Page last updated: 2024-10-29

indomethacin and Conus Medullaris Syndrome

indomethacin has been researched along with Conus Medullaris Syndrome in 6 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Edema formation and prostanoid production (prostaglandin E2 (PGE2), thromboxane B2 (TXB2), and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha) were studied in a model of neoplastic epidural cord compression (NSCC) in rats harboring a thoracolumbar tumor."7.67Indomethacin and dexamethasone treatment in experimental neoplastic spinal cord compression: Part 2. Effect on edema and prostaglandin synthesis. ( Shapira, Y; Shohami, E; Siegal, T, 1988)
"Edema formation and prostanoid production (prostaglandin E2 (PGE2), thromboxane B2 (TXB2), and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha) were studied in a model of neoplastic epidural cord compression (NSCC) in rats harboring a thoracolumbar tumor."3.67Indomethacin and dexamethasone treatment in experimental neoplastic spinal cord compression: Part 2. Effect on edema and prostaglandin synthesis. ( Shapira, Y; Shohami, E; Siegal, T, 1988)
"Multifocal bone Langerhans cell histiocytosis (LCH) is usually treated with prednisolone and vinblastine."1.51Thoracic spine Langerhans cell histiocytosis in a child with achondroplasia. ( Chan, Z; Gallo, P; Simpson, L, 2019)
"Treatment with indomethacin (10 mg/kg q 12 hr x 3) reduced both elevated water content and specific gravity values back to normal levels."1.27Indomethacin and dexamethasone treatment in experimental neoplastic spinal cord compression: Part 1. Effect on water content and specific gravity. ( Catane, R; Sandbank, U; Shapira, Y; Siegal, T, 1988)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, Z1
Simpson, L1
Gallo, P1
Taoka, Y1
Okajima, K1
Uchiba, M1
Siegal, T8
Lossos, F1
Shohami, E2
Shapira, Y3
Sandbank, U1
Catane, R1

Other Studies

6 other studies available for indomethacin and Conus Medullaris Syndrome

ArticleYear
Thoracic spine Langerhans cell histiocytosis in a child with achondroplasia.
    BMJ case reports, 2019, Jul-24, Volume: 12, Issue:7

    Topics: Achondroplasia; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Braces; Child; Conservative Trea

2019
Antithrombin reduces compression-induced spinal cord injury in rats.
    Journal of neurotrauma, 2004, Volume: 21, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Endothelial C

2004
Experimental neoplastic spinal cord compression: effect of anti-inflammatory agents and glutamate receptor antagonists on vascular permeability.
    Neurosurgery, 1990, Volume: 26, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Dexamethasone; Dibenzocycloheptenes; Dizo

1990
Indomethacin and dexamethasone treatment in experimental neoplastic spinal cord compression: Part 2. Effect on edema and prostaglandin synthesis.
    Neurosurgery, 1988, Volume: 22, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Water; Dexamethasone; Dinoprostone; Edema; Indomethacin;

1988
Comparison of soluble dexamethasone sodium phosphate with free dexamethasone and indomethacin in treatment of experimental neoplastic spinal cord compression.
    Spine, 1988, Volume: 13, Issue:10

    Topics: Animals; Body Water; Cervical Vertebrae; Dexamethasone; Dinoprostone; Indomethacin; Rats; Rats, Inbr

1988
Indomethacin and dexamethasone treatment in experimental neoplastic spinal cord compression: Part 1. Effect on water content and specific gravity.
    Neurosurgery, 1988, Volume: 22, Issue:2

    Topics: Animals; Body Water; Dexamethasone; Edema; Indomethacin; Rats; Rats, Inbred F344; Specific Gravity;

1988