indomethacin has been researched along with Cough in 22 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "day-1 for 4 days), on cough response to inhaled capsaicin were examined in eight patients with asthma, 10 patients with chronic bronchitis, and 10 normal subjects." | 9.08 | Prostanoids and cough response to capsaicin in asthma and chronic bronchitis. ( Bando, T; Fujimura, M; Hashimoto, T; Kamio, Y; Kasahara, K; Matsuda, T, 1995) |
| "Cough reflex testing with capsaicin has been used to study the pathophysiology of the cough reflex and the antitussive effects of various drugs." | 9.07 | Tachyphylaxis to capsaicin-induced cough and its reversal by indomethacin, in patients with the sinobronchial syndrome. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Sakamoto, S, 1992) |
| "At the end of each treatment phase, cough was evaluated by a self-administered questionnaire containing an ordinal scale for daily cough intensity and frequency." | 6.67 | Effects of nifedipine and indomethacin on cough induced by angiotensin-converting enzyme inhibitors: a double-blind, randomized, cross-over study. ( Fogari, R; Malamani, GD; Salvetti, A; Tettamanti, F; Tinelli, C; Zoppi, A, 1992) |
| "day-1 for 4 days), on cough response to inhaled capsaicin were examined in eight patients with asthma, 10 patients with chronic bronchitis, and 10 normal subjects." | 5.08 | Prostanoids and cough response to capsaicin in asthma and chronic bronchitis. ( Bando, T; Fujimura, M; Hashimoto, T; Kamio, Y; Kasahara, K; Matsuda, T, 1995) |
| "Cough reflex testing with capsaicin has been used to study the pathophysiology of the cough reflex and the antitussive effects of various drugs." | 5.07 | Tachyphylaxis to capsaicin-induced cough and its reversal by indomethacin, in patients with the sinobronchial syndrome. ( Bando, T; Fujimura, M; Kamio, Y; Matsuda, T; Myou, S; Sakamoto, S, 1992) |
| " We describe a patient with migraine without aura and exertional secondary headache due to Chiari malformation type I whose headaches responded to treatment with propranolol and indomethacin." | 3.72 | Chiari-associated exertional, cough, and sneeze headache responsive to medical therapy. ( Buzzi, MG; Colonnese, C; Formisano, R; Pierelli, F, 2003) |
| " In this study, in order to evaluate the cough and inflammatory reaction, we measured the number of citric acid-induced coughs and the intradermal inflammation with ovalbumin in guinea pigs consecutively treated with ACE inhibitors (lisinopril, enalaprilat and imidapril) for 3 days." | 3.69 | Toxicodynamic analysis of cough and inflammatory reactions by angiotensin-converting enzyme inhibitors in guinea pig. ( Iga, T; Ito, K; Kamei, J; Misawa, M; Sawada, Y, 1995) |
| "It has been suggested that bradykinin may play a role in stimulating cough in at least one pathological condition in humans." | 3.69 | Mechanism of irritant-induced cough: studies with a kinin antagonist and a kallikrein inhibitor. ( Church, MK; Evans, DM; Featherstone, RL; Jones, DM; Olsson, H; Parry, JE; Szelke, M, 1996) |
| "At the end of each treatment phase, cough was evaluated by a self-administered questionnaire containing an ordinal scale for daily cough intensity and frequency." | 2.67 | Effects of nifedipine and indomethacin on cough induced by angiotensin-converting enzyme inhibitors: a double-blind, randomized, cross-over study. ( Fogari, R; Malamani, GD; Salvetti, A; Tettamanti, F; Tinelli, C; Zoppi, A, 1992) |
| "It also may be the first cluster headache subtype that is indomethacin responsive." | 1.31 | Valsalva-induced cluster: a new subtype of cluster headache. ( Ko, J; Rozen, TD, 2002) |
| "Indomethacin is the treatment of choice of benign cough headache, but has no effect in symptomatic cases, which respond to suboccipital craniectomy." | 1.30 | [Headaches due to cough, exertion and sexual intercourse]. ( Berciano, J; Oterino, A; Pascual, J, 1997) |
| "Cough is an important side effect of Angiotensin Converting Enzyme Inhibitor (ACEI) therapy." | 1.30 | Angiotensin converting enzyme inhibitors and cough--a north Indian study. ( Agarwal, A; Anuradha, S; Rizvi, SN; Singh, NP; Uppal, M, 1998) |
| "Typical chronic paroxysmal hemicrania and cough headache episodes appeared independently and responded to indomethacin." | 1.30 | Coexistence of chronic paroxysmal hemicrania and benign cough headache. ( Mateo, I; Pascual, J, 1999) |
| "Cough was attributed to thyroiditis only after extensive diagnostic evaluations failed to uncover another cause and only after cough and thyroiditis disappeared simultaneously with suppressive therapy for the latter." | 1.26 | Chronic persistent cough: an uncommon presenting complaint of thyroiditis. ( Hamolsky, MW; Irwin, RS; Pratter, MR, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 12 (54.55) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pavão Martins, I | 1 |
| Viana, P | 1 |
| Pascual, J | 3 |
| González-Mandly, A | 1 |
| Martín, R | 1 |
| Oterino, A | 2 |
| Byard, E | 1 |
| Buzzi, MG | 1 |
| Formisano, R | 1 |
| Colonnese, C | 1 |
| Pierelli, F | 1 |
| Gatti, R | 1 |
| Andre, E | 1 |
| Amadesi, S | 1 |
| Dinh, TQ | 1 |
| Fischer, A | 1 |
| Bunnett, NW | 1 |
| Harrison, S | 1 |
| Geppetti, P | 1 |
| Trevisani, M | 1 |
| Irwin, RS | 1 |
| Pratter, MR | 1 |
| Hamolsky, MW | 1 |
| Ito, K | 2 |
| Sawada, Y | 1 |
| Kamei, J | 1 |
| Misawa, M | 1 |
| Iga, T | 1 |
| Bolser, DC | 1 |
| DeGennaro, FC | 1 |
| O'Reilly, S | 1 |
| Hey, JA | 1 |
| Chapman, RW | 1 |
| Moncada, E | 1 |
| Graff-Radford, SB | 1 |
| Fujimura, M | 2 |
| Kamio, Y | 2 |
| Kasahara, K | 1 |
| Bando, T | 2 |
| Hashimoto, T | 1 |
| Matsuda, T | 2 |
| Featherstone, RL | 1 |
| Parry, JE | 1 |
| Evans, DM | 1 |
| Jones, DM | 1 |
| Olsson, H | 1 |
| Szelke, M | 1 |
| Church, MK | 1 |
| Tyrakowski, T | 1 |
| Wojciechowska, I | 1 |
| Banach, B | 1 |
| Mościbroda, A | 1 |
| Greczko, I | 1 |
| Berciano, J | 1 |
| Ertsey, C | 1 |
| Jelencsik, I | 1 |
| Singh, NP | 1 |
| Uppal, M | 1 |
| Anuradha, S | 1 |
| Agarwal, A | 1 |
| Rizvi, SN | 1 |
| Mateo, I | 1 |
| Ko, J | 1 |
| Rozen, TD | 1 |
| Sakamoto, S | 1 |
| Myou, S | 1 |
| Fogari, R | 1 |
| Zoppi, A | 1 |
| Tettamanti, F | 1 |
| Malamani, GD | 1 |
| Tinelli, C | 1 |
| Salvetti, A | 1 |
| Karlsson, JA | 1 |
| Zackrisson, C | 1 |
| Lundberg, JM | 1 |
| Lorenzo, A | 1 |
| Colomés, L | 1 |
| Igual, J | 1 |
| Laveda, P | 1 |
| Sacks, PV | 1 |
| Kanarek, D | 1 |
2 reviews available for indomethacin and Cough
| Article | Year |
|---|---|
Exertional headaches. Misdiagnosis can have long-lasting effects.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cough; Diagnosis, Differential; Diagnostic Errors; Headache | 2000 |
Cough headache presenting as a toothache: a case report.
Topics: Cough; Headache; Humans; Indomethacin; Male; Middle Aged; Toothache | 1993 |
5 trials available for indomethacin and Cough
| Article | Year |
|---|---|
Headaches precipitated by cough, prolonged exercise or sexual activity: a prospective etiological and clinical study.
Topics: Adult; Cerebral Angiography; Cough; Cyclooxygenase Inhibitors; Exercise; Female; Follow-Up Studies; | 2008 |
Prostanoids and cough response to capsaicin in asthma and chronic bronchitis.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Capsaicin; Chronic Disease; Cough; Cro | 1995 |
Tachyphylaxis to capsaicin-induced cough and its reversal by indomethacin, in patients with the sinobronchial syndrome.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Capsaicin; Chronic Disease; Cough; Female; Humans; Indo | 1992 |
Effects of nifedipine and indomethacin on cough induced by angiotensin-converting enzyme inhibitors: a double-blind, randomized, cross-over study.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cough; Double-Blin | 1992 |
Treatment of acute pleuritic pain. Comparison between indomethacin and a placebo.
Topics: Analgesia; Clinical Trials as Topic; Cough; Evaluation Studies as Topic; Humans; Indomethacin; Pain; | 1973 |
15 other studies available for indomethacin and Cough
| Article | Year |
|---|---|
"Cough Hemicrania" - An Overlapping Form of Headache: Case Reports.
Topics: Cough; Cyclooxygenase Inhibitors; Female; Headache Disorders, Primary; Humans; Indomethacin; Male; M | 2017 |
Chiari-associated exertional, cough, and sneeze headache responsive to medical therapy.
Topics: Adrenergic beta-Antagonists; Arnold-Chiari Malformation; Cough; Female; Headache; Humans; Indomethac | 2003 |
Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs.
Topics: Animals; Capsaicin; Citric Acid; Cough; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibit | 2006 |
Chronic persistent cough: an uncommon presenting complaint of thyroiditis.
Topics: Adult; Chronic Disease; Cough; Female; Humans; Indomethacin; Male; Radionuclide Imaging; Thyroid (US | 1982 |
Toxicodynamic analysis of cough and inflammatory reactions by angiotensin-converting enzyme inhibitors in guinea pig.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cough; Cyclooxygenase Inhibitors; Enalaprilat; Fe | 1995 |
Pharmacological studies of allergic cough in the guinea pig.
Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsai | 1995 |
Mechanism of irritant-induced cough: studies with a kinin antagonist and a kallikrein inhibitor.
Topics: Administration, Inhalation; Animals; Bradykinin; Bradykinin Receptor Antagonists; Citric Acid; Codei | 1996 |
[Electrophysiologic studies of local ion transport changes in the tracheal wall in vitro].
Topics: Amiloride; Animals; Bumetanide; Chi-Square Distribution; Chlorides; Cough; Epithelium; Gagging; In V | 1997 |
[Headaches due to cough, exertion and sexual intercourse].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Angiography; Cerebral Arteries; Coitus; Cou | 1997 |
Cough headache associated with Chiari type-I malformation: responsiveness to indomethacin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arnold-Chiari Malformation; Cough; Female; Headache; Humans | 2000 |
Angiotensin converting enzyme inhibitors and cough--a north Indian study.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cough; Enalapril; Female; Follow-U | 1998 |
Coexistence of chronic paroxysmal hemicrania and benign cough headache.
Topics: Adult; Cough; Drug Therapy, Combination; Female; Headache; Humans; Indomethacin; Migraine Disorders; | 1999 |
Valsalva-induced cluster: a new subtype of cluster headache.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cough; Humans; I | 2002 |
Hyperresponsiveness to tussive stimuli in cigarette smoke-exposed guinea-pigs: a role for capsaicin-sensitive, calcitonin gene-related peptide-containing nerves.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Cough; Female; Guinea Pigs; Indomethac | 1991 |
[Treatment of captopril-induced cough].
Topics: Aged; Captopril; Cough; Humans; Indomethacin; Middle Aged | 1989 |