indomethacin has been researched along with Cystinosis in 4 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Cystinosis: A metabolic disease characterized by the defective transport of CYSTINE across the lysosomal membrane due to mutation of a membrane protein cystinosin. This results in cystine accumulation and crystallization in the cells causing widespread tissue damage. In the KIDNEY, nephropathic cystinosis is a common cause of RENAL FANCONI SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three children with nephropathic cystinosis were treated with indomethacin 3 mg/kg a day for periods ranging from 9 to 18 months." | 7.66 | Effect of indomethacin on clinical progress and renal function in cystinosis. ( Al-Dahhan, J; Chantler, C; Haycock, GB; Mak, RH, 1982) |
| "Only indomethacin treatment was successful in reversing the biochemical abnormalities and improving the growth pattern." | 6.65 | Successful indomethacin treatment of two paediatric patients with severe tubulopathies. A boy with an unusual hypercalciuria and a girl with cystinosis. ( Bétend, B; David, L; François, R; Hermier, M; Vincent, M, 1979) |
| "Three children with nephropathic cystinosis were treated with indomethacin 3 mg/kg a day for periods ranging from 9 to 18 months." | 3.66 | Effect of indomethacin on clinical progress and renal function in cystinosis. ( Al-Dahhan, J; Chantler, C; Haycock, GB; Mak, RH, 1982) |
| "Only indomethacin treatment was successful in reversing the biochemical abnormalities and improving the growth pattern." | 2.65 | Successful indomethacin treatment of two paediatric patients with severe tubulopathies. A boy with an unusual hypercalciuria and a girl with cystinosis. ( Bétend, B; David, L; François, R; Hermier, M; Vincent, M, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lemire, J | 1 |
| Kaplan, BS | 1 |
| Haycock, GB | 1 |
| Al-Dahhan, J | 1 |
| Mak, RH | 1 |
| Chantler, C | 1 |
| Bétend, B | 1 |
| David, L | 1 |
| Vincent, M | 1 |
| Hermier, M | 1 |
| François, R | 1 |
| Pintos-Morell, G | 1 |
| Jean, G | 1 |
| Dechaux, M | 1 |
| Niaudet, P | 1 |
1 trial available for indomethacin and Cystinosis
| Article | Year |
|---|---|
Successful indomethacin treatment of two paediatric patients with severe tubulopathies. A boy with an unusual hypercalciuria and a girl with cystinosis.
Topics: Aldosterone; Body Water; Calcium; Child, Preschool; Clinical Trials as Topic; Cystinosis; Fanconi Sy | 1979 |
3 other studies available for indomethacin and Cystinosis
| Article | Year |
|---|---|
The various renal manifestations of the nephropathic form of cystinosis.
Topics: Aldosterone; Bartter Syndrome; Child, Preschool; Cystinosis; Desoxycorticosterone; Diabetes Insipidu | 1984 |
Effect of indomethacin on clinical progress and renal function in cystinosis.
Topics: Body Water; Child; Child, Preschool; Cystinosis; Female; Glomerular Filtration Rate; Humans; Indomet | 1982 |
Increased monocyte-dependent suppression of polyclonal activation of B lymphocytes from cystinotic children.
Topics: Adolescent; B-Lymphocytes; Cells, Cultured; Child; Child, Preschool; Cystinosis; Dinoprostone; Human | 1991 |