Page last updated: 2024-10-29

indomethacin and Coxsackie Virus Infections

indomethacin has been researched along with Coxsackie Virus Infections in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin has been shown to increase virus titers and to worsen cardiac injury in the acute phase of coxsackievirus B4 murine myocarditis."7.68Focal ventricular thinning caused by indomethacin in the late phase of coxsackievirus B4 murine myocarditis. ( Khatib, G; Khatib, R; Kloner, RA; Reyes, MP; Rezkella, S; Smith, F, 1992)
"Previous studies have shown that indomethacin administered during the early phase of experimental myocarditis may exacerbate the disease process."7.67Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model. ( Khatib, G; Khatib, R; Kloner, R; Rezkalla, S; Smith, F; Sowers, J; Walsh, M, 1988)
"Indomethacin has been shown to increase virus titers and to worsen cardiac injury in the acute phase of coxsackievirus B4 murine myocarditis."3.68Focal ventricular thinning caused by indomethacin in the late phase of coxsackievirus B4 murine myocarditis. ( Khatib, G; Khatib, R; Kloner, RA; Reyes, MP; Rezkella, S; Smith, F, 1992)
"The effect of salicylates or indomethacin usage during viral infection was investigated in a murine model of coxsackievirus B3 myocarditis."3.67Coxsackievirus B3 murine myocarditis: deleterious effects of nonsteroidal anti-inflammatory agents. ( Khatib, G; Khatib, R; Rezkalla, S, 1986)
"Previous studies have shown that indomethacin administered during the early phase of experimental myocarditis may exacerbate the disease process."3.67Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model. ( Khatib, G; Khatib, R; Kloner, R; Rezkalla, S; Smith, F; Sowers, J; Walsh, M, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khatib, R4
Reyes, MP2
Khatib, G4
Smith, F3
Rezkella, S1
Kloner, RA1
Rezkalla, S3
Walsh, M1
Sowers, J1
Kloner, R1

Other Studies

4 other studies available for indomethacin and Coxsackie Virus Infections

ArticleYear
Focal ventricular thinning caused by indomethacin in the late phase of coxsackievirus B4 murine myocarditis.
    The American journal of the medical sciences, 1992, Volume: 303, Issue:2

    Topics: Animals; Coxsackievirus Infections; Enterovirus B, Human; Heart; Indomethacin; Mice; Myocarditis; My

1992
Enhancement of coxsackievirus B4 virulence by indomethacin.
    The Journal of laboratory and clinical medicine, 1990, Volume: 116, Issue:1

    Topics: Animals; Antibodies, Viral; Coxsackievirus Infections; Disease Models, Animal; Enterovirus B, Human;

1990
Coxsackievirus B3 murine myocarditis: deleterious effects of nonsteroidal anti-inflammatory agents.
    The Journal of laboratory and clinical medicine, 1986, Volume: 107, Issue:4

    Topics: Animals; Antibodies, Viral; Coxsackievirus Infections; Indomethacin; Interferons; Mice; Myocarditis;

1986
Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model.
    The Journal of laboratory and clinical medicine, 1988, Volume: 112, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Chronic Disease; Coxsackievirus Infections; Disease Models, Anim

1988