Page last updated: 2024-10-29

indomethacin and Curling Ulcer

indomethacin has been researched along with Curling Ulcer in 91 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Curling Ulcer: Acute stress DUODENAL ULCER, usually observed in patients with extensive third-degree burns.

Research Excerpts

ExcerptRelevanceReference
"Healing with bFGF (and cimetidine) was associated with reduced NSAID induced ulcer relapse in this model of gastric ulceration."9.08Healing with basic fibroblast growth factor is associated with reduced indomethacin induced relapse in a human model of gastric ulceration. ( Brough, JL; Filipowicz, B; Hawkey, CJ; Hull, MA; Knifton, A; Vautier, G, 1997)
" This study investigated the anti-ulcerogenic and antioxidant activities of aqueous extract of Carica papaya seed against indomethacin-induced peptic ulcer in male rats."7.81Anti-ulcerogenic activity of aqueous extract of Carica papaya seed on indomethacin-induced peptic ulcer in male albino rats. ( Adaja, MC; Ajiboye, TO; Oloyede, HO; Salawu, MO, 2015)
"To evaluate, for the first time, the efficacy of copper-indomethacin in the inhibition of aberrant crypt foci formation using the azoxymethane-induced adenocarcinoma model, to examine cell viability in the HCT-116 colorectal cancer cell line, gastrointestinal permeability, mitochondrial oxidative damage, and renal toxicity in rat models."7.76Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats. ( Bonin, AM; Davies, NM; Dillon, CT; Fukuda, C; Hambley, TW; Lay, PA; Teng, XW; Yáñez, JA, 2010)
"To study the effects of growth factors on experimental duodenal ulcer healing in indomethacin-treated rats."7.72Effect of exogenous administration of transforming growth factor-beta and famotidine on the healing of duodenal ulcer under the impact of indomethacin. ( Arceiz, E; Lanas, A; Ortego, J; Pérez-Aisa, A; Sainz, R; Sopeña, F, 2003)
"Duodenal ulcer was induced in male Wistar rats with acetic acid."7.71[Effect of exogenous administration of platelet-derived growth factor and epidermal growth factor on duodenal ulcer healing in rats treated with indomethacin]. ( Arceiz Gonzalo, E; Lanas Arbeloa, A; Ortego Díez De Retana, J; Pérez Aisa, A; Sainz Samitier, R; Sopeña Biarge, F, 2002)
" Experimental gastric lesions were induced by water-immersion restraint stress, indomethacin and 80% ethanol in rats; whereas duodenal ulcers were produced by treatment of rats with cysteamine."7.69Effect of quinacrine, a phospholipase A2 inhibitor on stress and chemically induced gastroduodenal ulcers. ( Al Moutaery, AR; Tariq, M, 1997)
"The present experiments examined the protective effect of the nitrofuran drugs, furazolidone (FZ) and nitrofurazone (NF), on duodenal ulceration induced by cysteamine or indometacin in rats."7.68Effect of nitrofurans on duodenal ulceration induced by cysteamine or indometacin. ( Ali, BH, 1991)
"We standardized a new method for producing duodenal ulcers in rats by administering indomethacin plus histamine, and investigated the pathogenesis."7.67A new model of duodenal ulcers induced in rats by indomethacin plus histamine. ( Furukawa, O; Okabe, S; Takeuchi, K; Tanaka, H, 1986)
"The purpose of these studies was to determine the role played by endogenous prostaglandins in the development of gastric ulcers produced by indomethacin, and of duodenal ulcers produced by mepirizole in rats."7.67Prostaglandin deficiency by itself is not the cause of mepirizole-induced duodenal ulcers in rats. ( Jacobson, ED; Joffe, SN; Robert, A; Tabata, K, 1987)
" Acutely induced gastric ulcers or erosions such as Shay ulcers, water-immersion stress-, indomethacin-, aspirin-, or prednisolone-induced erosions were all markedly inhibited by oral or intraduodenal administration of 10-100 mg/kg of omeprazole."7.67Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats. ( Okabe, S; Okada, Y; Yamamoto, O, 1984)
"Healing of duodenal ulcers induced by indomethacin + histamine was investigated in rats."7.67Healing process of duodenal ulcers induced by indomethacin plus histamine in rats. ( Niida, H; Okabe, S; Okada, M; Takeuchi, K, 1989)
"The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied."7.65Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977)
"Healing with bFGF (and cimetidine) was associated with reduced NSAID induced ulcer relapse in this model of gastric ulceration."5.08Healing with basic fibroblast growth factor is associated with reduced indomethacin induced relapse in a human model of gastric ulceration. ( Brough, JL; Filipowicz, B; Hawkey, CJ; Hull, MA; Knifton, A; Vautier, G, 1997)
" One hundred patients, free from endoscopically detectable lesions of the gastroduodenal mucosa, affected either by rheumatoid arthritis or osteoarthritis, and candidates for NSAID therapy, were randomly allocated either to 200 mg sulglycotide three times daily (n = 50) or to an indistinguishable placebo (n = 50) for 4 weeks, together with standard NSAID administration (50 mg diclofenac three times daily (n = 50); 50 mg indomethacin three times daily (n = 50))."5.07Sulglycotide in the prevention of nonsteroidal anti-inflammatory drug-induced gastroduodenal mucosal injury. A controlled double-blind, double-dummy, randomized endoscopic study versus placebo in rheumatic patients. ( Ardizzone, S; Bianchi Porro, G; Caruso, I; Montrone, F; Petrillo, M, 1993)
" This study investigated the anti-ulcerogenic and antioxidant activities of aqueous extract of Carica papaya seed against indomethacin-induced peptic ulcer in male rats."3.81Anti-ulcerogenic activity of aqueous extract of Carica papaya seed on indomethacin-induced peptic ulcer in male albino rats. ( Adaja, MC; Ajiboye, TO; Oloyede, HO; Salawu, MO, 2015)
"To evaluate, for the first time, the efficacy of copper-indomethacin in the inhibition of aberrant crypt foci formation using the azoxymethane-induced adenocarcinoma model, to examine cell viability in the HCT-116 colorectal cancer cell line, gastrointestinal permeability, mitochondrial oxidative damage, and renal toxicity in rat models."3.76Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats. ( Bonin, AM; Davies, NM; Dillon, CT; Fukuda, C; Hambley, TW; Lay, PA; Teng, XW; Yáñez, JA, 2010)
"The role of dietary fibre (DF), intestinal motility and leukotrienes (LTs) in the formation of small intestinal ulcers induced by indomethacin (IND) was investigated in cats."3.75Role of dietary fibres, intestinal hypermotility and leukotrienes in the pathogenesis of NSAID-induced small intestinal ulcers in cats. ( Hatao, K; Nishimura, S; Otsuka, N; Satoh, H; Shiotani, S, 2009)
"To study the effects of growth factors on experimental duodenal ulcer healing in indomethacin-treated rats."3.72Effect of exogenous administration of transforming growth factor-beta and famotidine on the healing of duodenal ulcer under the impact of indomethacin. ( Arceiz, E; Lanas, A; Ortego, J; Pérez-Aisa, A; Sainz, R; Sopeña, F, 2003)
" The acute gastric ulcer models used were pylorus ligation, indomethacin-induced and ethanol-induced gastric ulcers."3.71Effect of centrally administered prolactin on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001)
" The acute gastric ulcer models used were pylorus ligation, indomethacin, ethanol and histamine induced acute gastric ulcers."3.71Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs. ( Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S, 2001)
"Duodenal ulcer was induced in male Wistar rats with acetic acid."3.71[Effect of exogenous administration of platelet-derived growth factor and epidermal growth factor on duodenal ulcer healing in rats treated with indomethacin]. ( Arceiz Gonzalo, E; Lanas Arbeloa, A; Ortego Díez De Retana, J; Pérez Aisa, A; Sainz Samitier, R; Sopeña Biarge, F, 2002)
"Since the sexual dimorphism of gastroduodenal ulcers is well known and might possibly relate to the actions of sex hormones, we studied the role of the female sex steroids, progesterone and 17beta-estradiol in cysteamine-induced mucosal ulcers in female Wistar rats (200-220 g)."3.70Dual effect of female sex steroids on drug-induced gastroduodenal ulcers in the rat. ( Drago, F; Làszlò, F; Montoneri, C; Varga, C, 1999)
" To evaluate whether immunosuppressants have a preventive effect against indomethacin-induced gastrointestinal damage, we investigated the effects of prednisolone, cyclosporin, and the newly developed immunosuppressant FK-506 in intracolonically indomethacin-treated rats: 24 mg/kg of indomethacin, administered intracolonically for two days, caused gastric ulcers and two types of small intestinal ulcers (longitudinal ulcers and scattered small ulcers)."3.69Preventive effect of immunosuppressive agents against indomethacin-induced small intestinal ulcers in rats. ( Fujishima, M; Hizawa, K; Iida, M; Kuroki, F; Matsumoto, T; Nakamura, S, 1994)
" Experimental gastric lesions were induced by water-immersion restraint stress, indomethacin and 80% ethanol in rats; whereas duodenal ulcers were produced by treatment of rats with cysteamine."3.69Effect of quinacrine, a phospholipase A2 inhibitor on stress and chemically induced gastroduodenal ulcers. ( Al Moutaery, AR; Tariq, M, 1997)
") inhibited mepirizole-induced duodenal ulcers."3.69YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats. ( Akuzawa, S; Ito, H; Kamato, T; Kobayashi, A; Miyata, K; Nagakura, Y; Nishida, A; Takinami, Y; Yamano, M; Yuki, H, 1994)
" The compound had no activity against cysteamine-induced duodenal ulcers and lost its cytoprotective activity in adrenalectomised rats."3.68BAY P 1455, a thiazolylaminobenzimidazole derivative with gastroprotective properties in the rat. ( Bruno, M; Grassi, A; Ippen, J; Thomas, G, 1991)
"The present experiments examined the protective effect of the nitrofuran drugs, furazolidone (FZ) and nitrofurazone (NF), on duodenal ulceration induced by cysteamine or indometacin in rats."3.68Effect of nitrofurans on duodenal ulceration induced by cysteamine or indometacin. ( Ali, BH, 1991)
"This study shows that human fundic mucosa generates various PGs, particularly PGE2, and thromboxanes and this generation appears to be significantly lower in gastric ulcer than in duodenal ulcer patients or normal subjects."3.67Prostaglandins in peptic ulcer disease: effect of nonsteroidal anti-inflammatory compounds (NOSAC). ( Konturek, SJ; Kopp, B; Kwiecień, N; Obtułowicz, W; Oleksy, J; Sito, E, 1984)
" Acutely induced gastric ulcers or erosions such as Shay ulcers, water-immersion stress-, indomethacin-, aspirin-, or prednisolone-induced erosions were all markedly inhibited by oral or intraduodenal administration of 10-100 mg/kg of omeprazole."3.67Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats. ( Okabe, S; Okada, Y; Yamamoto, O, 1984)
"Healing of duodenal ulcers induced by indomethacin + histamine was investigated in rats."3.67Healing process of duodenal ulcers induced by indomethacin plus histamine in rats. ( Niida, H; Okabe, S; Okada, M; Takeuchi, K, 1989)
"The purpose of these studies was to determine the role played by endogenous prostaglandins in the development of gastric ulcers produced by indomethacin, and of duodenal ulcers produced by mepirizole in rats."3.67Prostaglandin deficiency by itself is not the cause of mepirizole-induced duodenal ulcers in rats. ( Jacobson, ED; Joffe, SN; Robert, A; Tabata, K, 1987)
"We standardized a new method for producing duodenal ulcers in rats by administering indomethacin plus histamine, and investigated the pathogenesis."3.67A new model of duodenal ulcers induced in rats by indomethacin plus histamine. ( Furukawa, O; Okabe, S; Takeuchi, K; Tanaka, H, 1986)
" Oral or intraduodenal administration of AG 629 in a dose range of 25-100 mg/kg inhibited water-immersion stress ulcer, exertion ulcer, Shay ulcer, indometacin- and acetylsalicylic acid (ASA)-induced gastric ulcer, and indomethacin-induced small intestinal ulcer in rats, histamine-induced gastric ulcer in guinea pigs, and ASA-induced gastric ulcer in dogs, though it was not effective against cysteamine-induced duodenal ulcer in rats."3.67Effects of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one, a new anti-ulcer agent, on experimental acute and chronic ulcers. ( Hirata, T; Inada, I; Inatomi, N; Maki, Y; Satoh, H; Sino, A, 1985)
" However, SM powder had no effect on water-immersion stress- or aspirin-induced gastric lesions and mepirizole-induced duodenal ulcers."3.66[Effects of SM powder, a combined herbal preparation for stomach diseases, on gastric secretion and acute gastro-duodenal lesions in rats]. ( Ikenishi, H; Ohmi, F; Okabe, S; Takaoka, A; Takeuchi, K, 1983)
"The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied."3.65Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977)
"Indomethacin (400 mg/day) was administrated orally for 10 days to eight female pigs weighing 36."1.36Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs. ( Bures, J; Kopácová, M; Kunes, M; Kvetina, J; Osterreicher, J; Pejchal, J; Rejchrt, S; Spelda, S; Tachecí, I, 2010)
"Chronic gastric ulcers were induced using acetic acid and duodenal ulcers by mercaptamine hydrochloride."1.31Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats. ( Abraham, BK; Asad, M; Balasinor, N; Koumaravelou, K; Ramaswamy, S; Shewade, DG, 2001)
"Aspirin (500 mg/kg) was given by gavage and repeated 2."1.31Protective effect of the nitric oxide donor molsidomine on indomethacin and aspirin-induced gastric injury in rats. ( Khuri, M; Mourad, FH; Nassar, CF; Shouaib, F, 2000)
"Ketotifen is an anti-allergic agent that was recently shown to prevent experimental gastric and colonic mucosal injury."1.29Ketotifen is protective against indomethacin-induced intestinal ulceration in the rat. ( Dinari, G; Karmeli, F; Marcus, H; Weizen, T; Zahavi, I, 1996)
"Portal hypertension was produced in male Sprague-Dawley rats by two-staged ligation of the portal vein."1.28The effect of portal hypertension on indomethacin-induced small intestinal ulceration in the rat. ( Chung, K; Erickson, RA; Jonas, GM, 1991)
"Cimetidine, which was used as a standard antiulcer drug for comparison, also produced a similar protective effect in most of the models used by us."1.27Gastric and duodenal antiulcer and cytoprotective effects of proglumide in rats. ( Ageel, AM; Parmar, NS; Tariq, M, 1987)
"Indomethacin pretreatment did not significantly augment the duodenal lesions induced by mepirizole or cysteamine, but did augment the gastric lesions induced by these compounds."1.27Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin. ( Kuwahara, Y; Okabe, S; Tanaka, H, 1986)
" Duodenal mucosal injury, with or without gastric lesions, related to long-term use of anti-inflammatory drugs such as aspirin, indomethacin, ibuprofen, diclofenac or others are reported in three patients, in which the diagnosis was confirmed by emergency endoscopy after hematemesis."1.26Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs. ( Ikeda, S; Tanaka, M; Uchiyama, M, 1977)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199045 (49.45)18.7374
1990's23 (25.27)18.2507
2000's17 (18.68)29.6817
2010's5 (5.49)24.3611
2020's1 (1.10)2.80

Authors

AuthorsStudies
Song, H1
Qiu, J1
Yu, C1
Xiong, M1
Ou, C1
Ren, B1
Zhong, M1
Zeng, M1
Peng, Q1
Akinbo, F1
Eze, G1
Nagai, K1
Ueno, Y1
Tanaka, S1
Hayashi, R1
Shinagawa, K1
Chayama, K1
Oloyede, HO1
Adaja, MC1
Ajiboye, TO1
Salawu, MO1
Satoh, H2
Shiotani, S1
Otsuka, N1
Hatao, K1
Nishimura, S1
Tachecí, I1
Kvetina, J1
Bures, J1
Osterreicher, J1
Kunes, M1
Pejchal, J1
Rejchrt, S1
Spelda, S1
Kopácová, M1
Bonin, AM1
Yáñez, JA1
Fukuda, C1
Teng, XW1
Dillon, CT1
Hambley, TW1
Lay, PA1
Davies, NM1
Araki, H1
Komoike, Y1
Matsumoto, M1
Tanaka, A3
Takeuchi, K10
Shostak, NA1
Riabkova, AA1
Savel'ev, VS1
Maliarova, LP1
Pérez-Aisa, A1
Sopeña, F1
Arceiz, E1
Ortego, J1
Sainz, R1
Lanas, A1
Freitas, CS1
Baggio, CH1
Da Silva-Santos, JE1
Rieck, L1
de Moraes Santos, CA1
Júnior, CC1
Ming, LC1
Garcia Cortez, DA1
Marques, MC1
Tanaka, J1
Iida, H1
Abe, M1
Yuda, Y1
Inoue, S1
Okabe, S9
Suba, V1
Murugesan, T1
Pal, M1
Mandal, SC1
Saha, BP1
Bighetti, AE1
Antônio, MA1
Kohn, LK1
Rehder, VL1
Foglio, MA1
Possenti, A1
Vilela, L1
Carvalho, JE1
Hatazawa, R1
Tanigami, M1
Ohno, R1
Yokota, A1
Miura, N1
Fukutake, M1
Yamamoto, M1
Ohtake, N1
Iizuka, S1
Imamura, S1
Tsuchiya, N1
Ishimatsu, M1
Nakamura, Y1
Ishige, A1
Watanabe, K1
Kase, Y1
Takeda, S1
Chiu, PJ1
Barnett, A1
Gerhart, C1
Policelli, M1
Kaminski, J1
Konturek, SJ1
Kwiecień, N1
Obtułowicz, W1
Oleksy, J1
Sito, E1
Kopp, B1
Bruseghini, L1
Basi, N1
Gras, J1
Llenas, J1
de Miguel, G1
Rodés, B1
Sanfeliu, C1
Vilageliu, J1
Zapatero, J1
Giraldez, A1
Yamamoto, O2
Okada, Y1
Ikenishi, H1
Ohmi, F1
Takaoka, A1
Bunton, RW1
Barrett, DC1
Palmer, DG1
Thompson, MR2
Langman, MJ1
Henry, D1
Donnelly, P1
Morris, AF1
Hughes, AO1
Matsumoto, T2
Iida, M2
Nakamura, S2
Hizawa, K2
Kuroki, F2
Fujishima, M2
Nishida, A1
Takinami, Y1
Yuki, H1
Kobayashi, A1
Akuzawa, S1
Kamato, T1
Ito, H1
Yamano, M1
Nagakura, Y1
Miyata, K1
Yamaguchi, T1
Aihara, K1
Yamada, S1
Narita, S1
Kogi, K1
Bianchi Porro, G1
Montrone, F1
Petrillo, M1
Caruso, I1
Ardizzone, S1
Terashima, K1
Shimamura, H1
Kawase, A1
Tanaka, Y1
Tanimura, T1
Kamisaki, T1
Ishizuka, Y1
Sato, M1
Zahavi, I2
Weizen, T1
Marcus, H2
Karmeli, F1
Dinari, G2
Hull, MA1
Knifton, A1
Filipowicz, B1
Brough, JL1
Vautier, G1
Hawkey, CJ1
Al Moutaery, AR1
Tariq, M2
Hirata, T2
Ukawa, H1
Kitamura, M1
Drago, F1
Montoneri, C1
Varga, C1
Làszlò, F1
Mourad, FH1
Khuri, M1
Shouaib, F1
Nassar, CF1
Kato, S1
Kunikata, T1
Umeda, M1
Han, DS1
Li, F1
Holt, L1
Connolly, K1
Hubert, M1
Miceli, R1
Okoye, Z1
Santiago, G1
Windle, K1
Wong, E1
Sartor, RB1
Asad, M3
Shewade, DG3
Koumaravelou, K3
Abraham, BK3
Vasu, S2
Ramaswamy, S3
Balasinor, N1
Pérez Aisa, A1
Sopeña Biarge, F1
Arceiz Gonzalo, E1
Sainz Samitier, R1
Ortego Díez De Retana, J1
Lanas Arbeloa, A1
Urushidani, T1
Takagi, K1
Danon, A1
Assouline, G1
Tolot, F1
Prost, G1
Guignot, B1
Pelletier, M1
Paroli, E1
Nencini, P1
Anania, MC1
Mariani, L1
Bonanomi, L1
Leonhardt, L1
Tanaka, M1
Uchiyama, M1
Ikeda, S1
Barbacci, P1
Evangelista, S1
Swift, GL1
Arnold, J1
Williams, GT1
Williams, BD1
Rhodes, J1
Khan, F1
Bukhave, K1
Akimoto, Y1
Yamasaki, S1
Kuwahara, K1
Grassi, A1
Ippen, J1
Bruno, M1
Thomas, G1
Jonas, GM1
Erickson, RA1
Chung, K1
Muramatsu, M1
Isobe, Y1
Arai, I1
Hirose-Kijima, H1
Usuki-Ito, C1
Nagai, H1
Aihara, H1
Otomo, S1
Ali, BH1
Wallace, JL1
Keenan, CM1
Mugridge, KG1
Parente, L1
DiJoseph, JF1
Borella, LE1
Wells, CL1
Mir, GN1
Isenberg, JI1
Hogan, DL1
Muñoz-Arrebola, P2
Madrid, JA2
Salido, GM2
Martinez de Victoria, E2
Kyoi, T1
Ide, Y1
Ueda, F1
Kimura, K1
Okada, M2
Niida, H1
Frank, WO1
Wallin, BA1
Berkowitz, JM1
Kimmey, MB1
Palmer, RH1
Rockhold, F1
Young, MD1
Somerville, K1
Faulkner, G1
Langman, M1
Robert, A2
Lancaster, C1
Kolbasa, KP1
Olafsson, AS1
Lum, JT1
McCarty, DJ1
Simon, B1
Dammann, HG1
Müller, P1
Furukawa, O2
Harel, L1
Waisman, Y1
Ligumsky, M1
Rosenbach, Y1
Langridge, CJ1
Holzer, P1
Sametz, W1
Parmar, NS1
Ageel, AM1
Tabata, K1
Joffe, SN1
Jacobson, ED1
Forssell, H1
Olbe, L1
Tanaka, H2
Kuwahara, Y1
Inatomi, N1
Inada, I1
Sino, A1
Maki, Y1
Labò, G1
Barbara, L1
Miglioli, M1
Di Febo, G1
Cornia, GL1
Corinaldesi, R1
Lami, F1
Palasz, M1
Bodin, F1
Conte, M1
Vasilenko, VKh1
Tsodikov, GV1
Minushkin, ON1
Delaveirre, PH1
Hureau, J1
Grivaux, M1
Chretien, J1
Etienne, JP1
Furnemont, E1
Fichera, G1
Mirelli, E1
Sun, DC1
Roth, SH1
Mitchell, CS1
Englund, DW1
Buchmann, E1

Reviews

4 reviews available for indomethacin and Curling Ulcer

ArticleYear
Prostaglandin E2 in intestinal secretion with special reference to methodological problems in vivo and in vitro.
    Danish medical bulletin, 1992, Volume: 39, Issue:2

    Topics: Adenoma; Animals; Cholera; Colonic Diseases, Functional; Diarrhea; Dinoprostone; Dose-Response Relat

1992
[Bicarbonate secretion in the mucosal defensive mechanism of the duodenum. Acid neutralization with HCO3- in the lumen and mucus gel].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1990, Volume: 110, Issue:2

    Topics: Animals; Bicarbonates; Duodenal Ulcer; Duodenum; Hydrogen-Ion Concentration; In Vitro Techniques; In

1990
[Effect of some drugs in the development and exacerbation of gastric and duodenal ulcer].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Jun-15, Volume: 27, Issue:12

    Topics: Adrenocorticotropic Hormone; Aspirin; Caffeine; Catecholamines; Duodenal Ulcer; Fluorouracil; Glucoc

1974
[Effect of some antirheumatic agents on the gastric mucous membrane].
    Klinicheskaia meditsina, 1971, Volume: 49, Issue:8

    Topics: Adrenocorticotropic Hormone; Aged; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheuma

1971

Trials

7 trials available for indomethacin and Curling Ulcer

ArticleYear
Sulglycotide in the prevention of nonsteroidal anti-inflammatory drug-induced gastroduodenal mucosal injury. A controlled double-blind, double-dummy, randomized endoscopic study versus placebo in rheumatic patients.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheu

1993
Healing with basic fibroblast growth factor is associated with reduced indomethacin induced relapse in a human model of gastric ulceration.
    Gut, 1997, Volume: 40, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cimetidine; Cross-Over S

1997
[Therapy of gastric and duodenal ulcer with Metoclopramide].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1976, Apr-30, Volume: 52, Issue:12

    Topics: Aged; Clinical Trials as Topic; Duodenal Ulcer; Female; Humans; Indomethacin; Male; Metoclopramide;

1976
A comparison of upper gastrointestinal mucosal damage by standard and delayed-release indomethacin.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Double-Blind Method; Duodenal Ulcer; Du

1992
[Stomach tolerance of nonsteroidal antirheumatic drugs: comparative endoscopic study].
    Zeitschrift fur Rheumatologie, 1987, Volume: 46 Suppl 1

    Topics: Adult; Alprostadil; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspiri

1987
Effect of fundic distension on gastric bicarbonate secretion in man.
    Scandinavian journal of gastroenterology, 1987, Volume: 22, Issue:5

    Topics: Adult; Aged; Bicarbonates; Duodenal Ulcer; Female; Gastric Juice; Humans; Indomethacin; Male; Middle

1987
Mefenamic acid compared with indomethacin and placebo in osteoarthritis.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Diarrhea; Digestion; Duodenal Ulcer; Female; Fol

1966

Other Studies

80 other studies available for indomethacin and Curling Ulcer

ArticleYear
Traditional Chinese Medicine prescription Huang-Qi-Jian-Zhong-Tang ameliorates indomethacin-induced duodenal ulcers in rats by affecting NF-κB and STAT signaling pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Animals; Cytokines; Drugs, Chinese Herbal; Duodenal Ulcer; Indomethacin; Medicine, Chinese Tradition

2022
Combined Effects of Medicinal Plants on Induced Upper Gastrointestinal Tract Injury in Wistar Rats.
    Ethiopian journal of health sciences, 2016, Volume: 26, Issue:6

    Topics: Aloe; Animals; Brassica; Dose-Response Relationship, Drug; Duodenal Ulcer; Female; Garlic; Indometha

2016
Polysaccharides derived from Ganoderma lucidum fungus mycelia ameliorate indomethacin-induced small intestinal injury via induction of GM-CSF from macrophages.
    Cellular immunology, 2017, Volume: 320

    Topics: Adoptive Transfer; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Complex Mixtur

2017
Anti-ulcerogenic activity of aqueous extract of Carica papaya seed on indomethacin-induced peptic ulcer in male albino rats.
    Journal of integrative medicine, 2015, Volume: 13, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Carica; Disease Models, Animal; Dose-Response Relationship, Drug; Duoden

2015
Role of dietary fibres, intestinal hypermotility and leukotrienes in the pathogenesis of NSAID-induced small intestinal ulcers in cats.
    Gut, 2009, Volume: 58, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Diet; Dietary Fiber; Duodenal Ulcer; Eating;

2009
Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Disease Models, Animal; Duodena

2010
Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:4

    Topics: Acetylglucosaminidase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogens;

2010
Healing of duodenal ulcers is not impaired by indomethacin or rofecoxib, the selective COX-2 inhibitor, in rats.
    Digestion, 2002, Volume: 66, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Duodenal Ulcer; Enzyme

2002
[Gastrointestinal hemorrhages as complications of gastropathies associated with intake of nonsteroidal anti-inflammatory drugs].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:5

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenal Ulcer; Duodeno

2003
Effect of exogenous administration of transforming growth factor-beta and famotidine on the healing of duodenal ulcer under the impact of indomethacin.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35, Issue:6

    Topics: Animals; Duodenal Ulcer; Famotidine; Gastric Acid; Indomethacin; Male; Rats; Rats, Wistar; Transform

2003
Involvement of nitric oxide in the gastroprotective effects of an aqueous extract of Pfaffia glomerata (Spreng) Pedersen, Amaranthaceae, in rats.
    Life sciences, 2004, Jan-16, Volume: 74, Issue:9

    Topics: Amaranthaceae; Animals; Brazil; Duodenal Ulcer; Gastric Acidity Determination; Hypothermia, Induced;

2004
Gastric antisecretory and anti-ulcer effect of ME3407, a new benzimidazole derivative, in rats.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Cysteamine; Duodenal

2004
Antiulcer activity of methanol fraction of Barleria lupulina Lindl. in animal models.
    Phytotherapy research : PTR, 2004, Volume: 18, Issue:11

    Topics: Acanthaceae; Animals; Anti-Ulcer Agents; Duodenal Ulcer; Ethanol; Female; Gastric Mucosa; Indomethac

2004
Antiulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania laevigata Schultz Bip.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2005, Volume: 12, Issue:1-2

    Topics: Animals; Anti-Ulcer Agents; Anticoagulants; Coumarins; Disease Models, Animal; Dose-Response Relatio

2005
Role of endogenous nitric oxide (NO) and NO synthases in healing of indomethacin-induced intestinal ulcers in rats.
    Life sciences, 2007, Jan-02, Volume: 80, Issue:4

    Topics: Animals; Disease Models, Animal; Duodenal Ulcer; Enzyme Inhibitors; Gene Expression Regulation, Enzy

2007
An herbal medicine orengedokuto prevents indomethacin-induced enteropathy.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Re

2007
Gastric cytoprotective properties of SCH 32651, a novel antiulcer agent.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 270, Issue:1

    Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cysteamine; Drug Evaluation, Preclinical; Duoden

1984
Prostaglandins in peptic ulcer disease: effect of nonsteroidal anti-inflammatory compounds (NOSAC).
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 92

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Carbazoles; Duodenal Ulcer; Gastric Mucosa; Humans; Indome

1984
Anti-ulcer activity and other pharmacological properties of lozilurea.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:12

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Dogs; Duodenal Ulcer; Female; Gastric Mucosa; Guinea Pigs; Hexo

1983
Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats.
    Digestive diseases and sciences, 1984, Volume: 29, Issue:5

    Topics: Animals; Aspirin; Benzimidazoles; Chemical Phenomena; Chemistry; Duodenal Ulcer; Epirizole; Gastric

1984
[Effects of SM powder, a combined herbal preparation for stomach diseases, on gastric secretion and acute gastro-duodenal lesions in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 81, Issue:4

    Topics: Animals; Aspirin; Depression, Chemical; Duodenal Ulcer; Ethanol; Gastric Juice; Immersion; Indometha

1983
Reintroduction of anti-inflammatory drug therapy after drug-associated gastro-intestinal disturbances.
    The New Zealand medical journal, 1982, Aug-25, Volume: 95, Issue:714

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Arthritis; Duodenal Ulcer; Female; Gastrointes

1982
Indomethacin and perforated duodenal ulcer.
    British medical journal, 1980, Feb-16, Volume: 280, Issue:6212

    Topics: Aged; Arthritis; Duodenal Ulcer; Female; Humans; Indomethacin; Middle Aged; Peptic Ulcer Perforation

1980
Indomethacin and perforated duodenal ulcer.
    British medical journal, 1980, Apr-19, Volume: 280, Issue:6221

    Topics: Duodenal Ulcer; Female; Humans; Indomethacin; Middle Aged; Peptic Ulcer Perforation

1980
Indomethacin and perforated duodenal ulcer.
    British medical journal, 1980, Jul-19, Volume: 281, Issue:6234

    Topics: Duodenal Ulcer; Humans; Indomethacin; Peptic Ulcer Perforation; Stomach Ulcer

1980
Indomethacin and perforated duodenal ulcer.
    British medical journal, 1980, Jun-28, Volume: 280, Issue:6231

    Topics: Duodenal Ulcer; Female; Humans; Indomethacin; Middle Aged; Peptic Ulcer Perforation; Stomach Ulcer

1980
Preventive effect of immunosuppressive agents against indomethacin-induced small intestinal ulcers in rats.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:4

    Topics: Animals; Cyclosporine; Duodenal Ulcer; Immunosuppressive Agents; Indomethacin; Intestine, Small; Mal

1994
YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Duodenal Ulcer; Epirizole; Ethanol; Famotidine; Gastric

1994
Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; Epirizole; Ethano

1993
An animal model of longitudinal ulcers in the small intestine induced by intracolonically administered indomethacin in rats.
    Gastroenterologia Japonica, 1993, Volume: 28, Issue:1

    Topics: Animals; Cecal Diseases; Colon; Disease Models, Animal; Duodenal Ulcer; Indomethacin; Intestinal Muc

1993
Studies on antiulcer agents. IV. Antiulcer effects of 2-benzylthio5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:11

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Epirizole;

1995
Ketotifen is protective against indomethacin-induced intestinal ulceration in the rat.
    Israel journal of medical sciences, 1996, Volume: 32, Issue:5

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models

1996
Effect of quinacrine, a phospholipase A2 inhibitor on stress and chemically induced gastroduodenal ulcers.
    Digestion, 1997, Volume: 58, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Cysteamine; Duodenal Ulcer; Enzyme Inhibitors; Ethanol; Female;

1997
Effects of selective cyclooxygenase-2 inhibitors on alkaline secretory and mucosal ulcerogenic responses in rat duodenum.
    Life sciences, 1997, Volume: 61, Issue:16

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Cyclooxygenase Inhibitors; Dinoprost

1997
Dual effect of female sex steroids on drug-induced gastroduodenal ulcers in the rat.
    Life sciences, 1999, Volume: 64, Issue:25

    Topics: Animals; Capillary Permeability; Cysteamine; Duodenal Ulcer; Estradiol; Female; Gastric Mucosa; Indo

1999
Protective effect of the nitric oxide donor molsidomine on indomethacin and aspirin-induced gastric injury in rats.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; Gas

2000
Protective effect of lafutidine against indomethacin-induced intestinal ulceration in rats: relation to capsaicin-sensitive sensory neurons.
    Digestion, 2000, Volume: 61, Issue:1

    Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Ampicillin; Animals; Capsaicin; Dose-Response Relationsh

2000
Keratinocyte growth factor-2 (FGF-10) promotes healing of experimental small intestinal ulceration in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:5

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Division; Chroni

2000
Effect of centrally administered prolactin on gastric and duodenal ulcers in rats.
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:3

    Topics: Acetic Acid; Animals; Chronic Disease; Cysteamine; Duodenal Ulcer; Ethanol; Gastric Acid; Gastric Ac

2001
Effect of hyperprolactinaemia as induced by pituitary homografts under kidney capsule on gastric and duodenal ulcers in rats.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:11

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cysteamine; Duodenal Ulcer; Gastric Acid; Hype

2001
Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs.
    Life sciences, 2001, Nov-21, Volume: 70, Issue:1

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Chronic Disease; Cysteamine; Disease Models,

2001
[Effect of exogenous administration of platelet-derived growth factor and epidermal growth factor on duodenal ulcer healing in rats treated with indomethacin].
    Gastroenterologia y hepatologia, 2002, Volume: 25, Issue:5

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Duodenal Ulcer; Ep

2002
Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:8

    Topics: Administration, Oral; Animals; Aspirin; Carbachol; Depression, Chemical; Disease Models, Animal; Duo

1977
Antiulcer activity of hypertonic solutions in the rat: possible role of prostaglandins.
    European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Cysteamine; Duodenal Ulcer; Female; Gastric Juice; Gastric Mucosa; Hydro

1979
[Multiple manifestations of intolerance of a combination of anti-inflammatory drugs. Role of phenylbutazone].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1975, Dec-09, Volume: 51, Issue:48

    Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Duodenal Ulcer; Erythema;

1975
Correlations of DNA, RNA and protein levels in duodenal mucosa with antiinflammatory potency and disposition to gut damage of non-steroidal agents. Comparative behaviour of glucametacine, indometacin, phenylbutazone and ibuprofen.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; DNA; Duodenal Ulcer; Duodenum; Female; Gastrointestinal Hemorrhag

1978
Resistance of the guinea pig to indomethacin ulcerogenesis.
    Toxicology and applied pharmacology, 1978, Volume: 45, Issue:2

    Topics: Animals; Drug Resistance; Duodenal Ulcer; Guinea Pigs; Indomethacin; Lethal Dose 50; Male; Peptic Ul

1978
Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs.
    Endoscopy, 1977, Volume: 9, Issue:3

    Topics: Aged; Anti-Inflammatory Agents; Aspirin; Diclofenac; Duodenal Ulcer; Endoscopy; Female; Fiber Optic

1977
Indomethacin-induced intestinal ulcers are associated with an increased number of peripheral T lymphocytes in the rat.
    International journal of tissue reactions, 1992, Volume: 14, Issue:6

    Topics: Animals; Duodenal Ulcer; Indomethacin; Leukocyte Count; Male; Rats; Rats, Sprague-Dawley; T-Lymphocy

1992
Effects of a new benzimidazole derivative, NC-1300-O-3, on gastric secretion and gastroduodenal lesions in rats.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benz

1991
BAY P 1455, a thiazolylaminobenzimidazole derivative with gastroprotective properties in the rat.
    European journal of pharmacology, 1991, Mar-26, Volume: 195, Issue:2

    Topics: Adrenalectomy; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Corticosterone; Cysteamine; D

1991
The effect of portal hypertension on indomethacin-induced small intestinal ulceration in the rat.
    Alimentary pharmacology & therapeutics, 1991, Volume: 5, Issue:1

    Topics: Animals; Duodenal Ulcer; Hypertension, Portal; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, In

1991
Effects of the new H2-receptor antagonist 3-amino-4-[4- [4- (1-piperidinomethyl)-2-pyridyloxy]-cis-2-butenylamino]-3-cyclobutene-1, 2- dione hydrochloride on gastric acid secretion and ulceration.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cold Temperature; Cysteamine; Duodenal Ulcer; Gastric Acid; Histamine; H

1990
Effect of nitrofurans on duodenal ulceration induced by cysteamine or indometacin.
    Pharmacology, 1991, Volume: 42, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cysteamine; Duodenal Ulcer; Female; Furazolidone; Indomethacin; Nitrofur

1991
Reduction of the severity of experimental gastric and duodenal ulceration by interleukin-1 beta.
    European journal of pharmacology, 1990, Sep-21, Volume: 186, Issue:2-3

    Topics: Animals; Cysteamine; Duodenal Ulcer; Ethanol; Indomethacin; Injections, Intraperitoneal; Interleukin

1990
Mucosal protective activity of activated aluminum complex.
    Digestion, 1990, Volume: 45, Issue:1

    Topics: Aluminum Hydroxide; Animals; Antacids; Aspirin; Cysteamine; Duodenal Ulcer; Ethanol; Gastric Mucosa;

1990
Human duodenal mucosal bicarbonate secretion--physiological and clinical aspects.
    Journal of internal medicine. Supplement, 1990, Volume: 732

    Topics: Acid-Base Equilibrium; Atropine; Bicarbonates; Biological Transport, Active; Duodenal Ulcer; Duodenu

1990
Modifications of gamma-glutamyl transpeptidase activity in duodenal mucosa of rats treated with different antiulcer drugs.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Duodenal Ulcer; Duodenum; Female; gamma-Glutamyltransferase; Indomethaci

1989
Effects of ALE-36 on gastric secretion, and gastric and duodenal ulcers induced in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: Animals; Benzimidazoles; Chlorides; Dose-Response Relationship, Drug; Duodenal Ulcer; Gastric Juice;

1989
Circadian rhythms of food intake in gastroduodenally-ulcerated rats: effects of three anti-ulcer drugs.
    Chronobiology international, 1989, Volume: 6, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Circadian Rhythm; Duodenal Ulcer; Eating; Female; Indomethacin; Male; Pi

1989
Healing process of duodenal ulcers induced by indomethacin plus histamine in rats.
    Digestion, 1989, Volume: 42, Issue:4

    Topics: Animals; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Gastric Acid; Histamine; Hydr

1989
Reduction of indomethacin induced gastroduodenal mucosal injury and gastrointestinal symptoms with cimetidine in normal subjects.
    The Journal of rheumatology, 1989, Volume: 16, Issue:9

    Topics: Adolescent; Adult; Cimetidine; Digestive System; Duodenal Ulcer; Duodenum; Female; Gastric Mucosa; H

1989
Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer.
    Lancet (London, England), 1986, Mar-01, Volume: 1, Issue:8479

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Duodenal Ulcer; Female; Humans; Ibuprofen; Indome

1986
Role of endogenous prostaglandins in duodenal ulcer formation.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Carbachol; Dinoprostone; Duodenal Ulcer; Female; Gastric Ju

1987
Intractable gouty arthritis.
    Hospital practice (Office ed.), 1987, Jun-15, Volume: 22, Issue:6

    Topics: Allopurinol; Arthritis; Colchicine; Duodenal Ulcer; Gout; Humans; Hypertension; Indomethacin; Male;

1987
Duodenal ulcers induced by indomethacin plus histamine in the dog. Involvement of the impaired duodenal alkaline secretion in their pathogenesis.
    Digestion, 1988, Volume: 39, Issue:4

    Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Dogs; Duodenal Ulcer; Duodenum; Female; Gastric Acidit

1988
Pentagastrin protects the proximal small intestine against indomethacin-induced ulcers in the rat.
    Digestion, 1987, Volume: 38, Issue:3

    Topics: Animals; Duodenal Ulcer; Indomethacin; Intestinal Mucosa; Male; Pentagastrin; Rats; Rats, Inbred Str

1987
A patient with unusual powers of recovery.
    The New Zealand medical journal, 1987, Jul-08, Volume: 100, Issue:827

    Topics: Aged; Duodenal Ulcer; Humans; Indomethacin; Male; Osteoarthritis; Peptic Ulcer Hemorrhage; Peptic Ul

1987
Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons.
    Gastroenterology, 1986, Volume: 91, Issue:4

    Topics: Animals; Capsaicin; Cysteamine; Dinoprostone; Duodenal Ulcer; Epoprostenol; Ethanol; Female; Gastric

1986
Gastric and duodenal antiulcer and cytoprotective effects of proglumide in rats.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: Animals; Cell Survival; Cimetidine; Cysteamine; Duodenal Ulcer; Female; Gastric Acid; Gastric Mucosa

1987
Prostaglandin deficiency by itself is not the cause of mepirizole-induced duodenal ulcers in rats.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:9

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Dose-Response Relationship, Drug; Drug Interactions; Duoden

1987
Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:4

    Topics: Animals; Cysteamine; Disease Models, Animal; Drug Synergism; Duodenal Ulcer; Epirizole; Histamine; I

1986
A new model of duodenal ulcers induced in rats by indomethacin plus histamine.
    Gastroenterology, 1986, Volume: 90, Issue:3

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Bicarbonates; Cimetidine; Dose-Response Relationship, Drug;

1986
Effects of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one, a new anti-ulcer agent, on experimental acute and chronic ulcers.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:10

    Topics: Acetates; Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Aspirin; Benzofurans; Chronic Dise

1985
[Gastroduodenal ulcer: pathogenetic and clinical aspects].
    Minerva medica, 1974, Sep-15, Volume: 65, Issue:64

    Topics: Alcoholic Beverages; Diet; Duodenal Ulcer; Gastric Juice; Gastrins; Gastrointestinal Hormones; Hista

1974
[Digestive tract hemorrhages following ingestion of anti-inflammatory drugs].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Mar-20, Volume: 45, Issue:14

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Duodenal Ulcer; Female; Gastrointestinal He

1969
[Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Nov-20, Volume: 49, Issue:47

    Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Duodenal Ulcer; Female; Humans; In

1973
[Ulcers of the gastroduodenal tract due to drugs. Apropos of a personal experience].
    Acta gastro-enterologica Belgica, 1972, Volume: 35, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Aspirin; Duodenal Ulcer; Female; Gastrointestinal

1972
[Gastro-duodenal tolerance of some drugs with analgesic effect. Clinico-endoscopic considerations].
    Minerva medica, 1974, Feb-24, Volume: 65, Issue:14

    Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Digestive System; Duodenal Ulcer; Esop

1974
Upper gastrointestinal disease in rheumatoid arthritis.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Arizona; Arthritis, Rheumatoid; Aspir

1974