008 |
Human cytomegalovirus-induced immunosuppression. Relationship to tumor necrosis factor-dependent release of arachidonic acid and prostaglandin E2 in human monocytes.
Topics: Antibodies, Monoclonal; Arachidonic Acid; Cells, Cultured; Cyclic AMP; Cycloheximide; Cytomegaloviru | 1996 |
Aspirin attenuates cytomegalovirus infectivity and gene expression mediated by cyclooxygenase-2 in coronary artery smooth muscle cells.
Topics: Antiviral Agents; Aspirin; Cells, Cultured; Coronary Vessels; Cyclooxygenase 1; Cyclooxygenase 2; Cy | 1998 |
Characterization of a murine cytomegalovirus-induced immunosuppressive factor.
Topics: Animals; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Concanavalin A; | 1987 |
Inhibitors of prostaglandin synthesis inhibit growth of human cytomegalovirus and reactivation of latent virus in a productively and latently infected human cell line.
Topics: Antigens, Viral; Cytomegalovirus; DNA-Directed DNA Polymerase; Humans; Immediate-Early Proteins; Ind | 1988 |