Page last updated: 2024-10-29

indomethacin and Classic Globoid Cell Leukodystrophy

indomethacin has been researched along with Classic Globoid Cell Leukodystrophy in 1 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Globoid cell leukodystrophy (GLD) or Krabbe disease is a neurodegenerative disorder caused by the deficiency of the lysosomal enzyme galactocerebrosidase (GALC)."1.35Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy. ( Abraham, RM; Curtis, M; Hooper, DC; Luzi, P; Rafi, MA; Wenger, DA, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luzi, P1
Abraham, RM1
Rafi, MA1
Curtis, M1
Hooper, DC1
Wenger, DA1

Other Studies

1 other study available for indomethacin and Classic Globoid Cell Leukodystrophy

ArticleYear
Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy.
    Brain research, 2009, Dec-01, Volume: 1300

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Apoptosis; Bio

2009