Page last updated: 2024-10-29

indomethacin and Cytomegalovirus Infections

indomethacin has been researched along with Cytomegalovirus Infections in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Cytomegalovirus Infections: Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults.

Research Excerpts

ExcerptRelevanceReference
"Murine cytomegalovirus infection in spleen cultures resulted in the production of a soluble factor, VISF (virus-induced suppressive factor), which inhibited concanavalin A mitogenesis in fresh spleen cells."3.67Characterization of a murine cytomegalovirus-induced immunosuppressive factor. ( Hudson, JB; Subramaniam, R; Whyte, PF, 1987)
"Human cytomegalovirus has previously been shown to induce the accumulation of cyclooxygenase-2 RNA, protein, and enzyme activity."1.35Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus. ( Schröer, J; Shenk, T, 2008)
"Sera from homosexual contacts of AIDS patients and from adults with acute cytomegalovirus infection generally lacked this suppressive activity."1.27Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes. ( Djeu, JY; Gelmann, EP; Masur, H; Quinnan, GV; Siegel, JP; Stocks, NI, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zimmermann, C1
Stuepp, RT1
Rath, IBDS1
Grando, LJ1
Daniel, FI1
Meurer, MI1
Schröer, J1
Shenk, T1
Suzumori, N1
Hattori, Y1
Kaneko, S1
Suzuki, Y1
Sugiura-Ogasawara, M1
Whyte, PF1
Subramaniam, R1
Hudson, JB1
Siegel, JP1
Djeu, JY1
Stocks, NI1
Masur, H1
Gelmann, EP1
Quinnan, GV1

Other Studies

5 other studies available for indomethacin and Cytomegalovirus Infections

ArticleYear
Diagnostic Challenge and Clinical Management of Juvenile Mandibular Chronic Osteomyelitis.
    Head and neck pathology, 2020, Volume: 14, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Cytomegalovirus Infections; D

2020
Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Dec-09, Volume: 105, Issue:49

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cells, Cultured; Cyclooxygenase 2; Cycloo

2008
Cytomegalovirus-associated acute hydramnios treated by amniocentesis and maternal indomethacin.
    Congenital anomalies, 2009, Volume: 49, Issue:4

    Topics: Amniocentesis; Amniotic Fluid; Cytomegalovirus Infections; Female; Humans; Indomethacin; Infant, New

2009
Characterization of a murine cytomegalovirus-induced immunosuppressive factor.
    Archives of virology, 1987, Volume: 96, Issue:3-4

    Topics: Animals; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Concanavalin A;

1987
Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Cells, Cultured; Cytomegalovirus Infections; Humans; Immune Tole

1985