Page last updated: 2024-10-29

indomethacin and Cyanosis

indomethacin has been researched along with Cyanosis in 3 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.

Research Excerpts

ExcerptRelevanceReference
"Two twins born to a mother who had been treated with Indomethacin at the end of pregnancy presented with variable but transitory hypoxemia."7.66[Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)]. ( Boulley, AM; Dehan, M; Gabilan, JC; Hernandorena, X; Laudignon, N; Lhermitte, C; Ropert, JC; Vial, M, 1980)
"Two twins born to a mother who had been treated with Indomethacin at the end of pregnancy presented with variable but transitory hypoxemia."3.66[Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)]. ( Boulley, AM; Dehan, M; Gabilan, JC; Hernandorena, X; Laudignon, N; Lhermitte, C; Ropert, JC; Vial, M, 1980)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Distefano, G1
Boulley, AM1
Dehan, M1
Vial, M1
Hernandorena, X1
Ropert, JC1
Laudignon, N1
Lhermitte, C1
Gabilan, JC1
Sharpe, GL1
Thalme, B1
Larsson, KS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253]Phase 344 participants (Anticipated)Interventional2016-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for indomethacin and Cyanosis

ArticleYear
[The pharmacological manipulation of Botallo's duct in the duct-dependent congenital cardiopathies and in the preterm infants with respiratory distress. A review and personal findings].
    Minerva pediatrica, 2005, Volume: 57, Issue:1

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Angiography; C

2005

Other Studies

2 other studies available for indomethacin and Cyanosis

ArticleYear
[Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)].
    Archives francaises de pediatrie, 1980, Volume: 37, Issue:5

    Topics: Adult; Cyanosis; Diseases in Twins; Female; Humans; Indomethacin; Infant, Newborn; Infant, Newborn,

1980
Studies on closure of the ductus arteriosus. XI. Ductal closure in utero by a prostaglandin synthetase inhibitor.
    Prostaglandins, 1974, Dec-10, Volume: 8, Issue:5

    Topics: Animals; Blood; Carbon Dioxide; Cyanosis; Ductus Arteriosus; Female; Fetus; Hydrogen-Ion Concentrati

1974