indomethacin has been researched along with Cholelithiasis in 19 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin is an effective inhibitor of prostaglandin synthetase and has recently been demonstrated to inhibit inflammatory fluid secretion into the gallbladder in experimental cholecystitis." | 5.26 | Indomethacin intravenously--a new way for effective relief of biliary pain: a double-blind study in man. ( Jansson, R; Svanvik, J; Thornell, E, 1981) |
| "Experimental cholelithiasis is associated with elevated biliary calcium concentration and altered gallbladder absorption." | 1.29 | Converting gallbladder absorption to secretion: the role of intracellular calcium. ( Abedin, MZ; Cates, JA; Giurgiu, DI; Karam, JA; Moser, AJ; Roslyn, JJ, 1996) |
| "Indomethacin is an effective inhibitor of prostaglandin synthetase and has recently been demonstrated to inhibit inflammatory fluid secretion into the gallbladder in experimental cholecystitis." | 1.26 | Indomethacin intravenously--a new way for effective relief of biliary pain: a double-blind study in man. ( Jansson, R; Svanvik, J; Thornell, E, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, HJ | 1 |
| Lee, SK | 1 |
| Kim, MH | 1 |
| Seo, DW | 1 |
| Min, YI | 1 |
| Martínez-Cuesta, MA | 1 |
| Moreno, L | 1 |
| Morillas, J | 1 |
| Ponce, J | 1 |
| Esplugues, JV | 1 |
| Svanvik, J | 3 |
| Thornell, E | 4 |
| Jansson, R | 3 |
| Brotschi, EA | 1 |
| Lamorte, WW | 2 |
| Williams, LF | 1 |
| Wexels, JC | 1 |
| Kotwall, CA | 1 |
| Clanachan, AS | 1 |
| Baer, HP | 1 |
| Scott, GW | 1 |
| Palleschi, M | 1 |
| Marci, M | 1 |
| Dumont, AE | 1 |
| Martelli, AB | 1 |
| Schinella, RA | 1 |
| Valensi, QJ | 1 |
| Schulz, M | 1 |
| Hanisch, E | 1 |
| Güldütüna, S | 1 |
| von Ritter, C | 1 |
| Niemeyer, A | 1 |
| Lange, V | 1 |
| Möhrle, W | 1 |
| Richter, WO | 1 |
| von Meyer, L | 1 |
| Brandl, H | 1 |
| del Pozo, R | 1 |
| Jüngst, D | 1 |
| Forse, A | 1 |
| El-Beheiry, H | 1 |
| Butler, PO | 1 |
| Pace, RF | 1 |
| Moser, AJ | 1 |
| Abedin, MZ | 1 |
| Cates, JA | 1 |
| Giurgiu, DI | 1 |
| Karam, JA | 1 |
| Roslyn, JJ | 1 |
| Kral, JG | 1 |
| O'Donnell, LJ | 1 |
| Wilson, P | 1 |
| Guest, P | 1 |
| Catnach, SM | 1 |
| McLean, A | 1 |
| Wickham, JE | 1 |
| Fairclough, PD | 1 |
| O'Leary, DP | 1 |
| Scott, TE | 1 |
| Booker, ML | 1 |
| Stevenson, J | 1 |
| Jacyna, MR | 1 |
| Ross, PE | 1 |
| Hopwood, D | 1 |
| Bouchier, IA | 1 |
| Viksmoen, L | 1 |
| Grüner, OP | 1 |
| Hertzenberg, S | 1 |
| Laerum, E | 1 |
| Waaler, G | 1 |
1 review available for indomethacin and Cholelithiasis
| Article | Year |
|---|---|
[Current studies of the clinical aspects and drug therapy of biliary calculosis in the elderly].
Topics: Age Factors; Aged; Anti-Bacterial Agents; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholel | 1981 |
6 trials available for indomethacin and Cholelithiasis
| Article | Year |
|---|---|
Indomethacin in the treatment of patients with biliary pain. A controlled clinical study.
Topics: Adult; Aged; Cholelithiasis; Clinical Trials as Topic; Double-Blind Method; Humans; Indomethacin; In | 1983 |
Mechanisms in the development of acute cholecystitis and biliary pain. A study on the role of prostaglandins and effects of indomethacin.
Topics: Acute Disease; Animals; Biliary Tract; Cats; Cholecystitis; Cholelithiasis; Clinical Trials as Topic | 1982 |
Indomethacin decreases viscosity of gallbladder bile in patients with cholesterol gallstone disease.
Topics: Administration, Oral; Adult; Aged; Bile; Cholelithiasis; Cholesterol; Female; Humans; Indomethacin; | 1993 |
Indomethacin and ketorolac given preoperatively are equally effective in reducing early postoperative pain after laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Lap | 1996 |
Indomethacin and postprandial gallbladder emptying.
Topics: Adult; Cholelithiasis; Drug Administration Schedule; Eating; Female; Gallbladder Emptying; Humans; I | 1992 |
[Treatment of acute biliary and kidney/urether pain. A comparative study of the effects of intravenous injections of buprenorphine, indomethacin and pethidine].
Topics: Adolescent; Adult; Aged; Analgesics; Buprenorphine; Cholelithiasis; Clinical Trials as Topic; Female | 1986 |
12 other studies available for indomethacin and Cholelithiasis
| Article | Year |
|---|---|
Cyclooxygenase-2 mediates mucin secretion from epithelial cells of lipopolysaccharide-treated canine gallbladder.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Cholelithiasis | 2003 |
Influence of cholecystitis state on pharmacological response to cholecystokinin of isolated human gallbladder with gallstones.
Topics: Acetylcholine; Adult; Atropine; Cholecystectomy; Cholecystitis; Cholecystokinin; Cholelithiasis; Dru | 2003 |
Effect of dietary cholesterol and indomethacin on cholelithiasis and gallbladder motility in guinea pig.
Topics: Animals; Cholecystokinin; Cholelithiasis; Cholesterol, Dietary; Female; Gallbladder; Gastrointestina | 1984 |
[Indomethacin in renal and gallstones pain].
Topics: Adult; Aged; Cholelithiasis; Female; Humans; Indomethacin; Kidney Calculi; Male; Middle Aged; Pain | 1984 |
Effects of prostaglandins on motility of gallbladders removed from patients with gallstones.
Topics: Cholelithiasis; Gallbladder; Gastrointestinal Motility; Humans; Indomethacin; Prostaglandin Antagoni | 1984 |
Transmural fluid movement in the freshly excised human gallbladder.
Topics: Absorption; Adolescent; Adult; Aged; Biological Transport; Cholecystectomy; Cholelithiasis; Female; | 1982 |
Indomethacin intravenously--a new way for effective relief of biliary pain: a double-blind study in man.
Topics: Adult; Aged; Blood Pressure; Cholelithiasis; Double-Blind Method; Female; Gallbladder; Humans; Indom | 1981 |
[In vitro contractility of the musculature of human gallbladders with and without gallstones--relevance of the prostaglandin system for CCK regulated motoricity].
Topics: Adult; Aged; Aged, 80 and over; Cholecystokinin; Cholelithiasis; Culture Techniques; Dose-Response R | 1993 |
Converting gallbladder absorption to secretion: the role of intracellular calcium.
Topics: Animals; Calcimycin; Calcium; Chlorides; Cholelithiasis; Cyclic AMP; Dogs; Gallbladder; Indomethacin | 1996 |
Inhibition of prostaglandin synthesis as a treatment for biliary pain.
Topics: Cholelithiasis; Colic; Female; Humans; Indomethacin; Injections, Intravenous; Male; Middle Aged; Pro | 1979 |
Inhibition of prostaglandin synthesis fails to prevent gallbladder mucin hypersecretion in the cholesterol-fed prairie dog.
Topics: Animals; Calcimycin; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Female; Gallbladder; Indomet | 1991 |
Sodium transport in the diseased human gallbladder and the effects of indomethacin.
Topics: Biological Transport, Active; Cholelithiasis; Gallbladder; Humans; In Vitro Techniques; Indomethacin | 1988 |