indomethacin has been researched along with Chagas Cardiomyopathy in 2 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gomes, JA | 1 |
| Molica, AM | 1 |
| Keesen, TS | 1 |
| Morato, MJ | 1 |
| de Araujo, FF | 1 |
| Fares, RC | 1 |
| Fiuza, JA | 1 |
| Chaves, AT | 1 |
| Pinheiro, V | 1 |
| Nunes, Mdo C | 1 |
| Correa-Oliveira, R | 1 |
| da Costa Rocha, MO | 1 |
| de Bracco, MM | 1 |
| Sterin-Borda, L | 1 |
| Fink, S | 1 |
| Finiasz, M | 1 |
| Borda, E | 1 |
2 other studies available for indomethacin and Chagas Cardiomyopathy
| Article | Year |
|---|---|
Inflammatory mediators from monocytes down-regulate cellular proliferation and enhance cytokines production in patients with polar clinical forms of Chagas disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigens, Protozoan; B-Lymphocytes; Cell Proliferation; Cel | 2014 |
Stimulatory effect of lymphocytes from Chagas' patients on spontaneously beating rat atria.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Catechols; Chagas Cardiomyopathy; Chagas Disease; | 1984 |