Page last updated: 2024-10-29

indomethacin and Cholera Infantum

indomethacin has been researched along with Cholera Infantum in 99 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"A double-blind, double-dummy, crossover study was carried out in 8 centres to compare the efficacy and tolerability of 'controlled-release' ketoprofen tablets (200 mg) with that of indomethacin suppositories (100 mg) in out-patients with definite or classical rheumatoid arthritis."9.07A double-blind comparison of oral ketoprofen 'controlled release' and indomethacin suppository in the treatment of rheumatoid arthritis with special regard to morning stiffness and pain on awakening. ( Leden, I; Rubin, B; Uddenfeldt, P, 1993)
"Despite a wide range of study designs, a multiplicity of international trials of diclofenac in osteoarthritis have disclosed similar results."9.06International experiences with diclofenac in osteoarthritis. ( Altman, R, 1986)
"The effectiveness of fenclofenac in the treatment of rheumatoid arthritis was compared in a crossover double-blind study of 30 patients with that of indometacin over a period of two weeks."9.05[Fenclofenac in the treatment of rheumatoid arthritis (author's transl)]. ( Bachmann, F, 1980)
"The efficacy of naproxen and indomethacin in the treatment of dysmenorrhea was compared in a double-blind, cross-over study."9.04Naproxen and indomethacin in the treatment of primary dysmenorrhea. ( Kajanoja, P; Vesanto, T, 1979)
"A double-blind cross-over trial was carried out in 50 patients with definite rheumatoid arthritis, in order to compare the effects of 300 mg/day of ketoprofen with those of 600 mg/day of phenylbutazone, e."9.04A double-blind cross-over study of ketoprofen and phenylbutazone in rheumatoid arthritis. ( Peltola, P, 1976)
"), in comparison with that of indomethacin was investigated in 30 patients with rheumatoid arthritis."9.04Clinical evaluation of ketoprofen (19.583 R.P.) in rheumatoid arthritis. Double-blind cross-over comparison with indomethacin. ( Fossgreen, J; Kirchheiner, B; Petersen, FO; Tophoj, E; Zachariae, E, 1976)
"During a double-blind, randomized study on 30 patients affected with classic or definite rheumatoid arthritis, the efficacy and safety of treatment with diftalone in a per oral dosage of 500 mg/day were compared with those of indomethacin given orally at doses of 50-75 mg/day initially and 100 mg/day subsequently, for a treatment period of 24 months."9.04Comparative clinical trial with a new substance, Diftalone, versus indomethacin in 30 patients affected with rheumatoid arthritis. ( Bröll, H; Dunky, A; Eberl, R; Tausch, G, 1976)
"To evaluate, for the first time, the efficacy of copper-indomethacin in the inhibition of aberrant crypt foci formation using the azoxymethane-induced adenocarcinoma model, to examine cell viability in the HCT-116 colorectal cancer cell line, gastrointestinal permeability, mitochondrial oxidative damage, and renal toxicity in rat models."7.76Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats. ( Bonin, AM; Davies, NM; Dillon, CT; Fukuda, C; Hambley, TW; Lay, PA; Teng, XW; Yáñez, JA, 2010)
"A retrospective study to compare the incidence of NEC, NEC-related gastrointestinal complications and isolated gastrointestinal perforation among premature infants treated for a PDA with either, indomethacin alone (I), surgical ligation alone (L), or indomethacin followed by surgical ligation (I-L)."7.72Necrotizing enterocolitis and gastrointestinal complications after indomethacin therapy and surgical ligation in premature infants with patent ductus arteriosus. ( Adams, JM; Adams, K; Baetiong, A; Chen, A; O'Donovan, DJ; Smith, EO; Weisman, LE, 2003)
"A double-blind, double-dummy, crossover study was carried out in 8 centres to compare the efficacy and tolerability of 'controlled-release' ketoprofen tablets (200 mg) with that of indomethacin suppositories (100 mg) in out-patients with definite or classical rheumatoid arthritis."5.07A double-blind comparison of oral ketoprofen 'controlled release' and indomethacin suppository in the treatment of rheumatoid arthritis with special regard to morning stiffness and pain on awakening. ( Leden, I; Rubin, B; Uddenfeldt, P, 1993)
"Despite a wide range of study designs, a multiplicity of international trials of diclofenac in osteoarthritis have disclosed similar results."5.06International experiences with diclofenac in osteoarthritis. ( Altman, R, 1986)
"Data collected from more than 1,800 patients with rheumatoid arthritis or degenerative joint disease in Phase 3 clinical studies of isoxicam (Maxicam) indicated that the drug is well tolerated on both a short-term and a long-term basis."5.05Evaluation of the safety of isoxicam. ( Burch, FX, 1985)
"The effectiveness of fenclofenac in the treatment of rheumatoid arthritis was compared in a crossover double-blind study of 30 patients with that of indometacin over a period of two weeks."5.05[Fenclofenac in the treatment of rheumatoid arthritis (author's transl)]. ( Bachmann, F, 1980)
"The efficacy of naproxen and indomethacin in the treatment of dysmenorrhea was compared in a double-blind, cross-over study."5.04Naproxen and indomethacin in the treatment of primary dysmenorrhea. ( Kajanoja, P; Vesanto, T, 1979)
"A double-blind cross-over trial was carried out in 50 patients with definite rheumatoid arthritis, in order to compare the effects of 300 mg/day of ketoprofen with those of 600 mg/day of phenylbutazone, e."5.04A double-blind cross-over study of ketoprofen and phenylbutazone in rheumatoid arthritis. ( Peltola, P, 1976)
"Ketoprofen (100 mg/day) and indomethacin (100 mg/day) were compared in a double-blind cross-over trial of four weeks duration in 46 patients with rheumatoid arthritis."5.04Ketoprofen -- a new anti-rheumatic agent. ( Burry, HC; Grahame, R, 1976)
"), in comparison with that of indomethacin was investigated in 30 patients with rheumatoid arthritis."5.04Clinical evaluation of ketoprofen (19.583 R.P.) in rheumatoid arthritis. Double-blind cross-over comparison with indomethacin. ( Fossgreen, J; Kirchheiner, B; Petersen, FO; Tophoj, E; Zachariae, E, 1976)
"During a double-blind, randomized study on 30 patients affected with classic or definite rheumatoid arthritis, the efficacy and safety of treatment with diftalone in a per oral dosage of 500 mg/day were compared with those of indomethacin given orally at doses of 50-75 mg/day initially and 100 mg/day subsequently, for a treatment period of 24 months."5.04Comparative clinical trial with a new substance, Diftalone, versus indomethacin in 30 patients affected with rheumatoid arthritis. ( Bröll, H; Dunky, A; Eberl, R; Tausch, G, 1976)
" lingzhi and its autodigested product (AD-GL) against gut inflammation and endogenous sepsis induced in mice by the oral administration of indomethacin (IND)."3.88Protection against Gut Inflammation and Sepsis in Mice by the Autodigested Product of the Lingzhi Medicinal Mushroom, Ganoderma lingzhi (Agaricomycetes). ( Adachi, Y; Igami, K; Ishibashi, KI; Ishimoto, Y; Ito, H; Miyazaki, T; Ohno, N; Yamanaka, D, 2018)
"To evaluate, for the first time, the efficacy of copper-indomethacin in the inhibition of aberrant crypt foci formation using the azoxymethane-induced adenocarcinoma model, to examine cell viability in the HCT-116 colorectal cancer cell line, gastrointestinal permeability, mitochondrial oxidative damage, and renal toxicity in rat models."3.76Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats. ( Bonin, AM; Davies, NM; Dillon, CT; Fukuda, C; Hambley, TW; Lay, PA; Teng, XW; Yáñez, JA, 2010)
"A retrospective study to compare the incidence of NEC, NEC-related gastrointestinal complications and isolated gastrointestinal perforation among premature infants treated for a PDA with either, indomethacin alone (I), surgical ligation alone (L), or indomethacin followed by surgical ligation (I-L)."3.72Necrotizing enterocolitis and gastrointestinal complications after indomethacin therapy and surgical ligation in premature infants with patent ductus arteriosus. ( Adams, JM; Adams, K; Baetiong, A; Chen, A; O'Donovan, DJ; Smith, EO; Weisman, LE, 2003)
"Indomethacin, a nonsteroidal anti-inflammatory drug, induces the formation of gastrointestinal ulceration both in experimental animals and in humans."3.68Structural and morphometric analysis of murine small intestine after indomethacin administration. ( Carr, KE; Ettarh, RR, 1993)
"Ankylosing spondylitis is a systemic rheumatic disorder characterized by inflammation of the spine, sacroiliac, and large peripheral joints."2.66Efficacy of diclofenac in ankylosing spondylitis. ( Calabro, JJ, 1986)
"Upper gastrointestinal haemorrhage and pseudomembranous colitis are potentially fatal manifestations of drug therapy."2.36Drug-induced gastrointestinal disease. ( Bramble, MG; Record, CO, 1978)
"Treatment with uric acid protected Caco-2 cells from indomethacin-induced oxidative stress, lipid peroxidation, and cytotoxicity."1.46Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. ( Furuhashi, H; Higashiyama, M; Hokari, R; Komoto, S; Kurihara, C; Maruta, K; Matsuo, H; Miura, S; Nagao, S; Narimatsu, K; Okada, Y; Sato, H; Shirakabe, K; Takajo, T; Tomita, K; Watanabe, C; Yasutake, Y; Yoshikawa, K, 2017)
"Quercetin was the most efficient in protecting against mitochondrial dysfunction; this could be due to its ability to enter cells and accumulate in mitochondria."1.38Differential protective effects of quercetin, resveratrol, rutin and epigallocatechin gallate against mitochondrial dysfunction induced by indomethacin in Caco-2 cells. ( Carrasco-Pozo, C; Gotteland, M; Mizgier, ML; Speisky, H, 2012)
"Indomethacin (25mg/kg) was administered orally by a single application to rat (Wistar Han II, 200-250g)."1.35Type and distribution of indomethacin-induced lesions in the gastrointestinal tract of rat. ( Bures, J; Kunes, M; Kvetina, J, 2009)
" This molecular modification may offer a general route to safer antiinflammatory agents, potentially suitable for chronic use in conditions such as neurodegenerative disorders."1.32Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity. ( Charitos, C; Doulgkeris, C; Galanakis, D; Gavalas, A; Kourounakis, AP; Kourounakis, PN; Kravaritou, C; Rekka, EA; Tsiakitzis, KC, 2004)
"This prospective study evaluated heterotopic ossification prophylaxis with indomethacin for 14 days in 201 consecutive patients undergoing total hip arthroplasty."1.30General short-term indomethacin prophylaxis to prevent heterotopic ossification in total hip arthroplasty. ( Frank, E; Hofmann, S; Metzenroth, H; Ritschl, P; Salzer, M; Trnka, HJ, 1999)
"CDH can be due to transformed migraine (TM), new daily persistent headache (NDPH), chronic tension-type headache, and HC."1.29Hemicrania continua and symptomatic medication overuse. ( Silberstein, SD; Young, WB, 1993)
" The plasma levels of IM after the oral administration of IM-OE and IM-BE were comparatively low compared with those after IM, with a small bioavailability (2."1.29Pharmacokinetics of indomethacin ester prodrugs: gastrointestinal and hepatic toxicity and the hydrolytic capacity of various tissues in rats. ( Iwaki, M; Muraoka, O; Nagai, T; Ogiso, T; Tanabe, G; Tanino, T; Ueda, Y, 1996)
" All marmosets given 12 mg/kg/day and one marmoset given 6 mg/kg/day died during the dosing period (within 20 days)."1.28Evaluation of the toxicity of indomethacin in a 4-week study, by oral route, in the marmoset (Callithrix jacchus). ( Conz, A; Galli, CL; Giachetti, C; Oberto, G, 1990)
" A preliminary bioavailability study of two of the lead structures is presented."1.27Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents. ( Blythin, DJ; Bober, LA; Chiu, PJ; Conn, DJ; Domalski, MS; Kaminski, JJ; Solomon, DM; Spitler, J; Verbiar, LL; Wong, SC, 1986)

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199057 (57.58)18.7374
1990's15 (15.15)18.2507
2000's17 (17.17)29.6817
2010's10 (10.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Walsh, DA1
Moran, HW1
Shamblee, DA1
Welstead, WJ1
Nolan, JC1
Sancilio, LF1
Graff, G1
Blythin, DJ1
Kaminski, JJ1
Domalski, MS1
Spitler, J1
Solomon, DM1
Conn, DJ1
Wong, SC1
Verbiar, LL1
Bober, LA1
Chiu, PJ1
Khanna, IK1
Weier, RM1
Yu, Y1
Xu, XD1
Koszyk, FJ1
Collins, PW1
Koboldt, CM1
Veenhuizen, AW1
Perkins, WE1
Casler, JJ1
Masferrer, JL1
Zhang, YY1
Gregory, SA1
Seibert, K1
Isakson, PC1
Kalgutkar, AS1
Crews, BC1
Rowlinson, SW1
Marnett, AB1
Kozak, KR1
Remmel, RP1
Marnett, LJ1
Galanakis, D1
Kourounakis, AP1
Tsiakitzis, KC1
Doulgkeris, C1
Rekka, EA1
Gavalas, A1
Kravaritou, C1
Charitos, C1
Kourounakis, PN1
Sharma, M1
Ray, SM1
Chamoun-Emanuelli, AM1
Bryan, LK1
Cohen, ND1
Tetrault, TL1
Szule, JA1
Barhoumi, R1
Whitfield-Cargile, CM1
Martini, S1
Aceti, A1
Galletti, S1
Beghetti, I1
Faldella, G1
Corvaglia, L1
Ishimoto, Y1
Ishibashi, KI1
Yamanaka, D1
Adachi, Y1
Ito, H1
Igami, K1
Miyazaki, T1
Ohno, N1
Yasutake, Y1
Tomita, K1
Higashiyama, M1
Furuhashi, H1
Shirakabe, K1
Takajo, T1
Maruta, K1
Sato, H1
Narimatsu, K1
Yoshikawa, K1
Okada, Y1
Kurihara, C1
Watanabe, C1
Komoto, S1
Nagao, S1
Matsuo, H1
Miura, S1
Hokari, R1
Fawole, OA1
Ndhlala, AR1
Amoo, SO1
Finnie, JF1
Van Staden, J1
Kunes, M2
Kvetina, J2
Bures, J2
Bonin, AM1
Yáñez, JA1
Fukuda, C1
Teng, XW1
Dillon, CT1
Hambley, TW1
Lay, PA1
Davies, NM1
Bhandari, SV1
Parikh, JK1
Bothara, KG1
Chitre, TS1
Lokwani, DK1
Devale, TL1
Modhave, NS1
Pawar, VS1
Panda, S1
Fujino, H1
Murayama, T1
Carrasco-Pozo, C2
Speisky, H2
Brunser, O1
Pastene, E1
Gotteland, M2
Kholova, D1
Tlaskalova-Hogenova, H1
Pavlik, M1
Mizgier, ML1
O'Donovan, DJ1
Baetiong, A1
Adams, K1
Chen, A1
Smith, EO1
Adams, JM1
Weisman, LE1
Rainsford, KD1
Stetsko, PI1
Sirko, SP1
Debski, S1
BUCHMANN, E1
Troost, FJ1
Saris, WH1
Brummer, RJ1
Petruzzelli, M1
Moschetta, A1
Renooij, W1
de Smet, MB1
Palasciano, G1
Portincasa, P1
van Erpecum, KJ1
Dalby, AB1
Frank, DN1
St Amand, AL1
Bendele, AM1
Pace, NR1
Laudanno, O1
Vasconcelos, L1
Catalana, J1
Cesolari, J1
Kirkova, M1
Kesiova, M1
Konstantinova, S1
Alexandrova, A1
Petrov, L1
Tsvetanova, E1
Todorov, S1
Dial, EJ1
Darling, RL1
Lichtenberger, LM1
Onose, J1
Imai, T1
Hasumura, M1
Ueda, M1
Ozeki, Y1
Hirose, M1
Lehtinen, K2
Kaarela, K2
Mäkisara, P1
Holttinen, K1
Gordin, A2
Mizushima, Y1
Guobis, G1
Iushenaite, Ia1
Tabata, K2
Okabe, S2
Schiantarelli, P1
Cadel, S1
Kawai, K1
Tamura, S1
Morimoto, S1
Ishii, H1
Kuzuna, S1
Felder, M1
Bachmann, F1
Cunnane, SC1
Huston, GJ1
Beale, JP1
Thillainayagam, AV1
Tabaqchali, S1
Warrington, SJ1
Farthing, MJ1
Uddenfeldt, P1
Leden, I1
Rubin, B1
Ettarh, RR1
Carr, KE1
Young, WB1
Silberstein, SD1
Turek, JJ1
Schoenlein, IA1
Ogiso, T1
Iwaki, M1
Tanino, T1
Nagai, T1
Ueda, Y1
Muraoka, O1
Tanabe, G1
Balint, GA1
Meddings, JB1
Gibbons, I1
Hofmann, S1
Trnka, HJ1
Metzenroth, H1
Frank, E1
Ritschl, P1
Salzer, M1
Playford, RJ1
Floyd, DN1
Macdonald, CE1
Calnan, DP1
Adenekan, RO1
Johnson, W1
Goodlad, RA1
Marchbank, T1
Beck, PL1
Xavier, R1
Lu, N1
Nanda, NN1
Dinauer, M1
Podolsky, DK1
Seed, B1
Yamagiwa, S1
Yoshida, Y1
Halder, RC1
Weerasinghe, A1
Sugahara, S1
Asakura, H1
Abo, T1
Ojala, R1
Ruuska, T1
Karikoski, R1
Ikonen, RS1
Tammela, O1
Buisseret, PD1
Youlten, LF1
Heinzelmann, DI1
Lessof, MH1
Bramble, MG1
Record, CO1
Mirelli, E2
Fichera, G2
Volpe, AD1
Lasala, M1
Valtonen, EJ1
Busson, M1
Ammitzbøll, F1
Kajanoja, P1
Vesanto, T1
Rosenbaum, ES1
Barbieri, EJ1
Ciccolunghi, SN1
Schubiger, BI1
Reddrop, R1
Peltola, P1
Grahame, R1
Burry, HC1
Zutshi, D1
Mason, M1
Fossgreen, J1
Kirchheiner, B1
Petersen, FO1
Tophoj, E1
Zachariae, E1
Tausch, G2
Bröll, H2
Dunky, A1
Eberl, R2
Shriver, DA1
Dove, PA1
White, CB1
Sandor, A1
Rosenthale, ME1
Swift, GL1
Arnold, J1
Williams, GT1
Williams, BD1
Rhodes, J1
Khan, F1
Jones, RD1
Baynes, RE1
Nimitz, CT1
Oberto, G1
Conz, A1
Giachetti, C1
Galli, CL1
Schlegel, SI1
Paulus, HE1
Inman, WH1
Heere, LP1
Ahonen, M1
Forsberg, S1
Luukkainen, R1
Martio, J1
Mutru, O1
Nykänen, E1
Nykänen, P1
Pesonen, J1
Altman, R1
Calabro, JJ1
Sotka, S1
Nuutila, J1
Burch, FX1
Aguwa, CN1
Marcolongo, R1
Kinsella, TD1
MacKenzie, KR1
Kim, SO1
Johnson, LG1
Caruso, I1
Rooney, PJ1
Watkins, C1
Ahola, SJ1
Gray, GI1
Dick, WC1
Andersson, S1
Sun, DC1
Cuthbert, MF1
Klein, G1
Fellner, S1
Fellner, R1
Sturrock, RD1
Hart, FD1
Rubin, A1
Chernish, SM1
Crabtree, R1
Gruber, CM1
Helleberg, L1
Rodda, BE1
Warrick, P1
Wolen, RL1
Ridolfo, AS1
Sochor, H1
Bontoux, D1
Green, AY1
Green, D1
Rothermich, NO2
Baumann, JC1
Hoffmann, U1
Henrard, JC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Resistant Starch Consumption on Zinc Hemostasis in Malawian Children at Risk for Zinc Deficiency[NCT01811836]20 participants (Actual)Interventional2013-03-31Completed
GpCRC Pediatric Gastroparesis Registry 2: Characterization and Clinical Course of Symptoms and Gastric Emptying in Pediatric, Adolescent, and Young Adult Participants With Symptoms of Gastroparesis[NCT05981300]216 participants (Anticipated)Observational [Patient Registry]2024-02-28Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for indomethacin and Cholera Infantum

ArticleYear
To Feed or Not to Feed: A Critical Overview of Enteral Feeding Management and Gastrointestinal Complications in Preterm Neonates with a Patent Ductus Arteriosus.
    Nutrients, 2019, Dec-27, Volume: 12, Issue:1

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus

2019
[Novel anti-cancer effects of indomethacin: exploring the cyclooxygenase-inhibition-independent effects].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2011, Volume: 137, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; CD36 Anti

2011
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofena

1981
Drug-induced gastrointestinal disease.
    Drugs, 1978, Volume: 15, Issue:6

    Topics: Adrenal Cortex Hormones; Cathartics; Colon; Constipation; Diarrhea; Enterocolitis, Pseudomembranous;

1978
Non-steroidal and analgesic therapy in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen

1986

Trials

30 trials available for indomethacin and Cholera Infantum

ArticleYear
Recombinant human lactoferrin ingestion attenuates indomethacin-induced enteropathy in vivo in healthy volunteers.
    European journal of clinical nutrition, 2003, Volume: 57, Issue:12

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Bli

2003
Tolerability and efficacy of a slow-release indomethacin tablet in ankylosing spondylitis.
    British journal of rheumatology, 1984, Volume: 23, Issue:1

    Topics: Adult; Capsules; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug To

1984
Pro-drugs of non-steroidal anti-inflammatory agents.
    European journal of rheumatology and inflammation, 1983, Volume: 6, Issue:2

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Gast

1983
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofena

1981
[Fenclofenac in the treatment of rheumatoid arthritis (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Dec-26, Volume: 105, Issue:52

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Gastrointestinal Disea

1980
Interrelationships between Helicobacter pylori infection, nonsteroidal antiinflammatory drugs and gastroduodenal disease. A prospective study in healthy volunteers.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cyclodextrins; Double-Blind Meth

1994
A double-blind comparison of oral ketoprofen 'controlled release' and indomethacin suppository in the treatment of rheumatoid arthritis with special regard to morning stiffness and pain on awakening.
    Current medical research and opinion, 1993, Volume: 13, Issue:3

    Topics: Administration, Rectal; Adult; Aged; Ambulatory Care; Arthritis, Rheumatoid; Central Nervous System

1993
Prostaglandin-synthesis inhibitors in prophylaxis of food intolerance.
    Lancet (London, England), 1978, Apr-29, Volume: 1, Issue:8070

    Topics: Acute Disease; Adult; Animals; Aspirin; Bivalvia; Chickens; Clinical Trials as Topic; Dairy Products

1978
Endoscopic study of the gastro-intestinal tolerance of glucamethacin.
    Current medical research and opinion, 1978, Volume: 5, Issue:8

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic;

1978
A comparative study on ibuprofen (Brufen) and indomethacin in non-articular rheumatism.
    Scandinavian journal of rheumatology, 1978, Volume: 7, Issue:3

    Topics: Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Gastrointestinal Diseases; H

1978
Fenbufen and indomethacin in the treatment of rheumatoid arthritis. A comparative double-blind, crossover study.
    Scandinavian journal of rheumatology. Supplement, 1979, Issue:23

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biphenyl Compounds; Cli

1979
Naproxen and indomethacin in the treatment of primary dysmenorrhea.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1979, Volume: 87

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Gastroi

1979
A double-blind cross-over study of ketoprofen and phenylbutazone in rheumatoid arthritis.
    Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0

    Topics: Analgesics; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Gastroi

1976
Ketoprofen -- a new anti-rheumatic agent.
    Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0

    Topics: Analgesics; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Gastroi

1976
Ketoprofen in rheumatoid arthritis: its tolerance and therapeutic effect.
    Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0

    Topics: Adult; Aged; Analgesics; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evalua

1976
Clinical evaluation of ketoprofen (19.583 R.P.) in rheumatoid arthritis. Double-blind cross-over comparison with indomethacin.
    Scandinavian journal of rheumatology. Supplement, 1976, Volume: 1976, Issue:0

    Topics: Adult; Aged; Analgesics; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evalua

1976
Comparative clinical trial with a new substance, Diftalone, versus indomethacin in 30 patients affected with rheumatoid arthritis.
    Scandinavian journal of rheumatology, 1976, Volume: 5, Issue:3

    Topics: Administration, Oral; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Female; Gast

1976
A comparison of upper gastrointestinal mucosal damage by standard and delayed-release indomethacin.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Double-Blind Method; Duodenal Ulcer; Du

1992
Piroxicam in acute musculoskeletal disorders and sport injuries.
    European journal of rheumatology and inflammation, 1987, Volume: 8, Issue:1

    Topics: Acute Disease; Adult; Athletic Injuries; Central Nervous System Diseases; Clinical Trials as Topic;

1987
A six-month follow-up study of a slow-release indomethacin tablet in rheumatic diseases.
    Clinical rheumatology, 1987, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Diseases; Clinical Trials as Topic; Delayed-A

1987
International experiences with diclofenac in osteoarthritis.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Dis

1986
Efficacy of diclofenac in ankylosing spondylitis.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Adult; Aged; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Gastrointestinal Dis

1986
Comparison of a slow-release indomethacin tablet and naproxen in osteoarthrosis.
    Current medical research and opinion, 1985, Volume: 9, Issue:7

    Topics: Adult; Aged; Central Nervous System Diseases; Clinical Trials as Topic; Delayed-Action Preparations;

1985
Evaluation of the safety of isoxicam.
    The American journal of medicine, 1985, Oct-18, Volume: 79, Issue:4B

    Topics: Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation

1985
Evaluation of indomethacin by a controlled, cross-over technique in 30 patients with ankylosing spondylitis.
    Canadian Medical Association journal, 1967, Jun-03, Volume: 96, Issue:22

    Topics: Alkaline Phosphatase; Anemia, Hypochromic; Aspartate Aminotransferases; Aspirin; Central Nervous Sys

1967
A short-term double-blind controlled trial of prenazone (DA 2370) in rheumatoid arthritis.
    Current medical research and opinion, 1974, Volume: 2, Issue:1

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Alkenes; Analgesics; Anti-Inflammatory

1974
[Indomethacin in rheumatic diseases with special reference to ophthalmologic studies].
    Medizinische Klinik, 1972, Feb-25, Volume: 67, Issue:8

    Topics: Allopurinol; Arthritis, Rheumatoid; Azathioprine; Blood Cells; Capsules; Clinical Trials as Topic; E

1972
Double-blind cross-over comparison of indomethacin, flurbiprofen, and placebo in ankylosing spondylitis.
    Annals of the rheumatic diseases, 1974, Volume: 33, Issue:2

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents; Biphenyl Compounds; Blood Sedimentation; Clinical Tr

1974
A profile of the physiological disposition and gastro-intestinal effects of fenoprofen in man.
    Current medical research and opinion, 1974, Volume: 2, Issue:9

    Topics: Administration, Oral; Adult; Age Factors; Animals; Anti-Inflammatory Agents; Aspirin; Biotransformat

1974
[Gastric protection with sulfated polysaccharides. Study during anti-inflammatory treatment].
    La Presse medicale, 1971, Sep-11, Volume: 79, Issue:37

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Antagonism; Drug T

1971

Other Studies

65 other studies available for indomethacin and Cholera Infantum

ArticleYear
Antiinflammatory agents. 4. Syntheses and biological evaluation of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid and 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Acetamides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzeneacetam

1990
Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Biological Availability; Cyclooxygenase Inhibitors; Ga

1986
1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
    Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena

1997
Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jan-18, Volume: 97, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line

2000
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
    Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholesterol; Cysteine; Drug

2004
Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Acetates; Amides; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthri

2008
NSAIDs disrupt intestinal homeostasis by suppressing macroautophagy in intestinal epithelial cells.
    Scientific reports, 2019, 10-10, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Epithelial Cells; Gastrointestinal Diseases; Goble

2019
Protection against Gut Inflammation and Sepsis in Mice by the Autodigested Product of the Lingzhi Medicinal Mushroom, Ganoderma lingzhi (Agaricomycetes).
    International journal of medicinal mushrooms, 2018, Volume: 20, Issue:9

    Topics: Animals; beta-Glucans; Cells, Cultured; Cytokines; Fungal Polysaccharides; Gastrointestinal Diseases

2018
Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity.
    Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:11

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Disease Models

2017
Anti-inflammatory and phytochemical properties of twelve medicinal plants used for treating gastro-intestinal ailments in South Africa.
    Journal of ethnopharmacology, 2009, Jun-22, Volume: 123, Issue:2

    Topics: Alkaloids; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors;

2009
Type and distribution of indomethacin-induced lesions in the gastrointestinal tract of rat.
    Neuro endocrinology letters, 2009, Volume: 30 Suppl 1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Diseases; I

2009
Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:4

    Topics: Acetylglucosaminidase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Carcinogens;

2010
Design, synthesis, and evaluation of anti-inflammatory, analgesic, ulcerogenicity, and nitric oxide releasing studies of novel indomethacin analogs as non-ulcerogenic derivatives.
    Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Gastrointestinal Diseases

2010
Apple peel polyphenols protect against gastrointestinal mucosa alterations induced by indomethacin in rats.
    Journal of agricultural and food chemistry, 2011, Jun-22, Volume: 59, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chlorogenic Acid; Disease Models, Animal; Flavonoid

2011
Absorption kinetics of 5-aminosalicylic acid in rat: influence of indomethacin-induced gastrointestinal lesions and Escherichia Coli Nissle 1917 medication.
    Neuro endocrinology letters, 2011, Volume: 32 Suppl 1

    Topics: Absorption; Animals; Anti-Inflammatory Agents, Non-Steroidal; Escherichia coli; Gastrointestinal Dis

2011
Differential protective effects of quercetin, resveratrol, rutin and epigallocatechin gallate against mitochondrial dysfunction induced by indomethacin in Caco-2 cells.
    Chemico-biological interactions, 2012, Feb-05, Volume: 195, Issue:3

    Topics: Adenosine Triphosphate; Caco-2 Cells; Catechin; Drug Interactions; Electron Transport Complex I; Gas

2012
Necrotizing enterocolitis and gastrointestinal complications after indomethacin therapy and surgical ligation in premature infants with patent ductus arteriosus.
    Journal of perinatology : official journal of the California Perinatal Association, 2003, Volume: 23, Issue:4

    Topics: Birth Weight; Cardiac Surgical Procedures; Cardiovascular Agents; Ductus Arteriosus, Patent; Enteroc

2003
Gastrointestinal mucosal injury following repeated daily oral administration of conventional formulations of indometacin and other non-steroidal anti-inflammatory drugs to pigs: a model for human gastrointestinal disease.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:5

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; D

2003
THE ANTIRHEUMATIC EFFECT OF INDOMETHACIN.
    Acta rheumatologica Scandinavica, 1965, Volume: 11

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antirheumatic Agents; Arthritis; Arthritis, Rheu

1965
Indomethacin enhances bile salt detergent activity: relevance for NSAIDs-induced gastrointestinal mucosal injury.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Biological Transport; Diseas

2006
Culture-independent analysis of indomethacin-induced alterations in the rat gastrointestinal microbiota.
    Applied and environmental microbiology, 2006, Volume: 72, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ecosystem; Enterococcus faecalis; Female; Gastroin

2006
Anti-inflammatory effect of bioflora probiotic administered orally or subcutaneously with live or dead bacteria.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:12

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bi

2006
In vivo effects of amtolmetin guacyl on lipid peroxidation and antioxidant defence systems in different models of gastrointestinal injury.
    Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Disease Models, Animal; Ethanol; Gas

2007
Importance of biliary excretion of indomethacin in gastrointestinal and hepatic injury.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:8 Pt 2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biliary Tract; Chemical and Drug Induced Liver Inj

2008
Evaluation of subchronic toxicity of dietary administered Cry1Ab protein from Bacillus thuringiensis var. Kurustaki HD-1 in F344 male rats with chemically induced gastrointestinal impairment.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bacillus thuringiensis; Bacillu

2008
Effects of 16,16-dimethyl-PGE2-methyl ester on aspirin- and indomethacin-induced gastric and intestinal lesions in mini pigs.
    Digestion, 1983, Volume: 26, Issue:2

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Female; Gastrointestinal Diseases; Indomethacin; I

1983
Piroxicam pharmacologic activity and gastrointestinal damage by oral and rectal route. Comparison with oral indometacin and phenylbutazone.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Migration Inhibition; E

1981
Pharmacology of 4-benzyol-1-indancarboxylic acid (TAI-901) and 4-(4-methylbenzoyl)-1-indancarboxylic acid (TAI-908).
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dogs; Female; Gastrointestinal Disease

1982
[Non-steroidal antirheumatics: side-effects and interactions].
    Schweizerische medizinische Wochenschrift, 1982, Aug-28, Volume: 112, Issue:35

    Topics: Anemia, Aplastic; Anti-Inflammatory Agents, Non-Steroidal; Coumarins; Drug Interactions; Gastrointes

1982
Maternal essential fatty acid supplementation increases zinc absorption in neonatal rats: relevance to the defect in zinc absorption in acrodermatitis enteropathica.
    Pediatric research, 1982, Volume: 16, Issue:8

    Topics: Acrodermatitis; Animals; Arachidonic Acids; Fatty Acids, Essential; Female; Gastrointestinal Disease

1982
Local buccal mucosal effects of aspirin, indomethacin and isoxepac: their relationship to gastrointestinal damage.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:5

    Topics: Acetates; Anti-Inflammatory Agents; Aspirin; Cheek; Dibenzoxepins; Gastrointestinal Diseases; Humans

1981
Indomethacin and CME.
    Journal - American Intra-Ocular Implant Society, 1980, Volume: 6, Issue:1

    Topics: Aged; Cataract Extraction; Edema; Female; Gastrointestinal Diseases; Humans; Indomethacin; Macula Lu

1980
Structural and morphometric analysis of murine small intestine after indomethacin administration.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:9

    Topics: Animals; Duodenum; Gastrointestinal Diseases; Ileum; Indomethacin; Intestine, Small; Jejunum; Male;

1993
Hemicrania continua and symptomatic medication overuse.
    Headache, 1993, Volume: 33, Issue:9

    Topics: Adult; Ergotamine; Female; Gastrointestinal Diseases; Humans; Indomethacin; Middle Aged; Migraine Di

1993
Indomethacin-induced gastrointestinal ulcers in rats: effects of dietary fatty acids and endotoxin.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:3

    Topics: Animals; Corn Oil; Dietary Fats, Unsaturated; Endotoxins; Fatty Acids; Gastrointestinal Diseases; In

1993
Pharmacokinetics of indomethacin ester prodrugs: gastrointestinal and hepatic toxicity and the hydrolytic capacity of various tissues in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:9

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Li

1996
A novel approach to reduce the unwanted gastric side-effects of orally administered non-steroidal anti-inflammatory drugs in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1997, Volume: 49, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Drug Therapy, Comb

1997
Discrimination of site-specific alterations in gastrointestinal permeability in the rat.
    Gastroenterology, 1998, Volume: 114, Issue:1

    Topics: Animals; Aspirin; Biological Transport; Cyclooxygenase Inhibitors; Digestive System; Disease Models,

1998
Discrimination of site-specific alterations in gastrointestinal permeability in the rat.
    Gastroenterology, 1998, Volume: 114, Issue:1

    Topics: Animals; Aspirin; Biological Transport; Cyclooxygenase Inhibitors; Digestive System; Disease Models,

1998
Discrimination of site-specific alterations in gastrointestinal permeability in the rat.
    Gastroenterology, 1998, Volume: 114, Issue:1

    Topics: Animals; Aspirin; Biological Transport; Cyclooxygenase Inhibitors; Digestive System; Disease Models,

1998
Discrimination of site-specific alterations in gastrointestinal permeability in the rat.
    Gastroenterology, 1998, Volume: 114, Issue:1

    Topics: Animals; Aspirin; Biological Transport; Cyclooxygenase Inhibitors; Digestive System; Disease Models,

1998
General short-term indomethacin prophylaxis to prevent heterotopic ossification in total hip arthroplasty.
    Orthopedics, 1999, Volume: 22, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthropl

1999
Bovine colostrum is a health food supplement which prevents NSAID induced gut damage.
    Gut, 1999, Volume: 44, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cell Culture Techniques; Cell Division; Ce

1999
Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice.
    Gastroenterology, 2000, Volume: 119, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; DNA-Binding Proteins; Enteritis; Fucosy

2000
Mechanisms involved in enteropathy induced by administration of nonsteroidal antiinflammatory drugs (NSAIDS).
    Digestive diseases and sciences, 2001, Volume: 46, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Appendix; Colon; Fluorescent Antibody Technique; G

2001
Gastroesophageal endoscopic findings and gastrointestinal symptoms in preterm neonates with and without perinatal indomethacin exposure.
    Journal of pediatric gastroenterology and nutrition, 2001, Volume: 32, Issue:2

    Topics: Biopsy; Case-Control Studies; Ductus Arteriosus, Patent; Endoscopy, Gastrointestinal; Enteral Nutrit

2001
Inhibition by aspirin of gastrointestinal toxicity induced by indomethacin in polyarthritic rats.
    Toxicology and applied pharmacology, 1979, Volume: 49, Issue:3

    Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Disease Models, Animal; Dose-Response Relation

1979
Comparisons of tolerability findings in international clinical trials.
    Rheumatology and rehabilitation, 1979, Volume: Suppl 2

    Topics: Arthritis, Rheumatoid; Aspirin; Cardiovascular System; Clinical Trials as Topic; Diclofenac; Drug To

1979
[Gastrointestinal diseases caused by drugs, especially by anti-inflammatory agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1978, Volume: Suppl

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Dogs; Gastrointestinal Diseases; Indometh

1978
A profile of the gastrointestinal toxicity of aspirin, indomethacin, oxaprozin, phenylbutazone, and fentiazac in arthritic and Lewis normal rats.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:1

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Aspirin; Body Weigh

1977
Nonsteroidal anti-inflammatory drug toxicosis in dogs and cats: 240 cases (1989-1990)
    Journal of the American Veterinary Medical Association, 1992, Aug-01, Volume: 201, Issue:3

    Topics: Accidents; Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cat Diseases; C

1992
Evaluation of the toxicity of indomethacin in a 4-week study, by oral route, in the marmoset (Callithrix jacchus).
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 15, Issue:4

    Topics: Administration, Oral; Animals; Blood Cell Count; Blood Chemical Analysis; Body Weight; Callithrix; F

1990
Non-steroidal anti-inflammatory drugs: assessment of risks.
    European journal of rheumatology and inflammation, 1987, Volume: 8, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Central Nervous Syste

1987
Gastrointestinal effects of the extracts of Rhigiocarya racemifera (Menispermaceae).
    General pharmacology, 1985, Volume: 16, Issue:4

    Topics: Animals; Cimetidine; Female; Gastrointestinal Diseases; Glycosides; Indomethacin; Ligation; Male; Mi

1985
[Undesired collateral effects of indomethacin].
    La Clinica terapeutica, 1972, Feb-29, Volume: 60, Issue:4

    Topics: Arthritis, Rheumatoid; Gastrointestinal Diseases; Headache; Histamine Release; Humans; Indomethacin

1972
[Undesired collateral effects of antirheumatic drugs: indomethacin].
    La Clinica terapeutica, 1972, Feb-29, Volume: 60, Issue:4

    Topics: Arthritis, Rheumatoid; Drug Eruptions; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Pa

1972
[Side effects of drugs. 2. Gastrointestinal side effects].
    Lakartidningen, 1969, Dec-15, Volume: 66

    Topics: Adrenocorticotropic Hormone; Caffeine; Drug-Related Side Effects and Adverse Reactions; Gastrointest

1969
Iatrogenic gastrointestinal diseases in the aged.
    Geriatrics, 1972, Volume: 27, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Cathartics; Chemical and Drug Induced Li

1972
Adverse reactions to non-steroidal antirheumatic drugs.
    Current medical research and opinion, 1974, Volume: 2, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Chemical and Drug Induced Liv

1974
[Gastro-duodenal tolerance of some drugs with analgesic effect. Clinico-endoscopic considerations].
    Minerva medica, 1974, Feb-24, Volume: 65, Issue:14

    Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Digestive System; Duodenal Ulcer; Esop

1974
[Tolerance of long-term indomethacin treatment].
    Wiener klinische Wochenschrift, 1972, Jun-30, Volume: 84, Issue:26

    Topics: Adult; Aged; Arthritis, Rheumatoid; Central Nervous System Diseases; Chronic Disease; Drug Tolerance

1972
Gout.
    British medical journal, 1974, Mar-09, Volume: 1, Issue:5905

    Topics: Allopurinol; Blood Cell Count; Cell Movement; Colchicine; Diet; Drug Synergism; Gastrointestinal Dis

1974
Wy 23205, a new non-steroidal anti-inflammatory agent.
    British journal of pharmacology, 1971, Volume: 42, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Bradykinin; Gastrointestinal Diseases; Guinea

1971
An extended study of indomethacin. I. Clinical pharmacology.
    JAMA, 1966, Feb-14, Volume: 195, Issue:7

    Topics: Adult; Aged; Arthritis; Central Nervous System Diseases; Fibromyalgia; Gastrointestinal Diseases; He

1966
[5 years of experience with indomethacin].
    La Clinica terapeutica, 1967, Jun-15, Volume: 41, Issue:5

    Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Eye; Female; Fibromyalgia; Gastroint

1967
[Experiences with indomethacin in extra-articular rheumatism].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:11

    Topics: Gastrointestinal Diseases; Humans; Indomethacin; Neuralgia; Rheumatic Diseases; Spinal Diseases

1971
[Current analgesic anti-inflammatory drugs].
    La Presse medicale, 1970, May-27, Volume: 78, Issue:26

    Topics: Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver In

1970
A nonsteroidal anti-inflammatory agent. Indomethacin (indocin).
    JAMA, 1966, May-16, Volume: 196, Issue:7

    Topics: Arthritis, Rheumatoid; Central Nervous System Diseases; Gastrointestinal Diseases; Humans; Indometha

1966