indomethacin has been researched along with Compensatory Hyperinsulinemia in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin treatment improved these alterations." | 1.38 | Improvement of metabolic parameters and vascular function by metformin in obese non-diabetic rats. ( Akamine, EH; Carvalho, MH; Filgueira, FP; Fortes, ZB; Hagihara, GN; Lobato, NS; Pariz, JR; Tostes, RC, 2012) |
| "Pretreatment with indomethacin (3 mg/kg body weight), however, completely blocked the interleukin-1-induced stimulation of insulin secretion." | 1.28 | Indomethacin reverses interleukin-1-induced hyperinsulinemia in conscious and freely moving rats. ( Kumei, Y; Namiki, M; Okumura, T; Takasugi, Y; Uehara, A, 1991) |
| "Moreover, the hyperinsulinemia is mediated in part by prostaglandins just like the well-studied febrile response." | 1.28 | Central interleukin 1-elicited hyperinsulinemia is mediated by prostaglandins but not autonomics. ( Cornell, RP, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lobato, NS | 1 |
| Filgueira, FP | 1 |
| Hagihara, GN | 1 |
| Akamine, EH | 1 |
| Pariz, JR | 1 |
| Tostes, RC | 1 |
| Carvalho, MH | 1 |
| Fortes, ZB | 1 |
| Kashiwagi, A | 1 |
| Shinozaki, K | 1 |
| Nishio, Y | 1 |
| Okamura, T | 1 |
| Toda, N | 1 |
| Kikkawa, R | 1 |
| Schusdziarra, V | 1 |
| Rouiller, D | 1 |
| Unger, RH | 1 |
| Uehara, A | 1 |
| Okumura, T | 1 |
| Kumei, Y | 1 |
| Takasugi, Y | 1 |
| Namiki, M | 1 |
| Cornell, RP | 1 |
5 other studies available for indomethacin and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Improvement of metabolic parameters and vascular function by metformin in obese non-diabetic rats.
Topics: Acetylcholine; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Dyslipidemias; Epoprost | 2012 |
Free radical production in endothelial cells as a pathogenetic factor for vascular dysfunction in the insulin resistance state.
Topics: Acetylcholine; Animals; Calcimycin; Endothelium, Vascular; Free Radicals; Fructose; Hyperinsulinism; | 1999 |
Sympathectomy and prostaglandin deficiency do not prevent gastrogenic hyperglycaemia and hyperinsulinaemia.
Topics: Animals; Blood Glucose; Dogs; Food; Gastrins; Glucagon; Hydrogen-Ion Concentration; Hydroxydopamines | 1979 |
Indomethacin reverses interleukin-1-induced hyperinsulinemia in conscious and freely moving rats.
Topics: Anesthesia; Animals; Dose-Response Relationship, Drug; Hyperinsulinism; Indomethacin; Insulin; Inter | 1991 |
Central interleukin 1-elicited hyperinsulinemia is mediated by prostaglandins but not autonomics.
Topics: Acetophenones; Adrenocorticotropic Hormone; Animals; Atropine; Autonomic Nervous System; Body Temper | 1989 |