indomethacin has been researched along with Corneal Neovascularization in 3 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Corneal Neovascularization: New blood vessels originating from the corneal blood vessels and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to evaluate the ability of topically applied CAPE in comparison with known steroidal (dexamethasone sodium phosphate) and nonsteroidal (indomethacin) topical agents to reduce corneal neovascularization (CNV) induced by silver nitrate cauterization in rats." | 7.71 | Effect of caffeic acid phenethyl ester on corneal neovascularization in rats. ( Aydin, E; Borazan, M; Cekiç, O; Cihan Dağloğlu, M; Dağlioğlu, K; Gültek, A; Totan, Y, 2001) |
| " We aimed to evaluate the ability of topically applied CAPE in comparison with known steroidal (dexamethasone sodium phosphate) and nonsteroidal (indomethacin) topical agents to reduce corneal neovascularization (CNV) induced by silver nitrate cauterization in rats." | 3.71 | Effect of caffeic acid phenethyl ester on corneal neovascularization in rats. ( Aydin, E; Borazan, M; Cekiç, O; Cihan Dağloğlu, M; Dağlioğlu, K; Gültek, A; Totan, Y, 2001) |
| "Both NS-398 and indomethacin significantly inhibited corneal neovascularization with the % inhibition of 36." | 3.70 | The effect of selective cyclooxygenase-2 inhibitor on corneal angiogenesis in the rat. ( Kawai, M; Kawai, Y; Mashima, Y; Yamada, M, 1999) |
| "Corneal neovascularization was induced by alkaline cautery in Sprague-Dawley rats and measured after four days." | 1.32 | Effect of COX inhibitors on VEGF-induced retinal vascular leakage and experimental corneal and choroidal neovascularization. ( Castro, MR; Edelman, JL; Lutz, D, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castro, MR | 1 |
| Lutz, D | 1 |
| Edelman, JL | 1 |
| Yamada, M | 1 |
| Kawai, M | 1 |
| Kawai, Y | 1 |
| Mashima, Y | 1 |
| Totan, Y | 1 |
| Aydin, E | 1 |
| Cekiç, O | 1 |
| Cihan Dağloğlu, M | 1 |
| Borazan, M | 1 |
| Dağlioğlu, K | 1 |
| Gültek, A | 1 |
3 other studies available for indomethacin and Corneal Neovascularization
| Article | Year |
|---|---|
Effect of COX inhibitors on VEGF-induced retinal vascular leakage and experimental corneal and choroidal neovascularization.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Retinal Barrier; Choroidal Neovascularizatio | 2004 |
The effect of selective cyclooxygenase-2 inhibitor on corneal angiogenesis in the rat.
Topics: Administration, Topical; Animals; Cornea; Corneal Neovascularization; Cyclooxygenase 2; Cyclooxygena | 1999 |
Effect of caffeic acid phenethyl ester on corneal neovascularization in rats.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Aci | 2001 |