Page last updated: 2024-10-29

indomethacin and Cystitis

indomethacin has been researched along with Cystitis in 7 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.

Research Excerpts

ExcerptRelevanceReference
"Hemorrhagic cystitis (HC) is a limiting side effect of chemotherapy with ifosfamide (IFS)."7.74Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. ( Almeida, PR; Baltazar, F; Brito, GA; Ferreira, FV; Macedo, FY; Ribeiro, RA; Schmitt, FC; Távora, F, 2008)
" Groups (N = 6-8) were submitted to right or left paw edema (PE) with carrageenan (100 microg) or Dextran (200 microg), hemorrhagic cystitis with ifosfamide (200 mg/kg, ip) or gastric injury (GI) with indomethacin (20 mg/kg, vo)."3.75Hind limb ischemic preconditioning induces an anti-inflammatory response by remote organs in rats. ( Gomes, AS; Loiola, RT; Ribeiro, RA; Rocha, EL; Simão, AF; Souza Filho, MV; Souza, MH, 2009)
"Hemorrhagic cystitis (HC) is a limiting side effect of chemotherapy with ifosfamide (IFS)."3.74Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. ( Almeida, PR; Baltazar, F; Brito, GA; Ferreira, FV; Macedo, FY; Ribeiro, RA; Schmitt, FC; Távora, F, 2008)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vladimirova, IA1
Philyppov, IB1
Kulieva, EM1
Paduraru, ON1
Shuba, YY1
Shuba, YM1
Han, JH1
Lee, MY1
Myung, SC1
Souza Filho, MV1
Loiola, RT1
Rocha, EL1
Simão, AF1
Gomes, AS1
Souza, MH1
Ribeiro, RA2
Nakahara, T1
Kubota, Y1
Saito, M1
Sakamoto, K1
Ishii, K1
Takagi-Matsumoto, H1
Ng, B1
Tsukimi, Y1
Tajimi, M1
Macedo, FY1
Baltazar, F1
Almeida, PR1
Távora, F1
Ferreira, FV1
Schmitt, FC1
Brito, GA1
Belichard, P1
Luccarini, JM1
Defrêne, E1
Faye, P1
Franck, RM1
Duclos, H1
Paquet, JL1
Pruneau, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Remote Ischemic Preconditioning on Restenosis Post Lower Limb Revascularization Angioplasty: A Pilot Randomized Control Trial[NCT02406131]40 participants (Anticipated)Interventional2018-04-30Suspended (stopped due to logistic issues - no available scans for participants at the moment need to postponed starting dates)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for indomethacin and Cystitis

ArticleYear
[Impact of diabetic complications on neuromuscular transmission in the smooth muscle of the bladder of rats with experimental diabetes].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2015, Volume: 61, Issue:4

    Topics: Animals; Atropine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Diabetes Mellitus

2015
The effect of endothelin-1 on the production of interleukin-6 in cultured human detrusor smooth muscle cells, and the effect of interleukin-6 on the contractile response of bladder smooth muscle strips from rats.
    BJU international, 2009, Volume: 104, Issue:5

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cyclooxygenase Inhibitors; Cystit

2009
Hind limb ischemic preconditioning induces an anti-inflammatory response by remote organs in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2009, Volume: 42, Issue:10

    Topics: Acute Disease; Animals; Carrageenan; Cystitis; Edema; Hindlimb; Ifosfamide; Indomethacin; Inflammati

2009
Protease-activated receptor-2-mediated contraction of urinary bladder is enhanced in cyclophosphamide-treated rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:2

    Topics: Animals; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Dinoprostone; In Vitro Techniques; Indomethac

2004
Effects of NSAIDs on bladder function in normal and cystitis rats: a comparison study of aspirin, indomethacin, and ketoprofen.
    Journal of pharmacological sciences, 2004, Volume: 95, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclophosphamide; Cystitis; Female; Gastr

2004
Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:1

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystitis; Drug Therapy, Combination; Etorico

2008
Pharmacological and molecular evidence for kinin B1 receptor expression in urinary bladder of cyclophosphamide-treated rats.
    British journal of pharmacology, 1999, Volume: 128, Issue:1

    Topics: Acrolein; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Cyclophos

1999