indomethacin has been researched along with Corneal Injuries in 14 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Corneal Injuries: Damage or trauma inflicted to the CORNEA by external means.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our study highlighted the efficacy of indomethacin as a pain reducer for acute corneal pathology and suggested that the medication may act on the corneal nociceptors in a qualitative way." | 5.09 | Evaluation of the analgesic effect of 0.1% indomethacin solution on corneal abrasions. ( Macri, A; Patrone, G; Rolando, M; Sacca, SC, 1999) |
| " Medroxyprogesterone acetate also affected the development of corneal ulcers postalkali burn, but in a less well-defined manner." | 3.65 | Endocrine influences on ulceration and regeneration in the alkali-burned cornea. ( Crabb, CV, 1977) |
| "Traumatic corneal abrasions are relatively common and there is a lack of consensus about analgesia in their management." | 2.55 | Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions. ( Amayem, A; Brown, MD; Ghandour, O; Harrison, N; Lang, E; Lawrenson, AL; Lawrenson, JG; McCormick, R; Quirke, M; Wakai, A; Walsh, CD; Wang, Y, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wakai, A | 1 |
| Lawrenson, JG | 1 |
| Lawrenson, AL | 1 |
| Wang, Y | 1 |
| Brown, MD | 1 |
| Quirke, M | 1 |
| Ghandour, O | 1 |
| McCormick, R | 1 |
| Walsh, CD | 1 |
| Amayem, A | 1 |
| Lang, E | 1 |
| Harrison, N | 1 |
| Weaver, CS | 1 |
| Terrell, KM | 1 |
| Hanna, C | 1 |
| Keatts, HC | 1 |
| Rochels, R | 1 |
| Busse, WD | 1 |
| Srinivasan, BD | 3 |
| Kulkarni, PS | 3 |
| Eakins, KE | 1 |
| Laria, C | 1 |
| Alió, JL | 1 |
| Ruiz-Moreno, JM | 1 |
| Patrone, G | 1 |
| Sacca, SC | 1 |
| Macri, A | 1 |
| Rolando, M | 1 |
| Crabb, CV | 1 |
| Toczołowski, J | 1 |
| Robin, JB | 1 |
| Regis-Pacheco, LF | 1 |
| Kash, RL | 1 |
| Schanzlin, DJ | 1 |
| Schwartzkopff, T | 1 |
| Pahlitzsch, T | 1 |
| McDonald, TO | 1 |
| Borgmann, AR | 1 |
| Roberts, MD | 1 |
| Fox, LG | 1 |
2 reviews available for indomethacin and Corneal Injuries
| Article | Year |
|---|---|
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Corneal Injuries; Diclofenac; Flur | 2017 |
Evidence-based emergency medicine. Update: do ophthalmic nonsteroidal anti-inflammatory drugs reduce the pain associated with simple corneal abrasion without delaying healing?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Age | 2003 |
1 trial available for indomethacin and Corneal Injuries
| Article | Year |
|---|---|
Evaluation of the analgesic effect of 0.1% indomethacin solution on corneal abrasions.
Topics: Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Injuries; Eye Injuries; F | 1999 |
11 other studies available for indomethacin and Corneal Injuries
| Article | Year |
|---|---|
Indomethacin in ocular inflammation in rabbits.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Corneal Injuries; Eye Diseases; Hydrocor | 1967 |
[Experimental studies on the effect of prostaglandin and leukotriene synthesis inhibitors on epithelial regeneration of the cornea].
Topics: Animals; Anti-Inflammatory Agents; Benzenesulfonates; Chemotaxis, Leukocyte; Cornea; Corneal Injurie | 1983 |
Characterization of chemotactic factors in corneal wound healing.
Topics: Animals; Arachidonic Acids; Chemotaxis; Corneal Injuries; Indomethacin; Kinetics; Neutrophils; Prost | 1980 |
The role of arachidonic acid metabolites in the mediation of the polymorphonuclear leukocyte response following corneal injury.
Topics: Animals; Arachidonic Acids; Chemotaxis, Leukocyte; Cornea; Corneal Injuries; Indomethacin; Neutrophi | 1980 |
Combined non-steroidal therapy in experimental corneal injury.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns, Chemical; Cornea; | 1997 |
Endocrine influences on ulceration and regeneration in the alkali-burned cornea.
Topics: Alkalies; Animals; Bucladesine; Burns, Chemical; Corneal Injuries; Corneal Ulcer; Indomethacin; Medr | 1977 |
[Effect of drugs inhibiting prostaglandin activity on the appearance of leukocytes in the tears after experimental injury to the corneal epithelium].
Topics: Animals; Chemotaxis, Leukocyte; Corneal Injuries; Disease Models, Animal; Epithelium; Female; Ibupro | 1991 |
The histopathology of corneal neovascularization. Inhibitor effects.
Topics: Animals; Chemotaxis, Leukocyte; Cornea; Corneal Injuries; Disease Models, Animal; Electrocoagulation | 1985 |
[Inhibition of corneal wound healing by locally administered indomethacin].
Topics: Animals; Burns, Chemical; Cornea; Corneal Injuries; Eye Burns; Guinea Pigs; Indomethacin; Ophthalmic | 1987 |
Anti-inflammatory effects of ketoprofen in rabbit corneal epithelial wound model.
Topics: Animals; Ciliary Body; Conjunctiva; Corneal Injuries; Dose-Response Relationship, Drug; Indomethacin | 1985 |
Corneal wound healing. I. Inhibition of stromal healing by three dexamethasone derivatives.
Topics: Alcohols; Animals; Corneal Injuries; Dexamethasone; Indomethacin; Pharmaceutical Vehicles; Phenylbut | 1970 |