indomethacin has been researched along with Colitis in 46 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ingestion of DON mycotoxin at concentrations representative of human real-world exposure worsened the development of indomethacin-induced enteritis and colitis-associated CRC in mice." | 8.31 | Low dose dietary contamination with deoxynivalenol mycotoxin exacerbates enteritis and colorectal cancer in mice. ( Beury, D; Body-Malapel, M; Caboche, S; Desai, MS; Djouina, M; Dubuquoy, L; Hot, D; Launay, D; Lecointe, K; Steimle, A; Vignal, C; Waxin, C, 2023) |
| " Indomethacin abolished the gross mucosal protective effect by 1% AA pretreatment in 8% AA-derived colitis in normal rats while the NS398 had no effect." | 7.72 | Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase. ( Asama, T; Chisato, N; Kasai, S; Kono, T; Ohara, K; Yoneda, M, 2003) |
| " We compared the effects of nimesulide, a preferential COX-2 inhibitor, with those of indomethacin, acetylsalicylic acid (ASA), and dexamethasone in a 24-h model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in the rat." | 7.71 | Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut. ( Kankuri, E; Korpela, R; Moilanen, E; Paakkari, I; Vaali, K; Vapaatalo, H, 2001) |
| " Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis." | 7.70 | Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999) |
| "Diffuse colitis was produced in rats by the intracolonic administration of 10% acetic acid." | 7.66 | Experimental colitis studied by colonoscopy in the rat: effect of indomethacin. ( Demers, LM; Mann, NS, 1983) |
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 5.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| "Indomethacin treatment prior to induction of colitis reduced endogenous mucosal PGE2 levels and exacerbated macroscopic ulceration and net fluid absorption." | 5.28 | Indomethacin worsens and a leukotriene biosynthesis inhibitor accelerates mucosal healing in rat colitis. ( Empey, LR; Fedorak, RN; Walker, K, 1992) |
| "Ingestion of DON mycotoxin at concentrations representative of human real-world exposure worsened the development of indomethacin-induced enteritis and colitis-associated CRC in mice." | 4.31 | Low dose dietary contamination with deoxynivalenol mycotoxin exacerbates enteritis and colorectal cancer in mice. ( Beury, D; Body-Malapel, M; Caboche, S; Desai, MS; Djouina, M; Dubuquoy, L; Hot, D; Launay, D; Lecointe, K; Steimle, A; Vignal, C; Waxin, C, 2023) |
| " Subsequently, its protective effect in indomethacin and iodoacetamide induced colitis in rats (45, 90, 180, 270 mg/kg) and acetic acid induced colitis in mice (65, 130, 250, 500 mg/kg) was assessed." | 3.77 | Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice. ( Jagtap, AG; Niphadkar, PV; Phadke, AS, 2011) |
| " Celecoxib (10, 20 and 40 mg/kg(-l)) was significantly more potent at aggravating ischemia-reperfusion injury as compared to nimesulide." | 3.73 | Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors. ( Malhotra, S; Nada, R; Pandhi, P; Shafiq, N, 2005) |
| "Strips from rabbits with colitis induced by 2,4,6-trinitrobenzenesulfonic acid (TNBS) were subjected to electrical field stimulation." | 3.72 | Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation. ( Depoortere, I; Peeters, TL; Thielemans, L; Thijs, T, 2003) |
| " Indomethacin abolished the gross mucosal protective effect by 1% AA pretreatment in 8% AA-derived colitis in normal rats while the NS398 had no effect." | 3.72 | Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase. ( Asama, T; Chisato, N; Kasai, S; Kono, T; Ohara, K; Yoneda, M, 2003) |
| " In in vivo indomethacin-induced rat ileitis, MED15 heals better than 5-aminosalicylic acid and sulfasalazine, as well as down-regulating intestinal wall myeloperoxidase content." | 3.72 | Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug. ( Belogi, L; Bettelli, E; Mezzadri, CM; Tubaro, E, 2003) |
| " We compared the effects of nimesulide, a preferential COX-2 inhibitor, with those of indomethacin, acetylsalicylic acid (ASA), and dexamethasone in a 24-h model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in the rat." | 3.71 | Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut. ( Kankuri, E; Korpela, R; Moilanen, E; Paakkari, I; Vaali, K; Vapaatalo, H, 2001) |
| " Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis." | 3.70 | Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999) |
| "Nimesulide significantly decreased the extent of colitis induced by acetic acid." | 3.70 | Cyclo-oxygenase-2 inhibitors ameliorate the severity of experimental colitis in rats. ( Cohen, P; Karmeli, F; Rachmilewitz, D, 2000) |
| "We measured daily food intake and body weight in rats before and after the induction of colitis by intrarectal administration of either 2,4,6-trinitrobenzenesulfonic acid in ethyl alcohol (TNBE) or 4% acetic acid (AA)." | 3.68 | On the suppression of food intake in experimental models of colitis in the rat. ( Collins, SM; Keenan, C; McHugh, KJ; Wallace, JL; Weingarten, HP, 1993) |
| "An ulcerative enterocolitis was induced in dogs by two drugs; cinchophen given intravenously or indomethacin given orally." | 3.66 | Ulcerative enterocolitis in dogs induced by drugs. ( Hetenyi, C; Orizaga, M; Rowsell, H; Stewart, TH, 1980) |
| "Diffuse colitis was produced in rats by the intracolonic administration of 10% acetic acid." | 3.66 | Experimental colitis studied by colonoscopy in the rat: effect of indomethacin. ( Demers, LM; Mann, NS, 1983) |
| "Colitis was induced by the intracolonic administration of 2,4,6-trinitrobenzene sulfonic acid in rats, reactivated 6 weeks later." | 1.35 | Chronic inflammation alters the contribution of neurokinin receptor subtypes to epithelial function in rat colon. ( Appleyard, CB; Morales, M; Santiago, C, 2008) |
| "Colitis was induced either by trinitrobenzene sulphonic acid or dextran sodium sulphate." | 1.34 | Bile synthesis in rat models of inflammatory bowel diseases. ( Adler, G; Bachem, M; Buttenschoen, K; Chiang, JY; Dikopoulos, N; Schmid, RM; Weidenbach, H, 2007) |
| "Colitis was induced by intracolonic administration of trinitrobenzene sulfonic acid." | 1.31 | Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis. ( Ajuebor, MN; Singh, A; Wallace, JL, 2000) |
| "Distal colitis is associated with abnormal myoelectrical activity in the noninflamed ileum of rats." | 1.30 | Altered myoelectrical activity in noninflamed ileum of rats with colitis induced by trinitrobenzene sulphonic acid. ( Aube, AC; Barbier, M; Cherbut, C; Galmiche, JP; Roze, C; Xing, JH, 1999) |
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 1.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| "Indomethacin treatment prior to induction of colitis reduced endogenous mucosal PGE2 levels and exacerbated macroscopic ulceration and net fluid absorption." | 1.28 | Indomethacin worsens and a leukotriene biosynthesis inhibitor accelerates mucosal healing in rat colitis. ( Empey, LR; Fedorak, RN; Walker, K, 1992) |
| "Patients with colitis or ileocolitis were more likely to suffer from ocular inflammation (23." | 1.28 | Ocular inflammation in Crohn's disease. ( Murray, AD; Salmon, JF; Wright, JP, 1991) |
| "Treatment with prednisone or 5-aminosalicylic acid reduced TXB2 levels in the chronic stage of the inflammatory disease and improved the morphological damage as assessed macroscopically and histologically." | 1.28 | Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis. ( Guarner, F; Malagelada, JR; Rodriguez, R; Salas, A; Vilaseca, J, 1990) |
| "Microscopic colitis is responsible for a proportion of cases of intractable diarrhoea of obscure origin and rectal and colonic biopsies sould be undertaken in such cases." | 1.26 | Microscopic colitis-a cause of chronic watery diarrhoea. ( Ball, JA; Dawson, AM; Kingham, JG; Levison, DA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (19.57) | 18.7374 |
| 1990's | 13 (28.26) | 18.2507 |
| 2000's | 15 (32.61) | 29.6817 |
| 2010's | 6 (13.04) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Djouina, M | 1 |
| Waxin, C | 1 |
| Caboche, S | 1 |
| Lecointe, K | 1 |
| Steimle, A | 1 |
| Beury, D | 1 |
| Desai, MS | 1 |
| Hot, D | 1 |
| Dubuquoy, L | 1 |
| Launay, D | 1 |
| Vignal, C | 1 |
| Body-Malapel, M | 1 |
| Yan, Y | 1 |
| Zhou, X | 1 |
| Guo, K | 1 |
| Zhou, F | 1 |
| Yang, H | 1 |
| Yasukawa, K | 1 |
| Taş, A | 1 |
| Celik, H | 1 |
| Ammori, JB | 1 |
| Zhang, WZ | 1 |
| Li, JY | 1 |
| Chai, BX | 1 |
| Mulholland, MW | 1 |
| Suenaert, P | 1 |
| Maerten, P | 1 |
| Van Assche, G | 1 |
| Van Driessche, W | 1 |
| Geboes, K | 1 |
| Bulteel, V | 1 |
| Simaels, J | 1 |
| Augustijns, P | 1 |
| Ceuppens, JL | 1 |
| Rutgeerts, P | 1 |
| Perrier, C | 1 |
| Takamura, T | 1 |
| Harama, D | 1 |
| Matsuoka, S | 1 |
| Shimokawa, N | 1 |
| Nakamura, Y | 1 |
| Okumura, K | 1 |
| Ogawa, H | 1 |
| Kitamura, M | 1 |
| Nakao, A | 1 |
| Zrieki, A | 1 |
| Farinotti, R | 1 |
| Buyse, M | 1 |
| Jiang, GL | 1 |
| Im, WB | 1 |
| Donde, Y | 1 |
| Wheeler, LA | 1 |
| Jagtap, AG | 1 |
| Niphadkar, PV | 1 |
| Phadke, AS | 1 |
| Depoortere, I | 1 |
| Thijs, T | 1 |
| Thielemans, L | 1 |
| Peeters, TL | 1 |
| Ohara, K | 1 |
| Kono, T | 1 |
| Chisato, N | 1 |
| Asama, T | 1 |
| Yoneda, M | 1 |
| Kasai, S | 1 |
| Tubaro, E | 1 |
| Belogi, L | 1 |
| Mezzadri, CM | 1 |
| Bettelli, E | 1 |
| Blassneck, K | 1 |
| Nusko, G | 1 |
| Niedobitek, G | 1 |
| Hahn, EG | 1 |
| Harsch, IA | 1 |
| Shafiq, N | 1 |
| Malhotra, S | 1 |
| Pandhi, P | 1 |
| Nada, R | 1 |
| Dikopoulos, N | 1 |
| Schmid, RM | 1 |
| Bachem, M | 1 |
| Buttenschoen, K | 1 |
| Adler, G | 1 |
| Chiang, JY | 1 |
| Weidenbach, H | 1 |
| Appleyard, CB | 1 |
| Morales, M | 1 |
| Santiago, C | 1 |
| Marchbank, T | 1 |
| Mahmood, A | 1 |
| Fitzgerald, AJ | 1 |
| Domin, J | 1 |
| Butler, M | 1 |
| Goodlad, RA | 1 |
| Elia, G | 1 |
| Cox, HM | 1 |
| van Heel, DA | 1 |
| Ghosh, S | 1 |
| Playford, RJ | 1 |
| Stewart, TH | 1 |
| Hetenyi, C | 1 |
| Rowsell, H | 1 |
| Orizaga, M | 1 |
| Kingham, JG | 1 |
| Levison, DA | 1 |
| Ball, JA | 1 |
| Dawson, AM | 1 |
| Mann, NS | 1 |
| Demers, LM | 1 |
| Musch, MW | 1 |
| Miller, RJ | 1 |
| Field, M | 1 |
| Siegel, MI | 1 |
| Hammerbeck, DM | 1 |
| Brown, DR | 1 |
| LeDuc, LE | 1 |
| Su, KC | 1 |
| Guth, E | 1 |
| Reedy, T | 1 |
| Guth, PH | 1 |
| McHugh, KJ | 1 |
| Weingarten, HP | 1 |
| Keenan, C | 1 |
| Wallace, JL | 3 |
| Collins, SM | 1 |
| Banerjee, A | 1 |
| Zunino, A | 1 |
| Morera, G | 1 |
| Mian, M | 1 |
| Paira, S | 1 |
| Aube, AC | 1 |
| Cherbut, C | 1 |
| Barbier, M | 1 |
| Xing, JH | 1 |
| Roze, C | 1 |
| Galmiche, JP | 1 |
| Constantopoulos, A | 1 |
| Ablin, J | 1 |
| Shalev, O | 1 |
| Okon, E | 1 |
| Karmeli, F | 2 |
| Rachmilewitz, D | 2 |
| Evans, SM | 1 |
| László, F | 1 |
| Whittle, BJ | 1 |
| Cohen, P | 1 |
| Ajuebor, MN | 1 |
| Singh, A | 1 |
| Oktar, BK | 1 |
| Ercan, F | 1 |
| Yeğen, BC | 1 |
| Alican, I | 1 |
| Guo, X | 1 |
| Liu, ES | 1 |
| Ko, JK | 1 |
| Wong, BC | 1 |
| Ye, Y | 1 |
| Lam, S | 1 |
| Cho, C | 1 |
| Kankuri, E | 1 |
| Vaali, K | 1 |
| Korpela, R | 1 |
| Paakkari, I | 1 |
| Vapaatalo, H | 1 |
| Moilanen, E | 1 |
| Namihisa, T | 1 |
| Yamaguchi, K | 1 |
| Kitami, N | 1 |
| Takazakura, Y | 1 |
| Yamada, T | 1 |
| Keenan, CM | 1 |
| Gale, D | 1 |
| Shoupe, TS | 1 |
| Empey, LR | 1 |
| Walker, K | 1 |
| Fedorak, RN | 1 |
| Hoshino, H | 1 |
| Sugiyama, S | 1 |
| Ohara, A | 1 |
| Goto, H | 1 |
| Tsukamoto, Y | 1 |
| Ozawa, T | 1 |
| Salmon, JF | 1 |
| Wright, JP | 1 |
| Murray, AD | 1 |
| Vilaseca, J | 1 |
| Salas, A | 1 |
| Guarner, F | 1 |
| Rodriguez, R | 1 |
| Malagelada, JR | 1 |
| Schumert, R | 1 |
| Nast, CC | 1 |
| Cominelli, F | 1 |
| Zipser, RD | 1 |
| Del Soldato, P | 1 |
| Campieri, M | 1 |
| Brignola, C | 1 |
| Bazzocchi, G | 1 |
| Gionchetti, P | 1 |
| Lanfranchi, GA | 1 |
| Tamba, M | 1 |
| O'Brien, WM | 1 |
| Bagby, GF | 1 |
| Akizuki, M | 1 |
| Fujimori, I | 1 |
| Katsu, M | 1 |
2 reviews available for indomethacin and Colitis
| Article | Year |
|---|---|
[Free Radical Production and Production Mechanism in the Early and Advanced Stages of Gastrointestinal Lesions].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Dextran Sulfate; Electron Spin Resonance | 2020 |
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; | 1985 |
1 trial available for indomethacin and Colitis
| Article | Year |
|---|---|
[Antipyretic effects of indomethacin in acute infectious diseases--a double blind test].
Topics: Adolescent; Adult; Aged; Cholecystitis; Colitis; Female; Fever; Humans; Indomethacin; Infections; Ma | 1971 |
43 other studies available for indomethacin and Colitis
| Article | Year |
|---|---|
Low dose dietary contamination with deoxynivalenol mycotoxin exacerbates enteritis and colorectal cancer in mice.
Topics: Animals; Colitis; Colorectal Neoplasms; Diet; Enteritis; Humans; Indomethacin; Mice; Mycotoxins | 2023 |
Chlorogenic Acid Protects Against Indomethacin-Induced Inflammation and Mucosa Damage by Decreasing
Topics: Animals; Bacteroides; Bacteroides Infections; Chlorogenic Acid; Colitis; Fecal Microbiota Transplant | 2020 |
Severe colitis due to indomethacin suppository.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Female; Humans; Indomethacin; Severity of I | 2013 |
Effects of ghrelin on neuronal survival in cells derived from dorsal motor nucleus of the vagus.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Colitis; Gastrointestinal Tract; Ghrelin; I | 2008 |
Effects of T cell-induced colonic inflammation on epithelial barrier function.
Topics: Adoptive Transfer; Animals; CD4-Positive T-Lymphocytes; Colitis; Female; Indomethacin; Interleukin-1 | 2010 |
Activation of the aryl hydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Cytochrome P-450 CYP1A1; Dextran Sulfate; Dinoprostone | 2010 |
Cyclooxygenase-2 inhibitors prevent trinitrobenzene sulfonic acid-induced P-glycoprotein up-regulation in vitro and in vivo.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Colitis; Cyclooxygen | 2010 |
Comparison of prostaglandin E2 receptor subtype 4 agonist and sulfasalazine in mouse colitis prevention and treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cell Proliferation; Colitis; Colon; D | 2010 |
Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice.
Topics: Acetic Acid; Animals; Bombax; Colitis; Disease Models, Animal; Female; India; Indomethacin; Inflamma | 2011 |
Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation.
Topics: Adenosine Triphosphate; Animals; Colitis; Cyclooxygenase Inhibitors; Electric Stimulation; Female; I | 2003 |
Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase.
Topics: Acetic Acid; Animals; Colitis; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Rela | 2003 |
Impact on the bowel of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.
Topics: Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; | 2003 |
[Chronic diarrhea caused by NSAIDs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Colitis; Collagen; Colonoscopy; D | 2004 |
Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors.
Topics: Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Gastric Mucosa; Gastrointestinal Tract; Indo | 2005 |
Bile synthesis in rat models of inflammatory bowel diseases.
Topics: Animals; Bile Acids and Salts; Colitis; Dextran Sulfate; Indomethacin; Inflammatory Bowel Diseases; | 2007 |
Chronic inflammation alters the contribution of neurokinin receptor subtypes to epithelial function in rat colon.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Benzamid | 2008 |
Human pancreatic secretory trypsin inhibitor stabilizes intestinal mucosa against noxious agents.
Topics: Animals; Carrier Proteins; Cell Line; Cell Movement; Cell Proliferation; Colitis; Dendritic Cells; D | 2007 |
Ulcerative enterocolitis in dogs induced by drugs.
Topics: Animals; Colitis; Dogs; Enteritis; Female; Indomethacin; Intestinal Diseases; Male; Peyer's Patches; | 1980 |
Microscopic colitis-a cause of chronic watery diarrhoea.
Topics: Adult; Chronic Disease; Colitis; Colon; Diarrhea; Female; Humans; Indomethacin; Male; Middle Aged; P | 1982 |
Experimental colitis studied by colonoscopy in the rat: effect of indomethacin.
Topics: Acetates; Acetic Acid; Animals; Biopsy; Colitis; Colon; Colonoscopy; Dinoprostone; Fiber Optic Techn | 1983 |
Stimulation of colonic secretion by lipoxygenase metabolites of arachidonic acid.
Topics: Animals; Arachidonic Acids; Bicarbonates; Chlorides; Colitis; Colon; Diarrhea; Hydroxyeicosatetraeno | 1982 |
Selective hyperresponsiveness to ovalbumin-induced epithelial transport in inflamed guinea pig distal colon.
Topics: Animals; Antigens; Chlorpheniramine; Colitis; Cyclooxygenase Inhibitors; Disease Models, Animal; Epi | 1993 |
Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats.
Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Benzoquinones; Colitis; Colon; Cyclooxygenase | 1993 |
On the suppression of food intake in experimental models of colitis in the rat.
Topics: Acetates; Acetic Acid; Administration, Rectal; Animals; Body Weight; Colitis; Eating; Indoles; Indom | 1993 |
Thromboxanes, indomethacin, and experimental colitis.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Indomethacin; Rats; Thro | 1993 |
Enteropathic arthritis in association with collagenous colitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Biopsy, Needle; Colitis; C | 1998 |
Altered myoelectrical activity in noninflamed ileum of rats with colitis induced by trinitrobenzene sulphonic acid.
Topics: Animals; Atropine; Colitis; Colon; Electromyography; Enzyme Inhibitors; Ileum; Indomethacin; Male; M | 1999 |
Colitis induced by interaction of cyclosporine A and non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Child; Colitis; Cyclosporine; Diclof | 1999 |
Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats.
Topics: Acetates; Administration, Oral; Animals; Colitis; Deferiprone; Disease Models, Animal; Gastric Mucos | 1999 |
Site-specific lesion formation, inflammation and inducible nitric oxide synthase expression by indomethacin in the rat intestine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Colitis; Enteritis; Enzyme | 2000 |
Cyclo-oxygenase-2 inhibitors ameliorate the severity of experimental colitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase Inhibitors; Disease Models | 2000 |
Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis.
Topics: Animals; Blotting, Western; Celecoxib; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclo | 2000 |
The effect of alpha-melanocyte stimulating hormone on colonic inflammation in the rat.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Colitis; Cyclo | 2000 |
Protective role of cyclooxygenase inhibitors in the adverse action of passive cigarette smoking on the initiation of experimental colitis in rats.
Topics: Animals; Blotting, Western; Colitis; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inh | 2001 |
Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut.
Topics: Acute Disease; Animals; Aspirin; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygen | 2001 |
[A case with acute colitis induced by drug detected through lymphocyte stimulation test (author's transl)].
Topics: Acute Disease; Adult; Ampicillin; Colitis; Drug Hypersensitivity; Humans; Indomethacin; Lymphocyte A | 1975 |
Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Dinoprostone; Drug Combinations; I | 1992 |
Indomethacin worsens and a leukotriene biosynthesis inhibitor accelerates mucosal healing in rat colitis.
Topics: Acetates; Animals; Body Fluids; Colitis; Dialysis; Dinoprostone; Indoles; Indomethacin; Intestinal M | 1992 |
Mechanism and prevention of chronic colonic inflammation with trinitrobenzene sulfonic acid in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Chronic Disease; Colitis; Colon; Cyclosporine; Diseas | 1992 |
Ocular inflammation in Crohn's disease.
Topics: Adolescent; Adult; Aged; Anterior Eye Segment; Anti-Inflammatory Agents, Non-Steroidal; Child; Colit | 1991 |
Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis.
Topics: 6-Ketoprostaglandin F1 alpha; Aminosalicylic Acids; Animals; Colitis; Dinoprostone; Indomethacin; Le | 1990 |
Effects of 16,16-dimethyl prostaglandin E2 and indomethacin on leukotriene B4 and inflammation in rabbit colitis.
Topics: Animals; Colitis; Colon; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Leukotriene B | 1988 |
A possible mechanism of action of sulfasalazine and 5-aminosalicylic acid in inflammatory bowel diseases: interaction with oxygen free radicals.
Topics: Aminosalicylic Acids; Animals; Chemical Phenomena; Chemistry; Colitis; Free Radicals; Humans; Indome | 1985 |