Page last updated: 2024-10-29

indomethacin and Corneal Ulcer

indomethacin has been researched along with Corneal Ulcer in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Corneal Ulcer: Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.

Research Excerpts

ExcerptRelevanceReference
"Topical indomethacin is worthy of further trial and investigation in the management of the Albury-Wodonga syndrome, harvester's eye, Christmas eye or seasonal corneal ulcer."3.69The Albury-Wodonga syndrome. A tale of two cities. ( Howsam, G, 1995)
" Medroxyprogesterone acetate also affected the development of corneal ulcers postalkali burn, but in a less well-defined manner."3.65Endocrine influences on ulceration and regeneration in the alkali-burned cornea. ( Crabb, CV, 1977)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Howsam, G1
Crabb, CV1
Maĭchuk, IuF1
Kazachenko, MA1
Diadina, UV1
Struck, HG1
Franke, C1
Tost, M1
Taube, C1

Trials

1 trial available for indomethacin and Corneal Ulcer

ArticleYear
[Animal experiment and clinical studies of the use of anti-inflammatory agents in chemical burns of the eye].
    Klinische Monatsblatter fur Augenheilkunde, 1988, Volume: 193, Issue:4

    Topics: Animals; Burns, Chemical; Corneal Ulcer; Dexamethasone; Eye Burns; Female; Humans; Indomethacin; Mal

1988

Other Studies

3 other studies available for indomethacin and Corneal Ulcer

ArticleYear
The Albury-Wodonga syndrome. A tale of two cities.
    Australian and New Zealand journal of ophthalmology, 1995, Volume: 23, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Presc

1995
Endocrine influences on ulceration and regeneration in the alkali-burned cornea.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1977, Volume: 95, Issue:10

    Topics: Alkalies; Animals; Bucladesine; Burns, Chemical; Corneal Injuries; Corneal Ulcer; Indomethacin; Medr

1977
[Rengasil (pirprofen) in the treatment of inflammatory eye diseases].
    Oftalmologicheskii zhurnal, 1990, Issue:5

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Corneal Ulcer; Drug Evaluation; Human

1990