indomethacin has been researched along with Coronary Vasospasm in 8 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both patients exhibited anaphylactic manifestations, such as general rash and urticaria, along with angina pectoris with electrocardiographic ST-segment elevations after suppository administration of diclofenac sodium or indomethacin, the most commonly used NSAIDs." | 3.69 | Vasospastic angina induced by nonsteroidal anti-inflammatory drugs. ( Eguchi, H; Haramaki, N; Hashino, T; Ichiki, K; Ikeda, H; Imaizumi, T; Kai, H; Katoh, A; Mori, E; Ueno, T; Ueyama, T, 1997) |
| " The administration of intravenous ergonovine did not provoke ST-segment shifts or arrhythmias." | 3.67 | Coronary artery spasm after abrupt withdrawal of nitroglycerin in rabbits. ( Cook, L; Reeves, WC; Whitesell, L; Wood, MA, 1985) |
| "In 67 dogs with a 60-80% coronary stenosis produced by an external constricting plastic ring, blood flow measured with an electromagnetic flowmeter showed cyclical flow reductions of varying magnitude and duration, and then an abrupt return to control flow." | 1.26 | Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation? ( Folts, JD; Gallagher, K; Rowe, GG, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Folts, JD | 1 |
| Gallagher, K | 1 |
| Rowe, GG | 1 |
| Mori, E | 1 |
| Ikeda, H | 1 |
| Ueno, T | 1 |
| Kai, H | 1 |
| Haramaki, N | 1 |
| Hashino, T | 1 |
| Ichiki, K | 1 |
| Katoh, A | 1 |
| Eguchi, H | 1 |
| Ueyama, T | 1 |
| Imaizumi, T | 1 |
| Zou, MH | 1 |
| Bachschmid, M | 1 |
| Egashira, K | 1 |
| Tomoike, H | 3 |
| Hayashi, Y | 1 |
| Yamada, A | 1 |
| Nakamura, M | 3 |
| Takeshita, A | 1 |
| Shimokawa, H | 2 |
| Booth, DC | 1 |
| Cunningham, MR | 1 |
| Rountree, RM | 1 |
| Elion, J | 1 |
| Nissen, SE | 1 |
| Gillespie, MN | 1 |
| Nabeyama, S | 1 |
| Yamamoto, H | 1 |
| Reeves, WC | 1 |
| Cook, L | 1 |
| Wood, MA | 1 |
| Whitesell, L | 1 |
8 other studies available for indomethacin and Coronary Vasospasm
| Article | Year |
|---|---|
Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation?
Topics: Animals; Aspirin; Constriction, Pathologic; Coronary Angiography; Coronary Circulation; Coronary Dis | 1982 |
Vasospastic angina induced by nonsteroidal anti-inflammatory drugs.
Topics: Aged; Angina Pectoris; Anti-Inflammatory Agents, Non-Steroidal; Coronary Angiography; Coronary Vasos | 1997 |
Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds, Heteroc | 1999 |
Mechanism of ergonovine-induced hyperconstriction of the large epicardial coronary artery in conscious dogs a month after arterial injury.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Diltiazem; Dogs | 1992 |
Effects of prostacyclin, indomethacin, and thiothromboxane A2 on histamine-induced coronary spasm in atherosclerotic miniature swine.
Topics: Animals; Arteriosclerosis; Coronary Vasospasm; Disease Models, Animal; Epoprostenol; Histamine; Indo | 1985 |
Coronary arteriography in the intact rabbit: demonstration of coronary vasomotor and electrocardiographic effects of ergonovine and indomethacin in rabbits after abrupt cessation of prolonged nitroglycerin treatment.
Topics: Animals; Arrhythmias, Cardiac; Cineangiography; Coronary Angiography; Coronary Vasospasm; Coronary V | 1987 |
Histamine-induced spasm not significantly modulated by prostanoids in a swine model of coronary artery spasm.
Topics: Animals; Arteriosclerosis; Body Weight; Cholesterol; Coronary Vasospasm; Disease Models, Animal; Epo | 1985 |
Coronary artery spasm after abrupt withdrawal of nitroglycerin in rabbits.
Topics: Animals; Arrhythmias, Cardiac; Coronary Vasospasm; Electrocardiography; Ergonovine; Humans; Indometh | 1985 |