indomethacin has been researched along with Cholecystitis in 31 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Cholecystitis: Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an open, randomized prospective clinical trial the analgesic effect of indomethacin and ketobemidon was compared in 67 patients with acute cholecystitis (28 received 5 mg ketobemidon and 39 received 50 mg indomethacin)." | 9.06 | [Comparison of indomethacin and ketobemidone as analgesics in acute cholecystitis]. ( Holmlund, D; Mätzsch, T, 1986) |
| "Indomethacin was recently shown to have a potent analgesic effect on biliary pain." | 9.05 | Indomethacin reduces raised intraluminal gallbladder pressure in acute cholecystitis. ( Jansson, R; Svanvik, J; Thornell, E, 1985) |
| "The aim of this study was to determine whether the prostaglandin synthase inhibitor indomethacin reverses the inflammation and abnormal gallbladder contractility that occur after common bile duct ligation (CBDL), a model of acute cholecystitis." | 7.71 | Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis. ( Bartula, LL; James, AN; Myers, SI; Parkman, HP; Ryan, JP; Thomas, RM, 2001) |
| "In an open, randomized prospective clinical trial the analgesic effect of indomethacin and ketobemidon was compared in 67 patients with acute cholecystitis (28 received 5 mg ketobemidon and 39 received 50 mg indomethacin)." | 5.06 | [Comparison of indomethacin and ketobemidone as analgesics in acute cholecystitis]. ( Holmlund, D; Mätzsch, T, 1986) |
| "Indomethacin was recently shown to have a potent analgesic effect on biliary pain." | 5.05 | Indomethacin reduces raised intraluminal gallbladder pressure in acute cholecystitis. ( Jansson, R; Svanvik, J; Thornell, E, 1985) |
| "The aim of this study was to determine whether the prostaglandin synthase inhibitor indomethacin reverses the inflammation and abnormal gallbladder contractility that occur after common bile duct ligation (CBDL), a model of acute cholecystitis." | 3.71 | Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis. ( Bartula, LL; James, AN; Myers, SI; Parkman, HP; Ryan, JP; Thomas, RM, 2001) |
| "Gallbladder inflammation was evaluated by quantitation of luminal water transport and tissue myeloperoxidase levels." | 1.29 | The production of experimental cholecystitis by endotoxin. ( Deshpande, YG; Feinstein, WK; Kaminski, DL, 1994) |
| "Gallbladder inflammation was evaluated by beta-glucuronidase and myeloperoxidase tissue concentrations and by a histologic scoring system." | 1.28 | The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor. ( Andrus, CH; Deshpande, YG; German, D; Kaminski, DL, 1990) |
| "Indomethacin treatment inhibited PG synthesis in all BDL groups but only decreased the inflammation score in the 6 and 24 hour BDL groups." | 1.28 | Common bile ligation in the rabbit: an appropriate model for investigating the relationship of endogenous gallbladder prostanoid synthesis with evolving acute inflammation. ( Bartula, LL; Haley-Russell, D; Myers, SI; Nabzdyk, W, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (45.16) | 18.7374 |
| 1990's | 12 (38.71) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Santosa, A | 1 |
| Yang, SS | 1 |
| Chandran, NS | 1 |
| Martínez-Cuesta, MA | 1 |
| Moreno, L | 1 |
| Morillas, J | 1 |
| Ponce, J | 1 |
| Esplugues, JV | 1 |
| Andre, E | 1 |
| Gazzieri, D | 1 |
| Bardella, E | 1 |
| Ferreira, J | 1 |
| Mori, MA | 1 |
| Saul, VV | 1 |
| Bader, M | 1 |
| Calixto, JB | 1 |
| De Giorgio, R | 1 |
| Corinaldesi, R | 1 |
| Geppetti, P | 1 |
| Trevisani, M | 1 |
| Thornell, E | 9 |
| Svanvik, J | 8 |
| Jansson, R | 3 |
| Mätzsch, T | 2 |
| Holmlund, D | 2 |
| Zettergren, L | 1 |
| Myers, SI | 5 |
| Inman, LR | 1 |
| Kalley-Taylor, B | 2 |
| Riva, A | 2 |
| Bartula, L | 3 |
| Kaminski, DL | 4 |
| Feinstein, WK | 1 |
| Deshpande, YG | 4 |
| Nilsson, B | 3 |
| Friman, S | 1 |
| Thune, A | 1 |
| Jivegård, L | 2 |
| Turnage, R | 1 |
| Kadesky, K | 1 |
| Delbro, DS | 1 |
| Prystowsky, JB | 1 |
| Rege, RV | 1 |
| Farghaly, M | 1 |
| Khoursheed, M | 1 |
| Dashti, H | 1 |
| Thulesius, O | 1 |
| Chandler, CF | 1 |
| Lane, JS | 1 |
| Ferguson, P | 1 |
| Thompson, JE | 1 |
| Ashley, SW | 1 |
| Parkman, HP | 1 |
| James, AN | 1 |
| Thomas, RM | 1 |
| Bartula, LL | 2 |
| Ryan, JP | 1 |
| Andrus, CH | 1 |
| German, D | 1 |
| Haley-Russell, D | 1 |
| Nabzdyk, W | 1 |
| Daneshmand, H | 1 |
| Dean, P | 1 |
| Bukhave, K | 1 |
| Rask-Madsen, J | 1 |
| Pellegrini, CA | 1 |
| Allen, B | 1 |
| Bernhoft, R | 1 |
| Way, LW | 1 |
| Jönsson, PE | 1 |
| Erichsen, C | 1 |
| Holmin, T | 1 |
| Petersson, BA | 1 |
| Qualy, J | 1 |
| Thomas, LA | 1 |
| Akizuki, M | 1 |
| Fujimori, I | 1 |
| Katsu, M | 1 |
7 trials available for indomethacin and Cholecystitis
| Article | Year |
|---|---|
Mechanisms in the development of acute cholecystitis and biliary pain. A study on the role of prostaglandins and effects of indomethacin.
Topics: Acute Disease; Animals; Biliary Tract; Cats; Cholecystitis; Cholelithiasis; Clinical Trials as Topic | 1982 |
Prospective evaluation of early versus delayed laparoscopic cholecystectomy for treatment of acute cholecystitis.
Topics: Acute Disease; Administration, Rectal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, S | 2000 |
Effect of short-term indomethacin treatment on the clinical course of acute obstructive cholecystitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Body Temperature; Cholecystitis; Double-B | 1991 |
[Comparison of indomethacin and ketobemidone as analgesics in acute cholecystitis].
Topics: Acute Disease; Analgesics, Opioid; Cholecystectomy; Cholecystitis; Clinical Trials as Topic; Drug Th | 1986 |
Indomethacin reduces raised intraluminal gallbladder pressure in acute cholecystitis.
Topics: Acute Disease; Adult; Aged; Analgesics; Cholecystitis; Clinical Trials as Topic; Female; Gallbladder | 1985 |
Double-blind evaluation of intravenous indomethacin and oxycone-papaverine in the treatment of acute biliary pain.
Topics: Adolescent; Adult; Aged; Analgesics; Biliary Tract Diseases; Cholecystitis; Clinical Trials as Topic | 1985 |
[Antipyretic effects of indomethacin in acute infectious diseases--a double blind test].
Topics: Adolescent; Adult; Aged; Cholecystitis; Colitis; Female; Fever; Humans; Indomethacin; Infections; Ma | 1971 |
24 other studies available for indomethacin and Cholecystitis
| Article | Year |
|---|---|
DRESS Masquerading as Acute Cholecystitis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cholecystitis; Drug Hypersensitivity Syndrome; Female | 2020 |
Influence of cholecystitis state on pharmacological response to cholecystokinin of isolated human gallbladder with gallstones.
Topics: Acetylcholine; Adult; Atropine; Cholecystectomy; Cholecystitis; Cholecystokinin; Cholelithiasis; Dru | 2003 |
Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder.
Topics: Adult; Aged; Atropine; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Chole | 2008 |
Studies on experimental cholecystitis.
Topics: Animals; Biological Transport; Cats; Cholecystitis; Gallbladder; Indomethacin; Movement; Pain | 1983 |
Effects of indomethacin on gallbladder pressure in patients with acute cholecystitis.
Topics: Acute Disease; Cholecystitis; Gallbladder; Humans; Indomethacin; Pressure | 1983 |
Analgetic effects of indomethacin (Confortid) compared to Ketogin in patients with acute cholecystitis.
Topics: Acute Disease; Allylamine; Amines; Analgesics; Cholecystitis; Drug Combinations; Female; Humans; Ind | 1983 |
[Indomethacin treatment of biliary pain].
Topics: Biliary Tract Diseases; Cholecystitis; Humans; Indomethacin; Pain; Prostaglandins | 1982 |
Gallbladder function in experimental cholecystitis.
Topics: Animals; Bile; Cats; Cholecystitis; Female; Gallbladder; Humans; Indomethacin; Liver; Male; Prostagl | 1981 |
Effects of raised intraluminal pressure on gallbladder function and hepatic bile outflow in the cat.
Topics: Animals; Bile; Cats; Cholecystitis; Cholestasis; Disease Models, Animal; Gallbladder; Indomethacin; | 1981 |
Increased intragallbladder pressure stimulates gallbladder eicosanoid release.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cholecystitis; Dinoprostone; Gallbladder; Hydrostatic Pressur | 1994 |
The production of experimental cholecystitis by endotoxin.
Topics: Alprazolam; Animals; Cats; Cholecystitis; Gallbladder; Indomethacin; Lipopolysaccharides; Platelet A | 1994 |
Inflammation reduces mucosal secretion of hydrogen ions and impairs concentrating function and luminal acidification in feline gallbladder.
Topics: Amiloride; Animals; Bicarbonates; Body Fluids; Cats; Cholecystitis; Cyclooxygenase Inhibitors; Diure | 1995 |
Platelet activating factor (PAF) stimulates release of PGI2 from inflamed rabbit gallbladder cell cultures.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antibodies; Cells, Cultured; Cholecystitis; Cytochrome P-450 | 1995 |
L-arginine reverses indomethacin-induced inhibition of inflammatory fluid secretion of the feline gall bladder.
Topics: Animals; Arginine; Cats; Cholecystitis; Chronic Disease; Cyclooxygenase Inhibitors; Disease Models, | 1997 |
Interleukin-1 mediates guinea pig gallbladder inflammation in vivo.
Topics: Animals; Cholecystitis; Dinoprostone; Guinea Pigs; Indomethacin; Interleukin-1; Lipopolysaccharides | 1997 |
Gallbladder motility in laparoscopic cholecystectomy specimens.
Topics: Acute Disease; Animals; Carbachol; Cholecystectomy, Laparoscopic; Cholecystitis; Chronic Disease; Cu | 1997 |
Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholecystitis; Common Bile Duct; Ga | 2001 |
Human cholecystitis is associated with increased gallbladder prostaglandin I2 and prostaglandin E2 synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Cholecystitis; Dinoprostone; Epoprostenol; Gallbladd | 1992 |
The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Absorption; Acute Disease; Animals; Body Water; Cats; Cholecystitis; G | 1990 |
Common bile ligation in the rabbit: an appropriate model for investigating the relationship of endogenous gallbladder prostanoid synthesis with evolving acute inflammation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cholecystitis; Common Bile Duct; Dinoprostone; Disease Models | 1990 |
Prostanoids and leukotrienes in experimental feline cholecystitis.
Topics: Animals; Calcium; Cats; Cholecystitis; Indomethacin; Ionophores; Leukotrienes; Lysophosphatidylcholi | 1990 |
Prostaglandin E2 formation by the gall bladder in experimental cholecystitis.
Topics: Animals; Cats; Cholecystitis; Dilatation; Dinoprostone; Female; Gallbladder; Indomethacin; Lysophosp | 1986 |
Transport of fluid and biliary lipids in the canine gallbladder in experimental cholecystitis.
Topics: Animals; Bile; Bile Acids and Salts; Body Fluids; Cholecystitis; Cholesterol; Dogs; Epithelium; Fast | 1986 |
The role of prostaglandins in feline experimental cholecystitis.
Topics: Animals; Cats; Cholecystitis; Dogs; Gallbladder; Guinea Pigs; Humans; In Vitro Techniques; Indometha | 1985 |