indomethacin has been researched along with Cerebral Intraventricular Haemorrhage in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine if antenatal variables affect the risk of spontaneous intestinal perforation (SIP) among preterm infants when prophylactic indomethacin is used." | 8.02 | Antenatal Risk Factors Associated with Spontaneous Intestinal Perforation in Preterm Infants Receiving Postnatal Indomethacin. ( Arnautovic, TI; Keszler, M; Laptook, AR; Longo, JL; Trail-Burns, EJ; Tucker, R, 2021) |
| "To determine the effect of concomitant administration of prophylactic indomethacin and early enteral feeds on the risk of spontaneous intestinal perforation (SIP) in extremely low-birth-weight (ELBW) infants, and to describe the variation in prophylactic indomethacin use in Canada." | 7.85 | Effect of prophylactic indomethacin administration and early feeding on spontaneous intestinal perforation in extremely low-birth-weight infants. ( Cieslak, Z; Claveau, M; Shah, PS; Sherlock, R; Stavel, M; Wong, J, 2017) |
| "To determine if antenatal variables affect the risk of spontaneous intestinal perforation (SIP) among preterm infants when prophylactic indomethacin is used." | 4.02 | Antenatal Risk Factors Associated with Spontaneous Intestinal Perforation in Preterm Infants Receiving Postnatal Indomethacin. ( Arnautovic, TI; Keszler, M; Laptook, AR; Longo, JL; Trail-Burns, EJ; Tucker, R, 2021) |
| "To determine the effect of concomitant administration of prophylactic indomethacin and early enteral feeds on the risk of spontaneous intestinal perforation (SIP) in extremely low-birth-weight (ELBW) infants, and to describe the variation in prophylactic indomethacin use in Canada." | 3.85 | Effect of prophylactic indomethacin administration and early feeding on spontaneous intestinal perforation in extremely low-birth-weight infants. ( Cieslak, Z; Claveau, M; Shah, PS; Sherlock, R; Stavel, M; Wong, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Isayama, T | 1 |
| Kusuda, S | 1 |
| Reichman, B | 1 |
| Lee, SK | 1 |
| Lehtonen, L | 1 |
| Norman, M | 1 |
| Adams, M | 1 |
| Bassler, D | 1 |
| Helenius, K | 1 |
| Hakansson, S | 1 |
| Yang, J | 1 |
| Jain, A | 1 |
| Shah, PS | 2 |
| Mitra, S | 1 |
| Scrivens, A | 1 |
| von Kursell, AM | 1 |
| Disher, T | 1 |
| Arnautovic, TI | 1 |
| Longo, JL | 1 |
| Trail-Burns, EJ | 1 |
| Tucker, R | 1 |
| Keszler, M | 1 |
| Laptook, AR | 1 |
| Nelin, TD | 1 |
| Pena, E | 1 |
| Giacomazzi, T | 1 |
| Lee, S | 1 |
| Logan, JW | 1 |
| Moallem, M | 1 |
| Bapat, R | 1 |
| Shepherd, EG | 1 |
| Nelin, LD | 1 |
| McNally, MA | 1 |
| Soul, JS | 1 |
| Stavel, M | 1 |
| Wong, J | 1 |
| Cieslak, Z | 1 |
| Sherlock, R | 1 |
| Claveau, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Early Targeted Ibuprofene Treatment of Patent Ductus Arteriosus (PDA) on Long Term Neurodevelopmental Outcome in Very Premature Infants (TRIOCAPI)[NCT01630278] | Phase 3 | 363 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for indomethacin and Cerebral Intraventricular Haemorrhage
| Article | Year |
|---|---|
Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Cerebral Intraventricular Hemorrhage; Chron | 2020 |
Pharmacologic Prevention and Treatment of Neonatal Brain Injury.
Topics: Adrenal Cortex Hormones; Allopurinol; Anesthetics, Inhalation; Anticonvulsants; Antioxidants; Cerebr | 2019 |
4 other studies available for indomethacin and Cerebral Intraventricular Haemorrhage
| Article | Year |
|---|---|
Neonatal Intensive Care Unit-Level Patent Ductus Arteriosus Treatment Rates and Outcomes in Infants Born Extremely Preterm.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Canada; Cardiovascular Surgical Procedures; Cerebral | 2020 |
Antenatal Risk Factors Associated with Spontaneous Intestinal Perforation in Preterm Infants Receiving Postnatal Indomethacin.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Case-Control Studi | 2021 |
Outcomes following indomethacin prophylaxis in extremely preterm infants in an all-referral NICU.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Bronchopulmonary Dysplasia; Cerebral Intraven | 2017 |
Effect of prophylactic indomethacin administration and early feeding on spontaneous intestinal perforation in extremely low-birth-weight infants.
Topics: Canada; Cerebral Intraventricular Hemorrhage; Databases, Factual; Enteral Nutrition; Female; Gestati | 2017 |