indomethacin has been researched along with Cerebrovascular Disorders in 12 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin pretreatment of aortae from 20 week old SHRSP restored acetylcholine-induced EDR to a level comparable with that in age-matched WKY." | 1.29 | Enhancement of endothelium-dependent relaxation in the aorta from stroke-prone spontaneously hypertensive rats at developmental stages of hypertension. ( Hamano, M; Mashiko, S; Onda, T; Tomita, I; Tomita, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lorenzo Fernández, P | 1 |
| Agostoni, A | 1 |
| de Boer, AC | 1 |
| Genton, E | 1 |
| Turpie, AG | 1 |
| Nagaoka, A | 1 |
| Kakihana, M | 1 |
| Iwatsuka, H | 1 |
| Onda, T | 1 |
| Mashiko, S | 1 |
| Hamano, M | 1 |
| Tomita, I | 1 |
| Tomita, T | 1 |
| McIntyre, M | 1 |
| Hamilton, CA | 1 |
| Rees, DD | 1 |
| Reid, JL | 1 |
| Dominiczak, AF | 1 |
| Melton, SM | 1 |
| Davis, KA | 1 |
| Moomey, CB | 1 |
| Fabian, TC | 1 |
| Proctor, KG | 1 |
| Kulkarni, M | 1 |
| Armstead, WM | 1 |
| Takemoto, F | 1 |
| Miyanoshita, A | 1 |
| Shimamura, K | 1 |
| Sunano, S | 1 |
| Endou, H | 1 |
| Walker, V | 1 |
| Pickard, JD | 1 |
| Sugimoto, T | 1 |
| Tobian, L | 1 |
| Ganguli, MC | 1 |
| Bakunts, GO | 1 |
| Koval'chuk, LV | 1 |
| Cheknev, SB | 1 |
| Ul'ianova, TIu | 1 |
| Pavliuk, AS | 1 |
2 reviews available for indomethacin and Cerebrovascular Disorders
| Article | Year |
|---|---|
Chemistry, measurement, and clinical significance of platelet specific proteins.
Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Coagulation; Blood Coagulation Factors; Blood P | 1982 |
Prostaglandins, thromboxane, leukotrienes and the cerebral circulation in health and disease.
Topics: Animals; Arachidonic Acids; Brain; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Cerebro | 1985 |
10 other studies available for indomethacin and Cerebrovascular Disorders
| Article | Year |
|---|---|
[Neuroprotection by aspirin in cerebrovascular pathology].
Topics: Adenosine Triphosphate; Algorithms; Amino Acid Transport System X-AG; Animals; Aspirin; Brain Ischem | 2002 |
[Current status of medical treatment].
Topics: Aminophylline; Animals; Anticoagulants; Aspirin; Barbiturates; Brain Ischemia; Cerebrovascular Disor | 1980 |
Effects of prostaglandin inhibitors on the onset of proteinuria and stroke in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Carbazoles; Cerebrovascular Disorders; Hypertension; Indomethacin; Prostagl | 1981 |
Enhancement of endothelium-dependent relaxation in the aorta from stroke-prone spontaneously hypertensive rats at developmental stages of hypertension.
Topics: Acetylcholine; Animals; Aorta; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Endothel | 1994 |
Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Carbachol; Cerebrovascular Disorders; Ditioca | 1997 |
Mediator-dependent secondary injury after unilateral blunt thoracic trauma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Transfusion; Cerebrovascular Disorders; Cont | 1999 |
Superoxide generation links nociceptin/orphanin FQ (NOC/oFQ) release to impaired N-methyl-D-aspartate cerebrovasodilation after brain injury.
Topics: Animals; Animals, Newborn; Cerebral Arteries; Cerebrovascular Circulation; Cerebrovascular Disorders | 2000 |
Intranephron PGE2 production in stroke-prone spontaneously hypertensive rats.
Topics: Aging; Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Calcimycin; Cerebrovascul | 1990 |
High potassium diets protect against dysfunction of endothelial cells in stroke-prone spontaneously hypertensive rats.
Topics: Acetylcholine; Administration, Oral; Animals; Aorta, Thoracic; Biological Products; Cerebrovascular | 1988 |
[Functional activity of natural killers and lymphocyte antibody-dependent cytotoxicity in patients with acute disorders of the cerebral circulation].
Topics: Acute Disease; Aged; Antibody-Dependent Cell Cytotoxicity; Cells, Cultured; Cerebrovascular Disorder | 1988 |