indomethacin has been researched along with Chest Injuries in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the study is to verify the efficacy of the pharmacological blockade of the systemic inflammatory response syndrome (SIRS) in serious blunt chest injuries, and to identify whether the administration of indomethacin as a cyclooxygenase inhibitor could prevent a multiorgan dysfunction (MODS) and a multiorgan failure (MOF)." | 5.11 | Systemic inflammatory response syndrome (SIRS) in serious chest injuries: is a pharmacological blockade effective? ( Cervinka, V; Havlícek, K; Motycka, V; Siller, J, 2005) |
| " The aim is also to find out if the administration of indomethacin as a cyclooxygenase inhibitor could prevent multiorgan dysfunction (MODS) and multiorgan failure (MOF)." | 5.10 | [Pharmacologic prevention of SIRS (systemic inflammatory response syndrome) in severe thoracic injuries]. ( Fortová, M; Grofová, Z; Havlícek, K; Motycka, V; Siller, J; Vanác, J, 2003) |
| "126 patients with blunt chest injuries were evaluated during 33 months." | 2.72 | [Blunt thoracic injury and the oxidation stress]. ( Fortová, M; Grofová, Z; Havlíek, K; Linda, B; Motycka, V; Siller, J, 2006) |
| "126 patients with blunt chest injuries were evaluated during 33 months." | 2.72 | [SIRS and serious blunt thoracic injuries]. ( Fortová, M; Grofová, Z; Havlícek, K; Linda, B; Motycka, V; Siller, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Motycka, V | 4 |
| Havlícek, K | 3 |
| Siller, J | 4 |
| Grofová, Z | 3 |
| Vanác, J | 1 |
| Fortová, M | 3 |
| Cervinka, V | 1 |
| Havlíek, K | 1 |
| Linda, B | 2 |
| Melton, SM | 1 |
| Davis, KA | 1 |
| Moomey, CB | 1 |
| Fabian, TC | 1 |
| Proctor, KG | 1 |
4 trials available for indomethacin and Chest Injuries
| Article | Year |
|---|---|
[Pharmacologic prevention of SIRS (systemic inflammatory response syndrome) in severe thoracic injuries].
Topics: Cyclooxygenase Inhibitors; Humans; Indomethacin; Multiple Organ Failure; Premedication; Systemic Inf | 2003 |
Systemic inflammatory response syndrome (SIRS) in serious chest injuries: is a pharmacological blockade effective?
Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studi | 2005 |
[Blunt thoracic injury and the oxidation stress].
Topics: Antioxidants; Cyclooxygenase Inhibitors; Humans; Indomethacin; Injury Severity Score; Oxidative Stre | 2006 |
[SIRS and serious blunt thoracic injuries].
Topics: Adult; Cyclooxygenase Inhibitors; Humans; Indomethacin; Injury Severity Score; Middle Aged; Respirat | 2006 |
1 other study available for indomethacin and Chest Injuries
| Article | Year |
|---|---|
Mediator-dependent secondary injury after unilateral blunt thoracic trauma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Transfusion; Cerebrovascular Disorders; Cont | 1999 |